LOCUS       NM_020883               5868 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens zinc finger SWIM-type containing 5 (ZSWIM5), mRNA.
ACCESSION   NM_020883 XM_046581 XM_941426
VERSION     NM_020883.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5868)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL592294.15, CN429257.1, AB040944.1, BC013836.1, BM711793.1 and
            AL359473.22.
            
            On Nov 22, 2018 this sequence version replaced NM_020883.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB040944.1, SRR1803616.54229.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000359600.6/ ENSP00000352614.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                AL592294.15        135058-135084       c
            28-49               CN429257.1         1-22
            50-5750             AB040944.1         1-5701
            5751-5844           BC013836.1         3875-3968
            5845-5861           AB040944.1         5797-5813
            5862-5865           BM711793.1         278-281
            5866-5868           AL359473.22        22221-22223         c
FEATURES             Location/Qualifiers
     source          1..5868
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.1"
     gene            1..5868
                     /gene="ZSWIM5"
                     /note="zinc finger SWIM-type containing 5"
                     /db_xref="GeneID:57643"
                     /db_xref="HGNC:HGNC:29299"
                     /db_xref="MIM:620132"
     exon            1..850
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     CDS             256..3813
                     /gene="ZSWIM5"
                     /note="zinc finger, SWIM domain containing 5"
                     /codon_start=1
                     /product="zinc finger SWIM domain-containing protein 5"
                     /protein_id="NP_065934.1"
                     /db_xref="CCDS:CCDS41319.1"
                     /db_xref="GeneID:57643"
                     /db_xref="HGNC:HGNC:29299"
                     /db_xref="MIM:620132"
                     /translation="MADGGEREELLSPSPVSPAKRQCSWPSPQAHHPRGSPGAAGGGA
                     GGVGSSCLVLGARPHLQPDSLLDCAAKTVAEKWAYERVEERFERIPEPVQRRIVYWSF
                     PRNEREICMYSSFQYRGGPGAGAAGGAAGASPAEEGPQPPPGAAAPAGSAPGGVAAGA
                     SPGLGAGAGAAGCGGEGLPFRRGIRLLDSGSVENVLQVGFHLSGTVTELATASEPAVT
                     YKVAISFDRCKITSVTCGCGNKDIFYCAHVVALSLYRIRKPDQVKLRLPISETLFQMN
                     RDQLQKFIQYLITAHHTEVLPTAQKLADEILSSNSEINQVNGAPDPTAGASIDDENCW
                     HLDEEQVKEQVKLFLSQGGYCGSGKQLNSMFAKVREMLRMRDSNGARMLTLITEQFVA
                     DPRLTLWRQQGTNMTDKCRQLWDELGALWVCIILNPHCKLEEKSCWLQQLQKWSDLDV
                     CPLEDGNYGHELPNITNALPQSAIHSPDSLSRPRRTVFTRAIEGRELHWQDSHLQRII
                     SSDVYTAPACQRESERLLFNSQGQPLWLEHVPTACARVDALRSHGYPKEALRLTVAII
                     NTLRLQQQRQLEIYKHQKKELLQRGTTTITNLEGWVGHPLDPIDCLFLTLTEACRLND
                     DGYLEMSDMNESRPPVYQHVPVAAGSPNSSESYLSLALEVALMGLGQQRLMPEGLYAQ
                     DKVCRNEEQLLSQLQELQLDDELVQTLQKQCILLLEGGPFSGLGEVIHRESVPMHTFA
