LOCUS       NM_001112735            2001 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus RIKEN cDNA 9930012K11 gene (9930012K11Rik), transcript
            variant 2, mRNA.
ACCESSION   NM_001112735
VERSION     NM_001112735.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2001)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 2001)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB870379.1, AK132259.1 and BC080738.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the central coding region, compared to variant 1.
            The encoded isoform (2) is shorter, compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK132259.1, SRR7345562.3577400.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                BB870379.1         2-24
            24-1982             AK132259.1         1-1959
            1983-2001           BC080738.1         1966-1984
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 36.25 cM"
     gene            1..2001
                     /gene="9930012K11Rik"
                     /note="RIKEN cDNA 9930012K11 gene"
                     /db_xref="GeneID:268759"
                     /db_xref="MGI:MGI:2145726"
     exon            1..171
                     /gene="9930012K11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..1220
                     /gene="9930012K11Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     uncharacterized protein C8orf58 homolog"
                     /codon_start=1
                     /product="uncharacterized protein C8orf58 homolog isoform
                     2"
                     /protein_id="NP_001106206.1"
                     /db_xref="CCDS:CCDS49535.1"
                     /db_xref="GeneID:268759"
                     /db_xref="MGI:MGI:2145726"
                     /translation="MLSRRRVFAVERLGGRDGAFEDLAQGCVVPGVTCTYRRIPDNTH
                     ECSLDFREGQNELRGLERQMPLLKLASQDSGMEMVVGDSSLATLSGLSQDSLNLEPMG
                     SPELPPAQLDRLLARQKLEEVLERSREFPSLSAQRGPLQLLNKPVDGVPIFAGEQEST
                     EADTELEAGLEEAKEVGNMESAACTCLPGQGLRYLEHLCLVLEQMVRLQQLYLQLQTQ
                     RPSRDPEEEVLAPALSSSHIPDNRVQEHREELSQTKDPEGAEAASLPEVGVLVTSPSR
                     LPEALLEPTHILPPSQEPKDLSHWDKVKVLLNRLRWRSPRLPEPPVPPDGSGSRMEFR
                     NLSDRTPCHSQRKTFIPALVVKKPRAKNLSV"
     exon            172..647
                     /gene="9930012K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            648..788
                     /gene="9930012K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            789..891
                     /gene="9930012K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1007
                     /gene="9930012K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1111
                     /gene="9930012K11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1112..1983
                     /gene="9930012K11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1964..1969
                     /regulatory_class="polyA_signal_sequence"
                     /gene="9930012K11Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1982
                     /gene="9930012K11Rik"
                     /note="major polyA site"
ORIGIN      
        1 ctggaaccac gcccatctgg gcagggatcc acgggcagag ccgctccagc acagctaggg
       61 acttggggac gcccgagatc actccggtgc cgctgcagcg gtttccacgt ctggaacacg
      121 ccatgctgag ccggcgccgc gtctttgcgg tggagcgact tggcggccgg gatggggcct
      181 ttgaggacct ggcacaaggc tgtgtggtgc caggagtcac ttgcacctac agacggatac
      241 cagacaacac tcacgaatgt tcactggact tcagggaggg acagaatgag ctgagaggtc
      301 tggagagaca gatgccactt ctgaaactgg cttcccagga ctcgggcatg gagatggttg
      361 ttggggacag ctccttggct accttatcag gactttctca agattctctg aaccttgagc
      421 ccatggggag ccctgagctg cctcctgctc agctagaccg gctgctggcc agacagaagc
      481 tggaggaggt gctggagaga tctcgagagt ttcccagctt gtctgcgcag cgtggccccc
      541 tgcaactgct gaacaagcct gtagatggag tgcccatctt tgcaggagaa caggagtcca
      601 cggaggcaga cactgagcta gaggctggtc tggaagaagc aaaggaggtt ggtaatatgg
      661 agtctgcagc ctgtacctgc cttccaggtc agggcttgcg ctatctggaa cacctgtgcc
      721 ttgtgctgga gcagatggtg aggctccagc agctgtacct gcagctgcag acccagagac
      781 cctctaggga tcctgaggag gaagtattgg ctccagctct ttcatcatca catatcccag
      841 acaatagggt ccaggagcac agagaggagc taagccagac aaaggaccca gaaggtgcag
      901 aggcagcttc acttccagaa gtgggggtgc ttgtcaccag cccctctagg ctgccagagg
      961 ccttgctgga accaacccac atccttccac cctcccagga acccaaggat ctctcccact
     1021 gggataaggt caaagttctg ctcaatcggc tccgttggag gagccctcga cttcctgagc
     1081 ctcctgttcc ccctgatggt tctggatcca ggatggagtt tagaaacctc tctgacagga
     1141 ctccgtgcca ttcccaacgg aagaccttta taccagcatt ggtggttaag aagccacgag
     1201 caaaaaatct ttctgtatga cctcttggtg tacctggtga ccttgggaag aagtccctca
     1261 cattttggct tactgctgct tctctgcact gccaagaaaa gctattggtg cttgctcctc
     1321 ttcaaggtga aggccaaatc catctctaag catcgaagca aggagccctg gatccccaag
     1381 aggttcctga gtgcagttcc agcactcttc cagggctctt cctcctcatc agaaatctct
     1441 gggcttaggc aatgtgaatt gacttattta tcaggtgctc atagagcatg tttagtatgg
     1501 gagtgtgtca gcatgttgca gatgtaagtt tatgcaatct ttgttggact tccgtctgcc
     1561 ccatctgatg gaatcattcg tccaaagggt tggtgtttgg ggtgtcactg gaaggatggc
     1621 accgatcttc attccacaat gaacagttac taatgtggac ttctaatgtc ttcctcatac
     1681 ctgagacggc agccctagga ccaagaacaa cattgccttg ggtacctttg tagtgagtca
     1741 cggctctgga gtacagcccc tgaaggctga atgagggatg gggggaaggt caagaacatt
     1801 gagaggaaca acacataact tgcaaggtca actctaagat gctgtgttct atcctggagt
     1861 ttaaccatag cgaagtctct taatttctga gccacagctt cctacttggg accatgatac
     1921 ccaccttacc tacctcataa gcttgttagg aggatgaagt aacattaaac attctcaatg
     1981 tgtaaaaaaa aaaaaaaaaa a
//
