LOCUS       NM_021035               7209 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger NFX1-type containing 1 (ZNFX1), mRNA.
ACCESSION   NM_021035
VERSION     NM_021035.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7209)
  AUTHORS   Wang,Z., She,D., Liu,L., Hua,X., Zhu,H., Yu,L., Wang,H., Zhu,Y.,
            Fan,G., Wang,Y., Xu,M. and Zhou,G.
  TITLE     Circular RNA CircSATB2 facilitates osteosarcoma progression through
            regulating the miR-661/FUS-mediated mRNA of ZNFX1
  JOURNAL   Cell Signal 114, 110977 (2024)
   PUBMED   37984605
  REMARK    GeneRIF: Circular RNA CircSATB2 facilitates osteosarcoma
            progression through regulating the miR-661/FUS-mediated mRNA of
            ZNFX1.
REFERENCE   2  (bases 1 to 7209)
  AUTHORS   Gu,Y., Wang,G. and Xu,H.
  TITLE     Long non-coding RNA ZNFX1 antisense 1 (ZFAS1) suppresses
            anti-oxidative stress in chondrocytes during osteoarthritis by
            sponging microRNA-1323
  JOURNAL   Bioengineered 13 (5), 13188-13200 (2022)
   PUBMED   35635081
  REMARK    GeneRIF: Long non-coding RNA ZNFX1 antisense 1 (ZFAS1) suppresses
            anti-oxidative stress in chondrocytes during osteoarthritis by
            sponging microRNA-1323.
REFERENCE   3  (bases 1 to 7209)
  AUTHORS   Alawbathani,S., Westenberger,A., Ordonez-Herrera,N., Al-Hilali,M.,
            Al Hebby,H., Alabbas,F., Alhashem,A.M., Elyamany,G., Megarbane,A.,
            Kose,M., Alhashmi,N., Al Sukaiti,N., Al-Raqad,M., Al-Tawalbeh,S.,
            Abu Adas Blanco,O., Alkhattabi,F., Sng,D., Al-Ali,R., Khan,S.,
            Tawamie,H., Tripolszki,K., Karageorgou,V., Trunzo,R., Al
            Mutairi,F., Reversade,B., Bauer,P. and Bertoli-Avella,A.M.
  TITLE     Biallelic ZNFX1 variants are associated with a spectrum of
            immuno-hematological abnormalities
  JOURNAL   Clin Genet 101 (2), 247-254 (2022)
   PUBMED   34708404
  REMARK    GeneRIF: Biallelic ZNFX1 variants are associated with a spectrum of
            immuno-hematological abnormalities.
REFERENCE   4  (bases 1 to 7209)
  AUTHORS   Vavassori,S., Chou,J., Faletti,L.E., Haunerdinger,V., Opitz,L.,
            Joset,P., Fraser,C.J., Prader,S., Gao,X., Schuch,L.A., Wagner,M.,
            Hoefele,J., Maccari,M.E., Zhu,Y., Elakis,G., Gabbett,M.T.,
            Forstner,M., Omran,H., Kaiser,T., Kessler,C., Olbrich,H., Frosk,P.,
            Almutairi,A., Platt,C.D., Elkins,M., Weeks,S., Rubin,T., Planas,R.,
            Marchetti,T., Koovely,D., Klambt,V., Soliman,N.A., von
            Hardenberg,S., Klemann,C., Baumann,U., Lenz,D., Klein-Franke,A.,
            Schwemmle,M., Huber,M., Sturm,E., Hartleif,S., Haffner,K.,
            Gimpel,C., Brotschi,B., Laube,G., Gungor,T., Buckley,M.F.,
            Kottke,R., Staufner,C., Hildebrandt,F., Reu-Hofer,S., Moll,S.,
            Weber,A., Kaur,H., Ehl,S., Hiller,S., Geha,R., Roscioli,T.,
            Griese,M. and Pachlopnik Schmid,J.
  TITLE     Multisystem inflammation and susceptibility to viral infections in
            human ZNFX1 deficiency
  JOURNAL   J Allergy Clin Immunol 148 (2), 381-393 (2021)
   PUBMED   33872655
  REMARK    GeneRIF: Multisystem inflammation and susceptibility to viral
            infections in human ZNFX1 deficiency.
