LOCUS       NM_001080409            7861 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 99 (ZNF99), mRNA.
ACCESSION   NM_001080409 XM_001132267
VERSION     NM_001080409.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7861)
  AUTHORS   Bellefroid,E.J., Marine,J.C., Ried,T., Lecocq,P.J., Riviere,M.,
            Amemiya,C., Poncelet,D.A., Coulie,P.G., de Jong,P., Szpirer,C. et
            al.
  TITLE     Clustered organization of homologous KRAB zinc-finger genes with
            enhanced expression in human T lymphoid cells
  JOURNAL   EMBO J 12 (4), 1363-1374 (1993)
   PUBMED   8467795
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008626.6 and AC024563.6.
            
            On Nov 22, 2018 this sequence version replaced NM_001080409.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA1970526 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000596209.4/ ENSP00000472969.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               AC008626.6         103370-103507       c
            139-265             AC008626.6         88554-88680         c
            266-361             AC008626.6         87661-87756         c
            362-5575            AC008626.6         73825-79038         c
            5576-7861           AC024563.6         156256-158541       c
FEATURES             Location/Qualifiers
     source          1..7861
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     gene            1..7861
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /note="zinc finger protein 99"
                     /db_xref="GeneID:7652"
                     /db_xref="HGNC:HGNC:13175"
                     /db_xref="MIM:603981"
     exon            1..138
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..2730
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /note="zinc finger protein ENSP00000375192"
                     /codon_start=1
                     /product="zinc finger protein 99"
                     /protein_id="NP_001073878.2"
                     /db_xref="CCDS:CCDS59369.1"
                     /db_xref="GeneID:7652"
                     /db_xref="HGNC:HGNC:13175"
                     /db_xref="MIM:603981"
                     /translation="MGSLTFWDVTIEFALEEWQCLDMAQQNLYRNVMLENYRNLVFLG
                     IAVSKLDLITCLKQGKEPWNMKRHEMVTKPPVISSHFTQDFWPDQSIKDSFQEIILRT
                     YARCGHKNLRLRKDCESVNEGKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNS
                     NRYKIRHTKKKTFKCMKCSKSFFMLSHLIQHKRIHTRENIYKCEERGKAFKWFSTLIK
                     HKIIHTEDKPYKYKKCGKAFNISSMFTKCKIIHTGKKPCKCEECGKVFNNSSTLMKHK
                     IIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQII
                     HTGKKPYKCEECGKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHT
                     GQKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKRFSALRKHKIIHTGK
                     QPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHMEEKP
                     CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKPYK
                     CEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCE
                     ECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEEC
                     GKAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGK
                     AFKWSSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAF
                     NNSSTLRKHEIIHTGEKSYKCEECGKAFQWSSKLTLHKVIHMERNPANVKNVAKLLNI
                     SQPLENMR"
     exon            139..265
