LOCUS       NM_001423470            9156 bp    mRNA    linear   PRI 20-FEB-2024
DEFINITION  Homo sapiens zinc finger protein 852 (ZNF852), transcript variant
            2, mRNA.
ACCESSION   NM_001423470
VERSION     NM_001423470.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9156)
  AUTHORS   Ke,C., Zhou,H., Jiang,B. and Xie,X.
  TITLE     Zinc finger protein 852 is essential for the proliferation, drug
            sensitivity, and self-renewal of gastric cancer cells
  JOURNAL   Cell Biol Int 46 (4), 579-587 (2022)
   PUBMED   34957631
  REMARK    GeneRIF: Zinc finger protein 852 is essential for the
            proliferation, drug sensitivity, and self-renewal of gastric cancer
            cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC099669.2.
            
            Transcript Variant: This variant (2) represents the allele encoded
            by the reference genome (GRCh38) and uses an alternate in-frame
            splice site, compared to variant 1. The encoded isoform (2) is one
            amino acid longer than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074967.1956959.1, BU934706.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AC099669.2         67252-67316         c
            66-157              AC099669.2         59664-59755         c
            158-284             AC099669.2         59241-59367         c
            285-9156            AC099669.2         48465-57336         c
FEATURES             Location/Qualifiers
     source          1..9156
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     gene            1..9156
                     /gene="ZNF852"
                     /note="zinc finger protein 852"
                     /db_xref="GeneID:285346"
                     /db_xref="HGNC:HGNC:27713"
     exon            1..65
                     /gene="ZNF852"
                     /inference="alignment:Splign:2.1.0"
     exon            66..157
                     /gene="ZNF852"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..1777
                     /gene="ZNF852"
                     /note="isoform 2 is encoded by transcript variant 2;
                     putative zinc finger protein 852"
                     /codon_start=1
                     /product="zinc finger protein 852 isoform 2"
                     /protein_id="NP_001410399.1"
                     /db_xref="GeneID:285346"
                     /db_xref="HGNC:HGNC:27713"
                     /translation="MVRPQDTVAYEDLSEDYTQKKWKGLALSQRALHWNMMLENDRSM
                     ASLAGRNMMESSELTPKQEIFKGSESSNSTSGGLFGVVPGGTETGDVCEDTFKELEGQ
                     PSNEEGSRLESDFLEIIDEDKKKSTKDRYEEYKEVEEHPPLSSSPVEHEGVLKGQKSY
                     RCDECGKAFYWSSHLIGHRRIHTGEKPYECNECGKTFRQTSQLIVHLRTHTGEKPYEC
                     SECGKAYRHSSHLIQHQRLHNGEKPYKCNECAKAFNQSSKLFDHQRTHTGEKPYECKE
                     CGAAFSRSKNLVRHQFLHTGKKPYKCNECGRAFCSNRNLIDHQRTHTGEKPYKCNECG
                     KAFSRSKCLIRHQSLHTGEKPYKCSECGKAFNQISQLVEHERIHTGEKPFKCSECGKA
                     FGLSKCLIRHQRLHTSEKPYKCNECGKSFNQNSYLIIHQRIHTGEKPYECNECGKVFS