REFERENCE   5  (bases 1 to 7209)
  AUTHORS   Le Voyer,T., Neehus,A.L., Yang,R., Ogishi,M., Rosain,J., Alroqi,F.,
            Alshalan,M., Blumental,S., Al Ali,F., Khan,T., Ata,M., Rozen,L.,
            Demulder,A., Bastard,P., Gruber,C., Roynard,M., Seeleuthener,Y.,
            Rapaport,F., Bigio,B., Chrabieh,M., Sng,D., Berteloot,L.,
            Boddaert,N., Rozenberg,F., Al-Muhsen,S., Bertoli-Avella,A.,
            Abel,L., Bogunovic,D., Marr,N., Mansouri,D., Al Mutairi,F.,
            Beziat,V., Weil,D., Mahdaviani,S.A., Ferster,A., Zhang,S.Y.,
            Reversade,B., Boisson-Dupuis,S., Casanova,J.L. and Bustamante,J.
  TITLE     Inherited deficiency of stress granule ZNFX1 in patients with
            monocytosis and mycobacterial disease
  JOURNAL   Proc Natl Acad Sci U S A 118 (15) (2021)
   PUBMED   33876776
  REMARK    GeneRIF: Inherited deficiency of stress granule ZNFX1 in patients
            with monocytosis and mycobacterial disease.
REFERENCE   6  (bases 1 to 7209)
  AUTHORS   Lango Allen,H., Estrada,K., Lettre,G., Berndt,S.I., Weedon,M.N.,
            Rivadeneira,F., Willer,C.J., Jackson,A.U., Vedantam,S.,
            Raychaudhuri,S., Ferreira,T., Wood,A.R., Weyant,R.J., Segre,A.V.,
            Speliotes,E.K., Wheeler,E., Soranzo,N., Park,J.H., Yang,J.,
            Gudbjartsson,D., Heard-Costa,N.L., Randall,J.C., Qi,L., Vernon
            Smith,A., Magi,R., Pastinen,T., Liang,L., Heid,I.M., Luan,J.,
            Thorleifsson,G., Winkler,T.W., Goddard,M.E., Sin Lo,K., Palmer,C.,
            Workalemahu,T., Aulchenko,Y.S., Johansson,A., Zillikens,M.C.,
            Feitosa,M.F., Esko,T., Johnson,T., Ketkar,S., Kraft,P., Mangino,M.,
            Prokopenko,I., Absher,D., Albrecht,E., Ernst,F., Glazer,N.L.,
            Hayward,C., Hottenga,J.J., Jacobs,K.B., Knowles,J.W., Kutalik,Z.,
            Monda,K.L., Polasek,O., Preuss,M., Rayner,N.W., Robertson,N.R.,
            Steinthorsdottir,V., Tyrer,J.P., Voight,B.F., Wiklund,F., Xu,J.,
            Zhao,J.H., Nyholt,D.R., Pellikka,N., Perola,M., Perry,J.R.,
            Surakka,I., Tammesoo,M.L., Altmaier,E.L., Amin,N., Aspelund,T.,
            Bhangale,T., Boucher,G., Chasman,D.I., Chen,C., Coin,L.,
            Cooper,M.N., Dixon,A.L., Gibson,Q., Grundberg,E., Hao,K., Juhani
            Junttila,M., Kaplan,L.M., Kettunen,J., Konig,I.R., Kwan,T.,
            Lawrence,R.W., Levinson,D.F., Lorentzon,M., McKnight,B.,
            Morris,A.P., Muller,M., Suh Ngwa,J., Purcell,S., Rafelt,S.,
            Salem,R.M., Salvi,E., Sanna,S., Shi,J., Sovio,U., Thompson,J.R.,
            Turchin,M.C., Vandenput,L., Verlaan,D.J., Vitart,V., White,C.C.,
            Ziegler,A., Almgren,P., Balmforth,A.J., Campbell,H., Citterio,L.,
            De Grandi,A., Dominiczak,A., Duan,J., Elliott,P., Elosua,R.,
