LOCUS       NM_001023560            2685 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens zinc finger and SCAN domain containing 26 (ZSCAN26),
            transcript variant a, mRNA.
ACCESSION   NM_001023560
VERSION     NM_001023560.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2685)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 2685)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 2685)
  AUTHORS   Kim,Y.C., Wu,Q., Chen,J., Xuan,Z., Jung,Y.C., Zhang,M.Q.,
            Rowley,J.D. and Wang,S.M.
  TITLE     The transcriptome of human CD34+ hematopoietic stem-progenitor
            cells
  JOURNAL   Proc Natl Acad Sci U S A 106 (20), 8278-8283 (2009)
   PUBMED   19416867
REFERENCE   4  (bases 1 to 2685)
  AUTHORS   Attar,R.M. and Gilman,M.Z.
  TITLE     Expression cloning of a novel zinc finger protein that binds to the
            c-fos serum response element
  JOURNAL   Mol Cell Biol 12 (5), 2432-2443 (1992)
   PUBMED   1569959
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK095948.1, AL526328.3 and BC013951.2.
            
            On Aug 13, 2020 this sequence version replaced NM_001023560.3.
            
            Transcript Variant: This variant (a) represents the longest
            transcript and encodes the longest isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX537535.1, SRR14038193.2233354.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000421553.7/ ENSP00000481707.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AK095948.1         86-100
            16-907              AL526328.3         1-892
            908-2685            BC013951.2         492-2269
FEATURES             Location/Qualifiers
     source          1..2685
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.1"
     gene            1..2685
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /note="zinc finger and SCAN domain containing 26"
                     /db_xref="GeneID:7741"
                     /db_xref="HGNC:HGNC:12978"
                     /db_xref="MIM:616474"
     exon            1..71
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /inference="alignment:Splign:2.1.0"
     exon            72..557
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..1577
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /note="isoform a is encoded by transcript variant a; zinc
                     finger and SCAN domain-containing protein 26; zinc finger
                     protein 187"
                     /codon_start=1
                     /product="zinc finger and SCAN domain-containing protein
                     26 isoform a"
                     /protein_id="NP_001018854.2"
                     /db_xref="GeneID:7741"
                     /db_xref="HGNC:HGNC:12978"
                     /db_xref="MIM:616474"
                     /translation="MATALVSAHSLAPLNLKKEGLRVVREDHYSTWEQGFKLQGNSKG
                     LGQEPLCKQFRQLRYEETTGPREALSRLRELCQQWLQPETHTKEQILELLVLEQFLII
                     LPKELQARVQEHHPESREDVVVVLEDLQLDLGETGQQVDPDQPKKQKILVEEMAPLKG
                     VQEQQVRHECEVTKPEKEKGEETRIENGKLIVVTDSCGRVESSGKISEPMEAHNEGSN
                     LERHQAKPKEKIEYKCSEREQRFIQHLDLIEHASTHTGKKLCESDVCQSSSLTGHKKV
                     LSREKGHQCHECGKAFQRSSHLVRHQKIHLGEKPYQCNECGKVFSQNAGLLEHLRIHT
                     GEKPYLCIHCGKNFRRSSHLNRHQRIHSQEEPCECKECGKTFSQALLLTHHQRIHSHS
                     KSHQCNECGKAFSLTSDLIRHHRIHTGEKPFKCNICQKAFRLNSHLAQHVRIHNEEKP
                     YQCSECGEAFRQRSGLFQHQRYHHKDKLA"
     exon            558..675
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /inference="alignment:Splign:2.1.0"
     exon            676..2685
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2667..2672
