LOCUS       NM_003904               6539 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens ZPR1 zinc finger (ZPR1), transcript variant 1, mRNA.
ACCESSION   NM_003904
VERSION     NM_003904.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6539)
  AUTHORS   Ellakwa,D.E., Amr,K.S., Zaki,M.E., Refeat,M. and Banksle,H.M.
  TITLE     Zinc finger 259 gene polymorphisms in Egyptian patients with
            metabolic syndrome and its association with dyslipidemia
  JOURNAL   Ir J Med Sci 193 (5), 2313-2323 (2024)
   PUBMED   38985417
  REMARK    GeneRIF: Zinc finger 259 gene polymorphisms in Egyptian patients
            with metabolic syndrome and its association with dyslipidemia.
REFERENCE   2  (bases 1 to 6539)
  AUTHORS   Masjoudi,S., Sedaghati-Khayat,B., Givi,N.J., Bonab,L.N.H., Azizi,F.
            and Daneshpour,M.S.
  TITLE     Kernel machine SNP set analysis finds the association of BUD13,
            ZPR1, and APOA5 variants with metabolic syndrome in Tehran
            Cardio-metabolic Genetics Study
  JOURNAL   Sci Rep 11 (1), 10305 (2021)
   PUBMED   33986338
  REMARK    GeneRIF: Kernel machine SNP set analysis finds the association of
            BUD13, ZPR1, and APOA5 variants with metabolic syndrome in Tehran
            Cardio-metabolic Genetics Study.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6539)
  AUTHORS   Esteve-Luque,V., Padro-Miquel,A., Fanlo-Maresma,M., Corbella,E.,
            Corbella,X., Pinto,X. and Candas-Estebanez,B.
  TITLE     Implication between Genetic Variants from APOA5 and ZPR1 and NAFLD
            Severity in Patients with Hypertriglyceridemia
  JOURNAL   Nutrients 13 (2), 552 (2021)
   PUBMED   33567543
  REMARK    GeneRIF: Implication between Genetic Variants from APOA5 and ZPR1
            and NAFLD Severity in Patients with Hypertriglyceridemia.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6539)
  AUTHORS   Paquette,M., Fantino,M., Bernard,S. and Baass,A.
  TITLE     The ZPR1 genotype predicts myocardial infarction in patients with
            familial hypercholesterolemia
  JOURNAL   J Clin Lipidol 14 (5), 660-666 (2020)
   PUBMED   32807694
  REMARK    GeneRIF: The ZPR1 genotype predicts myocardial infarction in
            patients with familial hypercholesterolemia.
REFERENCE   5  (bases 1 to 6539)
  AUTHORS   Kannan,A., Jiang,X., He,L., Ahmad,S. and Gangwani,L.
  TITLE     ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and
            rescues spinal muscular atrophy
  JOURNAL   Brain 143 (1), 69-93 (2020)
   PUBMED   31828288
  REMARK    GeneRIF: ZPR1 prevents R-loop accumulation, upregulates SMN2
            expression and rescues spinal muscular atrophy.
            Erratum:[Brain. 2020 Mar 1;143(3):e24. doi: 10.1093/brain/awaa007..
            PMID: 32333675]
REFERENCE   6  (bases 1 to 6539)
  AUTHORS   Gangwani,L., Mikrut,M., Theroux,S., Sharma,M. and Davis,R.J.
  TITLE     Spinal muscular atrophy disrupts the interaction of ZPR1 with the
            SMN protein
  JOURNAL   Nat Cell Biol 3 (4), 376-383 (2001)
   PUBMED   11283611
REFERENCE   7  (bases 1 to 6539)
  AUTHORS   Moores,S.L., Selfors,L.M., Fredericks,J., Breit,T., Fujikawa,K.,
            Alt,F.W., Brugge,J.S. and Swat,W.
  TITLE     Vav family proteins couple to diverse cell surface receptors
  JOURNAL   Mol Cell Biol 20 (17), 6364-6373 (2000)
   PUBMED   10938113
REFERENCE   8  (bases 1 to 6539)
  AUTHORS   Gangwani,L., Mikrut,M., Galcheva-Gargova,Z. and Davis,R.J.
