LOCUS       NM_001284527            3108 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens zinc finger and SCAN domain containing 32 (ZSCAN32),
            transcript variant 1, mRNA.
ACCESSION   NM_001284527 XM_005255401
VERSION     NM_001284527.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3108)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 3108)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3108)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 3108)
  AUTHORS   Ravasi,T., Suzuki,H., Cannistraci,C.V., Katayama,S., Bajic,V.B.,
            Tan,K., Akalin,A., Schmeier,S., Kanamori-Katayama,M., Bertin,N.,
            Carninci,P., Daub,C.O., Forrest,A.R., Gough,J., Grimmond,S.,
            Han,J.H., Hashimoto,T., Hide,W., Hofmann,O., Kamburov,A., Kaur,M.,
            Kawaji,H., Kubosaki,A., Lassmann,T., van Nimwegen,E.,
            MacPherson,C.R., Ogawa,C., Radovanovic,A., Schwartz,A.,
            Teasdale,R.D., Tegner,J., Lenhard,B., Teichmann,S.A., Arakawa,T.,
            Ninomiya,N., Murakami,K., Tagami,M., Fukuda,S., Imamura,K., Kai,C.,
            Ishihara,R., Kitazume,Y., Kawai,J., Hume,D.A., Ideker,T. and
            Hayashizaki,Y.
  TITLE     An atlas of combinatorial transcriptional regulation in mouse and
            man
  JOURNAL   Cell 140 (5), 744-752 (2010)
   PUBMED   20211142
  REMARK    Erratum:[Cell. 2010 Apr 16;141(2):369. Kamburov, Atanas [added];
            Kaur, Mandeep [added]; MacPherson, Cameron Ross [added];
            Radovanovic, Aleksandar [added]; Schwartz, Ariel [added]]
REFERENCE   5  (bases 1 to 3108)
  AUTHORS   Venkatesan,K., Rual,J.F., Vazquez,A., Stelzl,U., Lemmens,I.,
            Hirozane-Kishikawa,T., Hao,T., Zenkner,M., Xin,X., Goh,K.I.,
            Yildirim,M.A., Simonis,N., Heinzmann,K., Gebreab,F., Sahalie,J.M.,
            Cevik,S., Simon,C., de Smet,A.S., Dann,E., Smolyar,A.,
            Vinayagam,A., Yu,H., Szeto,D., Borick,H., Dricot,A., Klitgord,N.,
            Murray,R.R., Lin,C., Lalowski,M., Timm,J., Rau,K., Boone,C.,
            Braun,P., Cusick,M.E., Roth,F.P., Hill,D.E., Tavernier,J.,
            Wanker,E.E., Barabasi,A.L. and Vidal,M.
  TITLE     An empirical framework for binary interactome mapping
  JOURNAL   Nat Methods 6 (1), 83-90 (2009)
   PUBMED   19060904
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK291213.1 and AY261676.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001284527.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.657176.1,
                                           SRR1803613.114093.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000396852.9/ ENSP00000380061.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2710              AK291213.1         8-2717
            2711-3108           AY261676.1         2630-3027
FEATURES             Location/Qualifiers
     source          1..3108
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..3108
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /note="zinc finger and SCAN domain containing 32"
                     /db_xref="GeneID:54925"
                     /db_xref="HGNC:HGNC:20812"
     exon            1..60
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /inference="alignment:Splign:2.1.0"
