LOCUS       NM_001145676            5052 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus RIKEN cDNA 2210408I21 gene (2210408I21Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_001145676
VERSION     NM_001145676.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5052)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5052)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122418.4, AC099692.4, AC141892.4 and AC158511.2.
            
            On Apr 3, 2023 this sequence version replaced NM_001145676.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151066.1, SRR9219380.50639.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                AC122418.4         83785-83875         c
            92-223              AC122418.4         44431-44562         c
            224-392             AC122418.4         35646-35814         c
            393-1062            AC122418.4         26192-26861         c
            1063-1224           AC099692.4         34947-35108         c
            1225-1319           AC099692.4         26092-26186         c
            1320-1547           AC099692.4         20241-20468         c
            1548-1813           AC099692.4         18155-18420         c
            1814-1964           AC099692.4         16627-16777         c
            1965-2155           AC099692.4         12457-12647         c
            2156-2338           AC099692.4         10365-10547         c
            2339-2449           AC141892.4         162930-163040       c
            2450-2589           AC141892.4         145476-145615       c
            2590-2754           AC141892.4         140622-140786       c
            2755-2979           AC141892.4         127510-127734       c
            2980-3385           AC141892.4         120312-120717       c
            3386-3542           AC141892.4         116059-116215       c
            3543-3698           AC141892.4         111624-111779       c
            3699-3793           AC141892.4         109719-109813       c
            3794-5052           AC158511.2         9569-10827          c
FEATURES             Location/Qualifiers
     source          1..5052
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 40.98 cM"
     gene            1..5052
                     /gene="2210408I21Rik"
                     /note="RIKEN cDNA 2210408I21 gene"
                     /db_xref="GeneID:72371"
                     /db_xref="MGI:MGI:1919621"
     exon            1..91
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            92..223
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..3911
                     /gene="2210408I21Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="uncharacterized protein KIAA0825 homolog isoform
                     1"
                     /protein_id="NP_001139148.1"
                     /db_xref="CCDS:CCDS49316.1"
                     /db_xref="GeneID:72371"
                     /db_xref="MGI:MGI:1919621"
                     /translation="MDALQEYSHNSFDLQCLLNSFPGDLEFKQIFSDIGEQMEQNAAS
                     IEHCIEEIQSEVNKLCPDAQLQTTSDCFKWLTSYNYNLSKSPSISHGDLINFLKTMKD
                     LLNNEDNHEEMILDLLWDLSCQSSISFLSSLGGTTFCHLSRTSIHSVEDFSSVDVKSV
                     WDDVRLHLRRFLVNRLERYNEINNSQQKIELKSQCMKQFLLLYSESEVLVKYQSIQKR
