LOCUS       NM_175287               1109 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RIKEN cDNA A430005L14 gene (A430005L14Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_175287 XM_989194
VERSION     NM_175287.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1109)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1109)
  AUTHORS   Ingham,N.J., Rook,V., Di Domenico,F., James,E., Lewis,M.A.,
            Girotto,G., Buniello,A. and Steel,K.P.
  TITLE     Functional analysis of candidate genes from genome-wide association
            studies of hearing
  JOURNAL   Hear Res 387, 107879 (2020)
   PUBMED   31927188
REFERENCE   3  (bases 1 to 1109)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1109)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK039812.1, BC052148.1 and BE994111.1.
            
            On Jul 2, 2009 this sequence version replaced NM_175287.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052148.1, AK039812.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-225               AK039812.1         2-226
            226-1084            BC052148.1         226-1084
            1085-1109           BE994111.1         1-25                c
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 83.78 cM"
     gene            1..1109
                     /gene="A430005L14Rik"
                     /note="RIKEN cDNA A430005L14 gene"
                     /db_xref="GeneID:97159"
                     /db_xref="MGI:MGI:2140680"
     exon            1..86
                     /gene="A430005L14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..764
                     /gene="A430005L14Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UPF0688 protein C1orf174 homolog"
                     /codon_start=1
                     /product="UPF0688 protein C1orf174 homolog isoform 1"
                     /protein_id="NP_780496.2"
                     /db_xref="CCDS:CCDS19003.1"
                     /db_xref="GeneID:97159"
                     /db_xref="MGI:MGI:2140680"
                     /translation="MRSRKLTGGVRSSARLRARSYSSASLASARDVTSSTSAKTTCLA
                     SSSHKATDRRTSKKFKYDKGHLVKAELQKLDPKSDISSLPKVAPVAPCENKFAEDSAE
                     AAVSVPESREPPQGCSTPASEEPSVKAENGLSTEPSSAAAAQEPDDSSAGQAEPVPRT
                     EEVRASVLQMDSSIFLDDDSNQPMPVSRFFGNVELMQDLPPASSSYPSMSRREFRKMH
                     FRAKDDEDDAEG"
     exon            87..200
                     /gene="A430005L14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            201..662
                     /gene="A430005L14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            663..1098
                     /gene="A430005L14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1065..1070
                     /regulatory_class="polyA_signal_sequence"
                     /gene="A430005L14Rik"
                     /note="hexamer: AATAAA"
     regulatory      1070..1075
                     /regulatory_class="polyA_signal_sequence"
                     /gene="A430005L14Rik"
                     /note="hexamer: AATATA"
     polyA_site      1086
                     /gene="A430005L14Rik"
                     /note="major polyA site"
     polyA_site      1098
                     /gene="A430005L14Rik"
                     /note="major polyA site"
ORIGIN      
        1 gacgccgcgc gcgcgctcag agccgcgcga ttgagacttg gcggaggagc gttaggccgg
       61 ggcgctcact catgaggagc aggaagctta caggtggagt gcggtcctca gcacgccttc
      121 gggcccggag ttactcttca gccagcttgg cctctgccag ggacgttacc agctccacat
      181 ctgctaaaac aacatgtctg gcttcctcat cacacaaagc tacggacaga cgaacttcca
      241 aaaagttcaa gtatgacaaa ggtcaccttg tgaaggcaga attacaaaaa cttgacccta
      301 agagtgacat ttcttctttg ccaaaagtgg cccccgtggc tccttgtgaa aataagtttg
      361 cggaggacag tgctgaggct gctgtctctg taccagagag cagagagccg cctcagggct
      421 gctccacgcc tgcgagtgag gaaccctcag taaaggctga gaatggcctg tccacagaac
      481 ccagcagtgc cgctgcagcc caggagcccg atgacagctc tgccggacag gcagagcctg
      541 tgcccaggac agaggaggtg cgggcatccg tgcttcagat ggacagcagc atctttctag
      601 atgatgacag caaccagccc atgcctgtga gtcgcttctt cgggaatgtc gagcttatgc
      661 aggatctgcc accagcctct tcatcttatc cttccatgag cagaagagaa ttcagaaaaa
      721 tgcacttcag agccaaagat gacgaggatg acgctgaggg gtagagctgc gggcgccttg
      781 cagccggtgt caagattctg tatggcatct ttcagagaac acgctctgag aacaaggtgg
      841 acatcagtgt cactggctgg cacagacgcc caggcgcacc atgctggcac agggggctgg
      901 gcagtggaaa acaaggaaaa ctcctgagag ctttggctgt ggtaacaggc ttactttcca
      961 tgccagactg atcaccgggg atgaattctg ctggaaggac tcctgtttct gagtggcgct
     1021 aaccatttga cctggtagtt tttgcaaagt atatatgaga aagaaataaa atatattttg
     1081 aaaatacttt taaagaaaaa aaaaaaaaa
//
