LOCUS       NM_001278943            4617 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ATP-binding cassette, sub-family A member 16 (Abca16),
            transcript variant 1, mRNA.
ACCESSION   NM_001278943
VERSION     NM_001278943.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4617)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4617)
  AUTHORS   Chen,Z.Q., Annilo,T., Shulenin,S. and Dean,M.
  TITLE     Three ATP-binding cassette transporter genes, Abca14, Abca15, and
            Abca16, form a cluster on mouse Chromosome 7F3
  JOURNAL   Mamm Genome 15 (5), 335-343 (2004)
   PUBMED   15170222
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134434.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (isoform 1). The exon
            combination is inferred based on transcript alignments and protein
            homology.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               AC134434.4         71413-71532
            121-262             AC134434.4         92874-93015
            263-522             AC134434.4         95109-95368
            523-639             AC134434.4         97602-97718
            640-813             AC134434.4         100935-101108
            814-995             AC134434.4         114723-114904
            996-1130            AC134434.4         118817-118951
            1131-1248           AC134434.4         127451-127568
            1249-1403           AC134434.4         137187-137341
            1404-1559           AC134434.4         138980-139135
            1560-1770           AC134434.4         139474-139684
            1771-1921           AC134434.4         141487-141637
            1922-2020           AC134434.4         150878-150976
            2021-2192           AC134434.4         165102-165273
            2193-2490           AC134434.4         176302-176599
            2491-2737           AC134434.4         181727-181973
            2738-2942           AC134434.4         182118-182322
            2943-3162           AC134434.4         188764-188983
            3163-3327           AC134434.4         189452-189616
            3328-3515           AC134434.4         195379-195566
            3516-3641           AC134434.4         196520-196645
            3642-3836           AC134434.4         196875-197069
            3837-4024           AC134434.4         201785-201972
            4025-4195           AC134434.4         202340-202510
            4196-4386           AC134434.4         202876-203066
            4387-4460           AC134434.4         205763-205836
            4461-4617           AC134434.4         206423-206579
FEATURES             Location/Qualifiers
     source          1..4617
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 64.86 cM"
     gene            1..4617
                     /gene="Abca16"
                     /note="ATP-binding cassette, sub-family A member 16"
                     /db_xref="GeneID:233810"
                     /db_xref="MGI:MGI:2388711"
     exon            1..120
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            121..262
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            263..522
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            523..639
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     CDS             618..4601
                     /gene="Abca16"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ATP-binding cassette transporter sub-family A member 16;
                     ATP-binding cassette, sub-family A (ABC1), member 16"
                     /codon_start=1
                     /product="ATP-binding cassette transporter sub-family A
                     member 16 isoform 1"
                     /protein_id="NP_001265872.1"
                     /db_xref="GeneID:233810"
                     /db_xref="MGI:MGI:2388711"
                     /translation="MYITLCPARLAASAGNLLFFASFFPYNFISEYYGMLNLTTKITA
                     CLSANVALALGINILIKLEIQEIGVKWHNLWTPANLEDNLNFGYMLGMLLFDAFLYSL
                     VTWYVEAVFPGQCGVPQPWYFFLMRSYWFGKPKIRKTTEEAKCTPIVHNCYEAEPPNL
                     EAGIHIMHLHKEFKNKPAVNNLSLNIYEGQVTVLLGHNGAGKTTTLSVLTGRFAATRG
                     EAYINGYNISDNMIEVRKDLGFCPQHDLLFDDLTLSEHLFFYCMVKGIPQNINCEEID
                     RMLSAFNLQENYHTLSGSASGGVRRKLSIVLALMAGSKVVILDEPSSGMDPVSRRATW
                     DILQHYKHNRTILLTTHYMDEADVLGDRVAIMVRGTLHCCGSSVFLKQIYGAGYHIVM
                     EKQQYCDVDNIIAMIQQHVPGAVLENNIENELSFILPKKYVSRFETLFTELEMRQKAL