                     LLDTFLQDSFPSCNRESDLERIVCGYQSTMLMLYSMIKEDFNVLCEILAPSSLVQFFN
                     ETYLDTVTEEMTKILEYFCELQFKENAVPVVKTSKSCNKRRGAVHALVSPECSQKERR
                     PSLSLEELRFLSQLTESFVKLENSIQELFAETLSLLQMPRSSPGILEKSKKEVMVEKL
                     IANENNKPPEALLPVKEATLLEFGWRNAFKEVPLAIAHCISAAIEGFSTQVLQQEQTE
                     RTSSVSYTINLVNVPQLCPEGHIFPEEEQPKRVAKFCSDIIEKLDTMLLLALACRDDS
                     PQEIKENLVEAYSKVATAVLERLQERGKEVPSRAPLKNLHSILSSATYVSQRFTHYDN
                     LMKETTKKPIFLVPVQRYQEFINTVQFQVTDYCARVCAMSILQDAESHHWDDYKAFYE
                     GERCSFAIQMWHYFSLALHHDLWTILPPKLAQEILAEMLEKSLGLLASRYARAHPSPK
                     RTAQIRLDVMAILIFTENMLWSICSSGQEILNPHKFNNHKIFKIHTHCNNLFTTLAIL
                     TSPLTELYKTFQHGVDESPSNSLTPLFNQPLHWISCMSQFYPSLLRPPSVGGLTAQGQ
                     LKLLLSQPCCKWNLLLDTLLHSGGLIPRILLKSSKQAAGMESKQSAGGSLVGAIFEVL
                     YHCHLSSQTFGNVFMSHMEEEQLWDFLFNIPVSSFTESQPEVIHCLRLALMDSVKDTV
                     QQIISIMRCRRNSETNLNKPRVPDHLLQSIPQGWNYIPRDSRGKESNKGITELAAQAV
                     SIVLSKLPTVIACLPPTIKYFFFLSERKMSKNLAELKKAGLLVWNLIIIICRIFEDGN
                     TVERLTGSSLDRWSKEKLGLICLCLESILGKQSNPSQLTQKVILSIERQKPNWMEQQL
                     LKARTLSIQCAFTRMEENSGSEGEAALELTEQKTNAMVLDLCHKPGGSKYLQQIYHIM
                     QLNEEYLKEQLFAMNGSEEKPLLIRPLKVALRDEDQPPAFNPFHVHKVVSESMLDQVA
                     TVTWCCDWSNLLPNYLGLNKMTFGALFKNRWEMRKDETLEEKEKMMLEHLKQNCTIQD
                     FSTSDSKTEQ"
     exon            224..392
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            393..1062
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1224
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1319
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1547
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1813
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1814..1964
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2155
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2338
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2339..2449
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2450..2589
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2590..2754
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2755..2979
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2980..3385
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3386..3542
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3543..3698
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3699..3793
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3794..5052
                     /gene="2210408I21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4033..4038
                     /regulatory_class="polyA_signal_sequence"
                     /gene="2210408I21Rik"
                     /note="hexamer: AATAAA"
     regulatory      4041..4046
                     /regulatory_class="polyA_signal_sequence"
                     /gene="2210408I21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4050
                     /gene="2210408I21Rik"
                     /note="major polyA site"
     polyA_site      4070
                     /gene="2210408I21Rik"
                     /note="major polyA site"