  TITLE     Interaction of ZPR1 with translation elongation factor-1alpha in
            proliferating cells
  JOURNAL   J Cell Biol 143 (6), 1471-1484 (1998)
   PUBMED   9852145
REFERENCE   9  (bases 1 to 6539)
  AUTHORS   Galcheva-Gargova,Z., Gangwani,L., Konstantinov,K.N., Mikrut,M.,
            Theroux,S.J., Enoch,T. and Davis,R.J.
  TITLE     The cytoplasmic zinc finger protein ZPR1 accumulates in the
            nucleolus of proliferating cells
  JOURNAL   Mol Biol Cell 9 (10), 2963-2971 (1998)
   PUBMED   9763455
REFERENCE   10 (bases 1 to 6539)
  AUTHORS   Galcheva-Gargova,Z., Konstantinov,K.N., Wu,I.H., Klier,F.G.,
            Barrett,T. and Davis,R.J.
  TITLE     Binding of zinc finger protein ZPR1 to the epidermal growth factor
            receptor
  JOURNAL   Science 272 (5269), 1797-1802 (1996)
   PUBMED   8650580
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC017349.2, CD365951.1 and
            AP006216.1.
            
            On Nov 22, 2018 this sequence version replaced NM_003904.4.
            
            Summary: The protein encoded by this gene is found in the cytoplasm
            of quiescent cells but translocates to the nucleolus in
            proliferating cells. The encoded protein interacts with survival
            motor neuron protein (SMN1) to enhance pre-mRNA splicing and to
            induce neuronal differentiation and axonal growth. Defects in this
            gene or the SMN1 gene can cause spinal muscular atrophy. Two
            transcript variants encoding different isoforms have been found for
            this gene. [provided by RefSeq, Nov 2015].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC017349.2, SRR1660807.259745.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000227322.8/ ENSP00000227322.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1778              BC017349.2         1-1778
            1779-2136           CD365951.1         31-388              c
            2137-2137           AP006216.1         67249-67249         c
            2138-2149           CD365951.1         18-29               c
            2150-6539           AP006216.1         62847-67236         c
FEATURES             Location/Qualifiers
     source          1..6539
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q23.3"
     gene            1..6539
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /note="ZPR1 zinc finger"
                     /db_xref="GeneID:8882"
                     /db_xref="HGNC:HGNC:13051"
                     /db_xref="MIM:603901"
     exon            1..204
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1413
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein ZPR1; zinc finger protein 259"
                     /codon_start=1
                     /product="zinc finger protein ZPR1 isoform 1"
                     /protein_id="NP_003895.1"
                     /db_xref="CCDS:CCDS8375.1"
                     /db_xref="GeneID:8882"
                     /db_xref="HGNC:HGNC:13051"
                     /db_xref="MIM:603901"
                     /translation="MAASGAVEPGPPGAAVAPSPAPAPPPAPDHLFRPISAEDEEQQP
                     TEIESLCMNCYCNGMTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRIQDQGVR
                     YTLSVRALEDMNREVVKTDSAATRIPELDFEIPAFSQKGALTTVEGLITRAISGLEQD
                     QPARRANKDATAERIDEFIVKLKELKQVASPFTLIIDDPSGNSFVENPHAPQKDDALV
