LOCUS       NM_021437               1889 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RIKEN cDNA 1700123O20 gene (1700123O20Rik), mRNA.
ACCESSION   NM_021437
VERSION     NM_021437.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1889)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1889)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT009512.6.
            
            On Aug 14, 2009 this sequence version replaced NM_021437.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB041657.1, AK007261.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-950               CT009512.6         94488-95437         c
            951-1889            CT009512.6         90866-91804         c
FEATURES             Location/Qualifiers
     source          1..1889
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 27.89 cM"
     gene            1..1889
                     /gene="1700123O20Rik"
                     /gene_synonym="MNCb-2990"
                     /note="RIKEN cDNA 1700123O20 gene"
                     /db_xref="GeneID:58248"
                     /db_xref="MGI:MGI:1920893"
     exon            1..950
                     /gene="1700123O20Rik"
                     /gene_synonym="MNCb-2990"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1889
                     /gene="1700123O20Rik"
                     /gene_synonym="MNCb-2990"
                     /inference="alignment:Splign:2.1.0"
     CDS             952..1380
                     /gene="1700123O20Rik"
                     /gene_synonym="MNCb-2990"
                     /codon_start=1
                     /product="uncharacterized protein C14orf119 homolog"
                     /protein_id="NP_067412.1"
                     /db_xref="CCDS:CCDS27099.1"
                     /db_xref="GeneID:58248"
                     /db_xref="MGI:MGI:1920893"
                     /translation="MSLESSSTSVPPCFPSVLPSVPDDIASSSPPPMSYITSQEMKCI
                     LYWFASWSGPQRERFLQDLVAKAVPGKLQPLLDALEQLSMSAANRPPCIFECQLRLWD
                     QWFRGWAEQERNEFVRQLEVSEPDFVAKFYQAVAATAGKD"
     regulatory      1858..1863
                     /regulatory_class="polyA_signal_sequence"
                     /gene="1700123O20Rik"
                     /gene_synonym="MNCb-2990"
                     /note="hexamer: AATAAA"
     polyA_site      1888
                     /gene="1700123O20Rik"
                     /gene_synonym="MNCb-2990"
                     /note="major polyA site"
ORIGIN      
        1 gacaacacag acacaaacaa ggagggggtg ggggaagaag gaaggagctt aagacactcc
       61 gggagagtag cgcgcaccct cccattttgg gctcgcgccg ctgccgttaa ggcgggaacc
      121 ggcgttatct ctatcccagc gccagccaca ccaaccaccg tgcgcgtgga tctgcaggct
      181 cgcgctggcg gcctgagaga gctcgcgccg agcccggaca ctgcgcctgc gccgcggcgg
      241 agactcgtct ctaccgggtc cgctcccctc cgacacctcg gcaacgctga cttctcaccc
      301 ctttgagccg cttgaccagg gcactcttct gcccgctctt ggctaggcct cgctgctcca
      361 gtgcggcctt caggtcggtc acccgcagag cctgaagagg cttcccgtcc agagtcacct
      421 cctccagctc cgccatcttg cgtgaggtac tcgggtccgt cccgacggct tcgggcatct
      481 tcggtaattt ccgccaacgc ccttcgaacg gaccggattg gccccgccca ctgccatagt
      541 ctacccctct attaccgctc agaattcccc gggtttctcc ggagctgttc ggtcgtttcc
      601 gtccccacat cggtaccaat cggctttttc catctaccta gcggctggcc cctcccatct
      661 ggctttcagg ctcgtttgtt ttcggcttgc cggggctttg aatcgaatct cttcggaagc
      721 cctcgaatct ggcataccca taatcggaga tattcggcta tctccggacc tgggggccgg
      781 ggcgctgggg cacttgggta tttggggctg gttccggacc ggaagtgcgt gggttactgg
      841 gggctggctc tgcttcgggt tttcaggaaa catggaagag gctcggagag ttggagcagg
      901 agctgaagga ctcttgtgat ctctgggcgt cttccaaggg gaaaaggaag gatgtcactg
      961 gaatcgtctt ccacatcggt gccaccctgc ttcccttctg tgttaccttc agtgcctgat
     1021 gacattgcca gctcttcccc tcctccaatg tcttacatca cttcccagga gatgaagtgt
     1081 attctttact ggtttgccag ttggtcaggt ccccagcggg aacgttttct acaggacctg
     1141 gtcgctaagg cagtgccggg aaagctacag ccactgctgg atgctctgga gcagctcagt
     1201 atgtctgcag caaatcgacc accatgtatc tttgagtgtc agctacgtct ttgggatcag
     1261 tggtttcgag gttgggctga gcaggagcgc aatgaatttg tcaggcagct ggaggtcagt
     1321 gagccagatt tcgtggcgaa gttttaccaa gcagtggctg ctactgctgg taaggactga
     1381 caggcattca aatcaagaag agaatgacat gtgatcacac catgactgta gtgatgactc
     1441 agtgcaagta tgtcacttaa agattcacct gaactgccag ggtagtggtc cgccttttat
     1501 tccagcaccc aggaggcacc ctggtctaca tagcaagttc caggccagcc agcactacaa
     1561 agcgagaccc tgccttaaaa aaattttttt ttgcatgaac ttcctgttga aggctagcac
     1621 tgtttttacc ctagtggtat gtcacctgga ctctctccca ttttagcaaa tctgattatt
     1681 tacaggagat gtctaagtct caagaattta atgactgctt ttgttactat aactaaaggg
     1741 accagtatct tgtaactcaa gcctacagtg ggcccagatg gggctgtttt gccacattta
     1801 ctcaactcta gcataattat gtgatttccc cactgctgga tttcccagcg atgatttaat
     1861 aaatttaagg aaaattgaga gaaagaaat
//