                     YNSSLMVHQRTHTGEKPYKCNSCGKAFSDSSQLTVHQRVHTGEKNLMNVLSVGKPLVS
                     VPLLITTSELMLERSPQVWLGHLLKAWFSETDSKDL"
     exon            158..284
                     /gene="ZNF852"
                     /inference="alignment:Splign:2.1.0"
     exon            285..9156
                     /gene="ZNF852"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9133..9138
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF852"
                     /note="hexamer: AATAAA"
     polyA_site      9156
                     /gene="ZNF852"
                     /note="major polyA site"
ORIGIN      
        1 ggtaggcgcg gggcggtcgg ctgcggtggc ggcgtttgga tgattgtctc tcggcggcgg
       61 agtcgctcaa tgtacttctc cagttcctac ccttcctcaa gtggggaact caggagacca
      121 agcaggggca actgtacttc ggatggtcag gccccaggat actgtggcgt atgaggacct
      181 gtctgaggac tatactcaga agaaatggaa aggtctcgca ctcagtcaga gagccctgca
      241 ctggaacatg atgctggaaa atgaccgtag catggcttct ttggcaggta ggaacatgat
      301 ggagagttca gagctgactc cgaagcagga aatttttaaa ggatcagagt catctaatag
      361 cacatcaggg ggactctttg gggtggttcc tgggggaaca gagactggag atgtttgtga
      421 agataccttc aaagagttag aaggacaacc ctcaaatgaa gaagggagca gactagaaag
      481 tgatttcttg gaaataatag atgaggataa gaaaaaatcc acaaaagaca gatatgagga
      541 atataaggaa gttgaggaac atccacctct gtcttccagt cctgttgaac atgaaggagt
      601 tttaaaggga cagaaatcct atcgatgtga tgaatgtggc aaagcttttt attggagttc
      661 gcacctcatt ggtcatcgga gaatccacac tggagagaaa ccctatgagt gtaatgagtg
      721 tgggaagacc ttcaggcaaa cctcccagct cattgttcat ctcagaaccc acacagggga
      781 aaagccctat gaatgcagtg agtgtggaaa ggcctatagg cacagctccc atctcattca
      841 acaccagaga ctccataatg gggagaaacc ctataaatgt aatgaatgtg caaaagcttt
      901 taatcagagc tccaaactct tcgaccacca gagaacccat actggggaga aaccttatga
      961 atgtaaggag tgtggggcgg cctttagtcg gagtaaaaat cttgttcgac atcagtttct
     1021 gcacactggt aagaaacctt ataagtgtaa tgaatgtggg agagcattct gttccaatag
     1081 aaatctcatt gaccatcaga gaacccacac tggggagaag ccttataaat gtaatgaatg
     1141 tggcaaagcc ttcagtcgga gtaaatgtct tattcgacat cagagcctcc acactgggga
     1201 aaagccatac aaatgtagtg aatgtgggaa agccttcaat cagatctctc aacttgttga
     1261 acatgagcga attcatactg gagaaaaacc atttaagtgt agtgagtgtg gtaaggcatt
     1321 cggtctgagt aaatgtctta ttcggcacca gaggcttcac acaagtgaaa agccctataa
     1381 atgcaatgag tgtggaaaat ccttcaatca aaactcatac ctcattatac accagagaat
     1441 tcacactggt gagaaaccct atgaatgtaa tgagtgtggg aaggtcttca gttataattc
     1501 tagtcttatg gtacatcaga gaacccatac tggggaaaaa ccctataaat gcaatagttg
     1561 tgggaaagcc tttagtgaca gctcacagct tactgtgcac cagagagtcc acactggaga
     1621 gaaaaacctt atgaatgtat tgagtgtggg aaagccttta gtcagcgttc cacttttaat
     1681 caccaccagc gaactcatgc tggagagaag ccctcaggtc tggctcggtc atcttcttaa
     1741 ggcatggttt tctgagacag acagcaaaga cctttgagtt aagctgtctt tataagaagg
     1801 atgttcatca tggtctcctt ggagaccact aatcacagtg gagaccatac ctacttgctt
     1861 ttccttgggt cactaaggtg ggagagtagg tgcaacttag tctgatcctt acttagtagg
