LOCUS       NM_172967               2291 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus RIKEN cDNA 4930503L19 gene (4930503L19Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_172967 XM_001001474 XM_001001484 XM_001001495 XM_001001505
            XM_001001515
VERSION     NM_172967.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2291)
  AUTHORS   Rutledge,E.A., Benazet,J.D. and McMahon,A.P.
  TITLE     Cellular heterogeneity in the ureteric progenitor niche and
            distinct profiles of branching morphogenesis in organ development
  JOURNAL   Development 144 (17), 3177-3188 (2017)
   PUBMED   28705898
REFERENCE   2  (bases 1 to 2291)
  AUTHORS   Liu,P.Y., Vikis,H., James,M., Lu,Y., Wang,D.L., Liu,H.B., Wen,W.D.,
            Wang,Y. and You,M.
  TITLE     Identification of Las2, a major modifier gene affecting the Pas1
            mouse lung tumor susceptibility locus
  JOURNAL   Cancer Res 69 (15), 6290-6298 (2009)
   PUBMED   19622765
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK037066.1.
            
            On Apr 6, 2007 this sequence version replaced NM_172967.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK037066.1, SRR7652917.679488.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2291              AK037066.1         2-2292
FEATURES             Location/Qualifiers
     source          1..2291
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 44.42 cM"
     gene            1..2291
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /note="RIKEN cDNA 4930503L19 gene"
                     /db_xref="GeneID:269033"
                     /db_xref="MGI:MGI:1922045"
     exon            1..190
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     exon            191..497
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     exon            498..826
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     CDS             535..2115
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; lung adenoma susceptibility protein 2"
                     /codon_start=1
                     /product="lung adenoma susceptibility protein 2 isoform 1
                     precursor"
                     /protein_id="NP_766555.1"
                     /db_xref="CCDS:CCDS29333.1"
                     /db_xref="GeneID:269033"
                     /db_xref="MGI:MGI:1922045"
                     /translation="MAKLNTKLRGCSQESSVSSLLASGSLSGSRSDSAHSAHSSFVYK
                     DQLYSSASEALQAYIDDFDLSREHPGANAVKVNTDGEIGNGLQFSSYVHIPDNAFVNL
                     DPKQHFNPLYYRRETVNDMDAISLTTDDLLRLPADGCFSFPCVPPDHRPNKKYSGRQD
                     SSDIKNSPSFYVDATSKSKNNIVPPYVYTNINGKKCGRPRTPKPINRENKCVSESSLS
                     FPKESSFTEDSAERRLENYPRWLTSQKSDLSVSGVTSIPDVKYPIWLHNQDLLPEANT
                     PRGYKLLNEDEYRPIHSYQTQRANQLLNKIDCFEYTFKPSNLTDSFSEYEGLGNEFKC
                     QCDNPLLPGQSQKPFCGDKIELLILKAKKNLKQSAKDLPKPVEKDDSPCSLDKLEAER
                     TWENVPVAFKSPVPVKADDSPQQSSRTQCVNAFLEDFLNGENQSSTLSGGKHHGPVEA
                     LKQMLFNLQTVQESFNKNKTTEPEEEIKQVSEDDLAKLQMKENMMPITRSLHKALQHL
                     SRLRDLVDDTSGRQSPKK"
     exon            827..1585
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     exon            1586..1736
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     exon            1737..1839
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     exon            1840..1971
