LOCUS       NM_138374               6348 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens zinc finger protein 845 (ZNF845), transcript variant
            1, mRNA.
ACCESSION   NM_138374 XM_001725105 XM_001725106 XM_001725855 XM_001725857
            XM_039908
VERSION     NM_138374.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6348)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 6348)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
REFERENCE   3  (bases 1 to 6348)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC400704.1 and AC010467.9.
            
            On May 17, 2019 this sequence version replaced NM_138374.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.112763.1,
                                           SRR1803616.266243.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000458035.3/ ENSP00000388311.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               DC400704.1         2-153
            153-220             AC010467.9         106798-106865
            221-526             DC400704.1         223-528
            527-6348            AC010467.9         112357-118178
FEATURES             Location/Qualifiers
     source          1..6348
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..6348
                     /gene="ZNF845"
                     /note="zinc finger protein 845"
                     /db_xref="GeneID:91664"
                     /db_xref="HGNC:HGNC:25112"
     exon            1..44
                     /gene="ZNF845"
                     /inference="alignment:Splign:2.1.0"
     exon            45..132
                     /gene="ZNF845"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..3030
                     /gene="ZNF845"
                     /codon_start=1
                     /product="zinc finger protein 845"
                     /protein_id="NP_612383.1"
                     /db_xref="CCDS:CCDS46170.1"
                     /db_xref="GeneID:91664"
                     /db_xref="HGNC:HGNC:25112"
                     /translation="MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNL
                     VSLDISSKCMMKEFSSTAQGNTEVIHTGTLQRHERHHIGDFCFQEMEKDIHDFEFQWK
                     EDERNSHEAPMTEIKQLTGSTNRHDQRHAGNKPIKDQLGSSFHSHLPELHMFQTEGKI
                     GNQVEKSINSASLVSTSQRISCRPKTHISKNYGNNFLNSSLLTQKQEVHMREKSFQCN
                     ESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDC
                     GKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKCNECGK
                     TFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRTF
                     SRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSF
                     KSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKS
                     NLERHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSAL
                     IYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYLAV
                     HWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHR
                     RLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRL
                     HTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHT
                     GEKPYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGE
                     KPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKP
                     YKCNECGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGKKH"
     exon            133..259
                     /gene="ZNF845"
                     /inference="alignment:Splign:2.1.0"
     exon            260..6348
                     /gene="ZNF845"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3969..3974
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF845"
                     /note="hexamer: AATAAA"
     polyA_site      3998
                     /gene="ZNF845"
                     /note="major polyA site"
     regulatory      4263..4268
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF845"
                     /note="hexamer: AATACA"
     regulatory      4290..4295
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF845"
                     /note="hexamer: AGTAAA"
     polyA_site      4296
                     /gene="ZNF845"
     polyA_site      4316
                     /gene="ZNF845"
     regulatory      5554..5559
