LOCUS       NM_001004174             640 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus expressed sequence AA467197 (AA467197), mRNA.
ACCESSION   NM_001004174 XM_485059
VERSION     NM_001004174.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Xiong,M., Liu,Z., Wang,B., Sokolich,T., Graham,N., Chen,M.,
            Wang,W.L. and Boldin,M.P.
  TITLE     The epithelial C15ORF48/miR-147-NDUFA4 axis is an essential
            regulator of gut inflammation, energy metabolism, and the
            microbiome
  JOURNAL   Proc Natl Acad Sci U S A 121 (27), e2315944121 (2024)
   PUBMED   38917002
  REMARK    GeneRIF: The epithelial C15ORF48/miR-147-NDUFA4 axis is an
            essential regulator of gut inflammation, energy metabolism, and the
            microbiome.
REFERENCE   2  (bases 1 to 640)
  AUTHORS   Takakura,Y., Machida,M., Terada,N., Katsumi,Y., Kawamura,S.,
            Horie,K., Miyauchi,M., Ishikawa,T., Akiyama,N., Seki,T., Miyao,T.,
            Hayama,M., Endo,R., Ishii,H., Maruyama,Y., Hagiwara,N.,
            Kobayashi,T.J., Yamaguchi,N., Takano,H., Akiyama,T. and
            Yamaguchi,N.
  TITLE     Mitochondrial protein C15ORF48 is a stress-independent inducer of
            autophagy that regulates oxidative stress and autoimmunity
  JOURNAL   Nat Commun 15 (1), 953 (2024)
   PUBMED   38296961
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 640)
  AUTHORS   Hamley,M., Leyk,S., Casar,C., Liebold,I., Jawazneh,A.A.,
            Lanzloth,C., Bottcher,M., Haas,H., Richardt,U., Rothlin,C.V.,
            Jacobs,T., Huber,S., Adlung,L., Pelczar,P., Henao-Mejia,J. and
            Bosurgi,L.
  TITLE     Nmes1 is a novel regulator of mucosal response influencing
            intestinal healing potential
  JOURNAL   Eur J Immunol 54 (2), e2350434 (2024)
   PUBMED   37971166
  REMARK    GeneRIF: Nmes1 is a novel regulator of mucosal response influencing
            intestinal healing potential.
REFERENCE   4  (bases 1 to 640)
  AUTHORS   Endou,M., Yoshida,K., Hirota,M., Nakajima,C., Sakaguchi,A.,
            Komatsubara,N. and Kurihara,Y.
  TITLE     Coxfa4l3, a novel mitochondrial electron transport chain Complex 4
            subunit protein, switches from Coxfa4 during spermatogenesis
  JOURNAL   Mitochondrion 52, 1-7 (2020)
   PUBMED   32045714
  REMARK    GeneRIF: Coxfa4l3, a novel mitochondrial electron transport chain
            Complex 4 subunit protein, switches from Coxfa4 during
            spermatogenesis.
REFERENCE   5  (bases 1 to 640)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   6  (bases 1 to 640)
  AUTHORS   Kozomara,A. and Griffiths-Jones,S.
  TITLE     miRBase: integrating microRNA annotation and deep-sequencing data
  JOURNAL   Nucleic Acids Res 39 (Database issue), D152-D157 (2011)
   PUBMED   21037258
REFERENCE   7  (bases 1 to 640)
  AUTHORS   Liu,G., Friggeri,A., Yang,Y., Park,Y.J., Tsuruta,Y. and Abraham,E.
  TITLE     miR-147, a microRNA that is induced upon Toll-like receptor
            stimulation, regulates murine macrophage inflammatory responses
  JOURNAL   Proc Natl Acad Sci U S A 106 (37), 15819-15824 (2009)
   PUBMED   19721002
REFERENCE   8  (bases 1 to 640)
  AUTHORS   Arai,M., Imazeki,F., Sakai,Y., Mikata,R., Tada,M., Seki,N.,
            Shimada,H., Ochiai,T. and Yokosuka,O.