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /inference="alignment:Splign:2.1.0"
     exon            266..361
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /inference="alignment:Splign:2.1.0"
     exon            362..7861
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      7548
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /note="major polyA site"
     regulatory      7840..7845
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /note="hexamer: AATAAA"
     polyA_site      7861
                     /gene="ZNF99"
                     /gene_synonym="C19orf9; F8281"
                     /note="major polyA site"
ORIGIN      
        1 gccgttgttt ctggttccag ctggagctcc ggatctcgtt tttactgctc tgtgtcctta
       61 gcctctgtgg ccctgtgacc tgtaggtatt tggagatcca cagctaggac gccaggaccc
      121 cctggaagct tagaaatggg atcgttgaca ttttgggatg tgaccataga attcgctctg
      181 gaggagtggc aatgcctgga catggctcag cagaatttat ataggaatgt tatgttagag
      241 aactacagaa acctggtctt cctgggtatc gctgtctcta agctagactt gataacttgt
      301 ctgaagcaag ggaaagagcc ttggaatatg aagagacatg agatggtaac taaaccccca
      361 gttattagtt ctcattttac acaagacttt tggccagatc agagcataaa agattctttc
      421 caagaaataa tattgagaac atatgcaaga tgtggacata agaatttacg attaagaaaa
      481 gattgtgaaa gtgtcaatga gggtaagatg cacgaagaag cttataataa acttaaccaa
      541 tgttggacaa ctacccaggg aaaaatattt cagtgtaaca aatatgtgaa agtctttcat
      601 aaatattcaa attcaaatag atataagatt agacacacta aaaagaaaac tttcaaatgt
      661 atgaaatgta gcaaatcatt tttcatgctt tcacacttaa ttcaacataa gagaattcat
      721 actagagaga atatctacaa atgtgaagaa cgtggcaaag cctttaaatg gttctcaacc
      781 cttattaaac ataagataat tcatactgaa gacaaaccct acaaatataa gaaatgtggc
      841 aaagctttta acatctcttc aatgttcact aaatgtaaga taattcatac tggaaagaaa
      901 ccctgcaaat gtgaagaatg tggcaaagtt tttaacaatt cctcaaccct tatgaaacat
      961 aagataattc atactgggaa gaaaccatat aaatgtgaag aatgtggcaa agcttttaag
     1021 caatcctcac accttactag acataaagca attcatactg gagagaaacc ctacaaatgc
     1081 gaagaatgtg gcaaagcttt taaccatttc tcagccctta gaaaacatca gataattcat
     1141 actggaaaga aaccctacaa atgtgaagaa tgtggcaaag cttttagcca gtcctcaacc
     1201 cttagaaaac atgagataat tcatactgaa gagaaaccct acaaatatga agaatgcggc
     1261 aaagctttta gcaatttgtc agcccttaga aaacatgaga taattcatac tggacagaaa
     1321 ccctacaaat gtgaagaatg tggtaaagct tttaagtggt cctcaaaact tactgtacat
     1381 aaggtaattc atactgcaga gaaaccctgc aaatgtgaag aatgtggcaa agcttttaag
     1441 cgtttctcag cccttagaaa acataagata attcatactg gaaagcaacc ctacaaatgt
     1501 gaagaatgca gcaaagcttt tagcaatttt tcagccctta gaaaacatga gataattcat
     1561 actggagaga aaccctacaa atgtgaagaa tgtggtaaag cttttaagtg gtcctcaaaa
     1621 cttactgtac ataaggtaat tcatatggaa gagaaacctt gcaaatgtga agaatgtggc
     1681 aaagctttta agcatttctc agcccttaga aaacataaga taattcatac tggaaagaaa
     1741 ccctacaaat gtgaagaatg tggcaaagct tttaacaatt cctcaaccct tatgaaacat
     1801 aagataattc atactgggaa gaaaccatac aaatgtgaag aatgtggcaa agcttttaag
     1861 caatcttcac atcttactag acataaagca attcatactg gggagaaacc ctacaaatgt
     1921 gaagaatgtg gcaaagcttt taaccacttc tcagccctta gaaaacatca gataattcat
     1981 actggaaaga aaccctacaa atgtgaagaa tgtggcaaag cttttagcca gtcctcaacc
     2041 cttagaaaac atgagataat tcatactgga gagaaaccct acaaatgtga agaatgtggt
     2101 aaagctttta agtggtcctc acaccttact agacataaag taattcatac tgaagagaaa
     2161 ccctacaaat gtgaagaatg tggcaaggct tttaaccatt tctcagccct taggaaacat
     2221 aagataattc atactggaaa gaaaccctac aaatgtgaag aatgtggcaa agcttttagc
