LOCUS       NM_001193552            7712 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 850 (ZNF850), transcript variant
            1, mRNA.
ACCESSION   NM_001193552
VERSION     NM_001193552.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7712)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 7712)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC052603.1, AC020928.7 and AC074138.5.
            
            On Nov 23, 2018 this sequence version replaced NM_001193552.1.
            
            Transcript Variant: This variant (1) is the longer transcript and
            encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC136266.1, SRR1163658.407666.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267752 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000591344.2/ ENSP00000464976.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-952               BC052603.1         8-959
            953-3069            AC020928.7         7413-9529           c
            3070-7712           AC074138.5         195776-200418       c
FEATURES             Location/Qualifiers
     source          1..7712
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.12"
     gene            1..7712
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /note="zinc finger protein 850"
                     /db_xref="GeneID:342892"
                     /db_xref="HGNC:HGNC:27994"
     exon            1..83
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /inference="alignment:Splign:2.1.0"
     exon            84..164
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..3425
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative zinc finger protein ENSP00000330994"
                     /codon_start=1
                     /product="zinc finger protein 850 isoform 1"
                     /protein_id="NP_001180481.1"
                     /db_xref="CCDS:CCDS59379.1"
                     /db_xref="GeneID:342892"
                     /db_xref="HGNC:HGNC:27994"
                     /translation="MNMEGLVMFQDLSIDFSQEEWECLDAAQKDLYRDVMMENYSSLV
                     SLGLSIPKPDVISLLEQGKEPWMVSRDVLGGWCRDSEFRCKTKDSCLPKEIYEVTSSQ
                     WVRMEKCHSLVGSSVRDDWECKGQFQHQDINQERYLEKAIMTYETTPTFCLQTSLTLH
                     HRIHPGEKLYKSTECMAFKYGSELTQQQETHTGEKLYKCKECGKAFHHFSYLVKHQRI
                     HTGEKPCACKEYGKAFISGSHLIQHQKMYTDERPHECQESVKAFRPSAHLIQHWRIHT
                     GDKPYECKECGKSFTSGSTLNQHQQIHTGEKPYHCKQCGKSFTVGSTLIRHQQIHTGE
                     KPYDCKECGKSFASGSALIRHQRIHTGEKPYDCKECGKSFTFHSALIRHQRIHTGEKP
                     YDCKECGKSFTFRSGLIGHQAIHTGEKPYDCKECGKSFTAGSTLIQHQRIHTGEKPYD
                     CKECGKSFASGSALLQHQRIHTGEKPYCCKECGKSFTFRSTRNRHQRIHTGEKPYNCK
                     ECGKSFASGSALLQHQRIHTGEKPYHCKECGKSFTFRSGLIGHQAVHTGEKPYDCKEC
                     GKSFTSRSALIQHQRIHTGEKPYHCKECGKSFTVGSTLLQHQQIHTGEKPYDCKECGK
                     AFRLRLRLTQHQQIHTGEKPYQCQECGKAFVSVSGLTQHHRIHTGEKPYECPDCGKAF
                     RQRTYLNQHRRIHTGEKPYECKECGKSFTFCSGLIQHQQNHTDEKPYDGKECGKSFTS
                     HSTLIQHQQIHTGEKPYDCKECGKSFTSHSTLIQHQQIHTGEKLYDCKECGKSFTSHS
                     TLIQHQPLHTGEKPYHCKECGKSFTLRSALIQHRPVHTGEKRYSCKECGKSFTSRSTL
                     IEHQRIHTGEKPYHCKECGKSFAFRSAIIQHRRIHTGEKPYDCKECGKAFRRRSKLTQ
                     HQRIHTGEKPYRCHECGKAFVRFSGLTKHHSIHTGEKPYECKTCGKSFRQRTHLTLHQ
                     RIHTGDRPYECKECGKSFTCGSELIRHQRTHTGEKPYDCKECGKAFRCPSQLSQHKRI
                     HTGEKTYQCPECGKAFFYASGLSRHQSVHTGEKPYECKTCGKAFKQLTQLTRHQRIHD