     exon            61..613
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..2341
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /note="isoform a is encoded by transcript variant 1; human
                     cervical cancer suppressor gene 5 protein; zinc finger
                     protein 434; zinc finger and SCAN domain-containing
                     protein 32"
                     /codon_start=1
                     /product="zinc finger and SCAN domain-containing protein
                     32 isoform a"
                     /protein_id="NP_001271456.1"
                     /db_xref="CCDS:CCDS66921.1"
                     /db_xref="GeneID:54925"
                     /db_xref="HGNC:HGNC:20812"
                     /translation="MMAAVKSTEAHPSSNKDPTQGQKSALQGNSPDSEASRQRFRQFC
                     YQEVTGPHEAFSKLWELCCQWLRPKTHSKEEILELLVLEQFLTILPEEIQTWVREQHP
                     ENGEEAVALVEDVQRAPGQQVLDSEKDLKVLMKEMAPLGATRESLRSQWKQEVQPEEP
                     TFKGSQSSHQRPGEQSEAWLAPQAPRNLPQNTGLHDQETGAVVWTAGSQGPAMRDNRA
                     VSLCQQEWMCPGPAQRALYRGATQRKDSHVSLATGVPWGYEETKTLLAILSSSQFYGK
                     LQTCQQNSQIYRAMAEGLWEQGFLRTPEQCRTKFKSLQLSYRKVRRGRVPEPCIFYEE
                     MNALSGSWASAPPMASDAVPGQEGSDIEAGELNHQNGEPTEVEDGTVDGADRDEKDFR
                     NPGQEVRKLDLPVLFPNRLGFEFKNEIKKENLKWDDSEEVEINKALQRKSRGVYWHSE
                     LQKGLESEPTSRRQCRNSPGESEEKTPSQEKMSHQSFCARDKACTHILCGKNCSQSVH
                     SPHKPALKLEKVSQCPECGKTFSRSSYLVRHQRIHTGEKPHKCSECGKGFSERSNLTA
                     HLRTHTGERPYQCGQCGKSFNQSSSLIVHQRTHTGEKPYQCIVCGKRFNNSSQFSAHR
                     RIHTGESPYKCAVCGKIFNNSSHFSAHRKTHTGEKPYRCSHCERGFTKNSALTRHQTV
                     HMKAVLSSQEGRDAL"
     exon            614..779
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /inference="alignment:Splign:2.1.0"
     exon            780..874
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /inference="alignment:Splign:2.1.0"
     exon            875..998
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1481
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..3108
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3087..3092
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /note="hexamer: AATAAA"
     polyA_site      3108
                     /gene="ZSCAN32"
                     /gene_synonym="HCCS-5; ZNF434"
                     /note="major polyA site"
ORIGIN      
        1 gccgctgact tccggcccgg aggctgaggg agtttgtgga gtcgcgagtg ctggtgtccg
       61 acatccttca aagttgagcc ctttttttcc gctgtgagtc tctacacatg tctgacactc
      121 tcatgtccca cggattacag aaagacattc cttgcaggag aacatggctt cccagtgatg
      181 tgggaaagat ggactctgat ctccagggta gaagtggcaa ccagagtaag ccagttcgtt
      241 gaagcaaatg atggctgcag tgaagagtac cgaggcacac ccatcctcaa acaaggatcc
      301 cacacagggc cagaaatcag ccctccaggg taacagccct gactccgagg cctcccgtca
      361 gcgcttcagg cagttttgct accaggaggt aactggccca catgaagctt ttagcaaact
      421 ctgggaactc tgttgtcagt ggctgaggcc gaagacccac tcaaaagagg aaatcctgga
      481 gctgctggtt ttggagcagt ttctgactat cttgccagag gagatccaga cctgggtgag
      541 ggagcagcat ccagaaaacg gcgaggaagc tgtggctctg gttgaggatg tacagagagc