            Eriksson,J.G., Freimer,N.B., Geus,E.J., Glorioso,N., Haiqing,S.,
            Hartikainen,A.L., Havulinna,A.S., Hicks,A.A., Hui,J., Igl,W.,
            Illig,T., Jula,A., Kajantie,E., Kilpelainen,T.O., Koiranen,M.,
            Kolcic,I., Koskinen,S., Kovacs,P., Laitinen,J., Liu,J., Lokki,M.L.,
            Marusic,A., Maschio,A., Meitinger,T., Mulas,A., Pare,G.,
            Parker,A.N., Peden,J.F., Petersmann,A., Pichler,I.,
            Pietilainen,K.H., Pouta,A., Ridderstrale,M., Rotter,J.I.,
            Sambrook,J.G., Sanders,A.R., Schmidt,C.O., Sinisalo,J., Smit,J.H.,
            Stringham,H.M., Bragi Walters,G., Widen,E., Wild,S.H.,
            Willemsen,G., Zagato,L., Zgaga,L., Zitting,P., Alavere,H.,
            Farrall,M., McArdle,W.L., Nelis,M., Peters,M.J., Ripatti,S., van
            Meurs,J.B., Aben,K.K., Ardlie,K.G., Beckmann,J.S., Beilby,J.P.,
            Bergman,R.N., Bergmann,S., Collins,F.S., Cusi,D., den Heijer,M.,
            Eiriksdottir,G., Gejman,P.V., Hall,A.S., Hamsten,A., Huikuri,H.V.,
            Iribarren,C., Kahonen,M., Kaprio,J., Kathiresan,S., Kiemeney,L.,
            Kocher,T., Launer,L.J., Lehtimaki,T., Melander,O., Mosley,T.H. Jr.,
            Musk,A.W., Nieminen,M.S., O'Donnell,C.J., Ohlsson,C., Oostra,B.,
            Palmer,L.J., Raitakari,O., Ridker,P.M., Rioux,J.D., Rissanen,A.,
            Rivolta,C., Schunkert,H., Shuldiner,A.R., Siscovick,D.S.,
            Stumvoll,M., Tonjes,A., Tuomilehto,J., van Ommen,G.J., Viikari,J.,
            Heath,A.C., Martin,N.G., Montgomery,G.W., Province,M.A., Kayser,M.,
            Arnold,A.M., Atwood,L.D., Boerwinkle,E., Chanock,S.J., Deloukas,P.,
            Gieger,C., Gronberg,H., Hall,P., Hattersley,A.T., Hengstenberg,C.,
            Hoffman,W., Lathrop,G.M., Salomaa,V., Schreiber,S., Uda,M.,
            Waterworth,D., Wright,A.F., Assimes,T.L., Barroso,I., Hofman,A.,
            Mohlke,K.L., Boomsma,D.I., Caulfield,M.J., Cupples,L.A.,
            Erdmann,J., Fox,C.S., Gudnason,V., Gyllensten,U., Harris,T.B.,
            Hayes,R.B., Jarvelin,M.R., Mooser,V., Munroe,P.B., Ouwehand,W.H.,
            Penninx,B.W., Pramstaller,P.P., Quertermous,T., Rudan,I.,
            Samani,N.J., Spector,T.D., Volzke,H., Watkins,H., Wilson,J.F.,
            Groop,L.C., Haritunians,T., Hu,F.B., Kaplan,R.C., Metspalu,A.,
            North,K.E., Schlessinger,D., Wareham,N.J., Hunter,D.J.,
            O'Connell,J.R., Strachan,D.P., Wichmann,H.E., Borecki,I.B., van
            Duijn,C.M., Schadt,E.E., Thorsteinsdottir,U., Peltonen,L.,
            Uitterlinden,A.G., Visscher,P.M., Chatterjee,N., Loos,R.J.,
            Boehnke,M., McCarthy,M.I., Ingelsson,E., Lindgren,C.M.,
            Abecasis,G.R., Stefansson,K., Frayling,T.M. and Hirschhorn,J.N.