                     LT"
     exon            165..291
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /inference="alignment:Splign:2.1.0"
     exon            292..387
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /inference="alignment:Splign:2.1.0"
     exon            388..7712
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5834..5839
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /note="hexamer: AATAAA"
     polyA_site      5858
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /note="major polyA site"
     regulatory      7687..7692
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /note="hexamer: AATAAA"
     polyA_site      7712
                     /gene="ZNF850"
                     /gene_synonym="ZNF850P"
                     /note="major polyA site"
ORIGIN      
        1 gtgccgattt agctgccgcc gcgccttgga gtcctgagga acttggctag gctggccccg
       61 agcggaacca gagaatgctg aggctctaac catggaatat tcggaatgtc ccattctatg
      121 aaggaggttt gctggctgca acaggaatat tcatgaacat ggaggggttg gtcatgttcc
      181 aggatctgtc tatagacttc tctcaggagg aatgggagtg cctggacgct gctcagaagg
      241 acttatacag agatgtaatg atggagaact acagcagcct ggtctcacta ggtctctcta
      301 tcccaaagcc tgatgtgatt tccttactgg agcaagggaa agagccctgg atggtttcaa
      361 gggacgtgct gggaggatgg tgccgagact cggagtttag atgtaagacc aaagattcat
      421 gtttgccaaa agaaatctat gaagtaacat catctcagtg ggtgagaatg gaaaaatgtc
      481 atagccttgt gggctccagt gtcagagatg actgggaatg caaaggccag tttcagcacc
      541 aagatataaa tcaggagcga tatttggaaa aagcaataat gacttatgaa acaacaccaa
      601 ctttctgcct acagacatct ctcactctgc atcatcggat tcatcctgga gagaaactgt
      661 ataaatccac agaatgtatg gcttttaagt atggctcaga acttacacaa cagcaagaaa
      721 cccatactgg tgaaaaactc tataaatgta aggagtgtgg gaaggccttt catcactttt
      781 cctatcttgt taaacatcag agaattcata ctggggaaaa gccctgtgca tgtaaagaat
      841 atggaaaagc ttttatttct ggctcacatc ttattcaaca ccagaaaatg tatacagatg
      901 agagacctca tgagtgtcag gaatccgtga aggcctttag accgtctgca catcttattc
      961 aacattggag aattcatact ggtgacaaac cttatgaatg taaagaatgt gggaaatctt
     1021 ttacttctgg ctcaacacta aatcaacatc agcaaattca cactggtgag aaaccctatc
     1081 attgtaagca atgtggaaaa tcttttactg ttggctcaac actaattcga caccagcaaa
     1141 ttcacactgg tgagaaaccg tatgattgta aggaatgtgg aaaatctttt gcttcaggct
     1201 cagcactaat tcgacatcag cgaattcaca ctggtgagaa accctatgac tgtaaggaat
     1261 gtggaaaatc ttttactttt cactcagctc taattcgaca tcagcgaatt cacactggtg
     1321 agaaacccta tgattgtaag gaatgtggga aatcttttac ttttcgctca gggttaattg
     1381 gacaccaggc aattcacact ggtgagaaac cctatgattg taaagaatgt ggaaaatctt
     1441 ttactgctgg ctcaacacta attcaacatc agcgaattca cactggtgag aaaccctatg
     1501 attgtaagga gtgtgggaaa tcttttgctt cgggctcagc actacttcaa catcagcgga
     1561 ttcacactgg tgagaaaccc tattgttgta aggaatgtgg aaaatctttt acttttcgct
     1621 caacacgcaa tcgacaccag cgaatccaca ctggtgagaa accctataat tgtaaagaat
     1681 gtggaaaatc ttttgcttct ggctcagcac tacttcaaca tcagcgaatt cacactggtg
     1741 agaaacccta tcattgtaag gaatgtggaa aatcttttac ttttcgctca gggctaattg
     1801 gacatcaggc agttcacact ggtgagaaac cctatgattg taaagaatgt ggaaaatctt
     1861 ttacttctcg ctcagcacta attcaacatc agcgaattca cactggtgag aaaccctatc
     1921 actgtaagga atgtggaaaa tcttttactg ttggctcaac actacttcaa catcagcaaa
     1981 ttcacactgg tgagaaacct tatgattgta aggaatgtgg gaaggccttt agacttcgtt
     2041 tacgacttac tcaacatcaa caaatccata ctggtgagaa accttatcaa tgtcaggaat
     2101 gtgggaaagc ctttgtcagt gtctcaggac tcacccaaca tcacagaatt cacactggtg