                     KYLFSALLPHDPDLSYKLALRAMRLPVLENSASAGDTSHPHHMVSVVPSRYPRWFTLG
                     HLESQQCELASTMLTAAKGDTLRLRTILEAIQKHIHSSSLIFKLAQDAFKIATPTDSS
                     TDSTLLNVALELGLQVMRMTLSTLNWRRREMVRWLVTCATEVGVRALVSILQSWYTLF
                     TPTEATSIVAATAVSHTTILRLSLDYPQREELASCARTLALQCAMKDPQSCALSALTL
                     CEKDHIAFEAAYQIAIDAAAGGMTHSQLFTIARYMELRGYPLRAFKLASLAMSHLNLA
                     YNQDTHPAINDVLWACALSHSLGKNELAALIPLVVKSVHCATVLSDILRRCTVTAPGL
                     AGIPGRRSSGKLMSTDKAPLRQLLDATINAYINTTHSRLTHISPRHYGEFIEFLSKAR
                     ETFLLPQDGHLQFAQFIDNLKQIYKGKKKLMLLVRERFG"
     exon            851..1207
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1356
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1507
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            1508..1687
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            1688..1864
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..2011
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2149
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            2150..2410
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2546
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            2547..2704
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            2705..2868
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            2869..2950
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     exon            2951..5868
                     /gene="ZSWIM5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5827..5832
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZSWIM5"
                     /note="hexamer: AATAAA"
     regulatory      5843..5848
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZSWIM5"
                     /note="hexamer: CATAAA"
     polyA_site      5851
                     /gene="ZSWIM5"
     polyA_site      5868
                     /gene="ZSWIM5"
                     /note="major polyA site"
ORIGIN      
        1 gtcttcgcgt ccgcggcggc caggacaccg cgcgccgcct cacgctaccc tgcaggccgc
       61 ccgcgtctgc cctcgcggcg cgctcccggg cccggccgcg gttccccact cgggccggct
      121 ggctcgcggg ttctctcgcc ccgcccccct cggcgccacc gctgggcgct tgcgcggggc
      181 gcgtggccgt ggccagggtc tccgccgcag cccgagcagc cgccgccgcc tcagtcagtc
      241 agtcagtccc cagcaatggc ggacggaggt gagcgagagg agctgctctc gccgtcaccg
      301 gtctctccgg ctaagcggca gtgttcgtgg cccagcccgc aggctcatca ccctcgcggt
      361 tcgcctgggg cagccggcgg aggggcaggg ggcgtcggca gcagctgcct ggtcctcggg
      421 gcccgccccc acctgcagcc ggattcctta ctggactgcg ccgccaagac ggtggcggaa
      481 aagtgggcat acgaacgggt ggaggagcgc ttcgagcgga tcccggagcc cgtgcagcgc
      541 cgcatcgtct actggtcctt cccgcggaat gagcgggaga tctgcatgta ctccagcttc
      601 cagtaccggg gcggccccgg cgccggcgct gctggcggcg ccgcgggggc ttcgccggcc
      661 gaggaggggc cgcagccacc ccccggggcc gccgctccgg ccggctccgc ccccgggggc
      721 gtcgcggctg gggcatcccc cgggctgggc gcaggggccg gcgcggccgg ctgcggtggc
      781 gaggggctcc cgttccgccg gggcatccgt ctgctggaca gcggctccgt ggagaacgtg
      841 ctgcaagtcg gctttcatct gagtggcaca gtaactgagc tggccactgc ctctgaacca