  TITLE     Hundreds of variants clustered in genomic loci and biological
            pathways affect human height
  JOURNAL   Nature 467 (7317), 832-838 (2010)
   PUBMED   20881960
REFERENCE   7  (bases 1 to 7209)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   8  (bases 1 to 7209)
  AUTHORS   Dunphy,E.J. and McNeel,D.G.
  TITLE     Antigen-specific IgG elicited in subjects with prostate cancer
            treated with flt3 ligand
  JOURNAL   J Immunother 28 (3), 268-275 (2005)
   PUBMED   15838384
  REMARK    GeneRIF: MAD-CaP-5 (KIAA1404) is a novel prostate cancer antigen.
REFERENCE   9  (bases 1 to 7209)
  AUTHORS   Nakayama,M., Kikuno,R. and Ohara,O.
  TITLE     Protein-protein interactions between large proteins: two-hybrid
            screening using a functionally classified library composed of long
            cDNAs
  JOURNAL   Genome Res 12 (11), 1773-1784 (2002)
   PUBMED   12421765
REFERENCE   10 (bases 1 to 7209)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK096594.1, AB037825.2, DA809204.1, AU140771.1 and AL049766.14.
            
            On Nov 22, 2018 this sequence version replaced NM_021035.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB037825.2, SRR14038194.859988.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000396105.6/ ENSP00000379412.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AK096594.1         370-389
            21-1749             AB037825.2         1-1729
            1750-2299           DA809204.1         5-554
            2300-2856           AB037825.2         2280-2836
            2857-3328           AU140771.1         96-567
            3329-3397           AB037825.2         3309-3377
            3398-7209           AL049766.14        23150-26961         c
FEATURES             Location/Qualifiers
     source          1..7209
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q13.13"
     gene            1..7209
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /note="zinc finger NFX1-type containing 1"
                     /db_xref="GeneID:57169"
                     /db_xref="HGNC:HGNC:29271"
                     /db_xref="MIM:618931"
     exon            1..37
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            38..146
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..5842
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /codon_start=1
                     /product="NFX1-type zinc finger-containing protein 1"
                     /protein_id="NP_066363.1"
                     /db_xref="CCDS:CCDS13417.1"
                     /db_xref="GeneID:57169"
                     /db_xref="HGNC:HGNC:29271"
                     /db_xref="MIM:618931"
                     /translation="MEERRPHLDARPRNSHTNHRGPVDGELPPRARNQANNPPANALR
                     GGASHPGRHPRANNHPAAYWQREERFRAMGRNPHQGRRNQEGHASDEARDQRHDQEND
                     TRWRNGNQDCRNRRPPWSNDNFQQWRTPHQKPTEQPQQAKKLGYKFLESLLQKDPSEV
                     VITLATSLGLKELLSHSSMKSNFLELICQVLRKACSSKMDRQSVLHVLGILKNSKFLK
                     VCLPAYVVGMITEPIPDIRNQYPEHISNIISLLQDLVSVFPASSVQETSMLVSLLPTS
                     LNALRASGVDIEEETEKNLEKVQTIIEHLQEKRREGTLRVDTYTLVQPEAEDHVESYR
