LOCUS       NM_001287087            1775 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus RIKEN cDNA 4933434E20 gene (4933434E20Rik), transcript
            variant 4, mRNA.
ACCESSION   NM_001287087
VERSION     NM_001287087.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1775)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1775)
  AUTHORS   Jeng,E.E., Bhadkamkar,V., Ibe,N.U., Gause,H., Jiang,L., Chan,J.,
            Jian,R., Jimenez-Morales,D., Stevenson,E., Krogan,N.J.,
            Swaney,D.L., Snyder,M.P., Mukherjee,S. and Bassik,M.C.
  TITLE     Systematic Identification of Host Cell Regulators of Legionella
            pneumophila Pathogenesis Using a Genome-wide CRISPR Screen
  JOURNAL   Cell Host Microbe 26 (4), 551-563 (2019)
   PUBMED   31540829
REFERENCE   3  (bases 1 to 1775)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1775)
  AUTHORS   Perez-Garcia,V., Fineberg,E., Wilson,R., Murray,A., Mazzeo,C.I.,
            Tudor,C., Sienerth,A., White,J.K., Tuck,E., Ryder,E.J., Gleeson,D.,
            Siragher,E., Wardle-Jones,H., Staudt,N., Wali,N., Collins,J.,
            Geyer,S., Busch-Nentwich,E.M., Galli,A., Smith,J.C., Robertson,E.,
            Adams,D.J., Weninger,W.J., Mohun,T. and Hemberger,M.
  TITLE     Placentation defects are highly prevalent in embryonic lethal mouse
            mutants
  JOURNAL   Nature 555 (7697), 463-468 (2018)
   PUBMED   29539633
REFERENCE   5  (bases 1 to 1775)
  AUTHORS   Geyer,S.H., Reissig,L., Rose,J., Wilson,R., Prin,F., Szumska,D.,
            Ramirez-Solis,R., Tudor,C., White,J., Mohun,T.J. and Weninger,W.J.
  TITLE     A staging system for correct phenotype interpretation of mouse
            embryos harvested on embryonic day 14 (E14.5)
  JOURNAL   J Anat 230 (5), 710-719 (2017)
   PUBMED   28185240
REFERENCE   6  (bases 1 to 1775)
  AUTHORS   Wilson,R., Geyer,S.H., Reissig,L., Rose,J., Szumska,D., Hardman,E.,
            Prin,F., McGuire,C., Ramirez-Solis,R., White,J., Galli,A.,
            Tudor,C., Tuck,E., Mazzeo,C.I., Smith,J.C., Robertson,E.,
            Adams,D.J., Mohun,T. and Weninger,W.J.
  TITLE     Highly variable penetrance of abnormal phenotypes in embryonic
            lethal knockout mice
  JOURNAL   Wellcome Open Res 1, 1 (2017)
   PUBMED   27996060
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163616.3.
            
            On Nov 4, 2022 this sequence version replaced NM_001287087.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077215.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AC163616.3         159570-159629
            61-245              AC163616.3         160537-160721
            246-465             AC163616.3         160836-161055
            466-567             AC163616.3         161444-161545
            568-685             AC163616.3         164143-164260
            686-739             AC163616.3         164465-164518
            740-906             AC163616.3         166421-166587
            907-965             AC163616.3         166678-166736
            966-1775            AC163616.3         169574-170383
FEATURES             Location/Qualifiers
     source          1..1775
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.2 cM"
     gene            1..1775
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /note="RIKEN cDNA 4933434E20 gene"
                     /db_xref="GeneID:99650"
                     /db_xref="MGI:MGI:1914027"
     exon            1..60
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     exon            61..245
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     exon            246..465
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     CDS             400..1161
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /note="isoform 1 is encoded by transcript variant 4;
