LOCUS       NM_028211               1350 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RIKEN cDNA 2210016L21 gene (2210016L21Rik), mRNA.
ACCESSION   NM_028211 XM_355679
VERSION     NM_028211.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1350)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1350)
  AUTHORS   Liakath-Ali,K., Vancollie,V.E., Heath,E., Smedley,D.P., Estabel,J.,
            Sunter,D., Ditommaso,T., White,J.K., Ramirez-Solis,R., Smyth,I.,
            Steel,K.P. and Watt,F.M.
  TITLE     Novel skin phenotypes revealed by a genome-wide mouse reverse
            genetic screen
  JOURNAL   Nat Commun 5, 3540 (2014)
   PUBMED   24721909
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1350)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1350)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC031162.1.
            
            On Dec 18, 2003 this sequence version replaced XM_355679.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC031162.1, AK135000.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 55.99 cM"
     gene            1..1350
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /note="RIKEN cDNA 2210016L21 gene"
                     /db_xref="GeneID:72357"
                     /db_xref="MGI:MGI:1919607"
     exon            1..154
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..777
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /note="uncharacterized protein C12orf43 homolog"
                     /codon_start=1
                     /product="protein CUSTOS"
                     /protein_id="NP_082487.1"
                     /db_xref="CCDS:CCDS19576.1"
                     /db_xref="GeneID:72357"
                     /db_xref="MGI:MGI:1919607"
                     /translation="MVAPSGAMSDSENSSSSSSDAEELARCREAATPAWGLEQRPGAA
                     ERPEAGAADKQAPTPQPSRRHEVNQHEEDGNDLRTTPEFRAHVAKKLGALLDSSIAIA
                     EVWKKSQKAKMQQVAKEEDGFRLFFTSIPGGHKKEASPRPCRKRQPPSSSEDSDEELQ
                     RCREAAVSASDILQESAIHCPAKAEEKKKLKKKAKKKVDNADLAAAPGLEQVKEAGVV
                     NGDPVSLGIQKKKKKKAKKSREAPLCPPAECAAAKPEN"
     exon            155..197
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /inference="alignment:Splign:2.1.0"
     exon            198..296
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /inference="alignment:Splign:2.1.0"
     exon            297..370
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /inference="alignment:Splign:2.1.0"
     exon            371..461
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /inference="alignment:Splign:2.1.0"
     exon            462..1320
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1292
                     /gene="2210016L21Rik"
                     /gene_synonym="Custos"
                     /note="major polyA site"
ORIGIN      
        1 cccaggatgg tggcgcccag cggtgcaatg agcgattcgg agaacagcag cagtagcagc
       61 agcgatgcgg aggaattggc acgctgtcgc gaggcggcta cgcccgcctg ggggctggag
      121 cagcgcccgg gggcagcgga gagacccgaa gccggtgctg cagataaaca agcaccgacc
      181 ccgcagccaa gccgcaggca tgaggtgaac cagcacgagg aagatggcaa cgaccttcgg
      241 accactcctg agttccgagc ccacgtggcc aagaaactgg gagccctgct ggacagctcc
      301 attgccatcg cagaagtttg gaagaagtcg caaaaggcaa agatgcagca ggtggcaaag
      361 gaggaggatg gcttccgcct tttcttcaca tccatccccg gaggccataa gaaggaagcc
      421 tctccaagac cctgccggaa gcgccagccc cccagctcca gtgaggacag cgatgaggaa
      481 ctgcagcggt gccgggaggc agctgtgtcg gcttcagaca ttctccagga gtcagccata
      541 cactgccctg ccaaggcaga ggagaagaag aagttgaaaa agaaagccaa gaagaaggtg
      601 gacaatgctg acctggctgc agccccaggt ctggaacagg taaaggaggc aggcgttgtc
      661 aatggggacc cggtgtcgct tgggatccaa aagaagaaaa agaagaaggc caagaaatcc
      721 agagaggctc ccctgtgccc accagcagag tgtgcagcgg cgaagcctga gaactgaccc
      781 caagctgtag gtccagccct gaggatcagg tgcccatgga gttagggcag agccaagcca
      841 cactcccagt ttccagcttc ccacaatgac tgcccagggt gactttaggt gggcttggcc
      901 aagagtccaa gcaatggagt gggtgtatga ggagaggcct ggaatagatt tgtggttcca
      961 gaacgttccc cagcttttgg actgaatctc agagcatcca tctccccagc ctgtgcagcc
     1021 ttgcatgaca gttgtcctag agaatgatgg gcaggggtct ccaagctgcc gaggccccag
     1081 aaaaatttta gtacctctcc cccagactta agaacattgt ctggaaaaga agggaaggtc
     1141 tcccccacct cctcctctcc ccacatttgt ctgtaacatg ttgacttgtt aataccacag
     1201 gtaagtcagt cactgacagt caggtgccag agcacctgct tagtgctagg ctgcatgcag
     1261 gcttgggtac aaggccctaa gaaagagaaa aaggaaaata aattctcacg tgtcccaaga
     1321 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
