LOCUS       NM_001322064            2151 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens zinc finger and SCAN domain containing 5A (ZSCAN5A),
            transcript variant 4, mRNA.
ACCESSION   NM_001322064
VERSION     NM_001322064.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2151)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
REFERENCE   3  (bases 1 to 2151)
  AUTHORS   Sun,Y., Zhang,H., Kazemian,M., Troy,J.M., Seward,C., Lu,X. and
            Stubbs,L.
  TITLE     ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes
            and extra-TFIIIC (ETC) sites to modulate mitotic progression
  JOURNAL   Oncotarget 7 (45), 72571-72592 (2016)
   PUBMED   27732952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006116.1 and AC011506.3.
            
            On Oct 11, 2020 this sequence version replaced NM_001322064.2.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.95878.1,
                                           SRR14038197.2323397.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA2148093,
                                           SAMEA2158188 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000683990.1/ ENSP00000507065.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               AC006116.1         39019-39177         c
            160-261             AC006116.1         37621-37722         c
            262-772             AC011506.3         42266-42776         c
            773-976             AC011506.3         41234-41437         c
            977-1127            AC011506.3         40194-40344         c
            1128-2151           AC011506.3         38906-39929         c
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..2151
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /note="zinc finger and SCAN domain containing 5A"
                     /db_xref="GeneID:79149"
                     /db_xref="HGNC:HGNC:23710"
                     /db_xref="MIM:620916"
     exon            1..159
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /inference="alignment:Splign:2.1.0"
     exon            160..261
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /inference="alignment:Splign:2.1.0"
     exon            262..772
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /inference="alignment:Splign:2.1.0"
     CDS             389..1879
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /note="isoform b is encoded by transcript variant 4; zinc
                     finger protein 495; zinc finger and SCAN domain containing
                     5; zinc finger and SCAN domain-containing protein 5A"
                     /codon_start=1
                     /product="zinc finger and SCAN domain-containing protein
                     5A isoform b"
                     /protein_id="NP_001308993.1"
                     /db_xref="CCDS:CCDS12941.1"
                     /db_xref="GeneID:79149"
                     /db_xref="HGNC:HGNC:23710"
                     /db_xref="MIM:620916"
                     /translation="MAANCTSSWSLGESCNRPGLELPRSMASSETQLGNHDVDPEISH
                     VNFRMFSCPKESDPIQALRKLTELCHLWLRPDLHTKEQILDMLVMEQFMISMPQELQV
                     LVMMNGVQSCKDLEDLLRNNRRPKKWSVVTFHGKEYIVQDSDIEMAEAPSSVRDDLKD
                     VSSQRASSVNQMRPGEGQAHRELQILPRVPALSRRQGEDFLLHKSIDVTGDPKSLRPK
                     QTLEKDLKENREENPGLTSPEPQLPKSPTDLVRAKEGKDPPKIASVENVDADTPSACV
                     VEREASTHSGNRGDALNLSSPKRSKPDASSISQEEPQGEATPVGNRESPGQAGMNSIH
