LOCUS       NM_001195097            5553 bp    mRNA    linear   ROD 22-DEC-2022
DEFINITION  Mus musculus RIKEN cDNA 3425401B19 gene (3425401B19Rik), mRNA.
ACCESSION   NM_001195097 XM_003085016 XM_484361 XM_985544
VERSION     NM_001195097.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5553)
  AUTHORS   Dierck F, Kuhn C, Rohr C, Hille S, Braune J, Sossalla S, Molt S,
            van der Ven PFM, Furst DO and Frey N.
  TITLE     The novel cardiac z-disc protein CEFIP regulates cardiomyocyte
            hypertrophy by modulating calcineurin signaling
  JOURNAL   J Biol Chem 292 (37), 15180-15191 (2017)
   PUBMED   28717008
  REMARK    GeneRIF: Data suggest that Cefip (cardiac-enriched Fhl2-interacting
            protein) interacts with Fhl2 (four and a half LIM domains
            protein-2) and modulates calcineurin signaling in cardiomyocytes;
            Cefip is located at sarcomeric z-disc and is up-regulated in
            several models of cardiomegaly.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT009541.12, AK132190.1 and AA467296.1.
            
            [WARNING] On Apr 13, 2023 this sequence was replaced by
            NM_001195097.2.
            
            On or before Jan 14, 2011 this sequence version replaced
            XM_003085016.1, XM_985544.1, XM_484361.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK132190.1, SRR10223971.14169.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                CT009541.12        76996-77013
            19-741              AK132190.1         4-726
            742-5452            CT009541.12        98344-103054
            5453-5553           AA467296.1         190-290
FEATURES             Location/Qualifiers
     source          1..5553
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14"
     gene            1..5553
                     /gene="3425401B19Rik"
                     /gene_synonym="Cefip"
                     /note="RIKEN cDNA 3425401B19 gene"
                     /db_xref="GeneID:100504518"
                     /db_xref="MGI:MGI:3588196"
     exon            1..270
                     /gene="3425401B19Rik"
                     /gene_synonym="Cefip"
                     /inference="alignment:Splign:2.1.0"
     exon            271..364
                     /gene="3425401B19Rik"
                     /gene_synonym="Cefip"
                     /inference="alignment:Splign:2.1.0"
     exon            365..487
                     /gene="3425401B19Rik"
                     /gene_synonym="Cefip"
                     /inference="alignment:Splign:2.1.0"
     exon            488..5547
                     /gene="3425401B19Rik"
                     /gene_synonym="Cefip"
                     /inference="alignment:Splign:2.1.0"
     CDS             660..4898
                     /gene="3425401B19Rik"
                     /gene_synonym="Cefip"
                     /note="cardiac enriched FHL2-interacting protein;
                     uncharacterized protein C10orf71 homolog"
                     /codon_start=1
                     /product="cardiac-enriched FHL2-interacting protein"