  TITLE     Analysis of the methylation status of genes up-regulated by the
            demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous
            cell carcinoma
  JOURNAL   Oncol Rep 20 (2), 405-412 (2008)
   PUBMED   18636205
REFERENCE   9  (bases 1 to 640)
  AUTHORS   Zhou,J., Wang,H., Lu,A., Hu,G., Luo,A., Ding,F., Zhang,J., Wang,X.,
            Wu,M. and Liu,Z.
  TITLE     A novel gene, NMES1, downregulated in human esophageal squamous
            cell carcinoma
  JOURNAL   Int J Cancer 101 (4), 311-316 (2002)
   PUBMED   12209954
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772253.12.
            
            On Aug 29, 2018 this sequence version replaced NM_001004174.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049633.1, CA465863.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AL772253.12        73583-73637
            56-117              AL772253.12        73768-73829
            118-203             AL772253.12        73953-74038
            204-264             AL772253.12        74912-74972
            265-640             AL772253.12        76397-76772
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.64 cM"
     gene            1..640
                     /gene="AA467197"
                     /gene_synonym="mir-147; Nmes1"
                     /note="expressed sequence AA467197"
                     /db_xref="GeneID:433470"
                     /db_xref="MGI:MGI:3034182"
     exon            1..55
                     /gene="AA467197"
                     /gene_synonym="mir-147; Nmes1"
                     /inference="alignment:Splign:2.1.0"
     exon            56..117
                     /gene="AA467197"
                     /gene_synonym="mir-147; Nmes1"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..333
                     /gene="AA467197"
                     /gene_synonym="mir-147; Nmes1"
                     /note="normal mucosa of esophagus specific 1"
                     /codon_start=1
                     /product="normal mucosa of esophagus-specific gene 1
                     protein"
                     /protein_id="NP_001004174.1"
                     /db_xref="CCDS:CCDS38224.1"
                     /db_xref="GeneID:433470"
                     /db_xref="MGI:MGI:3034182"
                     /translation="MGVFQILMKNKELIPLAFFISVAATGATSFALYALKKTDVVIDR
                     KRNPEPWEMVDPTQPQKLITINQQWKPVEELQKVRRATR"
     exon            118..203
                     /gene="AA467197"
                     /gene_synonym="mir-147; Nmes1"
                     /inference="alignment:Splign:2.1.0"
     exon            204..264
                     /gene="AA467197"
                     /gene_synonym="mir-147; Nmes1"
                     /inference="alignment:Splign:2.1.0"
     exon            265..640
                     /gene="AA467197"
                     /gene_synonym="mir-147; Nmes1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atataagggc cgctcgcttc tgggcgttaa catctcctgg ccgcagccgc cctagatttg
       61 gaattctaca ctaaagtcat catgggcgtt ttccagatat tgatgaagaa taaggaactc
      121 attcctttgg cgttttttat aagcgtggcc gccaccggag ccacatcttt cgctttgtat
      181 gcgttgaaaa aaaccgacgt ggttattgat cggaaaagaa acccagagcc ttgggaaatg
      241 gtggatccta ctcaacccca aaagcttata accatcaacc agcaatggaa gcccgttgag
      301 gagctgcaaa aagtccggag ggcaaccaga tgattgctca ccactcctct cttccaaaga
      361 acactctatg aatctagtgg aaacatttct gcacaaacta gatgttgatg ccagtgtgcg
      421 gaaatgcttc tgctacattt gtagggtttg cctgcattct ttggatcctg cattagcaag
      481 tgaaggtagc acatagtcta aaatagtttt ctgtgtttat tggtgtaaat ttcaatttta
      541 cagttgaaat tttatgtttg tgatgcttgg atattttcct tgaaatgtat aaacatgtaa
      601 aaattagatt actgcctgta ataaaataat tcgatgacta
//
