LOCUS       NM_001361564            4605 bp    mRNA    linear   ROD 08-OCT-2024
DEFINITION  Mus musculus RIKEN cDNA 4933427D14 gene (4933427D14Rik), transcript
            variant 2, mRNA.
ACCESSION   NM_001361564 XM_006534368
VERSION     NM_001361564.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4605)
  AUTHORS   Li,M., Wang,Y., Wu,X., Chen,Q., Huang,J., Zhu,H., Yang,S., Wang,J.,
            Li,L.T., Liu,X., Fu,K., Song,F. and Wang,C.
  TITLE     KIAA0753 enhances osteoblast differentiation suppressed by diabetes
  JOURNAL   J Cell Mol Med 28 (17), e70035 (2024)
   PUBMED   39245790
  REMARK    GeneRIF: KIAA0753 enhances osteoblast differentiation suppressed by
            diabetes.
REFERENCE   2  (bases 1 to 4605)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 4605)
  AUTHORS   Kumar,D., Rains,A., Herranz-Perez,V., Lu,Q., Shi,X., Swaney,D.L.,
            Stevenson,E., Krogan,N.J., Huang,B., Westlake,C.,
            Garcia-Verdugo,J.M., Yoder,B.K. and Reiter,J.F.
  TITLE     A ciliopathy complex builds distal appendages to initiate
            ciliogenesis
  JOURNAL   J Cell Biol 220 (9) (2021)
   PUBMED   34241634
REFERENCE   4  (bases 1 to 4605)
  AUTHORS   Costello,I., Nowotschin,S., Sun,X., Mould,A.W., Hadjantonakis,A.K.,
            Bikoff,E.K. and Robertson,E.J.
  TITLE     Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern
            anterior mesendoderm, node, and midline development
  JOURNAL   Genes Dev 29 (20), 2108-2122 (2015)
   PUBMED   26494787
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX119911.6.
            
            On Mar 29, 2018 this sequence version replaced XM_006534368.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK173018.1, SRR13948564.4339159.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-287               BX119911.6         170180-170466       c
            288-426             BX119911.6         165396-165534       c
            427-1027            BX119911.6         161347-161947       c
            1028-1134           BX119911.6         158767-158873       c
            1135-1197           BX119911.6         157544-157606       c
            1198-1413           BX119911.6         154403-154618       c
            1414-1624           BX119911.6         152532-152742       c
            1625-1848           BX119911.6         143387-143610       c
            1849-2015           BX119911.6         141389-141555       c
            2016-2135           BX119911.6         139645-139764       c
            2136-2225           BX119911.6         138471-138560       c
            2226-2315           BX119911.6         138187-138276       c
            2316-2394           BX119911.6         132765-132843       c
            2395-2481           BX119911.6         131700-131786       c
            2482-2667           BX119911.6         129622-129807       c
            2668-2749           BX119911.6         128501-128582       c
            2750-2870           BX119911.6         122384-122504       c
            2871-3095           BX119911.6         121776-122000       c
            3096-4605           BX119911.6         116913-118422       c
FEATURES             Location/Qualifiers
     source          1..4605
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11"
     gene            1..4605
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /note="RIKEN cDNA 4933427D14 gene"
                     /db_xref="GeneID:74477"
                     /db_xref="MGI:MGI:1921727"
     exon            1..287
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            288..426
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     CDS             334..3213
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /codon_start=1
                     /product="protein moonraker"
                     /protein_id="NP_001348493.1"
                     /db_xref="CCDS:CCDS24979.1"
                     /db_xref="GeneID:74477"
                     /db_xref="MGI:MGI:1921727"
                     /translation="MGPSQPASTCVHLAPSLQLDAMSDPRNLQPQNQLQFNRNVPTNP
                     SNLAVRYSCPHGIKIEKLKHSYNELNHGKDLDFKAGNELSSSVSFSVISEERLSYAVH
                     LAKRDVKRRQFEEHVKDHLRSLPHSSHKGMHTKVERKDSKSQDVCHCSHQPSRVSLSS