                     /protein_id="NP_001182026.1"
                     /db_xref="CCDS:CCDS49437.1"
                     /db_xref="GeneID:100504518"
                     /db_xref="MGI:MGI:3588196"
                     /translation="MMQGNKKCTDGFSDTSSIGSVLDEADREVSNLTDRAFRSLCISE
                     DTSFHDSDLALSPDVTSQVSGTFHQETVGHANRKSGIWSQLPSQGTEHSGWAATFQQQ
                     PKYVQGEEKYPKTSPLPTPVQRRLEVPISGLRSSSKPISKVSSLIRSFDRTETQSCDS
                     RPPPSKPPALKNPPKFAHPPESGVNFCFDSAFLTVRRVPAEVSNTHQGSHQSGRAPGE
                     QESPKNPEIASHSSDSLLRTPDHVAGSFEPRYPSPPLKPATAEPGRGKEWIPRRTFLH
                     SENSAFESWDTHQPKLRERKDIAETTPESKAPKHYEDMPLLKEPYPAESKGSPYQARA
                     NCAQEENRSPSGSQSTSGAWGARDPGSQLFPVEGNASQIDPQVKRSKAPWRKPKTGKG
                     GTDGPPDALEDKKQPNRRGLPLYSKLNPQGQLPENGVLDMPEESNDHYNPPFNISKLL
                     TPIISTKHVLETSDTQPVEISPSPPGQLNGYQEKESSEAQSRDSYKSKAPSLLFNLKD
                     VRKRVKSTYSPLPLLKGFDEKTRGKLDSKQEPLSNGVTLPDGLEENPPTELLPDNVPG
                     VLHSSTQKDPAINSRESFAVSHPTFSSPSASSQTHFCVNGEAAESNSNEKEEANGESE
                     LDPSKGGGHPDCRENLPRKHLSLKLFNRESEMGPAMAEMKPHQLENGLSRSVSQETET
                     ERETGFQSLPLNQKFSPGPLSPEEEDVFYSDSQSDFTPCRQTKAKFSTSSSDQSFASF
                     EDQQKVCFTEGPQEDRKSHVSAGDKQRDETAVEKEESQQCASRNEHRGVDEQRQEEIQ
                     RKAQGVSGGRPRKASAEDLSARGSWMGADKDTAHTHAKDPTPLPASTNKHRLFPIKDN
                     TLRATPVIKPIILPLLRTVSSEDSLSSGHQENELPKQLWGEDAGGLSASESQEMPNTP
                     LSNNDVPGTQHRCMVCEDVQEDPVHTAAQDETSQQTRKGSFSFLPPVEEENRMKPSPD
                     TAGEGLAQEKSKSADLGKLGVPQRIPTIALLPDDLEDSPPSLPQHTYWEEQGFKGHFL
                     SAPRAGPSGRRLVPSEAETSPNPSSLGESSTCSPAASSIWEEASQAAGEHWQRQEPPG
                     PNPWASPGPTGLTRREDMTHGLTWEAEGSDPSDFRALSPRGILLADAAEKPEPPALLE
                     KAAGKPPAVPPKTEKALRRAKKLASKRRKSDQLLEKHTEAWEGKSFTEDTQGTERRPV
                     SPGKGPRPRFPAIRSLPPPTHRHSVSCGWEPTGRRPWGPQSLTPLPPYPATQKVLQDP
                     QSGQYFVFDVPLQVKIKTFYDPETGKYVKVSVPSSEEASSEPPLQDALAAPYLLYPGF
                     RPVPVTSVMPLRCSSQLAAPTFLRQGSGHRPQSSQGSRLQPPPERLGESTQHASGQCP
                     RGPSHSPEKESAEAPRLSIISTDDLEDFATEGVS"
ORIGIN      
        1 gtttggtttc cccaggccag tctctgcctg ggtaagcttc tgagacttcc acgtctagca
       61 gtttctggcc actgattttt ttgcccaagt gggaaacctg gtgagacttg ggcagtttga
      121 gtgctgaatc ctctttcttc tcctctctgg gcagcctggc taaaggggaa gaagtttggg
      181 caactgggca gtgccgtgta ccctccagat cccaggaagg cccgtgaaat ctgcagctgg
      241 gacgctcgca cgggagacgg aagatggaag atgggcagtg atgacagcaa atctcagcac
      301 gcaaacatgt ttgaaaaaca cagatcctaa aagccaggcc cctgcagccc cactgccgta
      361 acagggatca tccagaattg aagaaatcct ctgaataaag ctggtgcgca gaagccatgt
      421 gggtttttcc tgagcatcag tgagcatctc ccctgtctgt gtggaaccac actgaaccca
      481 agatcagaga gaaaaaagaa catccagctg ccattgtaac taactggtca tctcaaagcc
      541 ccaccttggg acaggtgggt ttctcttaac cctcaccggc atctcacaga accgcaccta
      601 acagctgaca gacacgtcca aacagaagct gacggagaca gtcctacgga agctgacaga
