LOCUS       NM_001198794            1295 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus cDNA sequence AB124611 (AB124611), transcript variant
            1, mRNA.
ACCESSION   NM_001198794
VERSION     NM_001198794.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1295)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1295)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1295)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1295)
  AUTHORS   Phillips,R.L., Ernst,R.E., Brunk,B., Ivanova,N., Mahan,M.A.,
            Deanehan,J.K., Moore,K.A., Overton,G.C. and Lemischka,I.R.
  TITLE     The genetic program of hematopoietic stem cells
  JOURNAL   Science 288 (5471), 1635-1640 (2000)
   PUBMED   10834841
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163748.6.
            
            On Aug 9, 2021 this sequence version replaced NM_001198794.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer protein (isoform 1).
            
            CCDS Note: The coding region has been updated to start at an
            alternate, downstream, in-frame start codon that is supported by
            conservation data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK170200.1, AK154442.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               AC163748.6         147220-147336
            118-438             AC163748.6         149792-150112
            439-528             AC163748.6         156937-157026
            529-556             AC163748.6         160116-160143
            557-600             AC163748.6         160871-160914
            601-638             AC163748.6         161615-161652
            639-1295            AC163748.6         165706-166362
FEATURES             Location/Qualifiers
     source          1..1295
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 7.82 cM"
     gene            1..1295
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /note="cDNA sequence AB124611"
                     /db_xref="GeneID:382062"
                     /db_xref="MGI:MGI:3043001"
     exon            1..117
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..755
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; HIDE1; protein HIDE1; highly expressed in
                     immature dendritic cell transcript 1 protein"
                     /codon_start=1
                     /product="protein HIDE1 isoform 1 precursor"
                     /protein_id="NP_001185723.2"
                     /db_xref="CCDS:CCDS57661.1"
                     /db_xref="GeneID:382062"
                     /db_xref="MGI:MGI:3043001"
                     /translation="MPWTILLFASGSLAIPAPSISLVPPYPSSHEDPIYISCTAPGDI
                     LGANFTLFRGGEVVQLLQAPSDRPDVTFNVTGGGSGGGGEAAGGNFCCQYGVMGEHSQ
                     PQLSDFSQQVQVSFPVPTWILALSLSLAGAVLFSGLVAITVLVRKAKAKNLQKQRERE
                     SCWAQINFTNTDMSFDNSLFAISTKMTQEDSVATLDSGPRKRPTSASSSPEPPEFSTF
                     RACQ"
     exon            118..438
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /inference="alignment:Splign:2.1.0"
     exon            439..528
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /inference="alignment:Splign:2.1.0"
     exon            529..556
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /inference="alignment:Splign:2.1.0"
     exon            557..600
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /inference="alignment:Splign:2.1.0"
     exon            601..638
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /inference="alignment:Splign:2.1.0"
     exon            639..1295
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1270..1275
                     /regulatory_class="polyA_signal_sequence"
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /note="hexamer: ATTAAA"
     polyA_site      1295
                     /gene="AB124611"
                     /gene_synonym="Gm1706"
                     /note="major polyA site"
ORIGIN      
        1 ctttctccgc tgtggtctcg ggctggcagg gagccccaga tccccgtggc cttggccagc
       61 tttcccagcc ctacatggga ggagagatgc cctggaccat cctgctgttt gcatctggct
      121 ccttggccat ccctgcacca tccatctcct tggtgccccc ctacccaagc agccacgagg
      181 accccatcta catctcgtgc acagccccag gggacatcct aggggccaat tttaccctgt
      241 tccgaggggg agaggtggtc cagctactac aggccccctc agatcggcct gatgtaacat
      301 tcaatgtgac tggtggtggc agtggtggtg gcggtgaggc tgctgggggg aacttctgct
      361 gtcaatatgg tgtgatgggt gagcacagtc agccccagct gtcggacttc agccagcagg
      421 tgcaggtctc cttcccagtc cccacctgga tcttggcact ctccctgagc ctggctggag
      481 ctgtgctgtt ctcagggctg gtggccatca cagtgctggt gagaaaagct aaagccaaaa
      541 acttacagaa gcagagagag cgtgaatcct gctgggctca gatcaacttc accaatacag
      601 acatgtcctt tgataactct ctgtttgcta tctccacgaa aatgactcag gaagactcag
      661 tggcaaccct agactcaggg cctcggaaga ggcccacctc tgcatcatcc tctccggagc
      721 cccctgagtt cagcactttc cgggcctgcc agtgaggctg acgaatgagg accactttat
      781 ccagttcctt ccctcccact gccagaggct gcacatctgt ccagagactt ggcagtggag
      841 gtagggtggg ggtgggaatc aagccatagc tttcttaggg aagcactggc caaaggaagg
      901 ggactcctag agttgtaacc ttcctcacag aagacaagaa aatgagttgg ggtatcagcc
      961 tcaggctaga cagagagcca gaacctcttc acagattccc agatcaccgg agaagtcact
     1021 attgaatccg gacacccagt caggcacaag aggtctacat tctctaactc ctttccagtg
     1081 cttccccaac ggtcacttac ttccagactg cgtgttttat ttttaggaga gatgtgtata
     1141 ttttttgttg ctgttgttgt ttctagatag ggtctcactg tgtagccctg gcttttctgg
     1201 aactcactgt gtagagcaag ccagcctcaa actcatagat ccacctgcct ctgcctccag
     1261 atcgctagaa ttaaagttac tgccataaca cctaa
//
