LOCUS       NM_013790               5826 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ATP-binding cassette, sub-family C member 5 (Abcc5),
            transcript variant 1, mRNA.
ACCESSION   NM_013790
VERSION     NM_013790.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5826)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5826)
  AUTHORS   Li,V.L., He,Y., Contrepois,K., Liu,H., Kim,J.T., Wiggenhorn,A.L.,
            Tanzo,J.T., Tung,A.S., Lyu,X., Zushin,P.H., Jansen,R.S.,
            Michael,B., Loh,K.Y., Yang,A.C., Carl,C.S., Voldstedlund,C.T.,
            Wei,W., Terrell,S.M., Moeller,B.C., Arthur,R.M., Wallis,G.A., van
            de Wetering,K., Stahl,A., Kiens,B., Richter,E.A., Banik,S.M.,
            Snyder,M.P., Xu,Y. and Long,J.Z.
  TITLE     An exercise-inducible metabolite that suppresses feeding and
            obesity
  JOURNAL   Nature 606 (7915), 785-790 (2022)
   PUBMED   35705806
REFERENCE   3  (bases 1 to 5826)
  AUTHORS   Chambers,I.G., Kumar,P., Lichtenberg,J., Wang,P., Yu,J.,
            Phillips,J.D., Kane,M.A., Bodine,D. and Hamza,I.
  TITLE     MRP5 and MRP9 play a concerted role in male reproduction and
            mitochondrial function
  JOURNAL   Proc Natl Acad Sci U S A 119 (6) (2022)
   PUBMED   35121660
  REMARK    GeneRIF: MRP5 and MRP9 play a concerted role in male reproduction
            and mitochondrial function.
REFERENCE   4  (bases 1 to 5826)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5826)
  AUTHORS   Cyranka,M., Veprik,A., McKay,E.J., van Loon,N., Thijsse,A.,
            Cotter,L., Hare,N., Saibudeen,A., Lingam,S., Pires,E.,
            Larraufie,P., Reimann,F., Gribble,F., Stewart,M., Bentley,E.,
            Lear,P., McCullagh,J., Cantley,J., Cox,R.D. and de Wet,H.
  TITLE     Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of
            Circulating GLP-1
  JOURNAL   Obesity (Silver Spring) 27 (8), 1292-1304 (2019)
   PUBMED   31338999
REFERENCE   6  (bases 1 to 5826)
  AUTHORS   Borst,P., Evers,R., Kool,M. and Wijnholds,J.
  TITLE     A family of drug transporters: the multidrug resistance-associated
            proteins
  JOURNAL   J Natl Cancer Inst 92 (16), 1295-1302 (2000)
   PUBMED   10944550
  REMARK    Review article
REFERENCE   7  (bases 1 to 5826)
  AUTHORS   Schriml,L.M. and Dean,M.
  TITLE     Identification of 18 mouse ABC genes and characterization of the
            ABC superfamily in Mus musculus
  JOURNAL   Genomics 64 (1), 24-31 (2000)
   PUBMED   10708515
REFERENCE   8  (bases 1 to 5826)
  AUTHORS   Suzuki,T., Sasaki,H., Kuh,H.J., Agui,M., Tatsumi,Y., Tanabe,S.,
            Terada,M., Saijo,N. and Nishio,K.
  TITLE     Detailed structural analysis on both human MRP5 and mouse mrp5
            transcripts
  JOURNAL   Gene 242 (1-2), 167-173 (2000)
   PUBMED   10721709
REFERENCE   9  (bases 1 to 5826)
  AUTHORS   Konig,J., Nies,A.T., Cui,Y., Leier,I. and Keppler,D.
  TITLE     Conjugate export pumps of the multidrug resistance protein (MRP)
            family: localization, substrate specificity, and MRP2-mediated drug
            resistance
  JOURNAL   Biochim Biophys Acta 1461 (2), 377-394 (1999)
   PUBMED   10581368
  REMARK    Review article
REFERENCE   10 (bases 1 to 5826)
  AUTHORS   Borst,P., Evers,R., Kool,M. and Wijnholds,J.
  TITLE     The multidrug resistance protein family
  JOURNAL   Biochim Biophys Acta 1461 (2), 347-357 (1999)
   PUBMED   10581366
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BB603250.1 and BC090629.1.
            
            On Jun 3, 2005 this sequence version replaced NM_013790.1.