                     SGAKVYVYTSQPGRADLTVPNSPPTHDPGLQPQPRIEENKNLWEQKGLLEVQRLQKEL
                     SGCIRKIEALTKKDRLEEALDPDEEHRIRVRRQEQAVRCARMLYVLQQQVKEIQEELD
                     KLSPQKIKHTKKSWAVSRLAAAHRAAIRALQVFVTQFTDRGEHPVPARCRELGSLIRQ
                     LSLCSAKLDADPSVPDVVIDILQQIEALESLLEKKLSPKKAKKCFTEIRSRFPVGSQK
                     ILERWPTVLPKSERRPLVTKETFPQETSRPPVAKRLLAAMCQPDGELQRLESEPDVLD
                     AHLLPEEAPRIEDNGTDFKDGTLTPAKPQAVRRKALTGSMPIRKKDTVESARPQQGLH
                     IAERNRPNQPYSKSRLQQTTVSSRLKMNRQPMKDHRAPWIPPNPTSPPASPKCAAWMK
                     VKYSPRDAAKEQSLQQEDTHKESQLRGDAEQEAARLSWPDAESSKRLKELEELEAKEM
                     ERKQKQRLNWLEAETSRRTKELDELKAEEMDRLQKLSVSATQLADKVEEAVLERLKPL
                     LIKAQRVNSSVEANSHLKDRPSRHAAAAAQPAEQASDVRFESRNIPQLRDCLEDTAHE
                     LWARTQDKILGSETSARLGDSKDSPDLETMMLRMEEMEKYQETVRQRYNKIVYADPHL
                     WMHEERNDQNTPAVSEGPLASHPIKITKTATQKCPAVNILLERPCNANSLDESVTTEE
                     GSEKREAPLPLSREDLHQRKGQTPLSVPPRMRHSIGAYCSRFEQFLRIIAHEAIGSFN
                     PWLIAESFSDELVDEALGAVAAELQDVCEDYAEAVFTSEFLEAAA"
     exon            427..1027
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1134
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1197
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1413
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1624
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1848
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..2015
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2016..2135
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2136..2225
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2226..2315
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2316..2394
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2395..2481
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2482..2667
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2668..2749
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..2870
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..3095
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     exon            3096..4605
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4411..4416
                     /regulatory_class="polyA_signal_sequence"
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /note="hexamer: AATAAA"
     polyA_site      4437
                     /gene="4933427D14Rik"
                     /gene_synonym="Gm43951; Kiaa0753; MNR"
                     /note="major polyA site"
ORIGIN      
        1 ataactcctt agggccgtcc ttttggtctg ctggagtttc tttttggcgc cagtttccct
       61 cagacaacta gacgcctgac ctggtctggt ccccaccctg gcttcatgga cagtgacggc
      121 aaagcccgtc gcggtacaac accttgatcc tcaaatggct caggaagatc aacggctccc
      181 aaacagccgc gcgcctgttg ccatgacgac tgggcgagag gccggaagcg aggcctagcg
      241 tggggtcgcc ttacgatctc ttggtggccg cgccgcgccc aaaccagatt tgcctgataa
      301 ctaggcagcc gctcatgttc atcatctgac ctgatgggac caagccagcc agcttctaca
      361 tgtgttcatc tagcacccag tctccaactg gatgccatga gtgaccccag gaaccttcag
      421 ccccagaacc agctgcaatt taataggaat gttcctacaa atcccagcaa cttggcagtc
      481 cggtactctt gcccacatgg aattaaaatt gaaaaactga aacactcata caatgaattg
      541 aatcatggta aagacttgga ttttaaagct ggaaatgaat taagcagttc tgtctcattt
      601 tctgtcatat cagaagagag gcttagctat gctgtccacc tagccaagag agatgtaaaa
      661 cgaagacaat ttgaagaaca cgtgaaagat catctcagaa gtctgcccca tagctctcac
      721 aaaggtatgc acaccaaggt ggaaaggaag gactccaaga gtcaggatgt ctgtcattgc
      781 agccaccagc cgtccagagt aagcctctcc agctcgggcg ctaaggtgta tgtgtacaca
      841 tctcagccag gacgagctga tcttactgtg ccaaattcac cacctaccca tgatccagga
      901 cttcagccgc aacccagaat agaggagaac aaaaacctgt gggaacagaa aggcctgcta
      961 gaagttcagc gactccaaaa ggaattgagt ggttgtatcc gtaagataga agcactaacg
     1021 aaaaaagata gactagaaga ggctttggat ccagatgaag agcatcgaat ccgagtcagg
     1081 agacaggagc aagccgtgcg ctgtgcccgc atgctctacg ttcttcagca gcaggtaaaa
     1141 gaaatccagg aagaattgga taaattgagt ccacaaaaaa ttaaacatac taagaagtca
     1201 tgggcagtgt ctaggctggc agccgctcat cgagcagcca tccgggcctt gcaagtgttt
     1261 gtcactcagt ttactgaccg aggggagcac ccagttcctg ctcggtgtag ggagctgggc