      901 gcagtgactt ataaagttgc aatcagtttt gatcgatgca aaatcacctc agtgacatgt
      961 ggctgtggga acaaggacat attctactgt gcccatgtgg tagcactctc actctacagg
     1021 atccgtaaac cagaccaagt caaattgcgt cttcctatct ccgaaaccct tttccagatg
     1081 aatagggacc agctacaaaa gtttattcaa tatttaatca cggcacacca cactgaagtt
     1141 cttcctactg cacagaaact ggcagatgag attctatcct ccaactcaga aatcaaccaa
     1201 gtgaatggtg cccctgaccc cacagctggg gccagcattg acgatgagaa ctgttggcat
     1261 ttggatgaag aacaggtgaa agaacaagtg aagctttttc tctcccaggg cggttactgt
     1321 ggctctggaa agcaactcaa ctcaatgttt gccaaggttc gagaaatgct gcggatgaga
     1381 gattccaatg gagcaaggat gctgacacta ataactgagc agtttgtggc tgacccacga
     1441 ctcacactct ggaggcagca aggaacaaac atgacagaca agtgcaggca gctctgggat
     1501 gagctagggg ctttatgggt gtgcataatt ttaaatccac actgcaaact ggaggagaaa
     1561 tcctgctggc tgcagcagct gcagaagtgg agcgacctgg atgtctgtcc cctggaggat
     1621 ggaaactatg gacatgagct gcccaacatc accaatgcac ttccccagag tgccattcac
     1681 agcccagact ccttatccag accaagacga acagtattca ctagagccat tgaggggcgt
     1741 gaattacatt ggcaggatag ccacctacag cgaataatca gcagtgatgt ttatacagct
     1801 cctgcctgcc agcgggaaag tgaaagacta ctctttaatt cccaaggcca gccactgtgg
     1861 cttgagcatg tgcctacagc ctgtgctcga gttgacgccc tgcgttccca tggttatcca
     1921 aaagaggccc tcagactcac agtggccatt attaatactc tgaggttgca gcagcagcgg
     1981 caactggaaa tctacaagca tcagaagaaa gaactgttgc agagaggaac cacaaccatc
     2041 acaaacctgg agggctgggt gggccacccc ctggatccca tcgactgcct gtttctcact
     2101 ttgactgagg cctgccgcct gaatgatgat ggctatctgg agatgtcaga tatgaatgaa
     2161 agcagacccc ctgtgtacca gcatgtacct gtggctgcag gctccccaaa cagcagtgag
     2221 tcctacctgt cattggccct ggaagttgca ctgatgggcc tgggtcaaca gaggttaatg
     2281 cctgaaggcc tctacgcaca ggacaaggta tgccgtaatg aggagcagct cctgagccaa
     2341 ctccaagagc tgcagctgga cgatgagcta gtgcaaacac tgcaaaaaca atgcatctta
     2401 ctgctggaag gaggtccttt cagcggtctg ggagaagtca tccaccgaga gagtgttccc
     2461 atgcatacct ttgccaagta tttgttctca gctctgctgc ctcatgatcc agacctgtcc
     2521 tataaattag ccttacgtgc catgaggtta cctgttttag aaaactcagc ttctgcaggc
     2581 gacacatccc accctcacca tatggtgtct gtggtgccca gccgttatcc tcgctggttc
     2641 acgcttggac acttggaatc acagcagtgt gaactggcct ccaccatgct gactgctgcc
     2701 aaaggagaca ctttgagact ccgaacaatt ctggaagcaa tacagaagca cattcattct
     2761 tcctccctca tcttcaaact ggcccaagat gcattcaaga ttgctactcc caccgacagt
     2821 agtactgaca gcaccctgct caacgttgcc ctggaacttg ggttacaggt gatgcggatg
     2881 accttatcaa cccttaactg gagacgcagg gagatggtac gatggttggt gacctgtgct
     2941 acagaagtgg gtgtgcgggc cctggtgagc atcttgcaga gctggtacac actcttcacc
     3001 cctactgagg ctactagtat tgtagctgcc acagccgtat cccacaccac tatcctgcgc
     3061 ctcagtcttg actatccaca gcgggaggaa ctggctagct gtgctcgcac actggctcta
     3121 cagtgtgcta tgaaggatcc acagagctgt gccctgtcag cccttacact ctgtgagaaa
     3181 gaccacattg cctttgaggc agcctaccag attgccattg atgctgctgc tggtggtatg
     3241 acccattcac agctgttcac catcgcccgc tacatggagc tccgtggcta cccgctacgt
     3301 gccttcaagc tggcctcatt ggccatgagc catcttaacc tggcctacaa ccaggatact
