LOCUS       NM_134149               1539 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus expressed sequence AI837181 (AI837181), transcript
            variant 1, mRNA.
ACCESSION   NM_134149
VERSION     NM_134149.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1539)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 1539)
  AUTHORS   Bitto,E., Bingman,C.A., Robinson,H., Allard,S.T., Wesenberg,G.E.
            and Phillips,G.N. Jr.
  TITLE     The structure at 2.5 A resolution of human basophilic
            leukemia-expressed protein BLES03
  JOURNAL   Acta Crystallogr Sect F Struct Biol Cryst Commun 61 (Pt 9), 812-817
            (2005)
   PUBMED   16511166
  REMARK    GeneRIF: Structural characterization of the human ortholog.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ181010.1, BC017542.1 and AV579065.1.
            
            On Oct 3, 2008 this sequence version replaced NM_134149.1.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.415603.1,
                                           SRR1660817.407667.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                CJ181010.1         2-96
            96-119              CJ181010.1         100-123
            120-1508            BC017542.1         1-1389
            1509-1539           AV579065.1         426-456
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.32 cM"
     gene            1..1539
                     /gene="AI837181"
                     /gene_synonym="Bles03"
                     /note="expressed sequence AI837181"
                     /db_xref="GeneID:107242"
                     /db_xref="MGI:MGI:2147598"
     exon            1..165
                     /gene="AI837181"
                     /gene_synonym="Bles03"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..922
                     /gene="AI837181"
                     /gene_synonym="Bles03"
                     /note="isoform a is encoded by transcript variant 1;
                     basophilic leukemia expressed protein; protein WF-3;
                     basophilic leukemia-expressed protein Bles03; UPF0696
                     protein C11orf68 homolog"
                     /codon_start=1
                     /product="UPF0696 protein C11orf68 homolog isoform a"
                     /protein_id="NP_598910.2"
                     /db_xref="CCDS:CCDS29463.2"
                     /db_xref="GeneID:107242"
                     /db_xref="MGI:MGI:2147598"
                     /translation="MAAAAAAVAGAGRGGGGGGGGGGAADPGQERSRARSWVGAERSE
                     GRRMEPNEELEEEDSPGGREDGFTAEHLAAEAMAADMDPWLVFDARTTPATELDAWLA
                     KYPPSQVTRYGDPGSPNSEPVGWIAAYGQGYTPNSGDVQGLQAAWEALQTSGRPITPG
                     TLRQLAITHHVLSGKWLIHLSPGFKLDHAWAGIARAVVEGRLQVAKVSPRAKEGGRQV
                     ICVYTDDFTDRLGVLEADSAIRAAGIKCLLTYKPDVYTYLGIYRANRWHLCPTLYESR
                     FQLGGNTRGSRVLDRANNVELT"
     exon            166..1532
                     /gene="AI837181"
                     /gene_synonym="Bles03"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1489..1494
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AI837181"
                     /gene_synonym="Bles03"
                     /note="hexamer: AATAAA"
     polyA_site      1532
                     /gene="AI837181"
                     /gene_synonym="Bles03"
                     /note="major polyA site"
ORIGIN      
        1 gttgttgagg tggcgggacc ctaagatggc ggcggcggcg gcggccgtgg caggggcggg
       61 gcgcggcggg ggtggcggcg gcggcggcgg cggcgcagca gatcccgggc aggaacggag
      121 ccgggcccga agttgggttg gcgcggaacg gagtgaaggc cggaggatgg aaccaaatga
      181 ggagctggaa gaggaagact ctccaggtgg ccgggaggat ggcttcactg ctgagcacct
      241 ggctgcagag gccatggcag ccgatatgga cccctggctg gtatttgatg cccgtaccac
      301 acctgccaca gagctggatg cctggttggc caagtaccca ccatctcaag ttactcgcta
      361 tggggaccca ggttcaccca actctgaacc tgtgggctgg attgcagcct atgggcaggg
      421 ttacaccccc aactcagggg atgtacaagg gctgcaggcg gcctgggagg ctctgcagac
      481 cagtgggcga cccatcacac caggtaccct gcgccagctg gccatcaccc accatgtgct
      541 ctccggcaag tggctgattc acctgtcacc tggcttcaag ctggaccacg cctgggctgg
      601 cattgcccgg gctgtagttg agggccgtct ccaggtggcc aaggtgagcc cacgggccaa
      661 agagggtggg cgccaggtca tctgtgttta cacggacgac ttcacggacc gcttgggtgt
      721 gctggaagca gattctgcca ttcgtgctgc aggcattaag tgcttgctca cttacaaacc
      781 tgatgtctac acctacctgg gcatctaccg agccaaccgc tggcaccttt gccccactct
      841 ctatgagagc cgtttccagc ttggaggcaa tacccgtggc tctcgagtgc tggaccgtgc
      901 caacaatgta gaactgacct aatggggccg agcaggagag accacctttt gcttggatcc
      961 ttccttcttc tcttccttgt cccaagaagg ctgagctcct tagccctgag gactcattgg
     1021 cgtgggaact gcctgcactc agtccctttg cacttctgct ctctttgtgc agggccaact
     1081 cccaccctca caggttgggg gctctggctc ttggagggcg gggccctcgg cggccctctt
     1141 tgatgctgct ccccaccact gcccaggacc acagcttggg tgcagagact cgaggaagtc
     1201 tgtcctggcc acctctgtcc ccactatact tagcctgcat tcttcctttt ctttcctccc
     1261 tcagaaggga gaaaacttag tgcttccagc ccctgccctt ggcgccatca tagtccaggt
     1321 ggccgggccc ttccaggact aagcatgcta ttgggacctg tacatgttct ggccaagagg
     1381 agacgcaggg tcatggacat ggggtctgct cctccctgca aactcatagc ctgcatcacc
     1441 accacccctt ccctggctac cttgacatgt gcctgctcct gacatttcaa taaaacccag
     1501 ctcgggtctg tgtcttgagt gttttttaca aaaaaaaaa
//
