LOCUS       NM_001033220            1364 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus expressed sequence AU021092 (AU021092), transcript
            variant 1, mRNA.
ACCESSION   NM_001033220 XM_155973 XM_358755
VERSION     NM_001033220.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1364)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1364)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1364)
  AUTHORS   Afink,G.B., Veenboer,G., de Randamie,J., Keijser,R., Meischl,C.,
            Niessen,H. and Ris-Stalpers,C.
  TITLE     Initial characterization of C16orf89, a novel thyroid-specific gene
  JOURNAL   Thyroid 20 (7), 811-821 (2010)
   PUBMED   20578903
REFERENCE   5  (bases 1 to 1364)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124576.4.
            
            On Feb 27, 2023 this sequence version replaced NM_001033220.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK140126.1, BC171979.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AC124576.4         78713-78941
            230-379             AC124576.4         80559-80708
            380-530             AC124576.4         83056-83206
            531-648             AC124576.4         84145-84262
            649-784             AC124576.4         84892-85027
            785-889             AC124576.4         86297-86401
            890-970             AC124576.4         88332-88412
            971-1364            AC124576.4         88792-89185
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 2.51 cM"
     gene            1..1364
                     /gene="AU021092"
                     /note="expressed sequence AU021092"
                     /db_xref="GeneID:239691"
                     /db_xref="MGI:MGI:2146559"
     exon            1..229
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1191
                     /gene="AU021092"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; UPF0764 protein C16orf89 homolog"
                     /codon_start=1
                     /product="UPF0764 protein C16orf89 homolog isoform 1
                     precursor"
                     /protein_id="NP_001028392.2"
                     /db_xref="CCDS:CCDS27934.1"
                     /db_xref="GeneID:239691"
                     /db_xref="MGI:MGI:2146559"
                     /translation="MARLGLLLLLLLALPPHFSSVSWPDTAQGTMANLILTALEKATL
                     FLEDRLPTINLDGVVGFQVLEVQLRGVQEKWAHKPLLQPLSMRAGQMANTLSALLQKS
                     IFYLKQSDPTYLREFQPSIQPGFWKLPNDWTRTNASLVYPWLEPLDSFSEESSDVCLV
                     QLLGTGTDSSQPCRLSNFCRTLMTKAGCSGYSLSHQLLFFLWARMQGCTEGLFLQSQH
                     YMDIFCANMMELNHRAEAVGYAYPTQDLFMENIMFCGMAGFSDFYKLRWLEAILSWQN
                     PQVGCFGRPDTKGEPSEVPHQQGILRRVRRREKLFADGCSCHNTATAVAALGGFLYIL
                     AEYHPDNGDAHPEYYPNHGDPYSSSQSPASNYQDGAAGPDVQRTGRPLSVS"
     exon            230..379
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     exon            380..530
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     exon            531..648
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     exon            649..784
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     exon            785..889
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     exon            890..970
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1364
                     /gene="AU021092"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1340..1345
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AU021092"
                     /note="hexamer: AATACA"
     polyA_site      1364
                     /gene="AU021092"
                     /note="major polyA site"
ORIGIN      
        1 agggtgtggc catccaccag cagaaatcct gtcatggcga gactcgggct gcttctcctc
       61 ctgctgctgg ccctgccacc acacttctcc tcagtgtcat ggccagacac tgcacagggc
      121 accatggcaa acttgatcct gactgcatta gaaaaagcca ccttgttctt ggaggacagg
      181 ctgcccacaa tcaacctgga tggtgtggtg ggcttccaag tgctggaagt gcaactccga
      241 ggagttcagg aaaaatgggc tcacaagccc ttgctgcagc ctctcagcat gcgcgctgga
      301 cagatggcca acacactgtc tgctctcctc caaaaatcca tcttctacct caagcagagt
      361 gaccccacgt acctaagaga gttccagcca agcattcagc ctgggttttg gaagttgccc
      421 aatgactgga cacgcaccaa tgcctcccta gtctacccct ggctggaacc cctggactct
      481 ttctcagagg aaagcagcga tgtgtgcctg gtgcaactac taggaacagg gacagacagc
      541 agccagcctt gcaggctctc caacttctgc agaaccctta tgaccaaggc cggctgctca
      601 ggctacagcc tctcccatca gctgctcttc ttcctctggg ccagaatgca agggtgcacg
      661 gagggactgt tcctccagag ccaacactac atggacatct tctgtgccaa tatgatggaa
      721 ctgaaccaca gagctgaggc cgttggatac gcttacccca cccaagacct cttcatggaa
      781 aacattatgt tctgtggtat ggctggcttc tctgacttct acaagctgcg ctggctggag
      841 gccattctca gctggcagaa cccccaggtg ggatgcttcg ggaggcctga cacaaagggt
      901 gaaccttctg aagttccaca tcagcagggc attctgagaa gagtgcgaag gcgggaaaaa
      961 ctgttcgcag atggctgttc gtgccacaac acagccacag cagtcgcagc cctgggtggc
     1021 tttctctaca tcctggcaga ataccaccca gacaatggag atgcacatcc agaatactac
     1081 ccaaaccatg gagatccata ctcatcctca cagtcaccag caagcaacta ccaagatggt
     1141 gctgccggcc ctgacgtcca gaggactggc aggcccctta gtgtttctta agtcctgagt
     1201 cagaggtcac aggctgagga ggcaattgag gaaagtgacc agctatatcc ccatcgccac
     1261 ttctgggtgt ttaaaagtct tgggagagca gggccaggga aagcagggtt ggagagtggg
     1321 gtggcccaga tgtcagcaga atacataaag cacagtcaat tgga
//
