LOCUS       NM_138581               1253 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RIKEN cDNA 1700088E04 gene (1700088E04Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_138581
VERSION     NM_138581.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1253)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 1253)
  AUTHORS   Southard-Smith,E.M., Collins,J.E., Ellison,J.S., Smith,K.J.,
            Baxevanis,A.D., Touchman,J.W., Green,E.D., Dunham,I. and Pavan,W.J.
  TITLE     Comparative analyses of the Dominant megacolon-SOX10 genomic
            interval in mouse and human
  JOURNAL   Mamm Genome 10 (7), 744-749 (1999)
   PUBMED   10384052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB602239.1, AA008475.1, AK006539.1 and AL589670.21.
            
            On Sep 15, 2005 this sequence version replaced NM_138581.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006539.1, BC116891.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                BB602239.1         4-31
            29-97               AA008475.1         18-86
            98-1149             AK006539.1         79-1130
            1150-1253           AL589670.21        3160-3263
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.7 cM"
     gene            1..1253
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /note="RIKEN cDNA 1700088E04 gene"
                     /db_xref="GeneID:27660"
                     /db_xref="MGI:MGI:1920774"
     exon            1..97
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /inference="alignment:Splign:2.1.0"
     exon            98..209
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..757
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UPF0193 protein EVG1 homolog"
                     /codon_start=1
                     /product="UPF0193 protein EVG1 homolog isoform 1"
                     /protein_id="NP_613047.1"
                     /db_xref="CCDS:CCDS27633.1"
                     /db_xref="GeneID:27660"
                     /db_xref="MGI:MGI:1920774"
                     /translation="MASQERVDSVTKGTGFRRCRKQAGYTPGTCELLRVMMKESKLTN
                     FQQRHIMDTMKRGAPLPLQCNPTSSLRGSPSKKAASAIYLPPILATHSHLRPASLCQA
                     NGAYSREQFKPQATRDLEKEKRRLQNIFATGKDKEERKKVPHVRQEDPAPELDRFDEL
                     VKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALATT"
     exon            210..272
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /inference="alignment:Splign:2.1.0"
     exon            273..455
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /inference="alignment:Splign:2.1.0"
     exon            456..584
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /inference="alignment:Splign:2.1.0"
     exon            585..685
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /inference="alignment:Splign:2.1.0"
     exon            686..1253
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1227..1232
                     /regulatory_class="polyA_signal_sequence"
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /note="hexamer: AATAAA"
     polyA_site      1253
                     /gene="1700088E04Rik"
                     /gene_synonym="ESTJ0827E04"
                     /note="major polyA site"
ORIGIN      
        1 catggtaaca aggagcgatt agtgaggacg ctgacactct agctccttgg agtttctccg
       61 tgcggagggc tctgtcacgc ccaggtcatc gcctaagggc cctcccatgg cttcccagga
      121 aagggtggac tcggtgacca aaggaaccgg gttccgccgc tgccgtaagc aagcaggtta
      181 cacgccgggg acttgtgagc tgctcagagt tatgatgaag gagtctaaac tgacaaactt
      241 ccagcaacgc cacatcatgg acaccatgaa aagaggagcc cctctgcccc tgcagtgcaa
      301 ccctacatcc agcctgaggg gctctccctc caagaaggca gcctcagcca tctacctgcc
      361 tcccattctg gccacccact ctcacctcag gcctgccagc ttgtgccaag ccaatggggc
      421 gtacagtcgt gaacaattca agcctcaggc caccagagat ctggagaaag agaaacgaag
      481 actccaaaat atctttgcca ctgggaagga caaggaggaa cggaaaaagg ttccccacgt
      541 gcggcaagaa gacccagctc cagagctgga ccggtttgat gaactggtga aagaaatcca
      601 agacaggaaa gaattcttgg ctgccatgga ggctctgggg cagggcaggc agtaccgcag
      661 catcatcctg gctgagatct cccagaaact acgggaaatg gaggacattg atcgcaggag
      721 gagcaaggag ctgaggaaag ccctcgccac cacttaaccc aagacaaggg cgggctcacc
      781 cagtgagact gccaacccgg cacaacagcc agaaccagtg cccttcactc tgccacacag
      841 cacccatccc aggcctgccc acccatgggg gctgggccac gccagatcat gacatggctt
      901 tgtcctgtgg catgaaacag tgtcctagtc actgcctggg gatgcagaag ccgcagagta
      961 gtgtcatagc tactgtgttt ctttctctag ggaaaagccc caggcacacc atggcgatgc
     1021 ccaggctcac ccaccttgga catgtgccta agggcaccct ctctgtggct ctcctgatgt
     1081 cacagctggc ctcaggtgct ctgttttgcc tttctgaacc aaaaattaaa catgactctt
     1141 tcctccctta gatctttccc ttaggatcta agtctttgcc ttcttgtagc cttgggcaaa
     1201 tgtttaacca caacaattaa ctggccaata aaacacattt cacttgcccc tga
//