                     TMPIYPTYNEVHLDERPFLRPNIISGKYDSTAIYLDTHFRLLREDFVRPLREGILELL
                     QSFEDQGLRKRKFDDIRIYFDTRIITPMCSSSGIVYKVQFDTKPLKFVRWQNSKRLLY
                     GSLVCMSKDNFETFLFATVSNREQEDLCRGIVQLCFNEQSQQLLAEVQPSDSFLMVET
                     TAYFEAYRHVLEGLQEVQEEDVPFQRNIVECNSHVKEPRYLLMGGRYDFTPLIENPSA
                     TGEFLRNVEGLRHPRINVLDPGQWPSKEALKLDDSQMEALQFALTRELAIIQGPPGTG
                     KTYVGLKIVQALLTNESVWQISLQKFPILVVCYTNHALDQFLEGIYNCQKTSIVRVGG
                     RSNSEILKQFTLRELRNKREFRRNLPMHLRRAYMSIMTQMKESEQELHEGAKTLECTM
                     RGVLREQYLQKYISPQHWESLMNGPVQDSEWICFQHWKHSMMLEWLGLGVGSFTQSVS
                     PAGPENTAQAEGDEEEEGEEESSLIEIAEEADLIQADRVIEEEEVVRPQRRKKEESGA
                     DQELAKMLLAMRLDHCGTGTAAGQEQATGEWQTQRNQKKKMKKRVKDELRKLNTMTAA
                     EANEIEDVWQLDLSSRWQLYRLWLQLYQADTRRKILSYERQYRTSAERMAELRLQEDL
                     HILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLSKACQHLILI
                     GDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMCPEIARLLTPHIY
                     QDLENHPSVLKYEKIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCKYFLC
                     QEYLPSQITILTTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQ
                     EGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQIGPMLRL
                     CCQNHPETHTLVSKASDFQKVPEGGCSLPCEFRLGCGHVCTRACHPYDSSHKEFQCMK
                     PCQKVICQEGHRCPLVCFQECQPCQVKVPKTIPRCGHEQMVPCSVPESDFCCQEPCSK
                     SLRCGHRCSHPCGEDCVQLCSEMVTIKLKCGHSQPVKCGHVEGLLYGGLLVKCTTKCG
                     TILDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCIGECPPCQRTCQNRC
                     VHSQCKKKCGELCSPCVEPCVWRCQHYQCTKLCSEPCNRPPCYVPCTKLLVCGHPCIG
                     LCGEPCPKKCRICHMDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRYMNEQKDD
                     EVAIRLKVCPICQVPIRKNLRYGTSIKQRLEEIEIIKEKIQGSAGEIATSQERLKALL
                     ERKSLLHQLLPEDFLMLKEKLAQKNLSVKDLGLVENYISFYDHLASLWDSLKKMHVLE
                     EKRVRTRLEQVHEWLAKKRLSFTSQELSDLRSEIQRLTYLVNLLTRYKIAEKKVKDSI
                     AVEVYSVQNILEKTCKFTQEDEQLVQEKMEALKATLPCSGLGISEEERVQIVSAIGYP
                     RGHWFKCRNGHIYVIGDCGGAMERGTCPDCKEVIGGTNHTLERSNQLASEMDGAQHAA
                     WSDTANNLMNFEEIQGMM"
     exon            147..1955
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            1956..2087
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            2088..2236
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            2237..2386
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            2387..2501
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            2502..2749
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..2889
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            2890..3044
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3190
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            3191..3301
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            3302..3397
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     exon            3398..7209