     regulatory      5032..5037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="2210408I21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5052
                     /gene="2210408I21Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagcggtcgc cagggctgcc tgagatgccg actatttggt tctggccagc gcgtcaggcc
       61 cttgcaggat cagcgccata gacggagatt gaatggatgc attacaggaa tattcccata
      121 attcatttga cctgcagtgt ctgttaaatt cgtttcccgg agatttggag tttaagcaga
      181 tcttcagtga cattggagaa cagatggagc aaaatgctgc aagtatagaa cattgcattg
      241 aagaaataca gtctgaagta aacaagctct gtccagatgc acagctacaa acaacaagtg
      301 actgcttcaa atggctaact agttataatt ataatttatc taagtcacca tccatttccc
      361 atggagattt aataaacttc ctcaaaacaa tgaaagattt attgaataat gaagacaacc
      421 atgaagaaat gattctggat ttactctggg acctctcctg tcaaagcagc atctctttcc
      481 tgtcctctct gggtgggaca accttctgtc acctgtccag gacttccata cattctgttg
      541 aagatttctc ctctgtggat gtcaagtctg tttgggatga tgtaagatta catcttcgac
      601 gattcttagt aaacaggtta gaaagatata atgagataaa caattcacag caaaaaattg
      661 aactgaaaag tcaatgtatg aagcaattcc tcttgctcta ctcagaatca gaagtgcttg
      721 tcaagtacca aagcatccag aagagactgc tggatacatt tctgcaagac tcctttcctt
      781 cgtgcaacag agaatcagat ttagaaagaa ttgtgtgtgg ataccaaagt actatgctca
      841 tgttatattc aatgataaaa gaggatttta atgtactatg tgaaatttta gctccatcat
      901 cactggtgca gttctttaat gaaacttacc tggatacggt tacagaagaa atgacaaaaa
      961 ttcttgaata tttttgtgag ctgcagttca aagaaaatgc tgttcctgta gttaaaacaa
     1021 gcaagagctg caacaagcgc agaggagcag tgcatgcttt ggtcagccct gaatgctcac
     1081 agaaggaaag acgcccttct ctatccttag aagaactcag atttttatca cagctaacag
     1141 aatcctttgt gaagctggaa aacagcattc aggagctgtt tgcagaaaca ctttcattgc
     1201 ttcagatgcc caggagttct ccaggaatat tggagaaatc taagaaggaa gtcatggtag
     1261 agaagcttat agcaaatgaa aacaataaac caccagaggc attattacca gtaaaagagg
     1321 ctactttact agagtttggc tggagaaatg cttttaaaga agtgcctctt gccatagcac
     1381 actgcatatc tgcagccatt gaagggtttt ccactcaagt tctccagcag gaacaaactg
     1441 aaaggacctc atctgtgagc tacactataa accttgtaaa tgtcccacaa ctttgtccag
     1501 aaggtcacat atttccagag gaggagcaac caaagagagt tgccaagttt tgttctgaca
     1561 tcatagaaaa gcttgataca atgcttctcc tggccctggc atgccgagat gattctcctc
     1621 aggaaatcaa agagaacctg gtagaggcct acagtaaagt ggcaacagct gtcctggaaa
     1681 gactgcagga gagaggaaag gaggttcctt cccgagcacc actgaagaac ctgcacagca
     1741 tcctgtcctc agcaacgtat gtctctcagc ggttcactca ctatgataat ctgatgaaag
     1801 agacaactaa gaaacccata ttcctggtgc ctgtccagcg ctatcaggaa ttcatcaaca
     1861 ctgtccagtt tcaggttacg gactactgcg ccagagtttg tgctatgagc attttacagg
     1921 atgctgagag ccaccactgg gatgactaca aagcttttta tgagggggaa agatgctcct
     1981 tcgccatcca gatgtggcat tacttcagct tggctctgca tcatgatctc tggaccatac
     2041 tgccccctaa gctggcccag gagattctag cagagatgct ggagaaatcc ttgggtctac
     2101 ttgcctccag atatgctcgg gcccacccca gtcctaagag aactgcacag ataagacttg
     2161 atgtcatggc aatcttaata ttcactgaga acatgttatg gtccatttgt tcttctggac
     2221 aggaaatttt gaatcctcat aaatttaaca accataaaat ttttaaaatt catactcatt
     2281 gcaacaatct ctttacaaca ttagcaattt tgacatcacc attaaccgaa ttatataaga
     2341 cttttcagca tggtgtcgat gaatcacctt caaattcctt aactccattg tttaaccagc
     2401 cattacactg gatttcatgc atgtcacagt tctacccttc tctcctcagg cctccatcag
