LOCUS       NM_025601               1343 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RIKEN cDNA 1700029H14 gene (1700029H14Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_025601
VERSION     NM_025601.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1343)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY094048.1, AK006340.1 and AV284229.1.
            
            On Nov 2, 2013 this sequence version replaced NM_025601.2.
            
            Transcript Variant: This variant (1) encodes the longer protein
            (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006340.1, BC049575.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: translation inferred from conservation
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                BY094048.1         2-57
            57-1332             AK006340.1         2-1277
            1333-1343           AV284229.1         238-248
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 6.26 cM"
     gene            1..1343
                     /gene="1700029H14Rik"
                     /note="RIKEN cDNA 1700029H14 gene"
                     /db_xref="GeneID:66501"
                     /db_xref="MGI:MGI:1913751"
     exon            1..303
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..827
                     /gene="1700029H14Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="uncharacterized protein C13orf46 homolog isoform
                     1"
                     /protein_id="NP_079877.1"
                     /db_xref="CCDS:CCDS52488.1"
                     /db_xref="GeneID:66501"
                     /db_xref="MGI:MGI:1913751"
                     /translation="MEKDPAAHRKHRPGPGALPSGITPAYLKAASDGAELQRSRSVGG
                     LHQKGDPPVCIRKLLRKELDSEDQGKDPRSDTDDGTYRVSLEDDRKKGSQDEVEKMDL
                     KCAKMDPEKSDSEASATGEQDDACKGRCISAAEEQHSESTKLDHLLEKQKPSVFVEID
                     LGDHTEEEVITCAIKEEKRLPNIGDLSEDEIRTSWVCCIPYHTKKKAKENSSALEKNH
                     QSSQDKTPLTQPLVELSGD"
     exon            304..355
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            356..518
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            519..566
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            567..617
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            618..682
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            683..761
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            762..946
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1343
                     /gene="1700029H14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1027..1032
                     /regulatory_class="polyA_signal_sequence"
                     /gene="1700029H14Rik"
                     /note="hexamer: ACTAAA"
     polyA_site      1055
                     /gene="1700029H14Rik"
                     /note="major polyA site"
     polyA_site      1326
                     /gene="1700029H14Rik"
     polyA_site      1343
                     /gene="1700029H14Rik"
ORIGIN      
        1 agtgagtgag atcgcgctgg accactttgc tggcagagag gcagggagag gctggcagag
       61 atgcctttgg tctgaggctg tgctggtgac gccctccttc cctctgggtc aggatggaga
      121 aggaccccgc cgcgcacagg aagcaccggc ctgggcctgg cgccctgccc tcaggaataa
      181 cccctgcata cctcaaggcc gccagtgacg gggcggaact ccagaggagc aggagtgtgg
      241 gtggcttgca ccagaagggg gatccaccag tctgcatcag gaagctgcta cgcaaggagc
      301 tagactctga ggaccaaggc aaagacccaa gaagtgacac ggatgacggc acctatcggg
      361 tgagcctaga ggacgacagg aagaaaggga gccaggatga ggtggaaaaa atggacctca
      421 agtgtgcaaa aatggaccca gagaagagtg actcagaggc cagtgccaca ggggagcagg
      481 acgatgcctg caaaggacga tgtatctctg cggctgagga gcagcattct gagtccacga
      541 agctggatca ccttctagaa aagcagaaac catctgtgtt tgtggagatc gacctgggag
      601 accatactga ggaggaggtc atcacctgtg ccatcaaaga agagaagagg ctccccaaca
      661 taggagactt gtctgaagat gagataagga ccagctgggt atgctgcatc ccgtaccaca
      721 caaagaagaa ggcaaaggaa aactccagtg ctttggagaa gaaccatcag tcatctcagg
      781 acaagacccc tctgactcag ccgctagtag agctctctgg ggactaaagg aagacagcct
      841 aggcctggaa tggctccatg atccccgcca tgggcagggc cagagtgaca gcacccaacg
      901 gatacccaag gcaagagacc ctcttccaat ccaaggccaa tcacagccct aggaaccaac
      961 tcttcaggac cagcaggcac tcccgcttcc tggctatcac agaacttaag agccagctaa
     1021 ttgttcacta aaggaaacaa cacaatatga acacatcgct ggagttacaa tgtcgtatgt
     1081 agacaacttc caggccacag ctggagagga gaggggacaa agtcacctca gaactggtcc
     1141 tccctgcacc cacatcctta gacctcaggt cctgggccac agtcctcctt agtacctcta
     1201 ctggaagcct agttctctca ggatgcttgg gtaggtgaac tccccagtca ccttcccatg
     1261 tgacccctca atcacctttc catgtgaccc cacataacac caatcaaagc aaaacaattc
     1321 ctcaaacatc tgaggcctaa gta
//
