LOCUS       NM_178796               1900 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus RIKEN cDNA A530064D06 gene (A530064D06Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_178796
VERSION     NM_178796.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1900)
  AUTHORS   Watarai H, Sekine E, Inoue S, Nakagawa R, Kaisho T and Taniguchi M.
  TITLE     PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is
            responsible for augmented production of type I interferon
  JOURNAL   Proc Natl Acad Sci U S A 105 (8), 2993-2998 (2008)
   PUBMED   18287072
  REMARK    GeneRIF: PDC-TREM is responsible for IFN-alpha production in
            plasmacytoid dendritic cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY194994.1, AK080114.1 and AK171433.1.
            
            On Jan 17, 2008 this sequence version replaced NM_178796.5.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK080114.1, EU003111.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                BY194994.1         46-85
            41-1897             AK080114.1         2-1858
            1898-1900           AK171433.1         1675-1677
FEATURES             Location/Qualifiers
     source          1..1900
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 23.99 cM"
     gene            1..1900
                     /gene="A530064D06Rik"
                     /gene_synonym="pdctrem; Trem4"
                     /note="RIKEN cDNA A530064D06 gene"
                     /db_xref="GeneID:328830"
                     /db_xref="MGI:MGI:2443476"
     exon            1..327
                     /gene="A530064D06Rik"
                     /gene_synonym="pdctrem; Trem4"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..959
                     /gene="A530064D06Rik"
                     /gene_synonym="pdctrem; Trem4"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; plasmacytoid dendritic cell-specific receptor;
                     triggering receptor expressed in myeloid cells 4;
                     triggering receptor expressed on myeloid cells 4"
                     /codon_start=1
                     /product="triggering receptor expressed in myeloid cells 4
                     isoform a precursor"
                     /protein_id="NP_848911.2"
                     /db_xref="CCDS:CCDS28859.1"
                     /db_xref="GeneID:328830"
                     /db_xref="MGI:MGI:2443476"
                     /translation="MAWEPTYLLSPVLLLLLASGSWTQNPELLRTQEGETVSVTCWYD
                     SLYHSSEKIWCKQIDNLCYPFVSKSAEKPRFLIQQSSRFNFFTVTMTKLKMSDSGIYH
                     CGIVANNTSVYLRNIHLVVSKGSSVVSTPDIIPATRLTKLPTLITTKHSPSDTTTTRS
                     LPQPTTVVSSPDPRVIIINGTDADRGFVSSVTIPVVCGLLSKTLVFTVLFIVTQKSFG
                     RQAMKAHNSNS"
     exon            328..639
                     /gene="A530064D06Rik"
                     /gene_synonym="pdctrem; Trem4"
                     /inference="alignment:Splign:2.1.0"
     exon            640..823
                     /gene="A530064D06Rik"
                     /gene_synonym="pdctrem; Trem4"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1900
                     /gene="A530064D06Rik"
                     /gene_synonym="pdctrem; Trem4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1880..1885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="A530064D06Rik"
                     /gene_synonym="pdctrem; Trem4"
                     /note="putative"
ORIGIN      
        1 ctcagctctc ctcaggcctg gccttgtgag gcaggagatc agagtctctg agagctttca
       61 tctagttcag agcaaggctg tagctggagg atccacagga ctgcacagac cttgcccagc
      121 ttctctctca tccacagagg tctctgcctt cctcgggagc tcctgcagaa ctggctgtgg
      181 tggctcctga atcctgccca gggttgctct cctctcttca gagctcccct cctttcttgc
      241 tcaacatcac agctcaggag gactcagtga tggcctggga gcccacatac ctgctctccc
      301 cagtgctgct gctgctcctg gcctcaggct cctggacaca gaacccggag ttacttcgaa
      361 cacaggaggg tgagactgtt tctgtgacat gctggtatga ttcgctctac cactccagcg
      421 agaagatctg gtgtaagcaa atagacaact tgtgttaccc cttcgtcagc aaaagtgccg
      481 agaagccaag attcctcatc cagcagtctt ctcgcttcaa cttcttcact gtcaccatga
      541 ctaagctcaa gatgagtgac tcgggcatct atcactgtgg gattgttgca aataacacgt
      601 cagtttatct cagaaatatc cacctggtgg tgtcaaaagg ttcttcagtt gtgtccactc
      661 ctgacatcat tcctgctaca aggctaacta agcttcctac ccttattacc acaaaacact
      721 cacccagtga cacaactaca acccgatctc taccccagcc caccactgtt gtttcctctc
      781 ctgatcctag agtcatcatc ataaatggga cagatgctga caggggcttt gtatccagtg
      841 ttactattcc cgtggtctgt ggactcctca gcaagacact ggtattcacg gtcttattca
      901 ttgtcacaca gaagtcattt ggacgacagg ccatgaaggc acacaacagt aactcctgac
      961 cttaagccat gtctatgtca aaggaggagc tgagatgggg gctaaacagg aactatatga
     1021 catgaattga ggttgtaatc atgggtgaca tctaaggcat aagatgtcct cagctggacc
     1081 tgcccacttt gtggagagct tttgggacct cttctagata cttggcagga atttgatatg
     1141 atggcaggac aaaaatggta agcctaggca ggaatctgac tgtattactc agggttcgct
     1201 agagtcacag accttatggg tagtctctat atagtaaaag aatttgtact tacactctgc
     1261 agtctaactc ccaacaatgg tcagcagcag ctgtgaatgg gagtccaagg atctagcagt
     1321 tgctcaatcc cacaaggcaa gcaggaaaag agtgagcctt ccttcttcca atgtccttat
     1381 gtagatctcc agcagaaggt gtagcccaga ttaaaggtgt gtgccaccat gcctttaatc
     1441 ccagatgacc ttgaactccc tgtcttaatc ttctggaatc catagccact attcctcaag
     1501 atgtccatac caagatctag gtctgaaact tctatctccc agcctccaga ttaagatcac
     1561 tggtgagcgt tccaattctg gattgtagat catcccagat atagtcaaat tgacaacgag
     1621 gaataggcac tacactgact ttaagctggg actcaggaaa taggcccaga ttaagaacat
     1681 ttatctttga gctaatgcaa actcagagca ggctcagcta aggcaagtgt gaaagtcctt
     1741 ttgtcttagt catcatgact agcccctaga aatggtgttt actggatttt gtttattgcc
     1801 ttgcttattc tctgacccag cactgattta ttgtttgcat gtagataaat tggtataaga
     1861 gcagcctgcg ggaaaaacaa ataaacctgc ttcaacctca
//