            
            Summary: The membrane-associated protein encoded by this gene is a
            member of the superfamily of ATP-binding cassette (ABC)
            transporters. ABC proteins transport various molecules across
            extra- and intra-cellular membranes. ABC genes are divided into
            seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20,
            White). This protein is a member of the MRP subfamily which is
            involved in multi-drug resistance. The human protein functions in
            the cellular export of its substrate, cyclic nucleotides. This
            export contributes to the degradation of phosphodiesterases and
            possibly an elimination pathway for cyclic nucleotides. Studies
            show that the human protein provides resistance to thiopurine
            anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV
            drug 9-(2-phosphonylmethoxyethyl)adenine. Two alternatively spliced
            transcript variants encoding distinct isoforms have been found for
            this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) is the longer transcript and
            encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090629.1, SRR9219380.56249.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                BB603250.1         2-44
            44-5826             BC090629.1         1-5783
FEATURES             Location/Qualifiers
     source          1..5826
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 12.41 cM"
     gene            1..5826
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /note="ATP-binding cassette, sub-family C member 5"
                     /db_xref="GeneID:27416"
                     /db_xref="MGI:MGI:1351644"
     exon            1..147
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            148..328
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            329..486
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            487..642
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            643..790
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            791..1024
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1198
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1346
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1495
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1603
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..1960
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2032
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..2157
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2158..2230
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2231..2434
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2578
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2579..2678
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2679..2863
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2864..3010
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3140
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3294
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            3295..3423
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            3424..3610
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            3611..3700
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            3701..3890
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            3891..4050
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            4051..4129
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            4130..4243
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            4244..4408
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     exon            4409..5811
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4867..4872
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /note="hexamer: ATTAAA"