     1921 aaattgggga ttacatctgt cattaacttg taggttccct tctttctctt aaaaaactat
     1981 ttaaaactct atcttgttag tatgcattcc ataatcagat tctgcatttc tcaagaacag
     2041 cagttatatt acctttattc tattgcagtt cctccactga accatttacg tgaagtcact
     2101 ttttaagtca ttctgcaaga ttattcttcc ctgctccttg gctatctcct tccacagcta
     2161 ctttaaaaat ttgtactgta agctacatcc tctcatcatt tttgtgtttt ctagctagaa
     2221 aactttttct tcctgtttgc taatcacttc cttcacaatg ttcaagattt atgccatttc
     2281 tgaaagactt tcttcttcaa atagtttttc gtttctttta tacctctatt gatttggcct
     2341 taatgcttta aattagctgg tgctacgatg tgtaactgtt aaatgttttt gtaaattgtt
     2401 cttaacttac aaggtgatat gtgtatcaca tatgtacaaa gtatacacat atatagttgt
     2461 gtatgtgtat actttctttt tttttttttt tttttttgag acagagtctc agtctccctc
     2521 ttgttgccca ggctagagtg caatggtgca atcttggctc accacaacct ctgcttctcg
     2581 ggttcaagcg attctcctgc ctcagcctcc cgagtagctg ggattacagg catgtgccac
     2641 catgcctggc taattttttt ttttgtattt ttagtagaga tggggtttct ctatgttggt
     2701 caggctggtc ttgaactccc aatctcaggt gatccgcccg cctcagcctc ccaaagtgct
     2761 gggattacag gtgtgagcca ctgcacccag cctcaaatgt gtatactttc ataccagctt
     2821 gtaagcttct gagatcaggt atggtatcta tttctttata tgcataatag tttgaatatg
     2881 ctagttctta agttttaaaa ttcaaattga gccatcataa acgtgggcac aggctcccgt
     2941 ctccctccca ttacactgga ctagaagctt ctaaagaagg aagtggcatc gtaatatatc
     3001 acatataaag gctcactgat atcttctact tgtagccctg gaagtcttac tactggtact
     3061 tcagccttga agagctaatg gatttgtgtg tgaatgagtg tctgtttatc taggtattgg
     3121 gttgggcagt catatcctac tgataacatg ctttgagctg cacacttact ccatttctga
     3181 actatttgac tgcatcctgc ttcctaaata aaagttatag tcggccaggc tcagtggctc
     3241 acgcctgtaa tcccagcact ttgggaggcc gaggtgggca gatcacttga tgtcaggagt
     3301 tcgagaccag cctggccaac atggtgaaac cccatctcta ctaaaataca aaaattagcc
     3361 gagtatggtg gtgtgcacct gtaatcccag ctacttggga ggctgaggca ggagaattgc
     3421 ttgcacctgg gcagaggttg taatgagctg agattgtgcc actgcacccc agcctgggtg
     3481 acagagtgag actacatctc aaaaacaaca aacaaaaaaa accttacagt caaaatttac
     3541 tgcaagaaga cttgactttc atggctgtaa tatagatgat tgaaaatttc agctagcagc
     3601 attcctggat gattggaatt cagagtgatg aggtttttgg taaaatagta gtatcaaact
     3661 aatctgtttt ccttatcagc tagtcctttc tcactacaac tgctgtctta atttcaagat
     3721 gagaactgtg ccttaattat cttccagacc acctttcctt ctgcagtcat atgtcagtcc
     3781 atgagcttga accacctttc cttccaccct tgcaataatg gcccagtgcc ggtggacctt
     3841 ttactctaat gttcaccctg ttctctttcc atccccagac tttttttttt tttttttgag
     3901 acggagtctt gctctgtcgc ccaggctgga gtgcagtggt acgatctcag ctcactgcaa
     3961 gctctgcctc ccaggttcat gccattctcc tgcctcagcc tcccgagtag ctgggagtac
     4021 aggcgcccgc caccaggccc ggctaatttt ttttgtattt ttagtagaga tggggtttca
     4081 ccgtgttagc caggatggtc tcgatctcct gacctcgtga tctgcctgcc tcggcctccc
     4141 aaagtgctgg gattacaggc atgagccacc acgcctggcc tccatccccc agatttctta
     4201 acaggctgac aggatccgca gtatgacaaa ggtggaggag gaggctagag gggcaatgtc
     4261 agtcatgtaa cctggagggg tgattttgtg cactgtggtg tatgtttcag acaatgcagg