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF845"
                     /note="hexamer: AATAAA"
     regulatory      5564..5569
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF845"
                     /note="hexamer: TATAAA"
     polyA_site      5576
                     /gene="ZNF845"
     polyA_site      5583
                     /gene="ZNF845"
     regulatory      6020..6025
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF845"
                     /note="hexamer: AATAAA"
     polyA_site      6042
                     /gene="ZNF845"
ORIGIN      
        1 aaacccggaa gcggatcgca tggagtgatg gtcccaccgc agcggattga cttctaaaga
       61 ctcttggtac gtgaggaaga aacccggaag aggaagagga aagcaaagga gtcagggatg
      121 gctctttctc agggtctatt gacattcagg gatgtggcca tagaattctc tcaggaagag
      181 tggaagtgcc tggaccctgc tcagaggact ctatacaggg acgtgatgct ggagaattat
      241 aggaacctgg tctccctgga tatctcttcc aaatgcatga tgaaggagtt ctcatcaaca
      301 gcacaaggca atacagaagt gatccacaca gggacattgc aaagacatga acgtcatcac
      361 attggagatt tttgcttcca ggaaatggag aaagatattc atgattttga gtttcagtgg
      421 aaagaagatg aaagaaatag ccatgaagca cccatgacag aaatcaaaca gttgacgggt
      481 agtacaaacc gacatgatca aaggcatgct ggaaacaagc ctattaaaga tcagcttgga
      541 tcaagctttc attcgcatct gcctgaactc cacatgtttc agaccgaagg gaaaattggt
      601 aatcaagttg agaagtctat caacagtgct tcgttggttt caacatccca aagaatttct
      661 tgtaggccta aaacccacat ttctaagaac tatgggaata atttcctgaa ttcttcatta
      721 ctcacacaaa agcaggaagt acacatgaga gaaaaatctt tccaatgtaa tgagagtggc
      781 aaagccttta attatagctc agtcttaagg aaacatcaga taatccattt aggagcgaaa
      841 caatataaat gtgatgtgtg tggcaaggtc tttaatcaaa agcgatatct tgcatgtcat
      901 cgtagatgtc acactggcaa gaaaccttac aagtgtaatg attgtggcaa gaccttcagt
      961 caggagttaa cccttacatg ccatcataga cttcatactg gagagaaaca ttacaagtgc
     1021 agtgagtgtg gcaagacctt cagtcgaaat tcagcccttg taattcataa ggcaattcat
     1081 actggagaga aatcttacaa gtgtaatgaa tgtggcaaga ccttcagtca aacgtcatac
     1141 cttgtgtacc atcgtagact tcatactgga gagaaacctt acaaatgtga agaatgtgac
     1201 aaagctttca gtttcaaatc aaaccttgaa agacatagga aaattcatac tggagagaaa
     1261 ccttacaagt gtaatgaatg cagcaggacc tttagtcgga agtcatccct tacacgccat
     1321 cgtagacttc atactggaga gaaaccttat aagtgtaatg attgtggcaa gaccttcagt
     1381 cagatgtcat cccttgtata ccatcgtaga cttcatactg gagagaaacc ttacaaatgt
     1441 gaagaatgtg atgaagcttt cagtttcaaa tcgaaccttg aaagacatag gagaattcat
     1501 actggagaga aaccttacaa gtgtaatgat tgtggcaaga ccttcagtca gacatcatcc
     1561 cttgtatacc atcgtagact tcatactgga gagaaacctt acaaatgtga agaatgtgat
     1621 gaagctttca gtttcaaatc aaaccttgaa agacatagga taattcatac tggagagaaa
     1681 ctttacaagt gtaatgaatg tggcaagacc tttagtcgga agtcatccct tacacgccat
     1741 tgtagacttc atactggaga gaaaccttac cagtgtaatg agtgtggcaa agcctttcgt
     1801 gggcagtcag cacttattta ccatcaagca atccatggta tagggaaact ttacaaatgt
     1861 aatgattgtc accaagtctt tagtaatgct acaaccattg caaatcattg gagaatccat
     1921 aatgaagaga gatcgtacaa gtgtaataga tgtggcaaat ttttcagaca tcgttcatac
     1981 cttgcagttc attggcgaac tcatagtgga gagaaacctt acaaatgtga agaatgtgat
     2041 gaagctttca gtttcaaatc aaaccttcaa agacatagga gaattcatac tggagagaaa
     2101 ccttacaggt gtaatgaatg tggcaagacc tttagtcgga agtcatacct tacatgccat
     2161 cgtagacttc atactggaga gaaaccttac aagtgtaatg agtgtggcaa gaccttcggt
     2221 cgaaattcag cccttataat tcacaaggca attcatactg gagagaaacc ttacaagtgt
     2281 aatgagtgtg gcaaggcctt cagtcagaag tcatccctta catgccatct tagacttcat
     2341 actggagaga aaccttacaa atgtgaagaa tgtgacaaag ttttcagtcg caaatcaagc
     2401 cttgaaaaac acaggagaat tcatactgga gagaaaccat acaaatgtaa ggtttgtgac
     2461 aaagcttttg ggcgtgattc acacctggca caacatacta gaattcacac tggagagaaa
     2521 ccttacaagt gtaatgaatg tggcaagaac ttccgtcaca attcagccct tgtaattcat
     2581 aaggcaattc atagtggaga gaaaccttac aagtgtaatg agtgtggcaa gaccttccgt
     2641 cacaattcag cccttgaaat tcataaggca attcatactg gagaaaaacc ttacaagtgt
     2701 agtgaatgtg gcaaggtttt taatagaaaa gcaaaccttt cacgtcatca tagacttcat
     2761 actggagaga aaccttacaa gtgtaataaa tgtggtaagg tttttaatca acaagcacac
     2821 cttgcatgtc atcatagaat tcatactgga gagaaacctt acaagtgtaa tgagtgtggc
     2881 aaaaccttcc gtcacaattc agtccttgta attcataaga caattcatac tggagagaaa
