LOCUS       NM_001177945             893 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus adipogenesis associated Mth938 domain containing
            (Aamdc), transcript variant 1, mRNA.
ACCESSION   NM_001177945
VERSION     NM_001177945.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Ma,X., Ding,W., Wang,J., Wu,G., Zhang,H., Yin,J., Zhou,L. and Li,D.
  TITLE     LOC66273 isoform 2, a novel protein highly expressed in white
            adipose tissue, induces adipogenesis in 3T3-L1 cells
  JOURNAL   J Nutr 142 (3), 448-455 (2012)
   PUBMED   22279136
REFERENCE   2  (bases 1 to 893)
  AUTHORS   Wang,H., Ma,X., Zhang,H., Zang,J., Hu,S. and Li,D.
  TITLE     Involvement of LOC66273 isoform 2, a novel Mth938 containing
            protein, in MAPK pathway
  JOURNAL   Front Biosci (Elite Ed) 3 (4), 1241-1248 (2011)
   PUBMED   21622130
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 893)
  AUTHORS   Kuninger,D., Kuzmickas,R., Peng,B., Pintar,J.E. and Rotwein,P.
  TITLE     Gene discovery by microarray: identification of novel genes induced
            during growth factor-mediated muscle cell survival and
            differentiation
  JOURNAL   Genomics 84 (5), 876-889 (2004)
   PUBMED   15475267
REFERENCE   4  (bases 1 to 893)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149605.7, BY259812.1, BC062811.1 and AW124043.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026557.1, BF682261.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AC149605.7         164868-164871       c
            5-45                BY259812.1         2-42
            46-386              BC062811.1         1-341
            387-482             AW124043.1         191-286             c
            483-884             BC062811.1         342-743
            885-893             AC149605.7         135705-135713       c
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 53.54 cM"
     gene            1..893
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /note="adipogenesis associated Mth938 domain containing"
                     /db_xref="GeneID:66273"
                     /db_xref="MGI:MGI:1913523"
     exon            1..132
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /inference="alignment:Splign:2.1.0"
     exon            133..236
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..623
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UPF0366 protein C11orf67 homolog; mth938 domain-containing
                     protein"
                     /codon_start=1
                     /product="mth938 domain-containing protein isoform 1"
                     /protein_id="NP_001171416.1"
                     /db_xref="CCDS:CCDS52316.1"
                     /db_xref="GeneID:66273"
                     /db_xref="MGI:MGI:1913523"
                     /translation="MYVRFPELLPTLLLTSQVLGSQISAQLLMASPKIASLSWGQMKV
                     QGSTLTYKDCKVWPGGSRAWDWRETGTEHSPGVQPADVKEVAEKGVQTLVIGRGMSEA
                     LKVPPSTVEYLEKQGIDVRVLQTEQAVKEYNALVAQGVRVGGVFHSTC"
     exon            237..386
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /inference="alignment:Splign:2.1.0"
     exon            387..482
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /inference="alignment:Splign:2.1.0"
     exon            483..893
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      858..863
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /note="hexamer: AATAAA"
     polyA_site      884
                     /gene="Aamdc"
                     /gene_synonym="1810020D17Rik; 1810037D19Rik; LI2"
                     /note="major polyA site"
ORIGIN      
        1 gggtgtgggc cggctgaagg cgaattccag gcctggtggc tgaaccgctg tggctcagag
       61 tccctcggct agctgcaggg aaaggtgaag cacggatccg actggaggaa caaccgcgaa
      121 cagaagcgct gcgcaaggta ccatgagtcc tggtttatcc ctaactgact atgtatgtga
      181 ggttccctga actcctcccg accctcctcc tcacctccca agtgctggga tcacagattt
      241 cagctcagtt acttatggct tcccctaaaa ttgcttccct ctcttgggga caaatgaaag
      301 tgcaaggctc taccttaacc tataaggatt gcaaagtatg gccaggaggc agtcgggctt
      361 gggactggag agaaacagga accgagcatt ctcctggagt gcagccagca gatgtaaagg
      421 aagttgctga gaaaggggta cagactcttg tgattggcag aggaatgagt gaggccttga
      481 aggtgcctcc gtcgactgtg gagtacctgg agaaacaagg cattgatgtg cgggtcctcc
      541 agacagagca ggccgtgaag gagtataatg ccttggttgc ccaaggggtc agggtaggag
      601 gtgtcttcca ttccacctgc tgatggcgcc tacagaggag aataaatcag accacaaagc
      661 cttggctgtc ttaccagtct ccacatcagc ctccactgtg tattttggac atatgttcat
      721 gttcttggga cagattggtg ggaggctgag gcacaggttt tgcactccag gttgcttaaa
      781 tcagagaaga gagaggtttg ctgacattta atattgtgct atgtgttagg ttcaaagttt
      841 gagaaacttg atacaaaaat aaaggttgaa acttgaaggc caaagagaaa gtt
//