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7187..7192
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /note="hexamer: ATTAAA"
     polyA_site      7209
                     /gene="ZNFX1"
                     /gene_synonym="IMD91"
                     /note="major polyA site"
ORIGIN      
        1 actcgccggc ggcagtgaaa ggacgcgccg gagccggttt tccagataac agaaagtaac
       61 gtgaaggaat tcaggtgact cagacatgga ggagagaaga cctcatctgg atgccaggcc
      121 caggaattcc cataccaacc acagaggccc tgtggatgga gagttaccac caagagctag
      181 aaatcaggcc aataacccac cagccaatgc tctccgagga ggagccagcc accctggaag
      241 gcatcctagg gccaacaacc atcctgctgc ttactggcag agggaagaga gatttagggc
      301 catgggcagg aacccacatc aaggaaggag gaaccaggag gggcatgcca gcgacgaagc
      361 tagagaccaa agacatgacc aggagaatga caccaggtgg agaaatggca accaggactg
      421 taggaaccgc agaccaccat ggtccaatga caacttccag cagtggcgga ctccccacca
      481 gaagcctaca gaacagccac agcaggcgaa gaaactgggc tacaagttct tagaaagtct
      541 tctgcagaaa gacccttctg aggtggtcat cacacttgcc acaagtttag ggctgaaaga
      601 gctcctttct cattcttcca tgaaatctaa cttccttgag ctcatctgtc aggttcttcg
      661 gaaggcttgt agctccaaaa tggatcgcca gagtgttctc catgtactgg gcatattgaa
      721 aaactccaaa tttctcaaag tctgcctgcc tgcttatgtg gtagggatga tcactgaacc
      781 catccctgac atccgaaacc agtatccaga gcacataagc aacatcatct ccctcctcca
      841 ggaccttgta agtgtcttcc ctgccagctc tgtgcaggaa acttccatgc tggtttccct
      901 cctgccaacc tctcttaatg ctctgagagc ctctggtgtt gacatagaag aggaaacgga
      961 gaagaacctg gaaaaggtac agactatcat tgaacatctg caggaaaaga ggcgagaggg
     1021 cactttgaga gtggatacct acactctagt gcagcctgag gcagaagacc atgttgagag
     1081 ctaccgaacc atgcccattt accctaccta caatgaagtg cacttggatg agaggccctt
     1141 ccttcgcccc aatatcattt ctggaaaata cgacagcact gctatctatc tggataccca
     1201 cttccggctc ctgcgagaag atttcgtcag acctttacgg gaaggtattt tggaacttct
     1261 ccaaagcttt gaagaccagg gcctgaggaa gagaaagttt gatgacatcc gaatctactt
     1321 tgacaccagg attatcaccc ccatgtgttc atcatcaggc atagtctaca aggtgcagtt
     1381 tgacacaaaa ccactgaagt ttgttcgctg gcagaattcc aaacgattgc tctatgggtc
     1441 tttggtatgc atgtccaagg acaacttcga gacatttctt tttgccaccg tatctaacag
     1501 ggagcaggaa gatctctgcc gaggaattgt ccagctctgc ttcaatgagc aaagccaaca
     1561 gctgctagca gaggtccagc cctctgactc tttcctcatg gtagagacaa ctgcatactt
     1621 tgaggcctac aggcacgtcc tggaaggact ccaggaggtc caggaggaag atgttccctt
     1681 ccagaggaat atcgtggagt gtaactctca tgtgaaggag ccaaggtact tgctaatggg
     1741 gggcagatac gactttaccc ccttaataga gaatccttca gccactgggg aatttctaag
     1801 aaatgtcgag ggtttgagac atcccagaat taatgtctta gatcctggcc agtggccctc
     1861 aaaagaagcc ctgaagctgg atgactccca gatggaagcc ttgcagtttg ctctcacaag
     1921 ggaactggct attattcaag gacctcctgg aacaggcaaa acctatgtgg gtctaaaaat
     1981 tgttcaggcc ctcctaacca acgagtctgt ttggcaaatt agcctccaga agttccccat
     2041 cttggttgtg tgttatacta atcatgcttt ggaccagttt ctggaaggca tctacaattg
     2101 tcagaagacc agcattgtgc gggtgggtgg aaggagcaac agtgaaatcc tgaagcagtt
     2161 caccctaagg gagctgagga acaagcggga attccgccgc aacctcccca tgcacctccg