     2941 ccttacaagt gtaatgaatg tggcaaggtt tttaatcgaa aagcaaaact tgcacgtcat
     3001 catagaattc atactggaaa gaaacattag aaatatgaag aatgtgacaa agtttacagt
     3061 tgtaaatcaa gtcttgaaag acaggagaat tcatactgga gagaaagctt acaaatgtaa
     3121 gagtttgtga caagaatctt gggcgtgatt cacacctggc ccaacaaact agaagtcaca
     3181 ctggagagaa accttacaag tgtactgagt gtggcaaagc ctttagtggg cagtcaacac
     3241 ttattcacca tcaggcaatc catggtatag ggaaacttta ctaatgtaat gattatcaca
     3301 aagtcttcag taacactaca accgtttcaa atcattggag aatccataat gagagatttt
     3361 gaaagtgtaa taaatgtggc aaatttttca gacattgttc ataccttgca gttcatcggt
     3421 gaactcatgc tggagagaaa ccttacaaat gtcatgattg tggcaaggtc ttcagtctag
     3481 cttcatctta tgcaaaacag gagacttcat acaggagaca aacttcacaa gtatgatgat
     3541 tgcagcaaag cctttacttc acgttcacac ctaattagac atcagagaat ccatactgga
     3601 cagaaatctt acaaatgtca tcagtgtggc aaggtcttca gtctgagatc accccttaag
     3661 gaacatcaga aaattcattt ttgagatgat tgttccaaat gcaatgagta tagcaaacca
     3721 tcaagcatta attggcatta gagtcaattc agcattgact tgagtttgaa ttgacttaac
     3781 attgagttca agcattaatt gacattaaag tgtttatgtt aagaagattg ggccaggcgg
     3841 ggtggctcac gcctgtaatc ccagcacttt gggaggccaa gaccaataga tcacttgagg
     3901 tcaggagttt gagaccagac tggccaacag acatgagtca cttttcccac cctgtatttt
     3961 gtttctttaa taaaaactgt tacgggtttt tatgggtatc tgttgaatct aaatcacatt
     4021 tgtttgtata atcattcaac aatattaaga cttccaatcc atcaatatgg gttgtatgtc
     4081 tatttagttt ttttgatcaa tgtagatttc aaggtacaag cttctcacct ccttaattca
     4141 gtttatttgt aagtattaag tttcatagca aattgaagtg tgttcataag tttctttaaa
     4201 cattatttat tgttaatgta aggaaattca actaattttg ggtgctgatt ttgtattctg
     4261 caaatacatt gagtgggttt attagtatca gtaaaatctt ggttgattct ttgtgatttt
     4321 ctttcttttt tttttgagac agtctcactc tgttacccag gctcttttct ttttttttga
     4381 gaaggagtct cactcttgtc acttggactg gagtacaatg gcacgatctt ggctcactgc
     4441 agcctctgcc tttcgggttt aagtgattct cctgcctact aactgagatt acaggtgcct
     4501 gccaccatgt ccgtataatt tttttgtatt tttagtagag acggggtttc accatgttga
     4561 ccaggttttt cttgaactcc tgacttcagg tgatccgccc ccatcagcat cccaaagttc
     4621 tgggattaca ggtgtgagcc accgcaccca gccagtgatt ttctatatag aatgtcgtat
     4681 catctacaag gaaataattt ttttttttga gacaatgtct ctctctgtcg ccaggctaga
     4741 gtgccgtgga atgatctttg ctcactgcaa cctctgtctc ccacgtccaa gcaattctgt
     4801 ctcagcctcc tgagtagctg ggactacagg cgcatgtcac cacacctagc taatttattt
     4861 atttttttta ttttagtaaa gacggggttt caccatgttg gcccagatgg tgggccaaca
     4921 tggtgagtac cttgaagaga acttgaaaga atatgttaga tcgcctaacc tcattatccg
     4981 cccacttcgg acttgcaaat tgctgggatt atgggtgtga gccatgagcc cggccccaac
     5041 aaatgtaatt ttacttctgt ctttctgatt tggatgagtt ttatttcttt tgctatttaa
     5101 ttgctctgcc taggacagcc agtatttatt gaatatcagg ggtgagagca ttcttgcatc
     5161 atgtgatatc ctacaggaaa accattccat tttccttcat tggttatttc agctgtggtc
     5221 atttcatgga tgatttttat atttttgagg taaaactcta cctatattgt ttaggatttt
     5281 tacgaagaat gaatattgag ttctgtgaaa tgctttttct ctatctattg agataatgtg
     5341 ttttttatct gtcattctgt gcaagtgtgt atcccattga tttgagtatg ttgaaccatc
     5401 cttgcatccc atgaataggt agcacttgga tgtttacaat ccctttttat atcctcttga
     5461 atacagtttg ctagtataag ggtcttcaag aagttcatgg aaaaatacat attatgaaaa
     5521 atttgtgcat aaatttcaca ctttttgtac caaaataaac cagtataaac ttgttataac
     5581 gtctgaacag gctctagttt gaggcactca gaaggataag acatcagttt gaaaagaacc
     5641 tctatcacag caatacaaat tctgttaaaa caagaagaaa catcaaattt acgatgagac
     5701 cagacgcagt ggctcaggcc tgtaatccca gcggttttag aggcccaggc aggtgggtga
     5761 cgtgagccta gggattcaag accagcctgg gcgacatagg ggacctcttc tctgctaaaa
     5821 gtaaaaaaag tcagccaggt gtggtggtgc actgctgtgg tcccagctac tctgggcact
     5881 gaagtgggag gatcagttga agcagggatt ttgaggctga agtgagccct gatctcacca
     5941 ctgcactcca gcctgggtga cagagctaga ccctgtctca aacaagcaaa taaatgagag
     6001 gcataattcc tcctttgaga ataaaggaaa agatttccct tccttttgtc tcttttctca
     6061 ggacgtttat ttagaaaatt tgtaaatgag gccgggcgtg gtggctcacg cctgtaatcc
     6121 cagcactttg ggaggctaag gtgggcggat cacgaggtca ggagatcgag accatcctgg
     6181 ctaacacggt gaaaccccgt ctctactaaa aatacaaaaa attagctggg cgaggtggca
     6241 ggcacctgta gtcccagcta ctcgggaggt tgaggcagga gaatggcgtg aacccagggg
     6301 ggcggaacct gcagtgagcc gagatcgcac cactgcactc cagcctgg
//