                     ITHYNRTRQQEEMLGLQEEAPAEKPEEEDLRNEVLQFSTNCPECNAPAQTNMKLVQIP
                     HFKEVIIMATNCENCGHRTNEVKSGGAVEPLGTRITLHITDASDMTRDLLKSETCSVE
                     IPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLGDSSNPGQTERLQEFSQKMD
                     QIIEGNMKAHFIMDDPAGNSYLQNVYAPEDDPEMKVERYKRTFDQNEELGLNDMKTEG
                     YEAGLAPQR"
     exon            205..366
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            367..457
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            458..528
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            529..615
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            616..738
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            739..786
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            787..853
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            854..924
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1014
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1125
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1212
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1278
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..6539
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1761..1766
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /note="hexamer: AATAAA"
     polyA_site      1778
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /note="major polyA site"
     regulatory      2595..2600
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /note="hexamer: AATAAA"
     polyA_site      2618
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
     regulatory      6513..6518
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
                     /note="hexamer: AATAAA"
     polyA_site      6539
                     /gene="ZPR1"
                     /gene_synonym="GKAF; ZNF259"
ORIGIN      
        1 aggaagccga ggtctgaatt gcgcgtggtg gccatggcgg ccagcggggc tgtggaacca
       61 gggcccccgg gggctgccgt cgccccgtcg cccgccccgg ccccgccgcc tgcccctgat
      121 cacctgttcc ggcccatcag cgccgaggac gaggagcagc agcccaccga gatcgagtcg
      181 ctatgcatga actgttactg caatggcatg acgcgcctcc tgctcaccaa gattcccttc
      241 ttcagagaaa taatagtgag ctccttttcc tgcgagcact gtggctggaa caacacggag
      301 atccagtcgg caggcaggat ccaggaccag ggagtgcgct acactttgtc tgtcagggct
      361 ctggaggaca tgaacagaga agtggtgaag actgactctg ctgccacaag gattcctgag
      421 ctagattttg aaattcctgc ctttagccag aaaggagctc tgaccactgt tgaaggattg
      481 atcacccgtg ctatctctgg cctggagcag gaccagcctg cacgaagggc aaacaaagat
      541 gctacagctg aaagaattga tgagttcatt gtcaaactga aggagctaaa gcaagtagcc
      601 tcccctttca ctctgatcat tgatgatccc tcagggaaca gttttgtgga aaacccacat
      661 gctcctcaga aagatgatgc cctggtgatc acacactaca accggacccg acagcaggaa
      721 gagatgctgg ggcttcaaga agaagcacca gcagagaagc cagaagagga agatctcaga
      781 aatgaagtgc tccagttcag cacaaactgc ccagaatgca atgcccccgc tcagaccaac
      841 atgaagctag tacaaatccc tcactttaag gaggttatca tcatggctac caactgcgag
      901 aactgtgggc atcggaccaa tgaggtgaaa tctggaggag cagtagaacc cttgggcacc
      961 aggatcaccc tccacatcac agatgcctca gatatgacca gagacctcct caagtctgag
     1021 acttgcagtg tggaaatccc agagctagaa tttgaactgg gaatggcagt cctcgggggc
     1081 aagttcacca cactggaagg gctgctgaaa gacatccggg aactggtgac caaaaatcct
     1141 ttcacactgg gcgacagttc caatcctgga cagacggaga gactacagga gtttagccag