     2221 aagggcctac atgagtatca tgacacagat gaaggagtca gagcaagagc ttcatgaagg
     2281 agccaagacc ctggagtgca ccatgcgtgg tgtcctacgg gaacagtacc tgcagaagta
     2341 catctcaccc cagcactggg aaagtctcat gaatggacca gtgcaggata gtgaatggat
     2401 ttgcttccag cactggaagc attccatgat gctggagtgg ctaggtcttg gtgtcggttc
     2461 tttcacgcaa agtgtttctc cagcaggacc tgagaataca gcccaggcag aaggggatga
     2521 ggaggaagaa ggggaggagg agagttcgct gatagagatc gcagaggaag ctgacctgat
     2581 tcaagcagac cgggtgattg aggaggaaga ggtggtgagg ccccagcggc ggaagaagga
     2641 agagagtgga gcagaccagg agttggctaa aatgcttctg gccatgaggc tagaccattg
     2701 tggcactggg acagcagctg gacaggagca agccacagga gagtggcaga cccagcgcaa
     2761 ccagaaaaag aaaatgaaaa aaagagtgaa ggatgagctt cgcaaactga acaccatgac
     2821 tgcagccgag gccaacgaga tcgaggatgt ttggcagctg gacctcagtt ctcgctggca
     2881 gctttatagg ctctggctac agttgtacca ggctgacacc cgccggaaga tcctcagcta
     2941 tgaacgccag taccgcacat cagcagaaag aatggccgag ctgagactcc aggaagacct
     3001 gcacattctt aaagatgccc aggttgtagg aatgacaacc acaggtgctg ccaaataccg
     3061 ccagatccta cagaaggtgg agccgaggat tgtcatagtg gaagaagctg cggaagtcct
     3121 tgaggcccat accattgcca cattgagcaa agcttgccag cacctcattt tgattgggga
     3181 ccaccagcag ctgcgcccca gtgccaacgt gtatgatctg gccaagaact tcaaccttga
     3241 ggtgtccctt tttgaacggc tagtgaaagt aaacattccc tttgtccgtc tgaattacca
     3301 gcaccgtatg tgccctgaaa ttgcccgcct tttgaccccc cacatttacc aggatctgga
     3361 gaatcatcca tctgttctta agtatgagaa gattaagggg gtgtcttcca accttttctt
     3421 tgtagaacac aactttcctg aacaggaaat ccaagagggc aaaagccatc agaaccagca
     3481 tgaggctcac tttgtggtag agctgtgcaa gtacttcctg tgccaggaat acctgccttc
     3541 ccagatcacc atcctcacta cctataccgg gcagctcttc tgcctgcgca aactgatgcc
     3601 tgccaagaca tttgctggcg tcagggtcca tgttgtggac aaataccaag gggaagagaa
     3661 tgacatcatc ctcctctcgc tagtgcggag caaccaagaa ggcaaggtgg gttttctgca
     3721 gatatccaac cgcatctgtg tggccttgtc ccgagccaag aagggaatgt actgcatcgg
     3781 aaacatgcag atgctggcca aggtgcccct gtggagcaag atcattcata cacttcgaga
     3841 gaacaatcaa ataggcccca tgctccggct ctgctgccag aaccaccctg aaacccacac
     3901 cttagtatcc aaagcttctg acttccaaaa agtacccgaa ggaggctgca gcctgccctg
     3961 cgagttccgc ctgggctgtg ggcatgtctg cacccgtgcc tgccaccctt atgactcttc
     4021 acacaaggag ttccaatgca tgaagccatg ccagaaggtc atctgtcagg aagggcaccg
     4081 gtgtcccctt gtttgcttcc aggagtgtca gccttgtcag gtgaaggtgc ccaaaaccat
     4141 tcctcggtgc ggccatgaac aaatggtccc ttgttccgtg cctgagtcag atttctgctg
     4201 ccaggagcct tgctccaagt ctctgagatg tgggcacaga tgcagccacc catgtggtga
     4261 ggactgtgtg cagctgtgtt cagaaatggt caccataaaa ctcaagtgtg ggcacagtca
     4321 accggtaaaa tgtggtcatg tggaaggcct cctgtatggt ggtctgctag tcaagtgtac
     4381 cacaaagtgt ggcactatct tggactgcgg gcatccttgc ccaggctcct gccacagctg
     4441 cttcgaaggg cgtttccatg aacgctgtca gcagccctgc aagcgcctgc ttatctgctc
     4501 acacaagtgc caggaaccat gcattggtga gtgcccaccc tgccagcgga cctgtcagaa
     4561 ccgctgtgtc cacagccagt gcaagaagaa atgtggggag ctgtgtagtc cctgcgtgga
     4621 accctgtgtc tggcgctgcc agcactacca gtgcaccaaa ctctgctctg agccctgcaa
     4681 ccgaccccca tgctatgtgc cttgtactaa gctgctagtt tgtggccacc cctgcattgg
