LOCUS       NM_001136509            1905 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens zinc finger protein 843 (ZNF843), transcript variant
            1, mRNA.
ACCESSION   NM_001136509 XM_290712
VERSION     NM_001136509.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1905)
  AUTHORS   Taipale,M., Tucker,G., Peng,J., Krykbaeva,I., Lin,Z.Y., Larsen,B.,
            Choi,H., Berger,B., Gingras,A.C. and Lindquist,S.
  TITLE     A quantitative chaperone interaction network reveals the
            architecture of cellular protein homeostasis pathways
  JOURNAL   Cell 158 (2), 434-448 (2014)
   PUBMED   25036637
REFERENCE   3  (bases 1 to 1905)
  AUTHORS   Taipale,M., Krykbaeva,I., Koeva,M., Kayatekin,C., Westover,K.D.,
            Karras,G.I. and Lindquist,S.
  TITLE     Quantitative analysis of HSP90-client interactions reveals
            principles of substrate recognition
  JOURNAL   Cell 150 (5), 987-1001 (2012)
   PUBMED   22939624
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK096248.1, AK291063.1, BC036762.1 and AC026471.6.
            
            On Nov 22, 2018 this sequence version replaced NM_001136509.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK291063.1, DA569979.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA2142586
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000315678.10/ ENSP00000322899.5
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AK096248.1         239-242
            5-1339              AK291063.1         1-1335
            1340-1901           BC036762.1         1204-1765
            1902-1905           AC026471.6         105064-105067       c
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..1905
                     /gene="ZNF843"
                     /note="zinc finger protein 843"
                     /db_xref="GeneID:283933"
                     /db_xref="HGNC:HGNC:28710"
     exon            1..154
                     /gene="ZNF843"
                     /inference="alignment:Splign:2.1.0"
     exon            155..1905
                     /gene="ZNF843"
                     /inference="alignment:Splign:2.1.0"
     CDS             490..1536
                     /gene="ZNF843"
                     /codon_start=1
                     /product="zinc finger protein 843"
                     /protein_id="NP_001129981.1"
                     /db_xref="CCDS:CCDS45471.1"
                     /db_xref="GeneID:283933"
                     /db_xref="HGNC:HGNC:28710"
                     /translation="MRSLPFALTVESVSARAPTCCSTGRFTQGRQPCKCKACGRGFTQ
                     SASLLQHWRVHSDWRETLSLSPVRQDLLWPLQPHQAPASPLGRSHSSAGVRQGFSGQL
                     CCWLTKEHTLAEALRLSPVPAGFWGPVEADRPPANSHRRVCPFCCCSCGDSVNEKTSL
                     SQRVLPHPGEKTCRGGSVESVSLAPSSVAPDSTSGLRPCGSPGSFLQHLPPSTLLPRP
                     PFLYPGPPLSLQPLVPSGLPAVPAVPLGGLEVAQVPPATQPAAQQEGAMGPRSCASAG
                     RDSREAVQAPGYPEPARKASQHRAAGPLGEARARLQRQCRAPPPPSNPHWRGALPVFP
                     VWKASSRRSNLARH"
     regulatory      1872..1877
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF843"
                     /note="hexamer: AATAAA"
     regulatory      1878..1883
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF843"
                     /note="hexamer: AATAAA"
     polyA_site      1892
                     /gene="ZNF843"
                     /note="major polyA site"
     polyA_site      1905
                     /gene="ZNF843"
                     /note="major polyA site"
ORIGIN      
        1 gggtcctcgc cacgtcccct tcccggagct acgcgcccgg ctgggttccg atccgccgtg
       61 tctctcgggg gcggctcgcg gggcaggggc gctcccggct cggccgcacg cccaagtgtc
      121 atgcgggagg tacgcgggca cgggacctca ccggagagaa tgatggctct gggatctgaa
      181 atctttcctt ccgcaggaac tggacacggc agtgaggacc agcgtatcca agaggatgga
      241 cttagtgatg gggaacaccc agggacatgc ccgagagcct caagaaacac cttcagatga
      301 cattgcccag cgtcttacat tagagaactc tccagacagc ccccgaggcc tggggccggg
      361 tgctgctccc agactgtgag ctcgtggcca cgggaagcct gagtgcggca gaggccccac
      421 agctgcgcca agtgcggcaa agcctcccgt acagttactc cctgagcggt catctccgaa
      481 gccctgctca tgagaagcct cccctttgcc ctgactgtgg aaagcgtttc agccagagct
      541 cctacctgct gcagcaccgg cagattcacc cagggccgtc agccctgcaa gtgcaaggcc
      601 tgcgggaggg gttttactca gagcgcatcc ctcctccagc actggcgggt ccacagcgac
      661 tggcgagaga ccttgtcgct gtccccagtg cggcaagacc tgctgtggcc gctccaacct
      721 catcaagcac cagcgagtcc actcgggaga agccattcgt ctgcgggagt gcggcaaggg
      781 tttagcggcc agctctgctg ctggctcacc aaggagcaca cactggccga agccctgcgt
      841 ctgtccccag taccagcagg tttttgggga ccggtggaag ctgatcggcc accagcgaat
      901 tcacacagga gagtgtgtcc cttctgctgc tgcagctgcg gtgacagtgt caatgagaag
      961 acctccctct cccagcgcgt ccttccgcac ccaggggaga agacctgcag gggtgggagc
     1021 gtggagagcg tcagcctcgc acccagctca gtcgccccgg acagcacctc tgggctccgg
     1081 ccctgtggga gccccgggtc cttccttcaa catctgcccc catccacact cctgccccga
     1141 cctcccttcc tttatcctgg ccccccactc agtctccagc ctctggttcc atccggcctt
     1201 cccgcagtgc ctgcagtgcc tctgggaggc ctggaagttg cccaggttcc gccagccacc
     1261 cagccggcag ctcagcagga gggggcgatg gggcccagaa gctgtgcgag cgcgggacgg
     1321 gactcgcggg aggcggttca ggccccaggc taccctgagc cagcccggaa ggcctcgcag
     1381 cacagagcgg ccggaccgct cggcgaggcc agggccaggc ttcagcgaca gtgccgagct
     1441 cctccaccgc cctcgaaccc acactggaga ggagccctac cagtgtttcc ggtgtggaag
     1501 gcctccagcc ggaggtccaa cctggcccga cactgaagaa ccagcgtgct gcagccctgg
     1561 gtggaattgt tgcagccgcc ggtggactgt ggatctgaga tgcagtcccc tccctccaca
     1621 cagacccgct caggacggct tttctgtatg gcagatcttt ctcagaagtg ctgggggcta
     1681 ttttgtttgt tttttttccc ctgaattctc gctcctttcc cttatacatt aagggattta
     1741 ggcaggtgcg gctgcgggcg gtgactcaca cctgtaatcc cagcgcttta agagaccgag
     1801 gtgggaggat cgcgtgagcc cgaagaattt gagactagcc tgggcagcct agcgagaccg
     1861 catctctgtg aaataaaaat aaaacgagct ggtgtggtgg cgctg
//