     1201 aagatggacc agatcatcga aggtaacatg aaggcccact ttattatgga tgatccagca
     1261 ggaaacagtt acttgcagaa tgtgtatgcg cctgaagatg atcctgagat gaaggtggag
     1321 cgttacaagc gcacctttga ccaaaatgag gagctagggc tcaatgacat gaagacagag
     1381 ggctatgagg caggcctggc tccgcaacgg tagcagtggg tggctcaagg gccagcctcc
     1441 agcgctgctc tttctgtagg ttatttatta gtattggatg aaggcgaagg ctgggagtgt
     1501 ctttcccacc agcccttgcc catggtgggg aggacatctg gtctgagtca gagatctgtg
     1561 cacactttct aaacagcttg tgatgcaagt gtgagcctat tgtgttactt gaccttattt
     1621 tggaagtttt gaattggcct aggaggaaac ccagaaatga accaggggta tgtcatcact
     1681 tttttcatat caagtcctca ccctccttcc acataatgct ctatcctcta aggttggaac
     1741 tctgaagttg gagaaggtgg aataaagtta cacctggagt ttgttgttgg ttttgagtat
     1801 ataaaatact gactttgaac aggaaaggag tctcctgagg ggagaccgag tccagcacaa
     1861 gtgaaggagt taccattgaa atgatgactt tcaaacagca ctggcctctg tattgaccct
     1921 atccttgttt gatatcatgc tgttagaatt cagcctccta aagaaaattt tcccgtgtat
     1981 ctactgtaat ttggggattg cagctggcat ttaattcatt ccttcagcag atgcttgctt
     2041 atctacttta tgccaagcac accacagaac agaggacaaa ataaatctct ttcatggaac
     2101 ttgaagtcta gtggggaaaa atgacaataa acagatcagg aaaacagtac atcagatggt
     2161 gattagtgtc atggaggaat gtaaagcagg gaatggggct gggttgtgca aggaaatggg
     2221 gagtagggaa gatcttctga acaagaaggt gataatttga catttgggca aagctgagga
     2281 ggaggtcagg gagtgagctg tgtgggtatc tgggggaaga gatttcctgg cagagggaac
     2341 tgcaaatgct agagctgtga ggttagagcc agtgggggta cctgatcagt tagccctact
     2401 ctcagttaga aatgttgaaa cacattcatc cagagagaaa ggaggctctc tgcagttctt
     2461 ctgaaagtta aggaccagtg aacactctgc tgcttgggcc ctggacttcc cagccagtgt
     2521 tctttgcact gtagtctcct gcctctcata aacaaaaggt gactcctgtg gtgcagactg
     2581 cagggtattt gttcaataaa gaccagttca ttgattaaga tgttatcaca aaccttattg
     2641 ctttgtgttg caaacttttt tttttttttt ttttggtaga gacagagtct cgcgctgttg
     2701 cccaggctgg agtgcagtgg tgtgatcttg gcttattgca acctttgcct cccgggttta
     2761 agcaattctg cctcagcctc ccgagtagcg gggactacag gcgcacgccg ccacacccag
     2821 ctaatttctt ttgtatttta gtagagacgg ggtttcaccg tgttgcccag gctggtctcg
     2881 aactcctgag ctcaggcaat ccgccagcct tggcctccca aagtgctagg attacaggcg
     2941 tgagctaccg cgtccggctg tgttgcaaac ttaactctga agaatgagtt agagatgatt
     3001 tagcaatcag acatctactc tcgttgctct gttaaactac tctcaaaggt cacaagtgat
     3061 tttccacttg gaaagtgtta tctatttctg tcacatttga tagtggacca tctcttctta
     3121 acccttcttt tggctctcga gatactgtac ccttggtttt cccttcactt tgaatatttc
     3181 ttatttggac actttgcctc ctcccctctt actaaatttg tttctgagag ttctgctttc
     3241 agacatctct ccatatcaga ttctttggca tcttactatc atgtgggact aacttccata
     3301 cctgtatctc taatttctgt aagtgagggc gagagtaagg tgtttggaga ctcaggttag
     3361 caaatgactc attcaaacta taaagcttca gtactttggg caaacttctc acaggcaact
     3421 attctaccct aagagattat ctctaggtat gtttccagct gacttgggaa tctaagttta
     3481 ccagacaacc ctctgatcta tcatttggtc tcttaagtag acttccccat agtgtaggtg
     3541 tgctctgtta agataaactg cagtatcagg ttcattttcc attgtgaagg aaaaaaaatg
     3601 gcactctggc ttattactga atctcttgtg agtttggttg gtgtgaggca atctcccaga
     3661 atccacccag ttcctaggaa atgatgacct gagtttctga acttgaagac tgaggaccag
     3721 gtgccagact gggataaccc agctaaggta cttcctgccc tttgatgaca aggcattctt
     3781 cagtttcata cccttctctt gaattatctt tcagctcctt tctcatttca taaagtgtgt