     polyA_site      4904
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /note="major polyA site"
     regulatory      5787..5792
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /note="hexamer: AATAAA"
     polyA_site      5811
                     /gene="Abcc5"
                     /gene_synonym="2900011L11Rik; Abcc5a; Abcc5b; Mrp5"
                     /note="major polyA site"
ORIGIN      
        1 gattcccttc ggtcttgcgc aagctttgtg catcgcgctt gcgcgttgtg ggggactatg
       61 ccgctataaa ggcttgtttt gctcagggtc cgatgttcgc gagcgtgccc gggctgtttg
      121 ctctcgtgtg gggaggctgg ggtgcagaat ttctgaagtg aaaggaggag tctgcaccct
      181 ggtcctctgt gtggtgaaga tgaaagatat tgacatggga aaagaatata tcatccccag
      241 ccctgggtac agaagtgaca gggacagaag cgctgtacca gggcaacaca gagaccccga
      301 ggaacccagg ttccggagaa caagatcgtt ggaatgccaa gatgctctcg aaacagcagc
      361 ccgagttgag gggctttccc tggatatctc tgtgcattct catctccaaa ttctggacga
      421 ggagcattct aagggaaaat accaccatgg tttaagtgtc ctgaagccct tccggaccac
      481 taccaagcac cagcacccag tggacaatgc tggacttttc tcctacatga ccttttcatg
      541 gctctctcct ctggcccgag tggttcacaa gaagggggag ctgttaatgg aggatgtgtg
      601 gcctttgtcc aagtatgagt cttctgatgt gaacagcaga agactagaga gactgtggca
      661 agaagagctg aatgaagttg ggccagacgc tgcctccctg cgaagggttg tgtggatctt
      721 ttgccgcacc aggctcatcc tgtccatcgt gtgcctgatg atcacgcagt tggctggctt
      781 cagtggacca gccttcgtgg tgaagcacct cttggagtac acccaggcaa cagagtctaa
      841 cctgcagtac agcttgctgt tagtgttagg cctactcctg acagaagttg tacgctcctg
      901 gtcacttgca ctgacttggg cattgaatta tcgaactggt gtccggttgc ggggggctat
      961 cctgactatg gcattcaaga agatcctgaa gttaaagaac attaaagaaa agtccctagg
     1021 ggagctcatc aatatctgct ccaatgatgg gcaaaggatg tttgaggcag ccgctgtggg
     1081 cagcttgctg gctggaggac ctgttgttgc catcttgggc atgatttata atgtaatcat
     1141 cctaggaccc acgggcttcc tgggatcagc ggtttttatc ctcttttatc cagcaatgat
     1201 gttcgtgtca cggctaactg catatttcag gagaaagtgt gtagctgcca cagatgaccg
     1261 tgtccagaag atgaatgaag ttcttaccta cattaaattc attaaaatgt atgcctgggt
     1321 caaagcgttt tctcagtgtg tgcaaaaaat ccgagaggag gaacgtcgga tattggagaa
     1381 agccgggtac tttcagagca tcactgttgg agtggctcct attgtggtag tgatcgccag
     1441 tgtggtgacg ttctccgttc acatgaccct gggcttccat ctgactgcgg cacaggcctt
     1501 cacagtggtg actgtcttca attccatgac ttttgcttta aaagtaacac cattctcagt
     1561 gaagtccctc tctgaagcat cagtggctgt tgacagattt aagagtttgt ttctaatgga
     1621 agaggttcac atgataaaga acaaaccggc cagtcctcac atcaagatag agatgaaaaa
     1681 tgccaccttg gcatgggact cctcccactc cagtatacag aactcgccca agctgacccc
     1741 caaaatgaaa aaagacaaga gggctaccag gggcaagaaa gagaagtcga ggcagctgca
     1801 acacactgag caccaggcgg tgctggcaga acagaaagga cacctcctcc tggacagtga
     1861 cgagcggccc agcccggaag aggaagaagg caagcagatc cacacaggga gcctgcgcct
     1921 gcagaggaca ctgtacaaca ttgacttaga aattgaagag ggcaaactgg ttggaatctg
     1981 cggcagtgtg ggaagtggaa aaacctctct cgtttcagcc attttaggcc agatgacgct
     2041 tttggagggc agcattgccg tcagtgggac ctttgcttat gtggcccaac aggcctggat
     2101 tctcaatgcc actctgagag acaacattct ctttgggaag gaatttgatg aagagagata
     2161 caactcagtg ctgaatagct gctgcctgcg gcctgacttg gccattctcc ccaacagcga
     2221 cctgactgag attggagagc gaggagccaa cctgagtggt ggacagcgcc agagaatcag
     2281 ccttgctaga gccttgtaca gtgatagaag catctacatc ctggatgacc ccctcagtgc
     2341 cttagatgcc catgtgggca accacatctt caacagtgct atccggaagc gcctcaagtc
     2401 taagacggtt ctgtttgtta cacaccagtt acagtatctg gtcgattgtg atgaggtgat
     2461 cttcatgaag gaaggctgta tcacagagag aggtacccat gaggagctga tgaacttaaa
     2521 tggggattac gctacgattt ttaataacct gttgctggga gagacacccc cagttgagat
     2581 taattcgaaa aaggaagcta ctggttcaca aaaatcacaa gacaagggcc ctaagccagg
     2641 gtcagtgaag aaggagaagg cggtgaagtc ggaggaaggg cagcttgtgc aggtggagga
     2701 gaaagggcaa ggttctgtgc cttggtcagt ctactgggtc tacatccagg ctgcaggggg
