LOCUS       NM_001379434            1435 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus expressed sequence AI182371 (AI182371), transcript
            variant 4, mRNA.
ACCESSION   NM_001379434 XM_017319350
VERSION     NM_001379434.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1435)
  AUTHORS   Sottrup-Jensen L.
  TITLE     Alpha-macroglobulins: structure, shape, and mechanism of proteinase
            complex formation
  JOURNAL   J Biol Chem 264 (20), 11539-11542 (1989)
   PUBMED   2473064
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845534.7.
            
            On Apr 2, 2020 this sequence version replaced XM_017319350.2.
            
            Transcript Variant: This variant (4) encodes the longest isoform
            (4).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189682.9725.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: downstream AUG is associated
                                                with N-terminal localization
                                                signal
            RefSeq Select criteria           :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               AL845534.7         134021-134141       c
            122-317             AL845534.7         131344-131539       c
            318-480             AL845534.7         129217-129379       c
            481-551             AL845534.7         122595-122665       c
            552-643             AL845534.7         122196-122287       c
            644-726             AL845534.7         119887-119969       c
            727-789             AL845534.7         119557-119619       c
            790-852             AL845534.7         119160-119222       c
            853-1050            AL845534.7         118627-118824       c
            1051-1435           AL845534.7         117794-118178       c
FEATURES             Location/Qualifiers
     source          1..1435
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 23.34 cM"
     gene            1..1435
                     /gene="AI182371"
                     /note="expressed sequence AI182371"
                     /db_xref="GeneID:98870"
                     /db_xref="MGI:MGI:2138853"
     exon            1..121
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1106
                     /gene="AI182371"
                     /note="isoform 4 precursor is encoded by transcript
                     variant 4"
                     /codon_start=1
                     /product="hemolytic complement-like isoform 4 precursor"
                     /protein_id="NP_001366363.1"
                     /db_xref="GeneID:98870"
                     /db_xref="MGI:MGI:2138853"
                     /translation="MVLIPSQAMGFWGTLLFLIFLEQSWGQEQTRYIISTPIVFRVGA
                     PENVTVQAHGHTEAFDTTVSVKSYPDENVRYSFSTVNLSPENKFQNTAILTIQAKQLS
                     EGQNSFSNSYLEVVSKHFAKLEIVPIIYDNDSLFVQTDKSVYTPQQPVKVRVYSVNDD
                     LEPATRETVLTFIDPEGSQVDTIEGNNLTGIASFPDFEIPSNPKHGRWTVKAKYREDA
                     SKTGTTYFEVKEYDKTYRISIMPTIDLQPEVEKQEAHGMCLHQPTECLRQKINEQAST
                     YKHPMIKKCCYDGARYNIHETCVQRAARVKIGPICVKAFTLCCNMAHQILENSTFKHI
                     HLSSHSNHQAEHGDPQWRSQGKD"
     exon            122..317
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            318..480
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            481..551
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            552..643
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            644..726
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            727..789
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            790..852
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1050
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1435
                     /gene="AI182371"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acatgcaaag tagcctcaaa gaggtgacag atatggtttt gataccgtct caagctatgg
       61 gcttttgggg aacacttctg tttctgatct tccttgaaca aagttgggga caggaacaaa
      121 ccagatacat catttcaacc ccaattgtct tccgagttgg agctcctgaa aatgttacag
      181 tccaagccca cggccatact gaggcatttg acacaactgt ctctgtaaaa agttatcctg
      241 atgaaaatgt tcgttactct ttcagcactg ttaatttatc accagaaaat aaattccaaa
      301 acactgcaat cttaacaatt caggccaaac agttatctga aggacaaaac tcattttcaa
      361 attcgtattt agaagtcgtg tcaaagcatt ttgcaaaatt agaaatcgtg ccaatcatct
      421 atgacaatga ctctctcttc gttcaaaccg acaagtccgt gtatactcca caacagcctg
      481 taaaggttcg tgtctactct gtgaatgatg acttagagcc ggccaccaga gaaacagtct
      541 taactttcat agatcctgaa gggtcccaag ttgacacaat agagggaaat aatctcaccg
      601 ggattgcctc ttttcctgac ttcgagattc cttctaatcc caagcacggt agatggacag
      661 tcaaggctaa gtatagagaa gatgcttcaa aaactggaac tacatacttt gaagttaaag
      721 aatacgataa aacttacaga atatctatca tgcccacaat tgatctgcaa cccgaggtgg
      781 aaaagcaaga agcacatggc atgtgtcttc atcagccaac agagtgtctg cgacagaaga
      841 taaacgagca agcttctaca tacaaacatc caatgataaa aaaatgctgt tacgatgggg
      901 ccagatataa catacatgag acctgtgtgc agcgagctgc ccgtgtgaag ataggcccga
      961 tctgtgtcaa agccttcact ctctgctgta acatggcaca ccagatccta gaaaacagca
     1021 cctttaagca catccatctg tcaagtcact ccaaccatca ggcagagcac ggggaccccc
     1081 aatggaggag tcaggggaag gactgaagga tctgcagggg tttgcaaacc ccataggaag
     1141 gaaagccgtt ttcatgtcct tgttgcaact aagagttgga aggcagacga cttgtaacgc
     1201 ccagatgaaa gtctgttgtt tttctcggta actggaaaca ctatagcacc cagcagacaa
     1261 cacctgtcca gagtcaaggc cccaggaaac cataggcagc tcgttatgca gactggaaat
     1321 ggcctccgga tgacaaagtg ccatgattct gtcacagtca ctaaaagctg aaatctttct
     1381 gtgtcagcct tactagatgt ttcagaatta aaggactttc ttaatattct caaaa
//