     4321 agaaaggaaa gagagttgag gatcaagaaa attagaatta aatgtgattg ttggggagat
     4381 gtctcagaca aagttagaaa ggattactgg gggcctaaag tttttcaggg ccttttgaaa
     4441 tttctaaact tgtctgggca cagtggctca tgcctgtaat cccagcactt tgggaggctg
     4501 aggcggtcag atcacctgag tccaggagtt tgagaccagc ctggccaaca ttgtaaaacc
     4561 ccgtttctac taaaaataca aaaattagct gggtgtggtg gtgcacgcct gtaatcccag
     4621 ctattcagga gtctgaggca agagaatcac ttgaacctgg agggcagaga ttgcagtgag
     4681 ccaagatcac accactgtac tgcagcctgg gcaacagagc gagactctgt ctcaataaca
     4741 acaacaaaac aacaaaccgg agctcatgac acggctggaa ttttaccatt tgtgaatatg
     4801 tattttaaat gttttcagct tgtttttttg tatttttttc cattttcttt taaaagatat
     4861 gcagatagga ctttttcctc tttaactgtc ttattttggg agcccccaga tttcagggaa
     4921 gagccccaca ctatatgagc acatgagttg gacatttctg gttccccgcc ctgagttgga
     4981 cattgccagt catgtctgca gaagaaccat cctgcctgtt ggaagctgca gttttacctt
     5041 ctggttcttg cctgctcatc ccctaccata ctaagcctcc agagtgtggg aatgtgcacc
     5101 atttcctaac tatattaact cactgccacc agtctggtgt gggtgctcag tacaagtgaa
     5161 tcctgaaaaa gcctcaggct cttggatgga ggaaaactgg ctgcatttga aagccatact
     5221 tcaatttcta ttggtcactg ctagtataaa ctttaattat tgatttaaac aaattttatc
     5281 tggatccaat tatgttgata aattattttt aggtttaata atttgttaga ttcatttcct
     5341 agcttttcta ggtttagaat aaataatgat ttatttgtct tttgatgtca cttatgttgt
     5401 gcattagcaa gaacttcaga aaacatggaa cagtagatgt ctttctctta acgcttgggg
     5461 gaatgttttt agtattctgc agtttcatat cgtgttcatt gttggattct gatgttctgt
     5521 tagatttagg aagtttcctt ctaatcttat ttctagaaga agcagtgtag tttagtggtt
     5581 aagagcacag attttgttcc cagtgcccta ggttcaaatc ctgagtccac cactttgtta
     5641 ggtgtgtgat cctgggcaaa tcacttacct tccttgtatc ttattcctcc atctataaaa
     5701 tggagctacc tcatagggtt gtgaagaata cattattgta acaatactgg gcacacagtg
     5761 cacagtttcc caattattat tatacttaca gttttgtttt ctgttttttt ttttgacaag
     5821 gtctccctct gttgctcagg ctggagtgta gtgatgtgac cataggtcac ctcagccttg
     5881 aactcctggg ctcaagagat gctcctgcct caacctcccc tatagttagg aatacaggca
     5941 tgtgccacca tgcccgacta agtttttatt tttatttttt gtaaacatgg ggtttcacta
     6001 ttttgctcag gctggtcttg cggtcctggc ctcaagcgat catcctgcct cagcttctct
     6061 aagtgctggg aatacaggtg tgagccacca tgcctggcct atacttaaaa agtttttatt
     6121 aggattggtt gctatattat atcaagttta aaaactccat cattgtaatt ttatgagtta
     6181 tggttttttc tttttgtaat tcattttctt gacaagtttg caaatatttg caatttcctt
     6241 gtacttttca agtaaaatct atttgttcat agtgaatttt tattaagtac agaagtagat
     6301 tcaatttggt aatgctttgc tagctttgca aaagaatttg gaaaaaattt tgtttatctt
     6361 attgctatgg agagtttgta taacatggga attgttcctt gaaggcttgc taaaagtaac
     6421 tgggcctggt tctttgggtg aggggattgg gagggatata tctttagcaa ctgttttagt
     6481 cagtttgagc tattataaca aaataccata gaggatggct taaacaacag acatttattt
     6541 ctcacagttc tgtagtcttc ataattcaac atcaagatgc cagaatggtt gagtgctggt
     6601 gagggctctc ttcctggttt gcagatggcc ccctttttcc tgtgtcctca aatttcagag
     6661 agcaagagca ctggtgcctc ttccaagtct tttaagggcg ttagtgagag tgacagcccc