     1321 agccttattc gtcagctgtc gctgtgttcc gccaagctgg atgctgatcc ttctgtgcca
     1381 gacgtggtca tagacatctt gcagcaaatc gaggctttgg agtctctcct ggaaaagaaa
     1441 ttgtcaccta aaaaggcaaa gaaatgtttc acagaaattc ggagcagatt tcctgttggt
     1501 agccaaaaga tcttagagag atggccaact gtactgccca aaagtgagag gagacccttg
     1561 gtcacaaagg agacattccc acaggaaacc agtcgacctc ctgtggcaaa gaggcttctt
     1621 gcagctatgt gtcagcctga tggggagctt cagaggctgg agagtgaacc cgatgtgctg
     1681 gatgcacatc ttcttccaga agaagcccct cgtatagagg acaatggtac agacttcaaa
     1741 gacggaacat taaccccagc caaaccacag gcagtgagaa ggaaggcttt gacagggtcc
     1801 atgccgatta ggaagaaaga tactgtggag tcagccagac cacagcaggg actccacata
     1861 gctgaaagaa atcgaccaaa ccaaccttac agcaaaagca ggttgcagca gacaacagtg
     1921 tcatccagat taaaaatgaa ccgacagcct atgaaagacc atagggctcc ttggatacct
     1981 ccaaacccca catccccacc agcctctcct aaatgtgctg cgtggatgaa ggtgaagtac
     2041 agccccaggg atgctgcaaa ggagcagtcc ctacagcaag aggataccca caaggaaagt
     2101 cagctgagag gtgatgctga gcaagaagca gccaggcttt cttggccaga tgctgagtct
     2161 tccaaaagac tgaaggaact agaagaattg gaagccaaag aaatggaaag aaagcaaaag
     2221 cagaggctca attggcttga ggctgagact tctagaagaa ccaaagagtt ggatgaactg
     2281 aaagctgaag agatggatag acttcaaaaa ttaagtgtct ctgccaccca gttagctgac
     2341 aaggtggagg aggcagttct ggagcggttg aagcccctct tgatcaaggc ccagagagtg
     2401 aattcttcgg tggaagcaaa tagtcatttg aaggatcgtc cgtcacggca cgcagcagca
     2461 gcagcccagc ctgccgagca ggcttcagat gtacgttttg aatccaggaa tattcctcag
     2521 ctgcgtgact gtttggaaga tactgctcat gagctctggg ctaggactca ggataagatc
     2581 ttggggtcag aaacttcagc cagattgggg gacagcaagg acagcccaga tctagagacc
     2641 atgatgctcc ggatggaaga aatggaaaaa taccaggaga cagttcgcca aagatataat
     2701 aaaattgtat acgctgaccc tcacttatgg atgcacgaag aaagaaatga ccagaacacc
     2761 ccagctgtaa gtgaaggacc tttggcttcc cacccaatca agatcaccaa gacagcaact
     2821 caaaagtgcc ctgctgtgaa catcttgtta gaaaggccct gcaatgccaa ctcactggat
     2881 gaaagtgtaa caacagagga gggatcggag aaaagggagg ctcccctgcc cctctccaga
     2941 gaagacctgc atcagagaaa agggcaaact cccctctcag tcccacccag gatgcggcac
     3001 agcattggtg cttactgtag ccggtttgag caattcctac ggatcatagc tcatgaggct
     3061 ataggctcct tcaacccatg gctaatagct gaaagctttt cagatgagct ggtagatgaa
     3121 gcactggggg ccgtggctgc agaactgcag gatgtgtgtg aagactatgc agaagctgtg
     3181 ttcacctcag agttcctaga ggccgctgca tgagagctgt ccaggcaggg ccctcagatc
     3241 actgccggag agtcagcgcc acccgctgtc agcccgtggg ggaatctctg tcctcagctg
     3301 cccactgaag gatgccaggg agctcaccct ctccttgtct tagcagtgct tctagaagtt
     3361 ataaaaaggt gggttacatt tgctagcgcc tgaggagcat gagacaatta gaaaggtaca
     3421 acatttcaga atgtataatt ttcctctgac tcagttggaa atcaaaatgt tttgaaaggt
     3481 aatggataaa gatatttcac atagggattc cagcctctgt taaacccatg ggggtggagg
     3541 gatcagtgct aatccaagtg ccgttactgt ctggtcccag cacctggctc ctgttggcaa
     3601 gtgtgctcat cacattgtca ctggtggtgt cgccttcctg ggcggcaagc tacatggaat
     3661 gcagagtggt ggtgccacta agcctctgct cagtggcagt ggaagtgggg agcccagcgc
     3721 acgggcacac ggaacacaca ggcccaagca caccttgctc cgtggctctc actttctagg
     3781 gtgtttcacg ttctcagttt ctcagagtca cttattgctg tttggacaca tgctagtata
     3841 aaaagcattt ctctgaatat agaagaattt gaagacaggc cttccccatg ccagctcact
     3901 cccagagagc agaagcgtct gcaccatgga gcatcccatc tggaggaggg aatcaagccg
     3961 gtgacttgag gactttgggc tcttctgagg accaacgatg ctgcgtggcc tttgaaggct
     4021 cttaggtccc ggtggcaagg tcctcaggac tcgggattga gaaacagaaa aggaatgtgc
     4081 gtacaaatag gcagtcaccc gaaaagactt ttcctggatc cgtttgcctc agctatttgt
     4141 gggaggcttg gtgaaggaag ggtaaggaac aaagggagag acacccaagg acgaatgtga
     4201 gtctgttacc acagacgcct cgacatggtc tcctggggtg gtttctaagg taccttcctg
     4261 tttaatacta cataacctcg gaaaggacat caagggactc ataggtcttc agtctggaga
     4321 gttaaacatg tacacttgaa ccggtagaat cccttgtcat tggtagtcct catttgtcat
     4381 ttgcggtttt tactgtgctg attaaaaaaa aataaactca gtattttaaa ttgtgaacat
     4441 gtctatttga agtaatttac atctcctttt tcccacaggt aatgtgaaat ggaatttaca
     4501 ggaaccactg ggaagggaat acttttgtat ttgatatgaa catagtagac tatttgccac
     4561 ctcagagaaa aaggaatgct aataaaacct aacatttatt gagca
//