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2042
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     exon            2043..2291
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2139..2144
                     /regulatory_class="polyA_signal_sequence"
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /note="hexamer: AATAAA"
     polyA_site      2161
                     /gene="4930503L19Rik"
                     /gene_synonym="9930107F24; Lars; Las2"
                     /note="major polyA site"
ORIGIN      
        1 atgttgggtc ggtttgaaag cgagcgcggg cgtccggcct tcctgcggtg gcggaggaaa
       61 tagcggtccc gaggaaggcg gtgacgcgct ccgggatgct ttgtcgcgtc gtccggtttg
      121 ggcagggctt gggctgtccg ccgcccggag tctggaagtg cgcgctttaa aaaaaaaaaa
      181 aagtgtcccg ggacgctgcc accctggagc cagcccgaca gccacaccca gcgcacaggg
      241 atggtcccag tctctgcagc ccaaggcctg ccataaccgg tgttccagac ccgttgcctt
      301 ggcaggctaa ccagagagca gcggtttcca agagttgtgc tccgcttcca gagcgtccat
      361 ctccctggca cttttttgac gcggtcgggt cgtctgtgtt ttgaatcgag gtagttgaca
      421 tttcttgccc taacttttat tctgcaccgc gatggattta attcgggaga ttgaaaccgg
      481 cgcttttgaa gggaatgtat ttaatggaaa tgaataactc cttttgagaa agccatggcg
      541 aagttaaaca caaagctcag gggttgttct caagagtctt cagtatcttc tctcctggca
      601 agcggcagcc tgagtggcag ccgctccgac agcgcccaca gcgcccacag ctcgtttgtg
      661 tataaggacc agctgtacag ctcggcttcc gaggccctgc aggcctatat tgatgatttt
      721 gacctgagca gagaacatcc tggtgcaaac gctgtcaaag tgaacactga cggtgagatt
      781 ggtaatgggc tgcaattttc cagctacgta catatacccg acaatgcttt tgtcaatctt
      841 gatcccaagc agcactttaa ccccttatac tatagaagag agactgttaa tgacatggac
      901 gccattagcc tgacaactga tgatttgtta agacttccag cggatggatg cttttccttc
      961 ccttgtgttc cacctgatca ccgaccaaac aagaaataca gtggaagaca ggattcatca
     1021 gacattaaga atagtccaag tttttatgta gacgctactt ccaagagcaa gaataatata
     1081 gttcctcctt atgtatatac aaatataaat ggaaagaaat gtggtaggcc cagaacccca
     1141 aaacctatta acagagaaaa taaatgtgtt tcggaatcat ctttatcttt tcctaaagaa
     1201 tcatccttca cggaggacag tgcagagcgc aggctcgaga actatccaag atggctgact
     1261 agccagaagt ctgacctcag tgtctcaggg gtaactagta tacctgacgt taagtatcca
     1321 atttggctcc ataatcaaga cttgctacct gaggcaaata ctccaagggg ttataaatta
     1381 cttaacgaag atgaatatcg ccctatacat agttaccaaa cacaaagagc aaatcagctg
     1441 ttaaataaaa tagattgttt tgaatatact tttaaacctt caaacttaac agactccttc
     1501 agtgagtatg aaggattagg taatgaattt aaatgtcagt gtgacaatcc acttctccca
     1561 ggacaatccc aaaagccatt ctgtggtgac aaaattgagt tgcttatcct gaaggctaag
     1621 aagaatctca aacaatctgc taaagactta ccaaaacccg tggaaaagga tgacagtcct
     1681 tgctccttag ataaacttga agcagaacga acgtgggaaa atgtccctgt ggctttcaaa
     1741 tctcctgtcc ctgttaaagc tgatgacagt cctcaacaaa gttccaggac acaatgtgtg
     1801 aatgcgtttc ttgaggactt tttaaacggt gagaatcaga gctctactct atctggaggc
     1861 aaacatcatg gtcctgttga agctttgaaa caaatgttat ttaaccttca gacagtacag
     1921 gaaagtttta ataagaataa aactacagag cctgaagaag agattaagca agtgtcagag
     1981 gatgatttgg ctaaattaca gatgaaggaa aatatgatgc ctattactag gtctcttcac
     2041 aaggccttac aacatttatc ccgcctgaga gacctggtcg atgataccag tgggagacag
     2101 tcaccaaaga agtgaagagg aaaataagcc ttcaccgcaa taaacagtca ccacacaatg
     2161 agttatgtac tctctgctgt tacttacacc gagaaggtga acattagcca tacgttattc
     2221 tgtggccagt tcaagtggat ttacttctaa gaatctgaac ttggaaatat tcataggccc
     2281 gattttatat g
//