     2161 agaaacccta tgaatgtccg gactgtggga aggcctttag acagcgtaca taccttaatc
     2221 aacatcggag aattcatact ggtgagaaac cttatgaatg taaagaatgt gggaaatctt
     2281 ttactttctg ctcaggacta attcaacatc agcaaaatca cactgatgag aaaccctatg
     2341 atggtaagga atgtgggaaa tcttttactt ctcactcaac actaattcaa catcagcaaa
     2401 ttcacactgg tgagaaaccc tatgattgta aggaatgtgg gaaatctttt acttctcact
     2461 caacactaat tcaacatcag caaatacaca ctggtgagaa gctctatgat tgtaaggaat
     2521 gtgggaaatc ttttacttct cattcaacac taattcaaca tcagccactt cacactggtg
     2581 agaaacctta tcattgcaag gaatgtggga aatcttttac tcttcgctca gcactaattc
     2641 aacatcggcc agttcacact ggtgagaaac gctacagttg taaagaatgt gggaaatctt
     2701 ttacttctcg ctcaacacta attgaacatc agcgaattca cactggtgag aaaccctatc
     2761 attgtaagga atgtggaaaa tcttttgctt ttcgctcagc aataatccaa catcggcgaa
     2821 ttcacactgg tgagaaaccc tatgattgta aggaatgtgg caaggccttt agacgtcgtt
     2881 caaaacttac tcaacatcaa cgaatccata ctggtgagaa accttatcga tgtcatgaat
     2941 gtggaaaagc ctttgtccgt ttctcaggac tcaccaaaca tcacagtatt cacactggcg
     3001 agaaacccta tgaatgtaag acatgtggga agtccttcag acagcgtaca caccttactc
     3061 tacatcagag aattcatacc ggtgacagac cttatgaatg taaagaatgt gggaaatctt
     3121 ttacttgcgg ctcagaacta attcgacatc agcgaactca cactggtgag aaaccttatg
     3181 attgtaagga atgtgggaag gcctttagat gtccttcaca acttagtcaa cataaacgaa
     3241 tccatactgg tgagaaaact tatcaatgtc cggaatgtgg gaaagccttt ttctatgcct
     3301 caggactcag ccgacatcag agtgttcaca ctggcgagaa accctatgaa tgtaagacat
     3361 gtgggaaggc ctttaaacag cttacacagc ttactcgaca tcagagaatt catgacctaa
     3421 cataattaat gtaggaaact gttctcatgc catttgtcat ggatcatcag cagattccat
     3481 atgtgggtca aatacaatgg atgtgtatta cttcatattc actttttcca gaattacgac
     3541 tttttttttt ttttttgaga cggagtcttg ctctgtcgcc caggctggag tgcagtggcg
     3601 ctatctcggc tcactgcaag ctctgcctcc tgggttcatg ccattctcct gcctcagcct
     3661 ccctagtagc tgggactaca ggtacctgcc accacgcctg gctaattttt ttgtttttgt
     3721 atttttagta gagacagggt ttcactgtgt tagccaggat ggtctcgatc tcctgacctg
     3781 gtgatccacc caccaaaatt aggacattta atactgaaag aaattgataa tgaatgtaga
     3841 tgagttttct atcatgattc aaagcttatt gaagttatac aaattcatat tagagaatgt
     3901 ggtcaatgac aaaagacaac catttactac ctacgtgaca ttaggctagt tatgtaaatt
     3961 ctctgtgcca aaattactaa ttgataaaat gttgatggca atagttgttt ttgtgtattt
     4021 tttgtttgtt tgttttgttt tgagacagag tcttgctctg ttgcccaggc tggagtgcag
     4081 tggtgctatc ttggctcact gcaacctctg cctcctgggt tcaagtgatt ctcctgcctc
     4141 tgcctcctga gtagctcaga ttacaggcat gcaccaccat gcttggctaa tttttgtatt
     4201 tttagtagag acggggtttc actgtgttgg tcagggtggt ctcaaacttt tgacctcgtg
     4261 atccccctac ctcggcctcc caaagtgctg ggattacagg tgtgagccac cacgcctggc
     4321 tagtaatagt ttttttataa taaataagtg tgactatatt tttcatgttt gactactgac
     4381 tttgttttaa gcttcgcctt ccctgtctat ttccctgtct actttagccc ataactgcaa
     4441 aggtggctaa gaaagtcctt gctggaaaga aagcaagcaa aactaaagtc tgtgcgcacc
     4501 ttctcctttg gatccagtgg gcaatttata ttagaaattc caagccgggc gtggtggctc
     4561 acgcctgtaa tgccagcact ttcggaggct gaggtgggtg gatcacctga ggttaagagt
     4621 tcaagaccag cctggccaac atgttgaaac cccatctcta ctaaaaatac aaaatcagcc
     4681 agacatggtg gcatatgcct gtaatcccag ctattcagga ggcaaggctg gagaatcgct
     4741 tgaacctggg aggcggatgt tgcagtgagc cagtcagtgg agcagtcaga acacacacag
     4801 tgtttatcaa ttaagtttgt agtcagaaca cacaccatgt ttatcaatta agtttgctgt
     4861 cttatatgga cacagtttgt gatgccctaa aacaagtagt ggtgcctaag ataatcatag
