LOCUS       NM_027038                939 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus RIKEN cDNA 1700012B07 gene (1700012B07Rik), transcript
            variant 2, mRNA.
ACCESSION   NM_027038
VERSION     NM_027038.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Ge,T., Yuan,L., Xu,L., Yang,F., Xu,W., Niu,C., Li,G., Zhou,H. and
            Zheng,Y.
  TITLE     Coiled-coil domain containing 159 is required for spermatid head
            and tail assembly in micedagger
  JOURNAL   Biol Reprod 110 (5), 877-894 (2024)
   PUBMED   38236177
REFERENCE   2  (bases 1 to 939)
  AUTHORS   Zambrowicz,B.P., Abuin,A., Ramirez-Solis,R., Richter,L.J.,
            Piggott,J., BeltrandelRio,H., Buxton,E.C., Edwards,J., Finch,R.A.,
            Friddle,C.J., Gupta,A., Hansen,G., Hu,Y., Huang,W., Jaing,C.,
            Key,B.W. Jr., Kipp,P., Kohlhauff,B., Ma,Z.Q., Markesich,D.,
            Payne,R., Potter,D.G., Qian,N., Shaw,J., Schrick,J., Shi,Z.Z.,
            Sparks,M.J., Van Sligtenhorst,I., Vogel,P., Walke,W., Xu,N.,
            Zhu,Q., Person,C. and Sands,A.T.
  TITLE     Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap
            screen to identify potential targets for therapeutic intervention
  JOURNAL   Proc Natl Acad Sci U S A 100 (24), 14109-14114 (2003)
   PUBMED   14610273
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK132924.1 and AK005888.1.
            
            Transcript Variant: This variant (2) uses an alternate splice
            junction for its 3' terminus, compared to variant 1, that results
            in a shorter protein (isoform 2) with a distinct C-terminus,
            compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005888.1, BC048675.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                AK132924.1         2-38
            38-939              AK005888.1         32-933
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 72.61 cM"
     gene            1..939
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /note="RIKEN cDNA 1700012B07 gene"
                     /db_xref="GeneID:69324"
                     /db_xref="MGI:MGI:1916574"
     exon            1..209
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..933
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="uncharacterized protein LOC69324 isoform 2"
                     /protein_id="NP_081314.1"
                     /db_xref="CCDS:CCDS48972.1"
                     /db_xref="GeneID:69324"
                     /db_xref="MGI:MGI:1916574"
                     /translation="MSHFNNWKSAQTSQSLTSQDSIRVSHERKSENKNHEELPESHHS
                     SHGQDKEGVWLPGSRTEEAEEDPAAEEGPFLSKTELQKDTQGACDSKVVGQGRELSPP
                     TTKSIRIYDASPFSSYPLQAEKMSPHRRARMARLPQQGPFRHLMDMKAEKRLAGWKER
                     RSRFGDINVHKCYQFGQVFSPFQALATTEMRRLVLPRDLPMSSHRRRINPSSLGDMNL
                     QDSPLSPELTLGNDDGHHEKDKPVSHIKKPLFPPIVKTMKYNDMK"
     exon            210..397
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            398..531
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            532..705
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            706..939
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      914..919
                     /regulatory_class="polyA_signal_sequence"
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /note="hexamer: AATATA"
     polyA_site      935
                     /gene="1700012B07Rik"
                     /gene_synonym="1700069D21Rik"
                     /note="major polyA site"
ORIGIN      
        1 agagtcagga tctaggatgc cagagaaagg atggagagca atctccacaa atcctggggt
       61 tttgtataaa ggcaacggct aagaaggaag gaaatagcaa aacccccgtc aacactgttg
      121 agtctggaca ccatcttgag aatgtcccat ttcaataatt ggaagagcgc ccaaacgagc
      181 cagagcttga cgtcacagga cagcatcagg gtttctcatg agaggaaaag tgagaacaaa
      241 aatcatgaag agcttccaga gagccaccac tcatcccacg gtcaggacaa ggagggagtc
      301 tggcttcctg ggagcagaac tgaagaggca gaagaagacc cggctgcaga ggagggacct
      361 tttctcagta aaacagaact acaaaaagat acgcaaggag catgtgacag caaagtcgtt
      421 ggacaaggtc gtgaattgtc ccctccaaca acaaagagca tccgaatata cgacgcgagc
      481 cccttttctt cttacccgtt gcaggctgag aagatgagtc ctcacagaag ggcacgtatg
      541 gcccgtctgc cccagcaggg ccctttccgg caccttatgg acatgaaggc agagaagagg
      601 ctggcggggt ggaaggaacg ccgtagccgc tttggtgaca tcaacgtgca caaatgctat
      661 cagtttgggc aggtcttctc tcctttccag gctctggcca ccacagagat gcgaaggctg
      721 gtgctgccca gagacttgcc catgagttct cacaggcgga gaataaaccc ttcatccctc
      781 ggtgacatga acctccagga ttcacccctg tctccagagc tgacattggg aaacgatgat
      841 ggccatcatg agaaggacaa gccagtgagc cacattaaaa agcctttatt ccccccaata
      901 gttaaaacaa tgaaatataa cgacatgaaa tgaaattgc
//