                     GIASFGASITTMEEVFVKVNKLATPQKSIQTIQPYYLAYRKMRQDEQQNVNMPINYSK
                     PNFPYLSEIATVKFNTGVPLYRQQFYSLFIKRALFISRNWKFMLLQIIVVMVVTTYLL
                     LALHLNNNDIPERELNLSHYGRTIVPYSTSGNSDLALNLTKNLNIFLKSKNQNLRKIR
                     GDMNDYILKNKDCHTFCLVALSIKVERNKTVLTIFFNNEAYHSPAISLSILDNILFMT
                     LSGPDASITVFNKPQPLPHYGSNIVPVNGLQIVQCLAFGISVVVGSFSIQTVTERTSQ
                     AKHIQFLTGVCVHTYWLSALLCDLIFFFFACCVLLAIFKFCQLEAFVVHYNFLDTILI
                     FMLYGWCVVPLTYIASFLFNSSTAAYIKITLFNYFSTMFSIIIYTIIQFYGNDFPNFV
                     HILIRAILMALPSYNLAMSISKYFDDYEVKRLCAREFKSIYLDCSDPYTQNNVYGFGE
                     HGIGKFLITLATIGLVFLLLLLSLESVSCSLKSFVFRNIIFYFYNKLRKGRNAIPSNQ
                     RTKEDEDEDIKKEKGKVFTLLLRLQNTPLLLNEVTKIYFKCPVVKAVKNISLVVKKSE
                     CFGLLGLNGAGKTTTFKMLTGEETITSGIAFIDGNSVTRTPRKIRSRIGYCPQTESVL
                     NHMTGRESLVMYARLWGVLEQDINEYVEAFLHSVHLEPIADQFIHTYSAGSKRRLSTA
                     IALMGKSSVVFLDEPSIGMDPVAQHLLWETITWICKTGKAIIITSHRMEECEALCTRL
                     AIMVKGRFTCLGTPQHVRKRFGHVYTLTVRINIAKDEDKVEEFKNFIKVTFPGNIKFQ
                     EFHGTIGYYIPSKEIYWGKVFAILEEAKVLFKLEDYSVKRVTLEQIFLTFANTDKMRT
                     YQEIKLQ"
     exon            640..813
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            814..995
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1130
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1248
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1403
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1559
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            1560..1770
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1921
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            1922..2020
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            2021..2192
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            2193..2490
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            2491..2737
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            2738..2942
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            2943..3162
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3327
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            3328..3515
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            3516..3641
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            3642..3836
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            3837..4024
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            4025..4195
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            4196..4386
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            4387..4460
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     exon            4461..4617
                     /gene="Abca16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4586..4591
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abca16"
                     /note="hexamer: AATAAA"
     polyA_site      4614
                     /gene="Abca16"
                     /note="major polyA site"
ORIGIN      
        1 agagcggttg atccgggtgt tgagggtgtt gagcggaagt gctgctcagg aaagactgga
       61 gcccagcagc gattcattgg aggaaacagg ggctgtggag gcggttgcta gctctgagtg
      121 gtaaaatatc acttgcgttt tgttggtgca cagaggacca tctggtggcc agacaagtta
      181 ggctggaaaa cgagacttct ctttcctaat catccttcta tacgacccag gaatccaaat
      241 tatcttgatg gaggaagtcc tgggtatatt aaggaaggat tcctggcagt acagcatgct
      301 ttggacaaga gcatcatgct gtatcatgaa agcagtgctg ggaaaaagct gtttgatgaa
      361 atcgacactg tgatacagag gtttccatac ccaagtcatc ctcaggataa actactttgg
      421 atttccagtc ctttcatccc attaatgttc atactcatgt tctcttccat tgtcctttcc
      481 atcatgcgat ccattgtgtt tgaaaaggaa aaacggttaa aggagtacca gctcataatg
      541 gggcttagaa attggatcat ctggattggt tatttcttca cgttcttccc gttatatgtc
      601 atcattatcc ttttgatatg tatattactc tttgtccagc tcgtttggct gcttctgctg
      661 gaaacctcct attttttgcc agtttctttc cctataattt catctctgaa tactatggga
      721 tgttgaacct tactaccaag ataaccgcct gtctgagtgc aaatgttgct ttggcactgg
      781 gaattaatat cttaatcaag ttggaaatac aagagattgg tgttaaatgg cacaaccttt
      841 ggacaccagc caatcttgag gataacctca actttggcta tatgcttgga atgcttttgt
      901 ttgatgcttt cttatacagc cttgttacct ggtatgtaga agccgtcttt cctggacagt
      961 gtggtgtgcc tcaaccatgg tactttttcc ttatgcgctc atattggttt ggcaaaccaa
     1021 aaattagaaa gactacagaa gaggcaaagt gcacccccat agtacataac tgctatgagg