     6721 attctcatga cctactccaa tcctagttat tttccaaagg ccccccaccc ccaaatataa
     6781 catttggggt tagggcttca acataaatat tcattctata acattccact cctagccact
     6841 ctattcatat ccttacatac aaaataagtt cattccatcc taacagcctc caaagtttta
     6901 actcattcta gtatcaacta acatttaaag tccaaagtct catctaaata tctaaatatc
     6961 taaataaagg ccgggcatgg tggctcacgc ctgtaatccc agcactttgg gaggccgagg
     7021 cgggtggatc actacgtcag gagttcgaga ccagcctgac caacatggtg aaaccccatc
     7081 tctactaaaa atacaaaaat tagctgggcg tgatggtgtg cacctgtaat cccagctaca
     7141 cggggaggct gaggcaggag aatcgcttga acccgagaga cagaggttgc agtgagccga
     7201 gatcgcacca ttgcactcca gcctgggcga cagtgagact ttgtctcaaa aatatctaaa
     7261 tcagatatgg gtgagaccca aggtttagct tatcctgagg caaaattccc ctccagctgt
     7321 gaacctatga aaccagacaa gttatgtgct tccaaaatac agtgatggga taggcaggat
     7381 taggtattcc aattccaaaa gtgagaaatt ggaaggaaga aagggatgat gaggctgggt
     7441 gtgatagctc atgcctttaa tcctagcact ttgggaggct gaggtgggag gattgcttga
     7501 gtccaggagt tcgagaccag cctgggcaac atagggagac cttatttcta caaaaataat
     7561 aaaaataatt agttgggcat ggtggcttga gcatgggagt tcgaggctac agtgagttgt
     7621 gatcgtactg cactccagcc tggatgacag agtgaaaccc tatcaataaa aaataaaaaa
     7681 ggatggggga gcagggggat gatggtccta tgcaagtcta aaacttagca aggcacgttt
     7741 catgagatct taggctcatg aataatcctc tttggtccta tactgtcctc tccaggaccc
     7801 cctgggcggt ggtcctgacc cgatagatct gccaggcagg ggtgactccc ccgtggcttt
     7861 tgttggagac catctggcct gtggaaactg gggcagtatc cctcatgatc tctaaatagc
     7921 caagagaaga gtcattcttg tatggaacaa tggacattca cagccttcct cattcctggc
     7981 tttaggactt cagatacaat catgtcagag ctcagggctt caacatatga attttggggg
     8041 cacagttcag tccatagcaa tacttccatt cccctgacct gcaacatgtc cagttacttc
     8101 gaaaagtact tgtcatccac tatattaata acatgctcat tgccagccta tgaaacaagt
     8161 tgaccactcc atacataagg tcatagataa tatgacacat gcaggttgag ttgtcagccc
     8221 tgataagatc ccaagacttg cccaacaagt gcagtccctg gagctacctg gtccagtaat
     8281 tagaggagta ttcctgataa agtcaaatat tgtccttggc agcccccacc taaaagaagc
     8341 tcaatagctg gtatgcctgt ttgtctattg gagataacat gtatcacatc tgagtattat
     8401 tttgcctcct ttagttaaaa ttacccacaa cacagccacc tctgaatggg gccctcaaca
     8461 acagcagact cgagaggcct actatgcatt aacatgggcc tgacattaat gtaggcccat
     8521 ggaactacag gtctcattga ctcttaccca tacagattgg atactgcggc aacaagagac
     8581 tgctatcagg atgcaccagg cccttaggtt ttggacatat aaattaccca agatggttgc
     8641 catatacatt ccctttgaat ggcagctact agcctgctat tggactctaa tttaaacaga
     8701 acacttgacc actgaagcac tgtatgtgac cttaagacct gagctgccca tctcatgcag
     8761 gtattattaa cgaaaaataa aaatggaagc cccagtttag aaatacccta aggctgacta
     8821 cccgcaaccg tgtaaccaaa actaatcatt ctgattttcc tgaaatgctg tctctgatca
     8881 taaatgaaat gcaaaatgta agctttacat ccttgccagc atgattcact gaaattaaac
     8941 caatcagcta tagaccaaca agcttaaaca gctcaacttg ccctaaaaag aatgtataac
     9001 agccaattat aaaaaaggtc aaaatattcc ccccctttat gcattataaa ctgtgttgta
     9061 actgctgtaa gattaatttc ttaccacttg atttgagtct tctagattgt ggtctgtact
     9121 tcttgtttga acaataaact tttaaatttt tcttta
//