     2761 ccccttggct ttcctggtca tcatggtcct cttcatgctg aatgtgggca gcactgcctt
     2821 cagcacctgg tggcttagct actggatcaa gcaaggaagc gggaacagca cagtgtatca
     2881 agggaacaga agcttcgtga gtgacagcat gaaggacaac cccttcatgc agtactacgc
     2941 cagcatctac gccctctcca tggcagtcat gctgatcttg aaagccattc gaggagttgt
     3001 cttcgtcaag ggcacactga gagcctcctc ccggctccat gatgagctat tccgaaggat
     3061 ccttaggagc cccatgaagt tttttgatac taccccaaca ggaaggattc tcaacaggtt
     3121 ttccaaagac atggatgaag tggatgtgcg gctgccgttc caggctgaga tgtttattca
     3181 gaatgtaatc ctggtgttct tctgtgttgg aatgattgct ggagtcttcc catggttcct
     3241 cgtggcggtg gggcctctcc tcatcctctt ctcacttctc cacattgtct ccagggtcct
     3301 gattcgtgag ctaaagcggt tggacaatat cacgcagtct cctttcctct cccacatcac
     3361 gtctagcatt cagggcctgg ccaccatcca tgcctacaac aaaaggcagg agtttttaca
     3421 caggtatcag gagctcctgg atgacaacca ggctcccttt ttcctgttca cctgtgcaat
     3481 gaggtggctg gcagtgcggc tggacctcat cagcattgcc ctgattacca ccactggcct
     3541 gatgattgtt ctcatgcatg gacagatccc ttcagcctat gcggggcttg ccatctccta
     3601 cgctgtgcag ttaactggac tattccagtt caccgtcaga ctggcatcgg agacagaagc
     3661 acggttcact tccgtggaga ggatcaacca ctatatcaag actctctctt tggaagcacc
     3721 tgccagaatc aagaacaagg ctcctcccca tgactggccc caggagggag aagtaacctt
     3781 tgagaatgca gaaatgagat accgggaaaa tctccctctg gtccttaaga aagtgtcctt
     3841 caccatcaag cccaaggaaa agataggcat tgtgggacga acagggtcag ggaagtcctc
     3901 tttggggatg gccctcttcc gtctggtgga gctatctgga ggctgcatca agattgatgg
     3961 aataagaatc agtgacatcg gcctggccga cctccgaagc aaactggcca tcattcctca
     4021 ggagccagtg ctgttcagtg gcactgtcag atcaaacctg gaccctttca accagtacac
     4081 ggaagaccag atctgggatg ctctagagag aacgcacatg aaggaatgta ttgcccagct
     4141 acctctgaaa cttgagtctg aagtaatgga gaacggggac aacttctctg ttggggaacg
     4201 gcagctgttg tgcatagcaa gagccctgct gcgtcactgt aagattctga ttttagatga
     4261 agctacagcc gctatggaca cagagacaga cttactgatc caggagacca tccgggaagc
     4321 atttgcggac tgcaccatgc tgaccattgc ccatcgcctg cacacagttc tgggctctga
     4381 caggatcatg gtgctggccc agggacaggt ggtggagttt gacaccccat cggtccttct
     4441 gtctaatgac agttcaagat tctatgccat gtttgctgct gcagagaaca aggtggctgt
     4501 caagggctga gtcctcccgt cctcgaagtc tcttcctcag agcattgcca ttctcttcct
     4561 ggtttgggcc cctcatcctg tcctgctgaa acttcgcctt tcccagtttt atctctcaca
     4621 caaccattca ggattagctg tgtgtttcac ttttaaggaa agtcatattt tgattattgt
     4681 atttattccc tattcactta aatgaaattt agtttttgtt cttaattgca ctcttaagag
     4741 gttcagggaa ccattactat aaatgttatc agtggcctat aatgaagctt tatatgtgta
     4801 gctatgtcta tatataattc tgtacatagc ctatatttac agtaaaatgt aagcggttta
     4861 ttttctatta aagtgagcac tgtgctaaca gcagtgcaca ctcatttcta tcgtttttgt
     4921 acagctgact gcactacagg tcattttgct cttagctgta gcaaaggcag attccgtctc
     4981 tagctggtcg tttcacggtg ctgggctctc taggcgtcca ggggagacac gcggcagcag
     5041 tgggccctcc atggcctgcc ccttgggctc cccagtggga acccagtata gtgggctgca
     5101 ggaggccttg cagagcaccg tgaattctca gggctcctgc tttcctgtct tggtgtcagc
     5161 tgctgtttat gttagagcag tgggcaaagc cagcccccac cccaccccca ttccctctca
     5221 ggaatgagaa cctctgcatt cctcagaggg agagcttctt tctgccttcc ttcttctgct
     5281 gccatttcta agcaagatcc agtctgctcc cagtgttcca tgcttcaggt tcctgaggct
     5341 ggtcgccaca gagttgtcga gttccctggc cagctggttc ccagccccag ggtccactgc
     5401 tgctgttgta ggtggcattt tcatttgcct gaccccaagg ctccagagct cagcaacagg
     5461 gctcaggatg gtggggtccg ttcttcctca ctttagtctc ctctgcaaag tctgcaccca
     5521 cccctcagca gctcttgcta atcagtgtct cacactggtg tagaagtttt ttgtactgta
     5581 aagagaccta cctcaggttg ctgattgctg tgtggtttgg tgcgctcttg cagaccccct
     5641 tgtgctctgg ggctcgtagc ttgggtgggt gtggttgcca ctgtcaccag tcgagtggtc
     5701 agcgtcgcat gtcgtgacca actagacatt ctgtcgcctt agcatgtttg ctaaatacct
     5761 tataaaagca aaaatatgaa aaagtgaata aaattatttt ggatttgtaa aaaaaaaaaa
     5821 aaaaaa
//