     4741 tctctgtggg gagccatgcc ccaagaaatg ccggatctgc cacatggatg aggtcaccca
     4801 aatattcttt ggctttgagg atgagcctga tgcccgcttt gtgcagctgg aagactgcag
     4861 ccacatcttt gaggtgcaag ccctagaccg ctacatgaat gaacagaagg atgatgaagt
     4921 cgccatcaga ttgaaagtct gccctatctg ccaggtgccc atccgcaaaa acctgaggta
     4981 tggaactagc ataaaacagc ggctagaaga gattgaaatc atcaaggaaa agatccaggg
     5041 ctcagcaggg gaaatagcaa ccagccagga acggcttaag gccctgctgg agaggaagag
     5101 cctcctccac cagctgcttc ctgaagactt cctgatgtta aaggagaagc tggcccagaa
     5161 aaatctgtca gtgaaggacc tgggtctggt tgagaattac atcagcttct atgaccacct
     5221 ggccagcctg tgggattccc tgaaaaagat gcatgtctta gaagagaaaa gagtgaggac
     5281 tcgactagaa caggtccatg agtggctggc caagaagcgc ttgagcttca ctagccagga
     5341 actaagtgac ctccgaagtg aaatccagag gctcacatac ctggtgaacc ttctgacccg
     5401 ctacaagata gcagagaaga aggtgaaaga tagcatagca gtagaggtct atagtgtcca
     5461 gaatatcctt gagaaaacat gtaagttcac ccaagaggat gaacaacttg tgcaggaaaa
     5521 gatggaagct ctgaaagcca cccttccctg ctctggcctg ggcatctcag aggaagagcg
     5581 agtgcagatt gtcagtgcca taggttatcc tcgtggtcac tggttcaagt gccgcaatgg
     5641 ccatatctat gtgattggcg attgtggggg agccatggag aggggcacgt gtcctgactg
     5701 taaggaagtg attggtggca caaatcatac tctggaaaga agcaaccagc ttgcttctga
     5761 aatggatgga gcccagcatg ctgcctggtc tgacacggcc aacaacctga tgaactttga
     5821 ggagatccag gggatgatgt aggaagatgg tacaccactg ccttttgccc tcgccactga
     5881 atgactgggg ccagctccct aatgaaggaa ctgaagtttg ttttttatta tcatcctttt
     5941 taggctgggc gcagtggctt acgcctgtaa tcccagcact ttgggaggcc gaggcaggcg
     6001 gatcacgagg tcaggagttc gagaccagcc tgaccaacat ggcgaaaccc cgtctctact
     6061 aaaaatacaa aaattagctg ggcgttatgg cgggcgcctg taatcccagc tacttgggag
     6121 gctgaggcag aagaatcgct taaacccagg aggcggaggt tgcagtgagc tgagatcatg
     6181 ccattgcact ccagtctggg cgacaggagc aagactctgt ctcaaaaaaa aaaaaatcat
     6241 tctttttagt cttagcacct acttaaggat ccacttttag ggctcaccca catttgtttc
     6301 tagatttacc cctgcgctag agtaagcact ttatctccag aactgagagc aaagttaaca
     6361 aatctcaccc cttctctcct gcaaattagt ggacagactc cctggaacat gtttggggct
     6421 tccacctagg gccacctagt ggtatctctg ggtctttact tggtcagatg tttattctac
     6481 attgttcccc aggaacagag tatgagctca ttgatgcaga ccgattctaa ttgccaggcc
     6541 ctaatttgca gactaactct cataataaac agaggcccat agttgtttat gaactgctta
     6601 tcccttaaag gagcacaaga acccctccct gccctccttg ggcaccctgc ctccaggaga
     6661 tggaggcacg tgataagaca aaagactgca ccaactcacc ctgacacagt tacatagtca
     6721 ctgagagtgg ggaagatggg acagcccaca tgctgcataa gatgggcctt atgcagcagg
     6781 cccaggtcgt cattaaggag tgaccccttt cctgtaacct gcactttggg atggtagaag
     6841 tttctttacc tgctgacagg tttggtggca ctgctggtta cccctgggcc ctgaatggag
     6901 ctaaaatcac atttggtacc agcagcacct atcccaagtg tgatccttca tcccaacact
     6961 ccctcttgga gctgttccct gggtagagct agcatgccag cagcttctgc aggctccaaa
     7021 cccaggccag aagccagacc caggcctgct gcctgcatct gcattccctc cttccagtgt
     7081 tccttagaac agacatttag gtatctcagg tcctttctaa gtgtcccttt cctatgtatg
     7141 catttccttt ttttgtcttt actatgcact ttagcttata aagccaatta aaaacaatga
     7201 ttgagaaaa
//