     2281 cagtcctcaa ctcttagaaa acatgagata attcatactg gagagaaacc ctacaaatgt
     2341 gaagaatgtg gtaaagcttt taagtggtcc tcaaaactta ctgtacataa ggtaattcat
     2401 actgcagaga aaccctgcaa atgtgaagaa tgtggcaaag cttttaagca tttctcagcc
     2461 cttagaaaac ataagataat tcatactgga aagaaaccct ataaatgtga agaatgtggc
     2521 aaagctttta acaattcctc aacccttaga aaacatgaga taattcatac tggagagaaa
     2581 tcctacaaat gtgaagaatg tggtaaagct tttcagtggt cctcaaaact tactttacat
     2641 aaggtaattc atatggagag aaaccctgca aatgtgaaga atgtggcaaa gcttttaaac
     2701 atttctcagc ccttagaaaa catgagataa ttcatactgg aaagaaaccc tacaaatgtg
     2761 aagaatgtgg caaagctttt aacaattcct caacccttag gaaacataag ataatttata
     2821 ctgggaagaa accatacaaa tgtgaagaat gtggcaaagc ttttaagcag tcctcacacc
     2881 ttactagaca taaagcagtt catactgggg agaagcccta caaatgtgga gaatgtggaa
     2941 aagcttttaa caattcctca acccttaaga aacataagct aattcatact agggagaaat
     3001 cgtacaaatg tgaagaatgt ggcaaagctt ttagcaattt ctcagccctt aggaaacata
     3061 agataattca tactggggag aaaccataca aatgtgaaga atgtggtaaa gcttttaagt
     3121 ggtctcaaaa cttatggaac ataaggtaat tcatactgta gagaaaccct acaaatgtga
     3181 agaatgtggc aaagctttta agcatttctc agcccttaga aaacatgaga taattatact
     3241 ggaaagaaac cctacaaatg tgaagaatgt ggcaaagctt ttaacaattc ctcaaccctt
     3301 atgaaacata agataattca tactggggag aaaccgtaca aatgtgaaga atgtggcaaa
     3361 ggttttaaca atttctcgac ccttatgaaa cataagataa ttcatactgg ggagaaaccg
     3421 tacaaatgtg aagaatgtgg caaagctttt aagcaatcct cacaccttac taaacataaa
     3481 tcaattcata ctggagagaa accctacaaa tgtgaagaac gtggcaaagc ttttagccat
     3541 ttctcacgcc ttactaaaca taggataatt catactggaa agaaacccta caaatgtgaa
     3601 gagtgtggta aagcatttag tcctcaaacc ttactaaaca taagataatt cattctggag
     3661 agaaacccta caaatgtgaa gaatgtggca aagcctttaa ccagtcctca caccttactc
     3721 aacataaaac aattcatact ggagggaaaa cctacaaatg tgaagaatgt ggcaaagctt
     3781 ttaaccatct ttcagccctt actaaacata agataattca tactggggag aagccctaaa
     3841 aatgtgaaga atgtgtcaaa gctttcaacc attttacaaa ccttaataca cataagataa
     3901 tttatactag agacagaccc tccatatgtg aagaatgtgg caaagctttt aaccagtcct
     3961 caagccttaa taggcagaaa acaattcatg ctggagagaa accccacaaa tgtaaagaat
     4021 gtggcaaagc ctttaaccag tcctcacacc ttaaatacac ataaaataat tgatactgga
     4081 ggaaaaccct acaaatataa taaaggtgac aaagctttta accattgctc agctgttact
     4141 caaaatgaga gaattcctaa agaagataaa ctccacaaat gtgaataata tggcaaagct
     4201 tttaactggt cctcaaatct tactgaatgt aagataattc atactgaaga taaacccttc
     4261 aaatgtgagg aatgtggcaa agcttttaat cagtcctcaa atcttactga acataagata
     4321 attcatagta gagacaaaca ctgcaaatat gaagaatggg caaagctttt aaccagtcct
     4381 caaactttac tcaacataaa ataatttatc ttggagagga acactacaaa tttaaagaat
     4441 ttggcaaaac ttttaactgc ttctcaaaac ttactgaaca taagataatt catactggag
     4501 agatacttta caaatgtgaa gaatgtggca aagcttctaa cgggttctca gatcttactg
     4561 aatataagat aaattagaga gaaacccgcc tcatgtgaag agtgtggcaa aacttttaac
     4621 tggtcctcaa accttactga acataagata attcatactg aagagaaacc ctacaaatat
     4681 gaaaactgtg gcaaagcttt taactggttt tcagacctta ctcaacagaa aatagttgat
     4741 actgaagaca aactctagaa atgtgaagaa tgtggcaatg cttttaatca gttaaacttt
     4801 attagacata agaaaattcg tactggagaa aaaccctaca aatgtgaaga aagtggcaat
     4861 gcttttagcc agtcctcaac tcttgctaaa caacataatt caatgggaga gaaaccctac
     4921 aaatgtgaat aatgccataa gcattcttca attttttttt tttttttttt gaaacagagt
     4981 ttcgccctag ttgcccaggc tctggagtgc agtggcacaa tctcggctca ctgcaacctc
     5041 cgcctcctgg gttttcaagc gattctcctg cctcagcctc ccgagtagca gggactatag