     1081 ctgaacctcc caacttggag gcaggaatcc atatcatgca tttgcacaag gaatttaaaa
     1141 acaaacctgc agtaaacaac ttgtcactga acatatatga ggggcaggtc actgttcttc
     1201 tgggacacaa tggggcagga aagaccacaa ccctgtctgt tctcacaggt cgttttgctg
     1261 ctaccagagg agaggcctat attaatggat ataacatttc agataacatg attgaagtta
     1321 gaaaagactt gggtttctgc ccacaacacg acctattgtt tgacgatttg acattatcag
     1381 aacacctttt tttctactgt atggtaaaag gaatacctca aaacataaac tgtgaggaaa
     1441 ttgaccgtat gctgtcagct tttaacctgc aagaaaacta ccatacatta tcaggttcag
     1501 cgagtggagg agtgagacgc aaactctcta tcgttttagc acttatggcg ggctccaagg
     1561 tagtgatact tgatgagcca tcatccggca tggacccagt gtcaagaaga gccacctggg
     1621 atatccttca gcattataaa cacaatcgaa ccattttact gaccacccac tacatggatg
     1681 aagctgacgt cctgggtgac cgtgttgcca tcatggtcag gggcaccttg cactgctgtg
     1741 gctcttcagt cttcctgaaa caaatatatg gtgctggata tcacatcgtc atggagaagc
     1801 aacaatattg tgatgttgat aatatcattg caatgattca gcagcatgtt ccaggtgctg
     1861 tgttggaaaa taatatagaa aatgaattat catttatcct acccaaaaag tatgtatcaa
     1921 gatttgaaac tttgtttaca gagttagaaa tgagacaaaa agcactaggc attgccagct
     1981 ttggagcttc gatcactaca atggaagagg tttttgttaa ggtcaataag ctggcaactc
     2041 ctcaaaagag tattcaaact atccaaccat attacttggc atacagaaag atgagacaag
     2101 atgagcagca gaatgtgaat atgcccataa attatagcaa accaaatttt ccctatttga
     2161 gtgaaattgc tactgttaaa tttaacactg gggttccact ttaccgccag caattctatt
     2221 ccctgtttat aaaaagagca ctattcatta gccgcaactg gaagttcatg ctactgcaga
     2281 taatagtagt tatggttgtc actacatacc tcttattagc tctgcattta aataataatg
     2341 atatacctga aagggaactg aatttgagtc actatggtag aaccattgta ccttactcaa
     2401 cttcagggaa ttctgatttg gctctgaatc tcacaaagaa cctgaatatt tttctaaagt
     2461 caaaaaatca aaacttaaga aaaataagag gtgatatgaa tgattacata ttaaaaaata
     2521 aagattgtca caccttctgc cttgttgcac tttctattaa agttgagaga aataaaacag
     2581 tgctcactat tttcttcaat aatgaagcat accactcacc tgcaatatct ctgtcaatat
     2641 tagacaacat tctttttatg acactttctg gccctgatgc ttccattact gtcttcaata
     2701 agccgcaacc tctccctcat tacggttcga acatagtgcc tgtaaatgga ttgcaaatag
     2761 tacagtgttt agcttttggc atttctgtgg tggtcgggtc ctttagtatc cagacagtaa
     2821 ctgaaagaac cagccaagcc aagcacatcc agtttctgac tggagtctgt gtgcatactt
     2881 actggctctc tgccttgctg tgtgacctca tcttcttctt ctttgcctgc tgtgtactac
     2941 tggccatatt taaattctgc cagctggagg catttgtcgt gcattacaac ttcctggaca
     3001 caattctgat ctttatgctt tatggctggt gtgttgttcc tctcacttat attgcaagct
     3061 ttctgttcaa tagtagcact gctgcctaca tcaaaatcac gctctttaac tacttctcaa
     3121 ctatgttcag tatcatcatt tacactatca tacaatttta tggtaatgac tttcctaact
     3181 ttgtccacat cctcataagg gcaattttga tggcattgcc tagttacaac cttgcaatga
     3241 gtatcagcaa gtattttgat gactatgagg tgaaaagatt gtgtgctagg gaattcaaaa
     3301 gcatttactt ggattgcagt gacccataca ctcagaacaa cgtgtatggc tttggagagc
     3361 atgggattgg gaagtttcta atcacactgg ctaccattgg cttggttttt ctcctcttgc
     3421 ttttatcact ggagtctgtt tcctgtagtc tgaagagctt tgtctttcga aacattatct
     3481 tttatttcta caataagctc agaaaaggca ggaatgctat accatctaat cagagaacca
     3541 aagaagatga agatgaagac ataaaaaaag aaaaaggaaa agtcttcaca ctgctgctca
     3601 ggttacagaa caccccactg ctccttaatg aagttacaaa gatttatttt aagtgtcctg
     3661 ttgtcaaggc tgtgaaaaat atctcccttg tagtcaagaa gtcggagtgc tttggattgc
     3721 ttggattaaa cggagcagga aaaactacta cgttcaaaat gctgaccgga gaagagacta
     3781 tcacctccgg aattgcgttt attgatggca atagtgtcac tagaacccca agaaagatta
     3841 ggtcaagaat tggttactgt cctcagactg aatctgtgct gaaccacatg acaggccggg
     3901 aatcattggt catgtacgct aggttgtggg gcgtcctaga gcaagacatt aatgagtatg
     3961 tggaagcctt tctgcattca gtgcacctgg aacccattgc tgaccagttt atccacacgt
     4021 acagtgctgg aagcaaacgt aggctaagca ctgctatcgc cctaatggga aagtcttcag
     4081 ttgtcttcct ggatgaacca tctattggca tggacccagt agctcagcat ctgctctggg
     4141 aaacaattac atggatctgt aagactggta aagctatcat cataacttcc cacagaatgg
     4201 aagaatgtga ggccctgtgt actaggctgg ccatcatggt gaaagggagg tttacatgcc
     4261 taggcacccc ccagcatgtc agaaagaggt ttggtcatgt atacactcta acagtaagaa
     4321 tcaatattgc taaggatgaa gataaagtag aagagttcaa aaatttcatt aaagtaactt
     4381 tcccaggtaa catcaaattc caggaatttc atgggactat tggctactat attccaagca
     4441 aggaaatcta ctggggaaag gtatttgcaa ttttggagga agctaaagtg ctgttcaagt
     4501 tagaagacta ttctgtcaaa cgagtaaccc ttgaacaaat ctttctgacc ttcgctaata
     4561 ctgataaaat gagaacgtat caggaaataa agctgcagta agcttgcagt ccaacca
//
