LOCUS       NM_001080456            1806 bp    mRNA    linear   PRI 21-AUG-2024
DEFINITION  Homo sapiens zinc finger and SCAN domain containing 5B (ZSCAN5B),
            transcript variant 1, mRNA.
ACCESSION   NM_001080456 XM_006723189 XM_292723
VERSION     NM_001080456.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1806)
  AUTHORS   Yamada,M., Sugawara,T., Usami,S., Nakanishi,R. and Akustu,H.
  TITLE     Using piggyBac transposon gene expression vectors to transfect
            Zscan5b gene into mouse pluripotent stem cells
  JOURNAL   STAR Protoc 2 (3), 100811 (2021)
   PUBMED   34541557
  REMARK    GeneRIF: Using piggyBac transposon gene expression vectors to
            transfect Zscan5b gene into mouse pluripotent stem cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1806)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1806)
  AUTHORS   Sun,Y., Zhang,H., Kazemian,M., Troy,J.M., Seward,C., Lu,X. and
            Stubbs,L.
  TITLE     ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes
            and extra-TFIIIC (ETC) sites to modulate mitotic progression
  JOURNAL   Oncotarget 7 (45), 72571-72592 (2016)
   PUBMED   27732952
  REMARK    GeneRIF: Data implicate the role of ZSCAN5 genes in regulation of
            Pol III genes and nearby Pol II loci, ultimately influencing cell
            cycle progression and differentiation in a variety of tissues.
REFERENCE   4  (bases 1 to 1806)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC024580.6.
            
            On Jun 16, 2021 this sequence version replaced NM_001080456.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.341419.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000586855.7/ ENSP00000466072.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AC024580.6         193083-193132       c
            51-561              AC024580.6         188018-188528       c
            562-765             AC024580.6         187199-187402       c
            766-916             AC024580.6         186186-186336       c
            917-1806            AC024580.6         185035-185924       c
FEATURES             Location/Qualifiers
     source          1..1806
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..1806
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /note="zinc finger and SCAN domain containing 5B"
                     /db_xref="GeneID:342933"
                     /db_xref="HGNC:HGNC:34246"
                     /db_xref="MIM:620918"
     exon            1..50
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /inference="alignment:Splign:2.1.0"
     exon            51..561
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..1665
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /codon_start=1
                     /product="zinc finger and SCAN domain-containing protein
                     5B"
                     /protein_id="NP_001073925.2"
                     /db_xref="CCDS:CCDS46203.1"
                     /db_xref="GeneID:342933"
                     /db_xref="HGNC:HGNC:34246"
                     /db_xref="MIM:620918"
                     /translation="MAANWTLSWGQGGPCNSPGSDTPRSVASPETQLGNHDRNPETWH
                     MNFRMFSCPEESDPIQALRKLTELCHLWLRPDLHTKEQILDMLVMEQFMISMPQELQV
                     LVKVNGVQSCKDLEDLLRNNRRPKKWSIVNLLGKEYLMLNSDVEMAEAPASVRDDPRD
                     VSSQWASSVNQMHPGTGQARREQQILPRVAALSRRQGEDFLLHKSIDVTGDPNSPRPK
                     QTLEKDLKENREENPGLSSPEPQLPKSPNLVRAKEGKEPQKRASVENVDADTPSACVV
                     EREALTHSGNRGDALNLSSPKRSKPDASSISQEEPQGEATPVGNRESPGQAEINPVHS
                     PGPAGPVSHPDGQEAKALPPFACDVCNKSFKYFSQLSIHRRSHTGDRPFQCDLCRKRF
                     LQPSDLRVHQRVHTGERPYMCDVCQKRFAHESTLQGHKRIHTGERPFKCKYCSKVFSH
                     KGNLNVHQRTHSGEKPYKCPTCQKAFRQLGTFKRHLKTHRETTSQ"
     exon            562..765
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /inference="alignment:Splign:2.1.0"
     exon            766..916
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1806
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1782..1787
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /note="hexamer: AATAAA"
     polyA_site      1806
                     /gene="ZSCAN5B"
                     /gene_synonym="ZNF371; ZNF495B"
                     /note="major polyA site"
ORIGIN      
        1 ggagagcgca tcccagaccg agaaggtcgg aggcagaagc cgggaaggag acttctgaac
       61 aaactgtgaa tatattactg agaagaaaca ggggcagcct gtgtaaatag gtctcaattt
      121 gatactggct actggaagag cttgctcaga ggctgattga aatattctcc agtagatatg
      181 gctgcaaatt ggacactctc atggggtcag ggaggaccct gcaacagccc tgggtcagac
      241 actccacggt ctgtggcgtc cccagaaact caacttggaa atcacgacag gaaccctgag
      301 acttggcaca tgaatttcag gatgttcagc tgcccagagg agtcggaccc catccaggct
      361 ctgaggaaac tcactgagct gtgccatctg tggctgaggc ccgacctcca caccaaagag
      421 cagatcctgg acatgctggt gatggagcag ttcatgatct ccatgcccca ggagctccag
      481 gtcttagtca aggtgaacgg tgtgcagagc tgcaaagacc tggaggacct gctacgaaat
      541 aacagaagac ccaagaaatg gtctatagtc aacttgctcg gcaaagaata tcttatgctg
      601 aactcagatg tcgagatggc tgaagccccc gccagtgtca gagatgatcc gagagacgtg
      661 tccagccagt gggcctcctc tgtgaaccag atgcatccgg ggacaggcca ggcccgccga
      721 gagcagcaga tcctgcccag ggtcgctgca ctgtccagga ggcagggaga ggactttctg
      781 ctacacaaga gtattgacgt aacaggtgac ccaaactctc cgagacccaa gcagaccttg
      841 gagaaggatc tgaaggaaaa cagggaagag aacccaggac tgtcatcccc agagcctcag
      901 cttccaaaga gtcccaatct ggtgagagca aaggagggga aggaacccca gaaaagagcc
      961 tctgtggaaa atgtggatgc tgacacacct tctgcctgcg ttgtggagag agaagctttg
     1021 actcacagcg ggaacagagg agatgctctg aatctgagca gtcccaaaag aagcaaacca
     1081 gatgcctcct ccatttccca agaagagcct caaggagaag ccacacctgt gggcaacaga
     1141 gaatccccag gacaagctga gatcaatcca gttcattccc caggccctgc gggcccggtc
     1201 agtcacccag atggccaaga agccaaggcc ctgccgccct ttgcatgtga cgtgtgcaat
     1261 aaatcattta agtatttttc ccagctaagc atccacagga ggtcacacac aggagacaga
     1321 ccctttcaat gtgatctctg tcggaagcgc ttcttgcagc cctcagacct ccgagttcac
     1381 cagcgagtcc acactggcga gaggccctac atgtgtgacg tctgccaaaa gcggttcgcc
     1441 cacgagtcca ccttacaggg ccacaagagg atccacaccg gggagaggcc gtttaaatgt
     1501 aaatactgca gcaaagtttt cagccacaag gggaacctga acgttcacca gcgcacccac
     1561 tccggagaga agccctacaa atgtcccacc tgtcaaaagg ccttccgtca gctggggaca
     1621 ttcaagcgtc acctgaaaac acaccgggaa accacctccc agtgattcca gagtcaggtc
     1681 cacatcctcc accccaagag acagtgaatg atggtttttc tccaatgtta ccagatgaca
     1741 tatacacata aagcacttgg taggaattgc ccggatgttt gaataaatat ttatcctccc
     1801 ccatga
//
