LOCUS       NM_026661               3447 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus AAR2 splicing factor homolog (Aar2), transcript
            variant 2, mRNA.
ACCESSION   NM_026661
VERSION     NM_026661.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3447)
  AUTHORS   Cross,M., Nguyen,T., Bogdanoska,V., Reynolds,E. and Hamilton,J.A.
  TITLE     A proteomics strategy for the enrichment of receptor-associated
            complexes
  JOURNAL   Proteomics 5 (18), 4754-4763 (2005)
   PUBMED   16267818
REFERENCE   2  (bases 1 to 3447)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 3447)
  AUTHORS   Wertz,K. and Herrmann,B.G.
  TITLE     Large-scale screen for genes involved in gonad development
  JOURNAL   Mech Dev 98 (1-2), 51-70 (2000)
   PUBMED   11044607
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ152371.1, AK018741.1 and AK028890.1.
            
            On Sep 19, 2009 this sequence version replaced NM_026661.3.
            
            Transcript Variant: This variant (2) lacks an internal exon in the
            5' UTR, as compared to variant 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028890.1, AK018741.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                CJ152371.1         2-21
            21-2631             AK018741.1         2-2612
            2632-3447           AK028890.1         2610-3425
FEATURES             Location/Qualifiers
     source          1..3447
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 77.54 cM"
     gene            1..3447
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /note="AAR2 splicing factor homolog"
                     /db_xref="GeneID:68295"
                     /db_xref="MGI:MGI:1915545"
     exon            1..308
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            309..1109
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             353..1507
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /note="novel transcript"
                     /codon_start=1
                     /product="protein AAR2 homolog"
                     /protein_id="NP_080937.3"
                     /db_xref="CCDS:CCDS16967.1"
                     /db_xref="GeneID:68295"
                     /db_xref="MGI:MGI:1915545"
                     /translation="MSSMQMDPELAKQLFFEGATVVILNMPKGTEFGIDYNSWEVGPK
                     FRGVKMIPPGIHFLYYSSVDKANPREVGPRMGFFLSLKQRGLTVLRWNAVQEEVDLSP
                     APEAEVEAMRANLPDLDQFLGPYPYATLKKWISLTNFISEATMEKLQPESRQICAFSD
                     VLPVLFMKHTKDRVGQNLPLCGTECRSYQEGLARLPEMRPRAGTEIRFSELPTQMFPA
                     GATPAEITRHSMDLSYALETVLSKQFPGNPQDVLGELQFAFVCFLLGNVYEAFEHWKR
                     LLNLLCRSESAMGKYHALYISLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSS
                     ACSIAVEATLRKKAEKFQAHLTKKFRWDFTSEPEDCAPVVVELPEGIETA"
     exon            1110..1339
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..3447
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2609..2614
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2633
                     /gene="Aar2"
                     /gene_synonym="0610011L14Rik"
                     /note="major polyA site"
ORIGIN      
        1 agccgaactt ccgtcccgtt tccgcggaac cggagcttga ggtgctacgg tgagtgtcgg
       61 ccctcggtgc gcctttcggc ctccggtttc cttgtgtgtg gtcgggccac ctcgcttctt
      121 gtctcagaat cgcgctggcg gagtctggct ttgtgagctg gtgtctgagg aggcctttct
      181 tcctgagaac ccgtccctga ggacaccgtg gtcagggtct ctggggctcc cgaaggaact
      241 tccccccaca cccctttaac tgtaaccaga gaacgagact cactcgagct ggatctgcgt
      301 ggcttccgga gacagaaaag agccctgctt ttggttaccc tccactggct tcatgtcttc
      361 catgcagatg gatccagagt tagccaagca gctcttcttt gaaggagcca cggtggtcat
      421 tctgaacatg cccaagggga cagagtttgg cattgactac aactcttggg aggtggggcc
