LOCUS       NM_023707                856 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus RIKEN cDNA 1810009J06 gene (1810009J06Rik), mRNA.
ACCESSION   NM_023707
VERSION     NM_023707.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Hayashi H, Kohno T, Yasui K, Murota H, Kimura T, Duncan GS,
            Nakashima T, Yamamoto K, Katayama I, Ma Y, Chua KJ, Suematsu T,
            Shimokawa I, Akira S, Kubo Y, Mak TW and Matsuyama T.
  TITLE     Characterization of dsRNA-induced pancreatitis model reveals the
            regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5
            gene transcription
  JOURNAL   Proc Natl Acad Sci U S A 108 (46), 18766-18771 (2011)
   PUBMED   22042864
  REMARK    GeneRIF: IFN regulatory factor 2 (Irf2) has a regulatory role in
            trypsinogen5 gene transcription, which is resistant to a major
            endogenous trypsin inhibitor, Spink3
REFERENCE   2  (bases 1 to 856)
  AUTHORS   Chen F, Rowen L, Hood L and Rothenberg EV.
  TITLE     Differential transcriptional regulation of individual TCR V beta
            segments before gene rearrangement
  JOURNAL   J Immunol 166 (3), 1771-1780 (2001)
   PUBMED   11160223
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161768.25.
            
            On Nov 17, 2006 this sequence version replaced NM_023707.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007406.1, BC132243.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849388 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                AC161768.25        121062-121118
            58-220              AC161768.25        122453-122615
            221-474             AC161768.25        122897-123150
            475-611             AC161768.25        123700-123836
            612-856             AC161768.25        124473-124717
FEATURES             Location/Qualifiers
     source          1..856
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 19.02 cM"
     gene            1..856
                     /gene="1810009J06Rik"
                     /note="RIKEN cDNA 1810009J06 gene"
                     /db_xref="GeneID:73626"
                     /db_xref="MGI:MGI:1920876"
     exon            1..57
                     /gene="1810009J06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..761
                     /gene="1810009J06Rik"
                     /EC_number="3.4.21.4"
                     /note="trypsinogen 5"
                     /codon_start=1
                     /product="uncharacterized protein LOC73626 precursor"
                     /protein_id="NP_076196.1"
                     /db_xref="CCDS:CCDS20042.1"
                     /db_xref="GeneID:73626"
                     /db_xref="MGI:MGI:1920876"
                     /translation="MKIITFFTFLGAAVALPANSDDKIVGGYTCPKHSVPYQVSLNDG
                     ISHQCGGSLISDQWVLSAAHCYKRRLQVRLGEHNIDVLEGGEQFIDAEKIIRHPDYNK
                     DTVDNDIMLIKLKSPAILNSQVSTVSLPRSCASTNAQCLVSGWGNTVSIGGKYPALLQ
                     CLEAPVLSASSCKKSYPGQITSNMFCLGFLEGGKDSCDGDSGGPVVCNGEIQGIVSWG
                     SVCAMRGKPGVYTKVCNYLSWIQETMANN"
     exon            58..220
                     /gene="1810009J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            221..474
                     /gene="1810009J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            475..611
                     /gene="1810009J06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            612..856
                     /gene="1810009J06Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacacactg aaaaactatg aagatcatca ccttcttcac ttttctggga gctgctgttg
       61 ctctcccagc taacagtgat gacaagattg ttggaggcta cacatgtccg aagcattcgg
      121 ttccttacca ggtgtctctg aatgatggca ttagccatca gtgtggtggc tcccttatca
      181 gtgatcagtg ggtactgtct gctgctcact gctacaaaag aagactccag gttcgccttg
      241 gtgaacacaa tattgatgtc cttgagggtg gtgagcaatt tattgatgca gaaaagatca
      301 ttcgacaccc agactataac aaggacactg tggataatga catcatgctg attaaattga
      361 agtcacctgc catccttaac tcccaagtat ccacagtctc tctgcccaga tcctgtgcat
      421 ctacaaatgc tcagtgcctt gtttctggct ggggaaatac tgtgagcatt ggtggaaaat
      481 acccagcact ccttcaatgt ctggaagctc ctgtcctctc ggccagttct tgcaaaaaat
      541 cctacccagg ccagattacc agcaatatgt tctgcctggg attcctggag ggtggaaagg
      601 actcctgtga tggtgattct ggtggacctg tcgtctgcaa tggagagatc cagggtattg
      661 tctcctgggg ttcagtctgt gcaatgagag ggaagcctgg tgtttacacc aaagtctgca
      721 actacctaag ctggattcag gagaccatgg cgaacaactg atttctcttg ccttccataa
      781 atcatctatt tcttatccat ttctctttct tcttatgcct gaaatgaggt tgaaataaat
      841 acatttctgc tgctct
//