                     SPGPASPVSHPDGQEAKALPPFACDVCEKRFTCNSKLVIHKRSHTGERLFQCNLCGKR
                     FMQLISLQFHQRTHTGERPYTCDVCQKQFTQKSYLKCHKRSHTGEKPFECKDCKKVFT
                     YRGSLKEHQRIHSGEKPYKCSKCPRAFSRLKLLRRHQKTHPEATSQ"
     exon            773..976
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1127
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..2151
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2117..2122
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /note="hexamer: AATAAA"
     polyA_site      2151
                     /gene="ZSCAN5A"
                     /gene_synonym="ZNF495; ZSCAN5"
                     /note="major polyA site"
ORIGIN      
        1 aatgtgaatg cgacaagttc ccgatccagg cgtcccgctc tccccggccc cactcgccag
       61 gtcctaccac gatgcctgac tcgtttgcgg ctttgggacc ggttgtaggt ggcttgaccg
      121 tcactagtag acgtttctga gtgtgtcgcg gtcaccatgg ggaggttccc tgctcaagct
      181 ctcttctctt gtctgctgcc atgtgagacg tgcctttgac cttctgccat gattgtgagg
      241 cctccccagc cacgtgaaac tacttctgaa tgaacagtga atctattact gaggaaaacc
      301 agaggaagcc tgtgtagata ggtatcaatt agataccagc tactggaaga gctttctcag
      361 agactgatta aaaaattctc cactagatat ggctgcaaat tgcacatcct catggagtct
      421 aggagaatcc tgcaacagac ctgggttgga gctgccacgg tctatggcat cctcagaaac
      481 tcaacttgga aatcacgacg tggaccctga gatttctcac gtgaacttca ggatgttcag
      541 ctgcccgaag gagtcggacc ccatccaggc tctgaggaaa ctcactgagc tgtgccatct
      601 gtggctgagg cccgacctcc acaccaaaga gcagatcctg gacatgctgg tgatggagca
      661 gttcatgatc tccatgcccc aggagctcca ggtcttagtc atgatgaacg gtgtgcagag
      721 ctgcaaagac ctggaggacc tgctacgaaa taacagaaga cccaagaaat ggtctgtggt
      781 caccttccac ggaaaggaat atattgtgca ggactcagat atcgagatgg ctgaagcccc
      841 ctccagtgtc agagatgatc tgaaagacgt gtccagccaa cgggcctcct cggtgaacca
      901 gatgcgtcca ggggaaggcc aggcccaccg agagctgcag atcctgccca gggtccctgc
      961 attgtccagg aggcagggag aggactttct gctacacaag agtattgacg taacaggtga
     1021 cccaaagtct ctgagaccca agcagacctt ggagaaggat ctgaaggaaa acagggaaga
     1081 gaacccagga ctgacatccc cagagcctca gcttccaaag agtcccacag atctggtgag
     1141 agcaaaggag gggaaggacc ccccaaaaat agcctctgtg gaaaatgtgg atgctgacac
     1201 accttctgcc tgcgttgtgg agagagaagc ttcgactcac agcgggaaca gaggagacgc
     1261 tctgaatctg agcagtccca aaagaagcaa accagatgcc tcctccattt cccaagaaga
     1321 gcctcaagga gaagccacac ctgtgggcaa cagagaatcc ccgggacaag ctgggatgaa
     1381 ttcaattcat tccccaggcc ctgcgagccc agtcagtcac ccggatggcc aagaagccaa
     1441 ggcactgccg ccctttgcat gtgacgtgtg cgagaagagg tttacgtgta attccaagct
     1501 agtcatccac aagagatcac acacaggcga gagactcttt caatgtaatc tctgtgggaa
     1561 gcgcttcatg cagcttatta gcctccaatt tcaccagcga acccacactg gcgagaggcc
     1621 ctacacgtgt gacgtctgcc agaagcagtt cacccagaag tcctacttga agtgtcacaa
     1681 gagaagccac acaggggaga agcccttcga atgtaaagac tgcaagaaag ttttcaccta
     1741 cagggggagc ctgaaggagc accagcgcat ccactccgga gagaaaccct acaaatgttc
     1801 caagtgtcca agagccttca gtcggctgaa attgttaaga cgccaccaga aaacacatcc
     1861 agaagctact tctcagtgat tgcataatcc ggtctatgcc ttctgcacca agaagaagtg
     1921 aatgatattt ttcatcaatg ttatcagatg acatttgaca catgcaaggg cgtctgacac
     1981 acagagggag tgccctagat atgaattgcc aggatgtttg agtaaatatg tgtcctcccc
     2041 actgagcttt gttttctgtt tcattatgtc cattgttttc ttataggttt attttggttt
     2101 gtgttgctgt tcttccaata aacgatcatc ttattagttt tcaatattgt a
//