     3361 cacccagcca tcaatgatgt gctctgggct tgtgctctca gccactctct gggcaagaat
     3421 gagctggcag ctctcatccc cctggtggtg aagagtgtgc actgtgccac agtgctttca
     3481 gacatcttac gacgctgcac agtgactgca cctggcctgg ccggcatccc aggccgccga
     3541 agctctggaa agctcatgtc cactgacaaa gctccattgc gccagttgct ggatgccacc
     3601 atcaatgcct atatcaacac tacacactca cgcctaacac acatcagccc tcgccactat
     3661 ggagagttca ttgagtttct aagcaaggct cgggagacct tcctgctgcc ccaggatggc
     3721 cacctgcagt ttgcccagtt catcgacaac ctcaaacaga tctacaaagg caagaaaaag
     3781 ttgatgctgc tggtgcgaga gcgctttggc tgagagagca gatagctcac tgccagagca
     3841 gcctgggttc ccaggtagta tcaggtcagg ccaagggcac tgaaacattt gtccaccctg
     3901 agagaactct gagcacctgt ggatgaggcc aaaggaccac agggctaagg atggggaaag
     3961 tccagctcta gtcgataatg cctaccttgg caagcttctg actacagcct actgttcatg
     4021 gaggagctgg gccctgcaga tcgaccagaa accccacaac atgccacctc atgcccctat
     4081 atcctgcgtg tcctgagcat tggccctgtc tcccttggca aacacagaac actgttccat
     4141 ctcagggatt gcttaaccag agaaacagac acatttgtgg gactgtaaat actatatgtg
     4201 ttgctaatta ttgtaaactt gtaactattt ataattctgc ttctgatttg atgggcactt
     4261 gaagtagctg tgggtaggag gatatgctta ttttctgagg agactcacaa ccatttctca
     4321 ggtttccctt gcagagtgtt tgctggtagc agtggaagag tgggggtgcc aaggagaaaa
     4381 atggccagtt aggatcaacc caagtctagt ctatgcagaa tcccccacct acagacaggg
     4441 catttatagt ccagtggtga gtgagggaca gaggccagga ctggacttag acttttgcct
     4501 cacaaaactg tgaggacatt gaagctcctg cctcacacag cctcttcagg agcctgctga
     4561 acacctgaga aacaagtgca gggagaagat gaaggtctgg gaagccgctg agttcataat
     4621 attcatctac tgtggtcacc tttgtgttag caagtgtgtg gtttcatcta taattgtgtg
     4681 tgtgtatctt tatggctaag tacatgtgtg tatgtacata gatacatctg tgcatgcctg
     4741 tttgtgcaca tatatattta tgtgtatgtg tcagttctat ggctgtgtac ctgtttgaat
     4801 atgtgcacac tggactgtga gtttctacgt gaggatatac acattttgtg tacatgtgag
     4861 gatgcacatc tttgtgcaaa tgcactcatg tttgtgcatg tttagtatgt gtatctgcgt
     4921 acacgagtgc atgtgtataa acatgtttgt atccatgtgt atgcttgtta tccatgcatc
     4981 tgtgtcttta tatgtgtaac tgagcgtatt tctacatgta gggatgtctg tgtattcatg
     5041 tttgaggatc tgcatcaatg tgtccttttt gccagatttc tctttcccat tcctcttaaa
     5101 tctctctcgc cagctaaacg tttgttcccc atctctgtgc ctcctctatt cattctctca
     5161 ccaaacaagc ttctaagcac caatctccct ctgccatcag attggctgct ttagctccat
     5221 agttctcttc tcgcctcata cttgctttct tcccctgcct ttctacctca agcttcctcg
     5281 ccggcttttg tcacagtctc attgctcgct gacttggagg ctagggctgg tctgcactta
     5341 gcctctccct tcctaatttc tagccctagt gggcagtcct gtcttagccc tggctgacct
     5401 ccatagtgta tcatgttcct gctaccttcc tgacccctgt gctcagcctg gaattgttat
     5461 aggaggtagc aagggcactc agaaaagtca gttggaacca gtgtcttggt gtttactgtt
     5521 tcatgtctta gttcctgagt tgggggtggg gtttgatagg gaaggggtgg tatagctaga
     5581 atgtgaacta agaacttctc catctgcttt actttttctt tcttcgacaa actgtcacct
     5641 tttttactcc aaactgacca agaagttgta tttgccattt gtggctactc aagtcttact
     5701 gtccagccaa gggcccctac gtctcagccc aatgggttgg ttaaaaaaaa gagagaagcc
     5761 actctcattt ctgtatcaca gttgcccttt tttagcaagt gtgtgaattc acagtgcttt
     5821 tctatgaata aatcatggat cacataaaag atcatttttc taaaagca
//