      661 tgatgcaggg aaacaaaaaa tgcacagacg ggttcagtga tacctccagc atcggcagtg
      721 tgctggatga agcagacagg gaggtgagca acctcacaga cagggcattc cgaagtctgt
      781 gcatctcgga ggacacatcc ttccatgact ctgacctggc cctgtcccca gatgtcacca
      841 gccaggtgtc ggggactttt caccaggaaa cagtgggcca tgccaacagg aaaagtggga
      901 tttggagcca gcttccatct caaggcacag agcattctgg ctgggcagcc accttccaac
      961 agcaacccaa gtacgttcag ggcgaagaaa agtaccccaa aaccagtcct ctgccaaccc
     1021 cagtccagag gagactggag gtgcccattt caggcttgag gagcagcagc aaacccatct
     1081 ccaaagtctc atcactcatt agatcctttg acaggacaga gactcaatct tgtgacagcc
     1141 ggcctcctcc cagcaagcct ccggctctca aaaatccccc caagtttgca catcccccag
     1201 aaagtggtgt caacttctgc ttcgattcgg cctttctgac cgtcaggagg gtgcctgctg
     1261 aagtctccaa cacccatcag ggcagccatc agtctggcag ggctcctgga gaacaagagt
     1321 ctcccaagaa cccagaaata gcctctcaca gctcagacag cctcctccgg acacctgacc
     1381 atgtggctgg ctcatttgag ccaaggtatc cctctccacc tctcaagcca gccacagctg
     1441 agccaggaag agggaaggag tggattccaa ggaggacttt tctgcacagt gaaaacagtg
     1501 cctttgagtc gtgggacacc caccaaccaa agctccggga gagaaaggac attgctgaaa
     1561 ccaccccaga aagcaaagcc cccaaacatt atgaagacat gcctttgcta aaggagccct
     1621 accctgcaga gtccaaaggc tccccctacc aggcccgagc taactgtgcc caggaagaga
     1681 acaggtcacc gtcagggagc caatccacat ctggagcctg gggtgccagg gatccaggat
     1741 cccagctatt ccctgtagag gggaatgctt cacagattga ccctcaggtg aagcggagta
     1801 aggccccatg gaggaagcca aagactggca aaggagggac agatggtcca cctgatgctt
     1861 tggaagacaa gaaacagccc aataggagag gtctacctct gtattcaaaa cttaaccctc
     1921 agggtcaact tccagaaaac ggtgttctag acatgccaga agagtccaat gaccattaca
     1981 atcccccttt taacatcagc aaactcctca ccccaattat atctacaaag catgtcctgg
     2041 aaacttcaga cacccaacca gtggaaataa gcccatcccc tccaggacag ctaaatggat
     2101 accaggagaa ggagtccagt gaggctcagt ctcgggatag ctacaaatcc aaagcgccca
     2161 gcctgctgtt caacctaaaa gatgttcgga aacgtgtcaa gagtacatac agccccttgc
     2221 ctctcttaaa aggctttgat gagaaaacca gaggtaaact tgatagcaag caagaacctc
     2281 tgagcaatgg ggtcaccctt cccgatgggc ttgaagaaaa ccctcccaca gagctcttgc
     2341 cagataatgt ccctggtgtt ttgcacagca gcacccagaa ggatcctgct atcaactcta
     2401 gagaatcctt tgcagtcagc cacccgacct tcagttcacc ttcagctagc tcccaaaccc
     2461 acttctgtgt caatggggaa gctgcagaaa gtaacagtaa tgagaaggaa gaagccaacg
     2521 gagagtcaga gctggatccc tccaagggtg gcgggcatcc agactgcagg gaaaaccttc
     2581 ctcggaaaca tctctccctg aaactcttca acagggagtc tgaaatggga ccggctatgg
     2641 cggaaatgaa gccccaccag ctagagaatg ggctctcgag atctgtctcc caggagacag
     2701 agactgagcg agaaacgggg ttccagagtc tacccttgaa ccagaagttc tccccaggac
     2761 ccctttcccc tgaggaggag gatgtgtttt acagcgacag ccagtctgat tttactccgt
     2821 gccgccaaac aaaggctaaa ttcagcacca gctcctcaga ccaatccttt gcttcttttg
     2881 aagatcagca gaaggtatgc tttacagaag gcccccagga agacaggaag agccatgtga
     2941 gtgcaggtga caagcagagg gacgagacgg cggtggagaa agaagagtca cagcaatgtg
     3001 cctcacgtaa tgaacacaga ggtgtggacg agcagagaca ggaggaaata caaagaaaag
     3061 cacaaggtgt ttcaggagga agacccagga aagcatccgc agaggacctc agtgccagag