     4921 gccaccataa cagatataac aacaatgaga aagttgaaat attgttggga tcatccaaat
     4981 atgacacaga tacaaagtga gcacatgctg gtgaataaat ggagccaata gacttgttca
     5041 ctgcatggtt acgtcagagg cgtgtaaacc agagcaactt cttcttgaat aggagctgtg
     5101 taaagtaaca ctgaaaccta ctggactgca ttcctagaca gataagtcat tctaagtcac
     5161 aagatgagat atgaggtcag cataagatac aggtcataaa gaccttgctg agaaaacatc
     5221 ttgcagtaaa gaagtcggcc aaatccaaga tggtgacaag agtgacctct ggtcgtcctc
     5281 actgctatac tcccagcagc accatgacac ccagctaagt ttttattttt tatttcagta
     5341 gagttggagt cttgctttgt tacccaggct ggtcttgaat tcctgtcttc aagcaatctt
     5401 cccaccttat gaatataaag aatggcccac cttgtcctct caaagtgctg ggattacaat
     5461 catgagccac tgcacctggg actttctttt tcttttttct tttttttttt tttgagatgg
     5521 agttttgctc ttgttgccca ggctggagtg caatggcacg atcttggctc actgcaacct
     5581 ccgcctccca ggttcaagcg attctcttga ctcagcctcc tgagtaactg ggattacagg
     5641 catgctccac catgcccgac taatttttgt attatttagt agagacgggg tttctccatg
     5701 ttggtcaggc tggtctctga actctgggca ggactaattt agataaggta gtcaggaaag
     5761 gcatttctta caaggtggta tttgcatgaa tgtagacata tggttgcatt ttattatatg
     5821 taaattacac ttcaataaag ttgatgaaaa aaatcttacc tcatcgtcta tgcacttcgg
     5881 attgttgtat ttcattctat ttaaattaca cttgcgttta aaaaatttaa cacttctcta
     5941 aaacatatct gttgatttgt acttttacta atatgcttat ggatgattta tatacacaca
     6001 cacacacaca catatctttt aagaaggtta ttttaaggtt aatcaattga ggctttgtct
     6061 caattgattt tttttgagac agtctcgttc tgtcgcccag gctggagtgc agtggcgtga
     6121 tctcgactca ctgcaagctc cacctcccag gttcacgcca ttctcctgcc tcagcctccc
     6181 tagtagctgt gactacaggt gcccgccacc acgcctggct aattttttgt atttgtagta
     6241 gagacggaat ttcaccatgt tagccaggat ggtctcaatc tcctgacctc atgacccgcc
     6301 cacctcggcc tcccaaagtg ctgggattac aggcgtgagc caccccgccc ggctcaattg
     6361 attcttttgt ctcaatttgt agtcagttga ggtttgtctc aatttatgga aacaaatcaa
     6421 atgtttgttc tcaaattctt actctgtcat ttattattct ccatgttttt gtaactgctt
     6481 ccttggagat atttaaacat aaatatatac agagagggtg aagatggagg agtgcttttt
     6541 acagttcaca gttgtctttt tcatgtgtga caggtttttg ctgtgttgcc caggctggag
     6601 tgcaatgcca caatcttggc tcactgcagc ctcaacttcc cgggctcaat cgatccccca
     6661 cctcagcctc ccgagtagca aggactacag gcgcacacca ccacacctag ctaatttttg
     6721 tatcttttgt agagacaggg tttcaccatg ttgtccaggc tggtcttgaa ctcttgggct
     6781 caattggtcc tagcacctca gcctcctagg tgctgggatt acaggtgtga gccactgtgt
     6841 tcagccaata ctcttaacgt ttttactttt cacttttaaa aattaactct ttttatgaaa
     6901 aaagtagaat tttttaaaga gcagagaaaa gcacaatgaa gacagaaaga tcacctgtat
     6961 attcttattg accaaagatg atctatttgg ggtaaatcct tttttttttt tttgagacgg
     7021 gagttttgct attgttgccc aggctggagt gcaatggcac gatctcggct taccgcaacc
     7081 tctgcctccc aggtttaaac aattctcctg cctcagcctc ctgagtagct gggattacag
     7141 gcatgcacca ccacgcccgg ctaattttgt atttttaata gagacagggt ttctccatgt
     7201 tgaggctggg cttgaactcc agacctcagg tgatctgact gcctcggcct cccaaagtgc
     7261 tgggattaca ggcaggatcc acgtgcccgg ccggtaaatc cttttaatag aggagtttca
     7321 atatttctcc tctgccatag tattagaaag aaaagaatca ttattgacat ctttacgaca
     7381 ttgagttttt ctcttgtacc tggtgtgtct ttatttcagt aggtattctt ttatgtgctt
     7441 tagtaagtct ttatattttt agcataaaag tgtacacatt tcttgtttta cttatttcta
     7501 gatacttaat ggcttttgtt tataatatga ttgggatatt ttttctgttg tgtaattgat
     7561 tactattact atgtactaaa ctgttggttt ttgtctaagg attgtaacat tgatgaacta
     7621 ctttagtaga tgaaatggtt tcttcatgag attgaattgt ctaaagagat gttggtatta
     7681 tttgtaaata aaagtatttg cctattcctt tc
//
