LOCUS       NM_001356421            1887 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus RIKEN cDNA 4933430I17 gene (4933430I17Rik), transcript
            variant 3, mRNA.
ACCESSION   NM_001356421 XM_011249972
VERSION     NM_001356421.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1887)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732594.5.
            
            On Dec 15, 2019 this sequence version replaced NM_001356421.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.273603.1,
                                           SRR5189685.200312.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               AL732594.5         118276-118533
            259-411             AL732594.5         124907-125059
            412-556             AL732594.5         125171-125315
            557-614             AL732594.5         129166-129223
            615-715             AL732594.5         131518-131618
            716-779             AL732594.5         133074-133137
            780-943             AL732594.5         134458-134621
            944-1091            AL732594.5         135291-135438
            1092-1149           AL732594.5         135783-135840
            1150-1196           AL732594.5         136110-136156
            1197-1239           AL732594.5         136352-136394
            1240-1361           AL732594.5         138675-138796
            1362-1425           AL732594.5         139920-139983
            1426-1887           AL732594.5         140188-140649
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 33.17 cM"
     gene            1..1887
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /note="RIKEN cDNA 4933430I17 gene"
                     /db_xref="GeneID:214106"
                     /db_xref="MGI:MGI:3045314"
     exon            1..258
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            259..411
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..1655
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /note="isoform 2 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="uncharacterized protein C9orf43 homolog isoform
                     2"
                     /protein_id="NP_001343350.2"
                     /db_xref="GeneID:214106"
                     /db_xref="MGI:MGI:3045314"
                     /translation="MNVADESQWDEAVCTLSGCQHPQCWASLRRIERGHPRILDPSPK
                     SPRETEDKLPTLTIVNITDTCLWTQKRVAQQQPSEFTFPKDRPSLSKPASKRQSRSPK
                     ALRDKDVTSRSPRPLKLSVLNLNEAKLPLSENVSNMVVTWVPEETEKDVSPVQKTDVS
                     SWPGKKRRKKLRKKSKPSLYYPGRQYSRSPAAIVPPPSPEHHLEQLSPEAIPLWAQVG
                     MLPQDLLEECILAHEKSIIGPEVKIELSKMRKSLPLERRRPESAISSKMYLTIQRLTL
                     QRPSLRYPARLRKLCPNLKQDSLMQQGKAKTFPPKQEPKKKAKRNVKGQYGEETTSGH
                     FFHDSVGLRISGQEDQQTPWEEEDIEKTSAETHVSLEEVYEFDKYYTEYYATPESAVL
                     YETVYQNLDDDEETMVGIKASSKDRNLKNLSAMMDGIGWNPELKLLRILQATEEEDEE
                     GHNSRAQSKTSLEA"
     exon            412..556
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            557..614
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            615..715
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            716..779
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            780..943
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1091
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1149
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1196
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1239
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1361
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1425
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1887
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1868..1873
                     /regulatory_class="polyA_signal_sequence"
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /note="hexamer: ATTAAA"
     polyA_site      1887
                     /gene="4933430I17Rik"
                     /gene_synonym="bN189G18.7"
                     /note="major polyA site"
ORIGIN      
        1 gctcggaact cagtgtagat tttcattcaa ttctattgca ccgattgatg cagtagtatt
       61 gtccatcttt aatcttatgc ccttcacaac tttgtgataa ttatattaag gataagtgtt
      121 aatctaaaat ttcgtttaaa aaaatgccat tactttacta ggacagcagt aacaagggca
      181 atatcaaaag acgcctgatg agacttcgga gctcaatttg gtctggttcg gtactgaaag
      241 cgcaagaatc atttgattct atgaacgtgg cagatgagtc ccagtgggac gaagccgttt
      301 gtaccttgtc aggttgtcag catccacagt gctgggcatc tctccgacgg attgagaggg
      361 gccatcctag gatcctggac ccatccccca aatctcccag agaaactgaa gataaactcc
      421 cgacactcac cattgtaaac atcacggata cctgcttgtg gacccagaag agggtggctc
      481 agcaacaacc atcagaattt accttcccca aagatcgtcc ctcattgtcg aagccagcct
      541 ccaaacgtca gagcaggtct ccgaaggctt tacgtgacaa agatgtgact agccgttctc
      601 ctaggcctct caaactctca gtgttgaatt tgaatgaagc aaaacttcct ctctctgaaa
      661 atgtcagtaa catggttgtg acctgggttc cagaagaaac ggagaaggac gtgagcccag
      721 ttcaaaagac tgatgtttcc agctggcctg ggaagaaaag gagaaagaaa ctgcgaaaga
      781 aaagcaagcc atctctgtac taccctggaa ggcagtactc gagaagtcca gcggcaattg
      841 tacctccccc ctccccagaa caccacttgg agcaattaag tcctgaagcc ataccactat
      901 gggctcaagt tggcatgctt ccccaggacc tgctggagga gtgcatcttg gcacatgaga
      961 aatccataat tggccctgag gtgaagatag agttgtccaa gatgagaaag agtcttcctc
     1021 tggaaaggag gcgacctgaa agtgctatct catctaagat gtatctgact atccaacgcc
     1081 tcaccctgca aagaccatca ctgcggtatc ctgctcgtct gaggaagctt tgccccaacc
     1141 tgaagcaaga ttccttgatg cagcagggga aggcgaaaac ctttcctccg aaacaggagc
     1201 ctaagaagaa agccaagaga aatgtcaagg gccagtatgg ggaagaaacc acgtcgggcc
     1261 atttcttcca tgacagtgta ggactcagaa tatcaggaca ggaagatcaa caaacgccgt
     1321 gggaagaaga ggacatagag aaaacatctg cagagacaca tgtttcctta gaagaagtgt
     1381 atgagtttga caagtactac acagaatact acgccactcc ggagagcgct gtactatatg
     1441 agacagttta ccagaacctt gatgatgacg aggagactat ggtgggaatc aaggcttcca
     1501 gcaaagaccg taacctcaag aacctttctg caatgatgga cggcatcggc tggaaccctg
     1561 agctcaaatt gctgaggatt cttcaggcca ctgaggagga agatgaggaa ggccataatt
     1621 ctagggcaca gagtaagacg tctctagaag cttagctcaa atcatcactt tgggcagctt
     1681 tagccagaga gttcttggta ttctgaggac aacaaccttg gacacaggga agaaaagaga
     1741 gaatgttgtt ctctggatcc tccagcagga ccaggcccta gataccctgt attcttcatt
     1801 tactctttac ctccaaaacg agtaagaaaa agccctaatc ctatggaata taggcagctt
     1861 ttccatcatt aaacacaact ccttcta
//