     5101 gcatgtgcca ccacgcccac ctaattttgt atttttagta gagacggggt ttctccatgt
     5161 tggtcaagct ggtctcgaac tcccgacctc tggtgatctg cccgcctcgg cctcccaaag
     5221 tgctgggatt aaaggcgtga gccaccgtgc ccagcctaat tcttcaattc ttaataaaca
     5281 atttatactg aagagaaacc ctacaaacgt gaagaatgtt gcaaagcttt taacgtcctc
     5341 aaaccttact gaacataaga taattcataa tggaaactag ccctacaaat atgaagaatg
     5401 tggcaaacac tgtaaccatt tctcacatct taccacacat taagataatt catactgaag
     5461 agaaacccga caaatgtgaa gaatgtaaca aagtctttaa ctggtcttca actcatacta
     5521 aatataagag aattcataca gaagataaat tttataaata tgaagaatgt gacaaaagct
     5581 ttaaaaacat ttcaaccctt attacacata agataattta tgttgtagag aaattctaca
     5641 aatgtgaaga atgtggcaaa gttttttttt tttttttgaa atggagtctc actctgtcgc
     5701 ccaaattgga gtgcaatggt gcaatctcag ttcattgcaa cctccgcctc ctgggttcaa
     5761 gcgattctct ggcctcaacc tcccaagcag ctgggattgc aggcgcctgc caccacgccc
     5821 agctaatttt tgtattttta gtagagacgg ggtttcacca ttttgaccag gctggttttg
     5881 aactcctgac ctcaagtgat ccacccgcct tggcctccca aagtgcccca aagtgctggg
     5941 attacaagca tgagccattg agcccggtcg aatgtggcaa agtttttaat aagttatcaa
     6001 atcatactgg agagaagctc tacaaaccta aaagacatga cagtgctctt gagaacacct
     6061 taaacttttc taaacataaa agaaatcata gtgtcaagaa gccctagatg tgagtcatgt
     6121 cacaaagcct ttaaatggtt gtcacacttg agtataagct aatttatcct agagaaaact
     6181 atgaagaatg tggcaaaata tttaaccaat actcacacct tatcgcatag gaaagcattt
     6241 atacttgaaa aaaaatgtac acctatgaag aatgtggaaa agccattaat atctgctcac
     6301 atcttaacat cacagagttt atacttaaaa caaatattaa aaatgcaatt actgtgagaa
     6361 tatcttttag aaaatataaa ccttagaatg gtgaagagta tttcttttga tgacaaacat
     6421 tacaaatata aagacggttg tagtactata tttgtatcac agatcttatt gtgcatattt
     6481 tgtgctagag aaaaacccta aagttgctca aactttgttc aatatcaggg aatgtataat
     6541 agagaaaaaa acctgcaaat gtaataaatt tggaaaaaag tttataaact acagcttaga
     6601 aaacagagta agtttttttt gtagatgcag taaatatgaa aaatattcaa tccaaaatta
     6661 actctgtaaa tgtcagagaa ttcacagtag aaatgataag gcactggcac ttcagactac
     6721 actaaatcag agtgttgagt aaaaaaaata atttcaatct aaaatttaga taagttattt
     6781 gcatataact taaaaaagag gaggtgattt tttggagaat tataattaca tttgaagtat
     6841 actttttgta tacttcaaat atcaaaaaaa ttaacatcac aatattgaaa aaaattacag
     6901 actctgaaaa gcaaataagg atgtaattca actctcaagt tacttcatgc tcttcattcc
     6961 tactttattt acatgtgaaa gcatgcgatc aattgttgct gcatcagaga tatgaaagat
     7021 tcttttttat tagatgggca ttatttatga cctttttcat aaaagagaaa ggatattaaa
     7081 atataaaatg catgataaaa atctaaatgg agaggctttt tgtggttaac ttaaaatatt
     7141 gagtgatgta tgaggtaggt gttctgagga atatattttt gtgcattata gtgagaaaaa
     7201 cattttaaaa ttttagttaa aattaaaatt aaattagtga tgtattatat tagttgtgct
     7261 tttatgtaat gtagtacatt cataaatttt tagattatat gtaaacttaa ttttttaaac
     7321 attttttgac atgttaagtc tgttgtacat tcaatgaagt gttattatgc cactcgcttt
     7381 aacctatccc accttactca agggtgtagg taagagatgg caacagttta ctatttggta
     7441 agagtggaat aacatctcta gtaatctctt tttttcagtg gctttaacct gcaaataaat
     7501 taaagaatat tgttctcgta ggttacattt ttatactttt aatcttattt aaacttcttt
     7561 ttttttttgc cttgacaaat ttaaacttat ttttcttaac ttttatgggt acatagtgtg
     7621 tagatatatt tctgccatat atagcatatt ttgataccag cataaaatat gtaataatca
     7681 cgtcagggta aatgagggat tcttcacctt caacatttat tccttgaatt acaagcaatc
     7741 caaatctaca cttttagtca ctttgaaata taaaactaaa ttgttatctt tattatagcg
     7801 tcatttttgt ggtcataata aaaatcatat aggaatgtaa ataaaatcta tacatatctg
     7861 g
//
