LOCUS       NM_182745                786 bp    mRNA    linear   ROD 03-AUG-2024
DEFINITION  Mus musculus RIKEN cDNA 1700028K03 gene (1700028K03Rik), transcript
            variant 1, mRNA.
ACCESSION   NM_182745
VERSION     NM_182745.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Liu,H., Huang,T., Li,M., Li,M., Zhang,C., Jiang,J., Yu,X., Yin,Y.,
            Zhang,F., Lu,G., Luo,M.C., Zhang,L.R., Li,J., Liu,K. and Chen,Z.J.
  TITLE     SCRE serves as a unique synaptonemal complex fastener and is
            essential for progression of meiosis prophase I in mice
  JOURNAL   Nucleic Acids Res 47 (11), 5670-5683 (2019)
   PUBMED   30949703
REFERENCE   2  (bases 1 to 786)
  AUTHORS   Arora,K. and Corbett,K.D.
  TITLE     The conserved XPF:ERCC1-like Zip2:Spo16 complex controls meiotic
            crossover formation through structure-specific DNA binding
  JOURNAL   Nucleic Acids Res 47 (5), 2365-2376 (2019)
   PUBMED   30566683
REFERENCE   3  (bases 1 to 786)
  AUTHORS   Zhang,Q., Ji,S.Y., Busayavalasa,K. and Yu,C.
  TITLE     SPO16 binds SHOC1 to promote homologous recombination and
            crossing-over in meiotic prophase I
  JOURNAL   Sci Adv 5 (1), eaau9780 (2019)
   PUBMED   30746471
  REMARK    GeneRIF: This paper reported the function of this gene in meiotic
            recombination.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134411.7.
            
            On May 2, 2019 this sequence version replaced NM_182745.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006463.1, BY706503.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AC134411.7         115479-115567
            90-183              AC134411.7         119889-119982
            184-277             AC134411.7         124679-124772
            278-446             AC134411.7         126447-126615
            447-525             AC134411.7         126960-127038
            526-786             AC134411.7         128876-129136
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 52.23 cM"
     gene            1..786
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /note="RIKEN cDNA 1700028K03 gene"
                     /db_xref="GeneID:76421"
                     /db_xref="MGI:MGI:1923671"
     exon            1..89
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /inference="alignment:Splign:2.1.0"
     exon            90..183
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..669
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C1orf146 homolog; synaptonemal
                     complex reinforcing element; protein SPO16 homolog"
                     /codon_start=1
                     /product="protein SPO16 homolog isoform 1"
                     /protein_id="NP_877422.2"
                     /db_xref="CCDS:CCDS19504.2"
                     /db_xref="GeneID:76421"
                     /db_xref="MGI:MGI:1923671"
                     /translation="MDERRGKERVQWTTTIIISSSLKSYEIATALENRSHKVRYSDTL
                     ESGSIVFSLSGVAFLLMDAKECMTSAEEIFVTKIEKFINIHQNSFLVLFAPLHGPEEW
                     SLMFRIHQRFLGSNLRILPVHNTVNALDLMCTIAKTTSKPHIDSICYRMITTKAYIIE
                     QSPVWRTLQKIKLSSDSVSADSGE"
     exon            184..277
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /inference="alignment:Splign:2.1.0"
     exon            278..446
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /inference="alignment:Splign:2.1.0"
     exon            447..525
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /inference="alignment:Splign:2.1.0"
     exon            526..786
                     /gene="1700028K03Rik"
                     /gene_synonym="SCRE; Spo16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcatgcact gcggcaaggg cggccctcgg gaagcccagt ccaccgggcg ctagggagga
       61 gcgaagtgca gcagggacct ggcagtcaga ttgggcttat ccagcggcat ggcaatggat
      121 gagcgtagag gaaaagaaag agtacagtgg acaaccacca ttattatcag ctcatctctt
      181 aagagttacg aaattgcaac tgccctagaa aatcgaagcc acaaggttcg gtattctgat
      241 acactggaaa gtggatcgat tgtattttct ctgtctggag ttgcattctt gttgatggat
      301 gctaaggagt gtatgacatc ggctgaggaa atatttgtaa ccaaaattga gaagtttatt
      361 aacattcacc aaaatagttt cttggttcta tttgctccac tccatgggcc tgaagaatgg
      421 agtctcatgt tcaggataca tcagaggttc ttgggcagta acttacgaat acttcctgta
      481 cacaacacag taaacgctct tgaccttatg tgcactatag ccaagactac gtccaaacca
      541 cacatagaca gcatctgcta cagaatgata acaactaaag cgtacatcat agagcagagc
      601 cctgtctgga gaacacttca aaagataaag ttgagtagtg actcagttag tgcagactca
      661 ggagagtgat cacacttttt caaatggagg attagttaaa cttattaact tgtaatgtcc
      721 aaatgtagat ttaagggcgt ctgtatttaa aataatatgt atacaattaa acttatttta
      781 tttggg
//
