LOCUS       NM_172286               5565 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RIKEN cDNA 6430548M08 gene (6430548M08Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_172286
VERSION     NM_172286.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5565)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5565)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5565)
  AUTHORS   Zhu,M., Jia,L., Li,F. and Jia,J.
  TITLE     Identification of KIAA0513 and Other Hub Genes Associated With
            Alzheimer Disease Using Weighted Gene Coexpression Network Analysis
  JOURNAL   Front Genet 11, 981 (2020)
   PUBMED   33005179
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5565)
  AUTHORS   Shimogori,T., Lee,D.A., Miranda-Angulo,A., Yang,Y., Wang,H.,
            Jiang,L., Yoshida,A.C., Kataoka,A., Mashiko,H., Avetisyan,M.,
            Qi,L., Qian,J. and Blackshaw,S.
  TITLE     A genomic atlas of mouse hypothalamic development
  JOURNAL   Nat Neurosci 13 (6), 767-775 (2010)
   PUBMED   20436479
REFERENCE   5  (bases 1 to 5565)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK032447.1, AK046401.1, AK133157.1, AK044754.1 and CJ293122.1.
            
            On Aug 4, 2009 this sequence version replaced NM_172286.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1 and 2 encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122299.1, SRR1660817.226371.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-529               AK032447.1         2-530
            530-530             AK046401.1         532-532
            531-1876            AK032447.1         532-1877
            1877-3063           AK133157.1         1845-3031
            3064-3064           AK044754.1         2873-2873
            3065-5562           AK133157.1         3033-5530
            5563-5565           CJ293122.1         404-406
FEATURES             Location/Qualifiers
     source          1..5565
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 68.99 cM"
     gene            1..5565
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /note="RIKEN cDNA 6430548M08 gene"
                     /db_xref="GeneID:234797"
                     /db_xref="MGI:MGI:2443793"
     exon            1..166
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            167..627
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..1522
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="uncharacterized protein KIAA0513 isoform a"
                     /protein_id="NP_758490.3"
                     /db_xref="CCDS:CCDS22716.1"
                     /db_xref="GeneID:234797"
                     /db_xref="MGI:MGI:2443793"
                     /translation="MEAPEVPVGSLIDFETEPPTSPPLEAAPSTLQDPDGSLGDGASE
                     SETTESADSENDMGESPSHPSWDQDRRSSSNESFSSNQSADSAPDEETLALREFMRSY
                     VEKIFSGGEDLDQEEKAKFGEYCSGEDGKGREWFARFVSAQRCKSKCVSEPTFYRLVQ
                     SFAVVLFECHQMDDFGPAKNLMTMCFTYYHLGKPQLPPTEPREKPAGSIDSYLKSANS
                     WLAEKKDIAERLLKNTENMKGFFGGLETKLKGPLVRKNEEDENKPKDRQTKTVTMISP
                     EDEQKGEKVYLYTHLRQQPIWHTLRFWNAAFFDAVHCERRKRSPTTRGDAGEQEEKRE
                     KWCHMTQEERDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCSDFLKKQAVIGNLDEE
                     QYKLLSDHIEQMATE"
     exon            628..727
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            728..801
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            802..872
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1068
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1109
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1188
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1266
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1296
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1377