     2461 tgggtggact gacagcccag ggtcagttga aactgctctt atcgcagcct tgctgtaagt
     2521 ggaaccttct tctggacacc ctgcttcaca gtggcggcct cataccgaga atcctgttga
     2581 aaagttcaaa acaagctgct ggcatggaga gtaagcagag tgcaggtggt agcctggtgg
     2641 gcgccatctt tgaagttctg taccattgtc atttgtcctc acagacattt ggaaatgttt
     2701 ttatgagtca catggaagaa gaacaactat gggacttttt attcaacatt ccagtctcat
     2761 cgttcacaga gtctcagcca gaagtcatcc actgtctgag actggcactg atggactctg
     2821 taaaggacac tgtgcaacag ataatatcca tcatgagatg tcggagaaac agcgagacaa
     2881 acctaaacaa gccccgtgtt cctgatcatc tgcttcagag cattccacaa ggatggaatt
     2941 atatcccaag agattccaga gggaaagagt caaataaagg catcacggag cttgctgctc
     3001 aggcagtgtc tattgtcctc agcaagttac ctacagtgat tgcatgcttg cctcccacaa
     3061 ttaaatactt cttttttctg tctgagagaa aaatgtcaaa aaatttggct gaattgaaga
     3121 aagctggcct gcttgtctgg aacttgatta taattatatg tcggatattt gaggatggga
     3181 acaccgtgga acgtttaaca ggttcctccc ttgacagatg gagtaaggag aaactgggtt
     3241 taatttgctt gtgtttggaa agtatcctgg gaaagcaaag caatcctagt cagctgaccc
     3301 aaaaggtcat cctgagcatc gagcggcaaa aacccaactg gatggagcaa cagcttctga
     3361 aagcaaggac actgagcatc caatgtgcat tcacgaggat ggaggaaaac tcaggctcag
     3421 aaggagaagc tgctcttgaa ctgactgagc agaaaacaaa tgcgatggtc ctggatctct
     3481 gccacaaacc aggtggcagc aagtacctgc agcaaattta tcacatcatg cagctcaatg
     3541 aggaatattt aaaagaacaa ctgtttgcta tgaatggctc agaagaaaag ccattactca
     3601 tcagaccttt gaaggtagcc ttgagggatg aagatcagcc tcctgctttt aacccttttc
     3661 atgtgcataa ggtggtcagt gaaagcatgc tagatcaggt ggccacagtg acatggtgct
     3721 gcgactggtc aaacttgctg ccaaattacc taggactgaa taagatgacc ttcggtgcac
     3781 tattcaaaaa caggtgggaa atgaggaaag atgaaacact agaagagaaa gaaaaaatga
     3841 tgcttgaaca tttaaaacag aactgtacca tacaggactt ttccacatca gacagcaaaa
     3901 ccgaacagta atctgcagaa aaacagcaac agctttattt taggaaattg tctcatacaa
     3961 tgaaggcttt tcgccctcct cacaaggagg atagagtgca cccaatagtc tctgttttga
     4021 aagaatcaca ggaataaaaa aataaaaggc tccacgtttc ttattttaaa cataagctca
     4081 aattgttttt ttttttccac aatcttttgc cttatatgat aaaattgctg ccatctcgtg
     4141 tttcctttga gttttttttt ttcttttagt atggaagtat ctatgacaac aggcaaaatg
     4201 tttggaagta ttttcctagg gatttcttac ataatatttg gatgttgagt tgattggaat
     4261 ccccctgaaa gtcatctgaa aattacaatt taattttgaa gctatagccc aaatctggat
     4321 cttaattacc tttaatactc atgattgagc cagtcgccac ttaccatata accttttctt
     4381 tacccactct aaatcataac actaaaaagc actgtctagc actgttagca gcatcagtca
     4441 catgcctgtt tgtgatggtt gttgccttcc tcctaaatct cactccattc ttatgcttcc
     4501 acctcctagg ccaagtggct ctaattcagg caactcctgg catccttttg gctcaaccaa
     4561 aaaaaaaatg gtattttctc caaccaaaaa tcatttttct ttcaaaatta ctttcaaaag
     4621 ttatccttct ttatccctca ttatctacaa ggtctgttga ttttattatt tccactgtgt
     4681 gtgcacatac atactagggg ggggtatatg atgtgggagg ggggatgtgc tctattaacc
     4741 tgtctgccaa gtacaattat atgtatttag tatgtccttc ctatcagtgc ctgatattgg
     4801 attgtaaaga aaccaggggc attaaaaata atctgagggt ttcctttatg aaactgaatg
     4861 tggtgctata ggatcattca gtgtgtgagc agttaataaa catactgact aaggagctac
     4921 cattgaaaga actgttgaca aaatgccttg aggacaaatg ggagaaaccc cactgtggat
     4981 catagaccat ctggcaacga acataatggc ttctgatgtt ctcataaacg taataaaatg
     5041 tgtgtgctcc ca
//
