LOCUS       NM_145758                901 bp    mRNA    linear   ROD 16-FEB-2025
DEFINITION  Mus musculus BPTF associated chromatin complex component 1 (Bacc1),
            transcript variant 2, mRNA.
ACCESSION   NM_145758
VERSION     NM_145758.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 901)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 901)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   4  (bases 1 to 901)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK003842.1, AK002491.1 and AA189586.1.
            
            Transcript Variant: This variant (2) uses a different splice site
            in the 3' coding region, compared to variant 1. The resulting
            protein (isoform 2) has a shorter and distinct C-terminus when it
            is compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY703009.1, AK002491.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-131               AK003842.1         1-131
            132-871             AK002491.1         130-869
            872-901             AA189586.1         382-411
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.99 cM"
     gene            1..901
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /note="BPTF associated chromatin complex component 1"
                     /db_xref="GeneID:104457"
                     /db_xref="MGI:MGI:1915609"
     exon            1..131
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..626
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /note="isoform 2 is encoded by transcript variant 2;
                     MLL1/MLL complex subunit C17orf49 homolog; chromatin
                     complexes subunit BAP18; BPTF-associated protein of 18
                     kDa"
                     /codon_start=1
                     /product="BPTF-associated chromatin complex component 1
                     isoform 2"
                     /protein_id="NP_665701.1"
                     /db_xref="CCDS:CCDS48835.1"
                     /db_xref="GeneID:104457"
                     /db_xref="MGI:MGI:1915609"
                     /translation="MTSASTKVGEIFSAAGAAFTKLGELTMQLHPVSDSSPAGAKWTE
                     TEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKTTVKRKVYEDSGIPLPAESPKKGPK
                     KMTSGVLSPPNAPPPSSSSVPEAGVPPIKKQKADVTLSALNDSDANSDLVDVEGLGET
                     PPAKKLNFDQA"
     exon            132..226
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /inference="alignment:Splign:2.1.0"
     exon            227..328
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /inference="alignment:Splign:2.1.0"
     exon            329..516
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /inference="alignment:Splign:2.1.0"
     exon            517..621
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /inference="alignment:Splign:2.1.0"
     exon            622..882
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      861..866
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /note="hexamer: ATTAAA"
     polyA_site      880
                     /gene="Bacc1"
                     /gene_synonym="0610010K14Rik; 1110020A23Rik; Bap18"
                     /note="major polyA site"
ORIGIN      
        1 gggacttcct gcgcgggagc ccgagcggcc ggctgccggg ctctccgtgg tttccagctc
       61 gcgtggtggt ggtggcggcg gagcgtctcc gtgaggaggt gcgcggggcc atgacgtcag
      121 cgtccaccaa ggttggagag atcttctccg cggccggcgc cgccttcacg aagctcgggg
      181 agttgacgat gcagctgcat ccagtctcgg actcttcccc tgccggtgcc aagtggacgg
      241 agacggagat agagatgctg agggctgctg tgaagcgctt tggggacgat cttaatcaca
      301 tcagctgtgt catcaaggaa cggacagtgg ctcagataaa gaccactgtg aagcgaaaag
      361 tgtatgaaga ctccggcatc ccccttccag ctgagtcacc caagaaagga cccaagaaga
      421 tgacgtccgg tgtcctctca cctccaaacg cccctccacc cagcagctcc agtgtccctg
      481 aagctggggt tcctcccata aagaaacaga aggctgatgt gacactcagt gctctgaacg
      541 actccgacgc caacagtgac ctggtggatg tcgaagggct aggagaaact cctccagcca
      601 agaaactcaa ctttgaccag gcctgaccct ggactctggc ctcctcacca cctccgctga
      661 tgctcctctc ctctcctgct gagccttcca cctctgaccc tcattgttca ccctggacct
      721 gtggatcacc tgggactcta agcaaggact gcctgagaga gggtcagagg gctgctggag
      781 ccatccacct cgttcctgat aaccatgtgc cctcgccctt tgacttctgt gtgatggaca
      841 tttttataca gaaaattata attaaaaaag attctctcaa caaaaaaaaa aaaaaaaaaa
      901 a
//