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1472
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..5565
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5542..5547
                     /regulatory_class="polyA_signal_sequence"
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /note="hexamer: AATAAA"
     polyA_site      5564
                     /gene="6430548M08Rik"
                     /gene_synonym="Kiaa0513; mKIAA0513"
                     /note="major polyA site"
ORIGIN      
        1 agaaggaccc ggcacggctg gtcgcgcggt gcatccgcgg cagctgcaga cccgacggcg
       61 tcctgcccgc ccccctgccc ggtcccgcgg gccgccgcgg cgagagggcc tcgggctgcg
      121 gtgctgcgct cgcgaggggc tgtgcggcgt ggctgcgccg ggaccgacgc cacagggcct
      181 ctgagctgca agagacttcg gccgtggtgg ccaggcgctc cccacacatt gtatacgctt
      241 gcagcttcag gaagctgctc ctcaggctgt gcccatcctg tttggcagcc cagctaccat
      301 ggaggcccca gaagtccctg tgggctccct gattgacttt gagactgaac cacctacctc
      361 ccctcctttg gaagcagcac cgtcaacgct ccaggaccca gatggctccc tgggtgatgg
      421 tgcatctgag agtgagacca ccgagtccgc agacagtgag aacgacatgg gcgagtcacc
      481 ttcacaccca tcctgggacc aggaccgacg ctcttcctcc aatgagtcct tctcctccaa
      541 tcagagtgct gattccgccc cagatgagga gaccctggca cttcgagagt ttatgcgcag
      601 ctacgtagag aagatcttct ctggagggga ggacttggac caggaagaga aagccaagtt
      661 tggggagtac tgcagcggag aagacgggaa aggccgggaa tggttcgcac gctttgtgag
      721 cgcacagcgc tgcaagtcca agtgtgtgtc ggagccaacc ttctaccgcc tggtgcagtc
      781 cttcgcggta gtgctgtttg aatgccacca gatggacgac ttcgggcctg ccaagaacct
      841 catgaccatg tgcttcactt actaccatct gggcaagccc cagctgcccc cgacagagcc
      901 cagggagaag ccagcaggca gtattgactc ctacctgaag tcagccaaca gctggctggc
      961 agagaagaag gacattgccg agcggctgct gaagaacaca gagaacatga aaggcttttt
     1021 cggggggctg gagaccaagc tgaaaggacc gctggtcagg aaaaatgagg aagatgagaa
     1081 caaacctaag gacagacaga cgaagactgt gaccatgatc agccctgagg atgagcagaa
     1141 gggggagaag gtttacctgt acacgcacct gaggcagcag cccatctggc acacgctgag
     1201 gttctggaat gctgcctttt ttgatgctgt ccattgtgag aggcggaagc gatcccccac
     1261 caccagaggg gatgctggag agcaggagga gaagagggag aaatggtgcc acatgaccca
     1321 ggaagaacgg gatgacagcc tgcgcttcaa cgagaacatc accttcgggc agctgggcac
     1381 gttcacccac aacatgctgg cctttggctt gaacaagaag ctatgcagcg acttcctgaa
     1441 gaagcaggct gtgattggca atctagatga agagcaatac aagctgctaa gtgaccacat
     1501 cgagcaaatg gccacagagt aggagatcag cacgtgctcg tctcctagga tctgtcaccc
     1561 cagtgatgac cctgcatgac accagcagca cccagagccg ctccttgctg ccctagaact
     1621 agcagttaaa agactccaga agcctgtctc ccctgcctgt gtctgctctc cctctatgtc
     1681 tatggtgtcc cctgggttac acagctaaac gtgagggacc atctaccccc cacctatcct
     1741 cgagcaccag gcttgtgaga tgagacagag ggtggaggaa gccatgaggg atggtcccca
     1801 cggatcctgc cgagagccac ggacatgtgg ttacagaggc gcaggagggg atccacacag
     1861 ctgcaacgtg aggacagaat cagtgctgtg aatgacagcc tgccactccc tgccacagga
     1921 ctccctgtga gctgtacaga ggaccatgga gccttcctga aaggtctcgg ccatctgttc
     1981 ttctccacct cctcatggga taggaactga aagagaactc aagggttgtc actttcctag
     2041 agggtgtgag cgttctgcca gccacaacca tgtctcagac tcaagagctc cgtcaacaga
     2101 gcctcggaac tggccactca atacagtctc tccctcaata gcacagaagg tccttgagct
     2161 cccaggccgc agcaacacat gcagtgggac gcaggaagcg tgggcgagca ttctcctcgg
     2221 cagctctggg ggggacagag ctaagagcac acagaatgga tctgactgag ggaggagacc
     2281 acgggaaagc aaggttgcct ggtagctcca gcccacagtc ctccccttct gaaagaccca
     2341 cagcgatctg cctcctcagc atccagcgtg ctggctccag agctgctgtt cccatccacg
     2401 ccagtggcct cggtcccttc tgtgccaggc attctggtca ctgaccttga actaggcctg
     2461 caggctctcc tgtcaccccg catcacctca cccttctctg tccctcagcc ttcagtcaca
     2521 tttagtcatg gtctgcctgt gagcgcagtg agttctctcc tgacagctgt gagctcagct