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /note="hexamer: AATAAA"
     polyA_site      2685
                     /gene="ZSCAN26"
                     /gene_synonym="SRE-ZBP; SREZBP; ZNF187"
                     /note="major polyA site"
ORIGIN      
        1 agagctgaca ctcggcgatg agctaagacg ctgtttcaga gcgtttgggt cctctgaggc
       61 cccttgacca ggagtgtctc tgaagataca gtccaaagaa agttctccaa aacaaggaga
      121 acagtctgaa gctggggatg gcaacagcat tggtgagtgc ccattccctg gctcccctga
      181 atctgaagaa ggaggggctt cgggtagtga gggaggatca ctactctact tgggaacagg
      241 gattcaagct gcaaggaaac agtaaaggcc ttggacagga gccattgtgc aaacaattca
      301 ggcagttgcg ttatgaagag accacaggac ctcgagaagc actaagtcgg ctccgggagc
      361 tctgtcaaca gtggctacag cccgagaccc ataccaagga gcagatcctg gagctgctgg
      421 tgctggagca gtttctgatc atcctgccta aggagctcca ggcccgggtg caggagcatc
      481 acccagagag cagggaggac gtggttgttg ttctggagga tttgcagctg gatcttggag
      541 aaacaggaca acaggtggac ccagaccagc caaagaaaca aaaaatactt gtggaggaga
      601 tggcccctct gaaaggagta caggaacagc aggttcggca tgagtgtgaa gttacaaagc
      661 ctgagaaaga gaagggtgag gagacaagga ttgagaatgg gaagcttatt gtagtaacag
      721 actcttgtgg aagagtagag tcatctggga aaatatctga acccatggag gctcataatg
      781 agggctctaa cttggaaagg catcaggcca agcccaaaga gaagattgag tataaatgct
      841 cagaacgtga gcagagattc atccagcact tggacctgat tgaacatgcg agtacacaca
      901 cgggaaagaa actctgcgag tctgatgtgt gtcagagttc cagtcttaca ggacataaga
      961 aagtcctctc tagagagaaa ggtcatcagt gtcatgagtg tgggaaagcc tttcagagga
     1021 gttcacacct cgtcagacat cagaaaatcc atcttggtga gaagccttat cagtgcaatg
     1081 agtgtggcaa agtctttagc cagaatgcag gccttttgga acatctcaga attcatactg
     1141 gagagaaacc ttatctatgt atccattgtg gaaaaaattt taggcgcagc tctcacctta
     1201 atcgacatca gagaattcac agtcaggagg agccctgtga gtgcaaggag tgtggaaaaa
     1261 cctttagtca ggccttactc ctcacccacc atcagagaat ccatagtcac tccaaaagcc
     1321 atcaatgtaa cgagtgtgga aaagctttca gtttgacctc agaccttatt cgacaccaca
     1381 gaattcatac tggagaaaaa cctttcaagt gtaacatatg ccagaaagcc ttccgactaa
     1441 actcacacct tgctcagcat gtaagaatcc acaatgaaga aaaaccctat cagtgtagtg
     1501 aatgtggaga agccttcagg caaaggtcag gtctttttca acatcagaga tatcaccaca
     1561 aagacaaact ggcttgatga ggtgttctct ccttgtagaa catcagagaa ggcacattga
     1621 ctagcaaaca gcactttagg aaaagtcacc gtagcccact gtggcatcag aaaattcttg
     1681 ggggctgagt tggaggctcc ctgcctctat tctctctcct ttgctttcct tgaagtcagc
     1741 tttggaccac aataatttca ctgtagatga tatgctagga tcaaagttaa acagcattct
     1801 tcactgcagg acatctcaga gcatgtaaca taactgcatg attatatact ctaagcaata
     1861 gagagcttca tgactgagta agagttttga agtcagcagt gaatcaagtg cccacagatt
     1921 tgcaggctta agcagaacaa gggaagattg atatttttgg atatgctata gcagctttct
     1981 cctatgaaat aaaactgatg atgtttggaa gtatactact ctcaaaggtg tctttaaagt
     2041 acaggttaat ggtgaacatt ttcccccagt ggcttcacct cattcctccc actggcctta
     2101 ccccttcctt ccccagtgga agcattttca aaagcaaaga taattttcgc tggtgaactt
     2161 cagaacttgc cttcagggtt agcttcatgt aattttacca tttcccatcc ccattcccca
     2221 ccacattatg tcaagattca agttataaat taacgtttta cttagacttt gaaagagatt
     2281 tcatgagtaa tttgaatgaa ccttgctgaa ttaatctgaa tagcaactgt ctgacttgat
     2341 aactccagtg ccagtatagt ggctgctgca tagacactat tcagtaaatg tctgatgaaa
     2401 gaaattggac tttttccctt taatactgat gatgcaattt tgaaatgttg cttgttctgg
     2461 aatacttcgg aagttaaaca ataaagtcag cttggagagg agatcatgat ctttatactg
     2521 tgaatagcag aatgtcacag atgaagaata ttaaaattag gggcgtccac tccaaaacat
     2581 atcaccagag tgacaacttc agccctcagc ctctgcaatc catatatatc ctggtcttgg
     2641 gagtccatag aatactgttt ccttctaata aaggtttcaa acaaa
//