      481 caagttccgg ggtgtgaaga tgattccccc tggcatccac ttcctgtact acagctctgt
      541 ggacaaggcc aatcccaggg aggtgggccc tcgcatgggc ttcttcctca gcctgaagca
      601 gcgggggctg acagtcctgc gctggaatgc agtccaggaa gaagtagacc tgtctccagc
      661 tccagaggct gaagtagaag ctatgagagc caatctccca gacctagacc agtttctggg
      721 accttaccca tatgctacac tcaagaaatg gatctcactc accaacttca tcagtgaggc
      781 caccatggag aagctgcagc ctgagagcag gcagatctgc gccttctcag atgtgctgcc
      841 tgtgcttttc atgaagcaca ccaaggacag ggtggggcag aacctgcccc tctgcggcac
      901 cgagtgcaga agctaccaag agggcctagc ccggctgccc gagatgaggc ccagggctgg
      961 gacagagatc cgcttctcag agttgcccac tcagatgttc ccagcaggag ccacaccagc
     1021 agagatcacc aggcacagca tggacttgag ctatgccctc gaaactgtgc tcagcaagca
     1081 gttccctggc aacccccagg atgtgcttgg tgagctccag tttgcctttg tgtgcttctt
     1141 gctgggcaat gtgtatgagg catttgagca ctggaagcgg ctcctgaacc tcctgtgtcg
     1201 gtctgaatct gccatgggga agtaccacgc cctgtacatc agcctcatct ccatcctgta
     1261 ccaccagctt ggtgagatcc ctgctgactt ctttgtggac attgtctccc aggacaactt
     1321 cctcaccagt accttacagg ttttcttttc ttctgcctgc agtattgctg tggaagccac
     1381 cctgaggaag aaagctgaga agttccaagc ccacctgact aagaagttcc gctgggactt
     1441 cacttcagag ccagaggact gtgccccagt ggtggtggag ctccccgagg gcatcgagac
     1501 ggcctaactg caaatcctca agctgtggga gacctcttcc ctcatcacta caacccagcg
     1561 tctcccccat tcattgtcct ggaaccctgc agcacagtga tccagtcagg tcccgcaagg
     1621 atggagctgg agcctgtgct caccataata cgttcctttg ctacaaacgt ggccatttat
     1681 gtatggcttc ctatagactg gcccagccgc tgaatttcag gaaaaaaaga ggtcgagatg
     1741 aaacctgccc cagcaacagt ctaattcctt ctgacaatga gaaatgaaca ttagatccaa
     1801 aagaactagc tgcttattcc attgctgctt aaaagaggaa agaaaccaga tccatcctag
     1861 ggtctgtggc attaagtcag tgagttttta agttaagtgt gggttggtag ctgaatgtgg
     1921 tttgtataga gtttctgcct gctcctggtt ggatggaagg aaacctgctg gaactcaggc
     1981 cactgacctc tcaggagcct agctgggaac aggtgacaag gaagatgatg ggttgagtct
     2041 agcaggtggc cagcttcatc tgccacacct ccttctgcca aaagccacag tggttaatac
     2101 ctgagtcggc cgctgactgt ggggtctcct gctactgtca ccgtcatcct gaggcctcac
     2161 tctgcagcag gatgtagaaa cctcccacgg gttcccattt ctcacaaagg ctcccatgat
     2221 gcttctgatg acatggaaat caacagcaaa aggaggggtc ttgctctgag cctgcttctt
     2281 aagccctggt aaagcctggg cctttcttca gaaccataga gatagctggg tagcttaact
     2341 ctccccagca ctgctgtggg attctcatga gtgctgtcat gtttctggtg ttagggagtc
     2401 ttgaaggcac acccattgtg cggtgtgggc agagttctgc ctcaagaagg gctcccaggc
     2461 cctccattct gacctcaggc tctctgctgt actctggagt ccttctgagg cttgagctca
     2521 cagcaggcca gtgagtgaga gtcctgctgt ttaagacttt tggttcctct tgtttccttg
     2581 gagatgtttt tccaagagca caatgtacat taaagtcttt gagttgggac taatccccct
     2641 gtgtgagtct cttacagcta atctgcccag tttccaaagt agccaagctg tgtgcataga
     2701 caacacatct acctgcagaa cccaccctgg agacctgctc actccctaca gtccctggag
     2761 aaggcagcca gccagccagc tttgcctttt tgcagagaga cacaccctgt agctctacat
     2821 taacctcaag tttcaccttg tgggaattgc tattcctttt tccccacaaa acccactcat
     2881 cacaactacc tggggactgg gttaaaagtg catctcccaa caaatgaatt tctgatgcag
     2941 gctgcaatgt gtacaaacct tctgccgggg ctgaggaaat gactcaatgg gtaaactgct
     3001 tggtataaag cgtgaagacc ttcagatccc cagaactcgt gaaaggccag ggcagcagtg
     3061 cataccagta atcaaaatgc tgcagaggct gagtggtcct aggggctttc tggtaagctg
     3121 gaacttggta agctgcaggt tcagggagag accctgtctc ggacataagg tggaaagtga
     3181 cagaagacat ccagtatcaa cctctgacct ccacatgctc acacacaaat gcacctaaca
     3241 catataccac gcattcacta acagactgtg ttggggttag gaggccacac gacatgcagg
     3301 ctttccgctc acaggcaata cccagcatag gcagatccac atggtgacag atgaaggcca
     3361 cccacagcgt gccctcagaa gcagtggttt gtggtagaac acttgtcaaa ccatactcca
     3421 cgcagattta agagctgtag ttctgag
//