     2581 ggtgtgggtg agcctttcct gcaggaagag cctcccaagg gatggccaaa gaagagcagg
     2641 ataggcaaag ctgtggaatg tacatttcct ggatgtcagg ggtgaccaaa acagtacatc
     2701 agttcctgag atattcaagc aaatgccccc gatagcatag tgtgtgccaa ccggtacacc
     2761 tgactcagca ttaggatcct ataaccatgc ctgtccctgc tctgtgtttt agggaagtga
     2821 cataaagtga ggtcgccctt gctaagtcct gctgtcctct ctagagcctt cctcagagct
     2881 gtgcaagcat gggagcctct ccttgctcct cccagtcctg cactggcatg agttcgggtg
     2941 taggaggaca tgactccaag gtgctgggag atgcaccagt cttgcgcagc agcacctgtg
     3001 gtctggcctc tgccttgccc tcatgcagcc atgagctgcc ttaaggggaa gagtgccaat
     3061 ggtcttcgtg gacttcagaa gtgactttga gactgttcct gctgaccttt tgagatagtc
     3121 acttaaggaa ggatggctct ctctcatctg tctcttgttc cttattgttg cagagctagc
     3181 tccacagagt cagaaagttc tgacccacat tagacccgtg tgcgctgcta aggccatggt
     3241 aaccctctgg ggacaggcag ccattgatgg gagcaaagct tgcaggtgcc tggaggtggt
     3301 cccaccattg cctgcagatg tccttcctct gttcacagtt aggtttagtg agcatttcat
     3361 gtcagggagc ctctggccag tgtctctggg aggtcactaa tctacccctg aggtacccac
     3421 tctttctgtc gtagctttct tctagggccc caacaagcaa gcataaacca ggcttgctgg
     3481 ccagcactcc ttggctcccc tgccgaacca cagacagaca gttcagatta ccaggataat
     3541 cccaagcagt atctccagtc tcggctggta gtggcccaga tctatgcagg cccattagca
     3601 cacattcaaa ccttccgggg ctgtgacctt caaagctgtg taaatcagtg tcaagcacat
     3661 tatagtgttt gccctcacag gaaaaaaaaa aaagtcccct gttctgaaaa caggccagtg
     3721 gtgggccgcc actctgctgc tatcagctct gttaggttat tgtgggtgtt agaggccgag
     3781 cacagcgacc tccagggcac ctctgcggag tgactagcca caggcagagc tgcattgtgg
     3841 tatatatact gagagatctg cattgttcac ctgccagact gggattttcc tctcatctaa
     3901 gacacaaagc gcctaaggtg ctcagcgtct caagaggact ggggtcgagg ctaatctcca
     3961 agctccatct gcaaaggaag gaggtcttcc tagctgagcc gactgtacat ctgcagtccc
     4021 tcactcagga gatgggagca ggaggatcag gagttcaagg tcatccttgg ctacataggg
     4081 ggttcaaagc cagcctgggc ccaatgaaac ctggtctcaa gagaacaaaa ccaaaccaat
     4141 caaatatggt cctaagaatg cagggtggga ttagagccag tgtctctgct tgagatggaa
     4201 tggtgttccc agcctgcctt gtcactcctc acctgagagg aagcagtggg tggtctgact
     4261 ctgcagccca gagacacagg aggcttcagg gacagtgccc tactctagaa acacctgcca
     4321 ctctagatag ttagtgtgag ggatccaggc ttgtgtgagg ggaataatgt ggaaagctga
     4381 ggtctaattg tggtgacgtt agctgtccca ggccacaagc catacccaac cttgaccttc
     4441 ctgggtcaca atgatcagtt ggtttttcca ttagggaggg aaggtctggg cctgcttagc
     4501 aagaaccgct ttattccggt tcccatacca cattcagccg gccaggagac gagcactaga
     4561 ggaaagcagt aggaagggac tctaggaggt ggcactggcc ccacagcctc tgggaagtga
     4621 cagagatgcc tcagctctag gctcctgccc ttgctgctcc caccttccaa gccagttgca
     4681 gagcccctgc taaggaccga gcctgctcac tcatctcagc tccagccgca cagccacagc
     4741 ctcaggtctg tttagcttgg gaagccaaaa gtggatgcct gtgttcatgg gcctcccctg
     4801 ggagttagtg atttggggga ccagcctcac tgcagactcc aggctctgac aggtagtggc
     4861 ctgggcccag ctgcaagcca tgctcccctg agctataacc ccagaaactc tgcactttat
     4921 caagaaagga ccccctcctt atggattgcc ttggctttga ccctgagcta aggctggccc
     4981 tattccatcc ttcttcctag atgatgggtg tgttaatggg aggaaggaaa gagaccctgc
     5041 ctagggaagg ttggcttaca gccacccttg caagaagtgc tggtataggg tcagctgggg
     5101 agaagagccc tggtcagtgg ccttggattg tcacttcttt caggataaag atcccttggg
     5161 ggggggggag ttggatgttt gactactagg agatactaga ggctcagaca gcaggcatgt
     5221 atccccatgg ggaatatgtg aggacctgga ccgctggctg cctcagctgt acctggtttt
     5281 aaatgcagct ttctgtagag attctacctg cagtctgttc tctcttgggg ttccacaccc
     5341 atttcttgcc agcagctccc agtgatgctg tgttttgtat gttagttaca caactttgtg
     5401 tcctgccagg tcatgttcta aaattaaggc tgagaaaggt gtgaggtcga agatctcagg
     5461 cagcgctgtt tcctgtgaag aaaaaaaaag tgtatatatc catagatata gtactttgtc
     5521 ttgtcaggag gtggaaaccg aaataaatta tcttttaaaa agaag
//