                     uncharacterized protein C1orf43 homolog"
                     /codon_start=1
                     /product="protein C1orf43 homolog isoform 1"
                     /protein_id="NP_001274016.1"
                     /db_xref="CCDS:CCDS17520.1"
                     /db_xref="GeneID:99650"
                     /db_xref="MGI:MGI:1914027"
                     /translation="MASSSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRR
                     GPHVPVGHNAPKDLKEEIDIRLSRVQDIKYEPQLLADDDTRLLQLETQGNQSCYNYLY
                     RMKALDAIRASEIPFHAEGRHPCSLMGKNFRSYLLDLRNTSTPFKGVGKALIDTLLDG
                     YETARYGTGVFGQSEYLRYQEALSELATVVKARIGSSQRQHQSAAKDLTQSPEMSPTT
                     IQVTYLPSSQKSKRPKHFLELKSFKDNYNTLESTL"
     exon            466..567
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     exon            568..685
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     exon            686..739
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     exon            740..906
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     exon            907..965
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1775
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1749..1754
                     /regulatory_class="polyA_signal_sequence"
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /note="hexamer: AATAAA"
     polyA_site      1775
                     /gene="4933434E20Rik"
                     /gene_synonym="5730552F22Rik; NICE-3; NS5ATP4"
                     /note="major polyA site"
ORIGIN      
        1 acagtataga caacaggaag tcaaagactg cagcgaaaat atattccacg accagggtcg
       61 cacgtgacgc gaaagggccg cgcacgtcag cgtgcgcgcg cctccccgcc acgaaacact
      121 gctcttgagt tccgcgcgcc cgccccgccc ccgccccgcc ccgcacggat ccgcctccat
      181 cacgtgactc cagtaaggtc tcggcttcct cttactggcg tagttccgcg tctccgcact
      241 cccagcctgg tttttttttt tttttttttt ttaatcgaaa accatatgga aatgttcgga
      301 gagctccagg gaacctaggt tccctggctt cggcagagcc tgggctaacg cgcgagcgcg
      361 gcgggactgt cctagcaggt gttcccggag agagaggcga tggcgtctag tagtaactgg
      421 ctttctggag tgaatgtcgt gctggtgatg gcgtacggga gcctggtatt cgtactgctg
      481 tttatttttg tgaagagaca aatcatgcgc tttgcaatga aatctagaag gggacctcat
      541 gttcctgtag gacacaatgc ccccaaggac ttaaaagagg agatcgatat tcgactatcc
      601 agggttcaag atatcaagta tgaaccccag ctccttgcag atgatgatac cagactactg
      661 cagctggaaa cccaggggaa tcaaagttgc tacaactatc tgtacagaat gaaagctcta
      721 gatgccatcc gtgcctctga gatcccgttt catgctgaag gccggcaccc ctgttcttta
      781 atgggtaaga atttccgctc ctacttgcta gatctgcgaa atactagcac tcctttcaag
      841 ggtgttggca aggccctcat tgatactctc ctggatggat atgagacagc ccgctatggg
      901 acaggggtct ttggccagag tgagtactta cgatatcaag aggccttgag tgagctggcc
      961 actgtggtca aagcacgaat tggaagttct cagagacaac accagtcagc agccaaagac
     1021 ctaactcagt cacctgaaat gtcaccaaca acaatccagg tcacatacct gccttccagt
     1081 cagaagagca aacgccctaa gcacttcctg gaactgaaga gctttaagga caactataac
     1141 acactggaga gcactctgtg atggggctgc acacgtgcag ccgtgcagca ctcgggatgt
     1201 ctggttcagc agacccaggc tttattggcc aaagcattct tacagaacag tgtctaaaag
     1261 gtcattccca accctttctg atattggcta agacctcagt atctcccagt agcacttctt
     1321 ctggatttga attcaaatgt cattcttaac atttctgttg atgcttcttt gaaaatcttc
     1381 gcttgatttt ggctgtaaat cacctaccct gttaaatgct gtttaatccc aaggatgtaa
     1441 gttgaggtga ggtgtcttct ctgtctgccc cattgcactc aactgaatag aaatatttgg
     1501 gtttagagca tctcaaaagt gggtagaatg tcctttggga ttttgttgct ccgtttaaac
     1561 caggtgtatt gtgacatgaa catgactttc ctaaagtgga aggatctgtc cccaccttca
     1621 cccagtcctt aggacaagta gaaaggggca ttctggcact tggcataacc tatgccacga
     1681 tggtgagata atgtgaaaaa gtggtatcct ctgatgtcag cgtattagtc tcagtttaca
     1741 aagtacttaa taaaactaac tactgtaaaa ccatg
//