     3841 caggatggga gcttacatat agttaactga gtcttgctcc acagcaccca gcatatgaca
     3901 catggttaat aaaatctgtt aaaatcctcc atcatagatt aaaccctatt aggacactag
     3961 ggataacatc tataggtaaa aagataggga aagggtctcg ctttaaggcc agggtaggtg
     4021 agtcaaagtg ccaggaacat gtggattcag tttcacagcc atgagtaaca tttaagtgga
     4081 aaaggtttgt gattgtgtta aaaaaggaaa gtggttcatg catgagggca cgcctcctac
     4141 tttcatgggt caagtatgtg aaatgcagcc atgttcggtc attagacgtg tggacgaaca
     4201 tacaggtagg tactgaatgt acatctgtgt catgatgagt ggaggagggg aggtgagtgt
     4261 tgggagcaag tatgaagggc agttgacttg gccaactgaa aactttaatg atggcaacac
     4321 tttcattcta acatcagtat atttccttct ttgtacacct gtggtatgtg cctgatgcac
     4381 actgcagaaa atggtgtctc tgcttacatt tagggcagtg gtggctaaga ctacttggct
     4441 ttattcctat taaaaaatgt tttttacaca cttcttttta aggcaaatgg cagtgtttcc
     4501 aactgtggag agaaaaagct gcttattttg tgcgttcacc tcagtttagt attggcactt
     4561 ccaatgcttg ttttcctagt ctgtaaaatg gggataatta ggataaacaa aattatcccc
     4621 attttacagg tgacaaaaca gcctcagaga ggttacttcc agaaggaagc agagcttttt
     4681 tttttttttt tttttttttt tttttttttt gagacggagt ctcactctgt tgcccagact
     4741 ggagtgcagt ggcgtgatct tggctcacca caacctctgc ctcccaggtt caagcgattc
     4801 tcttgcctca gccttctgag tagctgggac tacaggtgca cgccaccatg cctggctaat
     4861 tttttttttt tttttttttt tggagacagt cttgctctgt cacccaggat ggagtgcagt
     4921 ggtgcgatct tggctcactg cagccttgcc tcctgggttc aagcaattct cctgcctcag
     4981 cctcctgagt agctgggatt acagacgccc accactgcac ccagctaatt tttgtatttt
     5041 tagtagagat ggggtttcac catgttggtc aggctggtct caaacccctg acctcgtgat
     5101 ccacctgcct tggcctccca aagtgcaggg attacaggcg tgagccaccg tgcctggcca
     5161 gaagtagagc ttctaagagg caggtgtcaa acccatgcca gtcagactct gaaacctgag
     5221 gtctgaatat tttaagctca gctccacaat tactgtattt gttctattag atacaactgc
     5281 agagagaggc caaagctcag agcaggccat tggcacggca tctgatcctg cttaactgcc
     5341 ctgcagcaca gggtggagac acttgggcct tgtcaggcta agggactggg gtaggatggg
     5401 tagcagtgga attgaagaca aagaaaacaa atgggcagaa gatgggtggg tggaagttca
     5461 gagggctatc ctggcagtgt tcactggagc agaagtgtga ggctttctga atgcctgctg
     5521 acaccagggt ggggcagggc tgtgtagtgt gagatgcacc aaattggacg agaagccaag
     5581 gcaggcttgt gtatggggta ccctggggcc ctccgcctag tgaagcccta tcttctcagc
     5641 ccagcgtcct cgtctcacaa gccctcagag ccccagcctg ctttcctttc tgggcctgtg
     5701 ctgcaacccc ctcaacatgg cccactgggt aaaaattcat gcttcaagac tgatccccaa
     5761 gcctgttttg tattatatga gtaaagaatt ttttaaacac ttatccccag ataatgtgta
     5821 tttatttata aagtatagcc ctgtctgctt gactaatata ttaaaaaagt gacctttttg
     5881 actcttggtc caagaaacta ttgtttgcac ttttgtgtag ttgtgtatag catcctgcaa
     5941 attctgtcag aagtctgtga tttcagtaac actaaaactt ctctctcaaa tggtacaagt
     6001 tttcagtttt aagacaagtt ctgggaatct aatgtacaac atgttgacta tagctaataa
     6061 ttctgtattg tttacttgaa gtttgctaag acaaatttgc ttaagtgccc ccccaccgaa
     6121 ctactacata aattagtgaa ggatgtttta cttaatttga ttttggtaat cattacacaa
     6181 tgtataatta tatccagtca tcacattgta caccttgaat atatataatt ttttgtcaaa
     6241 taataaagct gggaagaaaa cgataaaact gacaatctaa catatatgat gaggtaaaaa
     6301 gatctggtat ttcaagaaat ttggatgacc tcttgcaccc cacttcgcta gcctctactc
     6361 cctagagtca tgttctgact atgtgaagtt gagcaacttc cttaatcttg ccacgcttca
     6421 gttcttatct gtaaaatatg ataatgaaac gatttgagaa ttgtgagggt taaatgagat
     6481 aattcaggta aagctctaaa ccccctgcaa agaataaagt cttttctttc cccccaaaa
//