      601 tcctggacaa caggttctag attctgagaa ggacttgaaa gtactcatga aggagatggc
      661 ccctttggga gcaaccagag aatcactgag atcccaatgg aaacaggagg ttcagccaga
      721 ggaaccgact tttaagggat cacagagctc acaccaaaga ccaggggaac agtcagaagc
      781 ctggcttgct cctcaggctc ccaggaacct gcctcaaaac acaggtctcc acgaccagga
      841 gacaggtgct gtggtctgga cagctgggtc ccagggacca gccatgcgtg acaacagagc
      901 tgtatccctc tgtcagcaag aatggatgtg cccaggccct gcacaaaggg ccctctacag
      961 gggtgccacc cagaggaagg acagtcacgt ctcgctggca acaggtgtgc cctggggcta
     1021 tgaagagacc aagacgctcc tggctattct tagtagttct caattttatg gaaaactcca
     1081 gacctgtcag cagaacagcc agatctacag ggccatggcg gaaggactct gggagcaggg
     1141 ttttctgcgg accccagaac agtgtcgcac caagttcaaa agcctacagt tgagttaccg
     1201 caaagtgagg agaggccgtg tgcctgagcc ttgtatcttt tatgaggaaa tgaatgctct
     1261 ttcaggctcc tgggcctctg cacctcctat ggcaagcgat gctgttcctg gccaagaagg
     1321 aagtgatatt gaggctggag agctgaatca ccagaatggg gaacccacgg aggtagaaga
     1381 tggcactgtg gatggtgcag acagggatga aaaggacttc aggaatcctg gccaggaagt
     1441 caggaaacta gacctgccag tgctgttccc aaacagactt ggttttgagt tcaagaacga
     1501 gattaaaaaa gaaaatctaa aatgggatga ttcagaggaa gtagaaataa acaaggcttt
     1561 acagagaaag tccagaggag tttattggca ctctgagcta caaaaaggct tggagagtga
     1621 gccaacatca agaaggcaat gtagaaattc tccaggggag agtgaggaga aaaccccatc
     1681 ccaggagaag atgagtcacc agagtttttg tgccagggac aaagcctgta cacatatcct
     1741 ctgtgggaaa aactgctctc agagtgtgca ctctccccac aagccagcgc tcaaactgga
     1801 aaaagtatct caatgtcctg aatgtgggaa aacctttagc cgaagttctt atcttgttcg
     1861 gcatcaaaga atccacacag gcgagaagcc tcacaagtgc agtgagtgcg ggaagggctt
     1921 tagtgagcgc tccaacctca ctgcccacct acgaactcac acaggggaga ggccctatca
     1981 gtgtgggcaa tgtgggaaaa gcttcaacca gagttccagc ctcattgtcc accagaggac
     2041 ccataccggg gaaaagcctt accagtgcat tgtctgtgga aagagattca acaacagttc
     2101 ccagttcagt gctcaccggc gcatccacac tggggagagc ccatacaagt gtgcagtgtg
     2161 tgggaaaatc ttcaacaata gctcccactt cagtgcccac cgaaaaaccc acactggtga
     2221 aaagccttac aggtgttctc actgtgagag aggcttcact aagaactctg ccctcacccg
     2281 tcatcagaca gtacacatga aagcagtact ctcatcacag gaaggaagag atgcgttatg
     2341 agtgtgtcgg taaactgtca gattaagttc ctcaggtcag catgtatgag ctttcttctg
     2401 ctgtggagag atctagccag tccctgactt tgcaacagac ctactgacta ctggatctta
     2461 agacccatgt ctaggaccag gagtcagcat aaggacgctg acctctcctg gctgtgcctg
     2521 tgactccaga gtcctatctt actgtgactt aaagtttgat ggagagaaag ctgtaggatc
     2581 cataaattct accaggaaac cagggtcttc ctgttcctag cactgagaat gggcacccag
     2641 tggtccaaga acactttctg ggctaacata gtcctcacac agggctgaga aagaaagtgt
     2701 ctcctttcct ggaaagcaca tgtaaaagtt aagggcctga atctcttcta aaccaataat
     2761 tgacctctag gcacccaccg taatactgct accttcaggg cagaagacac tgctctttgt
     2821 aacccagcca ccaccaaaaa gcaaacagaa agaaggaagg atggttaagc cattggataa
     2881 tactgaatct gtttccctaa gtgacttaac cttagagcaa gcacaacatc caggttaatt
     2941 ttttgtaaga tttctccttt tattattgcc ctcatcatag ttcctgattg tctcttaaag
     3001 taagtggttt atagacatta ctatttctga taataattta caaactacta taaacaaatt
     3061 tataaacatt actaatttct gatgaaaata aagttgtttc tccctcca
//