     3121 gctcgtggat gggggctgat aaggacacag ctcatacaca cgccaaggac ccaaccccct
     3181 tgccagcctc taccaacaag cacagactgt tcccaattaa agacaacaca ctcagggcca
     3241 ccccggtgat aaagcctatt attctgcctc tcctgaggac agtctcctca gaggactcac
     3301 tgagcagtgg acaccaagag aatgaattgc caaagcaact gtggggcgaa gatgctggcg
     3361 gccttagtgc ttcagaaagc caagaaatgc ctaacacccc actctccaat aacgacgtgc
     3421 cgggcaccca gcacaggtgt atggtgtgtg aggacgtgca ggaagacccg gtacacaccg
     3481 cagcccagga tgagacttct cagcaaaccc ggaaggggag tttctctttt ctaccaccgg
     3541 tggaagagga aaacagaatg aaaccatccc cagatacggc aggtgaaggg ctagcacaag
     3601 agaaaagcaa atcagcagac ttggggaaac tgggggttcc acagcgtatc cccactatcg
     3661 ctttactccc ggatgactta gaagactcgc ccccatcgct accacaacat acctattggg
     3721 aagaacaagg tttcaaaggc cactttttgt ctgcaccgag agcaggaccg tctggaagaa
     3781 ggcttgtccc cagtgaggca gagacttccc ccaaccccag ctctctagga gagagcagca
     3841 cttgctctcc cgcagccagc agtatttggg aagaggcttc ccaggccgct ggggaacact
     3901 ggcagcgcca agagcctcct ggccccaacc cctgggccag cccgggccct acggggctaa
     3961 ctcggaggga ggacatgacc catggcctca catgggaagc tgaaggttcg gatccctcag
     4021 atttcagggc cctctctccg agaggcattt tgctagctga tgctgctgag aaacctgagc
     4081 cccctgctct gctggagaag gcggcaggca agccccctgc agtccctccc aagacggaga
     4141 aggccctgcg cagggcgaag aagctggcaa gcaagaggag gaagagtgat cagttgctgg
     4201 agaagcatac ggaggcctgg gagggcaagt ccttcacaga ggacactcag gggacagagc
     4261 gaaggcctgt gtctcctgga aaggggcctc ggcccaggtt ccctgccatt cgctccttgc
     4321 ccccgcccac gcaccgccac tcagtgtcct gtggctggga gcccacaggg aggcggcctt
     4381 ggggacccca gtccctcacg cctcttcccc cttaccccgc cacccagaag gtgctccagg
     4441 atccccagtc aggacaatac ttcgtcttcg acgtgcctct ccaagtgaaa atcaagactt
     4501 tctatgaccc tgagactggc aagtatgtca aggtctctgt cccatcctct gaggaggcct
     4561 cctcagagcc acctctgcag gatgccctgg ctgctcccta cctactgtac cccggcttcc
     4621 ggccagtgcc tgtgacttcc gtgatgcccc tgcgctgctc ctctcagctt gcagccccca
     4681 cctttctcag gcagggttct ggccataggc cccagagttc ccagggcagt cgactgcagc
     4741 caccccctga acggctgggc gagtctaccc agcatgcctc tggccagtgc ccccgtgggc
     4801 cttcccatag tccagagaaa gagagtgcag aagctccaag actaagtatc atctccacag
     4861 acgacctaga ggactttgcc acagagggtg tttcttgaga attgcagcag actgatctcc
     4921 tccactctca caaacaagaa aggcttacag tcacagaccc tctccaacag tgtatctatc
     4981 tatctatcta tctatctatc tatctatcta tctatctatc tatctatcta tcatctatct
     5041 agacacacat acacacacac acatttcaac tcatacttag ccatttgaga tccctatagt
     5101 ccaaaaagaa ctggggaccc ctgtaggctc cttaaggcca agattcactc ccctcttccc
     5161 agtcatctcg atgcttctct gatcctgcag tggagggggg gggcgcaagg gggagggaca
     5221 tggcacggga catccatcag ccatcctaag attctccttc tcaagggttg gcctcctcaa
     5281 agaagttccc agaaatgctg aaccctgcag caaggtggga agtatcgcgc cacacccaac
     5341 ctggggtcaa gcatagcaca tagcaacaga gttttaggtc ctctcaggtg gcactggcta
     5401 agagcagacc caaggcaatc ttgcagaagt gatcacttgc agagagggtt ttcctcgtgg
     5461 tgggaacttt gtctccaaag aagatcttct gataaagcaa aagttaacat ttaaaatgtg
     5521 aaacaagttt gccagtgtgg tcctgtcaaa aaa
//
