LOCUS       NM_018335               2992 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens zinc finger protein 839 (ZNF839), transcript variant
            1, mRNA.
ACCESSION   NM_018335
VERSION     NM_018335.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2992)
  AUTHORS   Yang,Y.P., Ting,W.C., Chen,L.M., Lu,T.L. and Bao,B.Y.
  TITLE     Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer
            Survival
  JOURNAL   Int J Med Sci 14 (1), 53-57 (2017)
   PUBMED   28138309
  REMARK    GeneRIF: ZNF839 single nucleotide polymorphism association with
            colorectal cancer patients survival
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2992)
  AUTHORS   Scanlan,M.J., Gordan,J.D., Williamson,B., Stockert,E., Bander,N.H.,
            Jongeneel,V., Gure,A.O., Jager,D., Jager,E., Knuth,A., Chen,Y.T.
            and Old,L.J.
  TITLE     Antigens recognized by autologous antibody in patients with
            renal-cell carcinoma
  JOURNAL   Int J Cancer 83 (4), 456-464 (1999)
   PUBMED   10508479
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL352978.6 and AL137229.4.
            
            On Jul 8, 2020 this sequence version replaced NM_018335.5.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853562.10786.1,
                                           SRR14372080.2734448.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000442396.7/ ENSP00000399863.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-308               AL352978.6         122351-122658
            309-1211            AL352978.6         128590-129492
            1212-1436           AL352978.6         134227-134451
            1437-1529           AL352978.6         137159-137251
            1530-1679           AL352978.6         138294-138443
            1680-1817           AL137229.4         12196-12333
            1818-1947           AL137229.4         12474-12603
            1948-2992           AL137229.4         14703-15747
FEATURES             Location/Qualifiers
     source          1..2992
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.31"
     gene            1..2992
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /note="zinc finger protein 839"
                     /db_xref="GeneID:55778"
                     /db_xref="HGNC:HGNC:20345"
     exon            1..308
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..2804
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /note="isoform 1 is encoded by transcript variant 1; renal
                     carcinoma antigen NY-REN-50"
                     /codon_start=1
                     /product="zinc finger protein 839 isoform 1"
                     /protein_id="NP_060805.3"
                     /db_xref="CCDS:CCDS45164.1"
                     /db_xref="GeneID:55778"
                     /db_xref="HGNC:HGNC:20345"
                     /translation="MADAEPEAGGGSEDGGGGGGPAPPGQSGSVARVAPLGPEQLRQV
                     LEQVTKAQPPPPPPPFVLRDAARRLRDAAQQAALQRGRGTEPPRLPRLLPPQQLEAIC
                     VKVTSGETKGQERPMLLPTTIQPQTARKSQLPRGNSCLVGLHIASPQLLRVQPLVRTE
                     PQSCFLSDLCQPPAQGFVQRPLPALQVVPAKRVPAPKAPDEQGSMLTPLSASDPLAVT
                     SLSSSSAHPFISNLHTRHTEKLKKSLKVKTRSGRVSRPPKYKAKDYKFIKTEDLADGH
                     LSDSDDYSELCVEEDEDQRERHALFDLSSCSLRPKSFKCQTCEKSYIGKGGLARHFKL
                     NPGHGQLDPEMVLSEKASGSTLRGCTEERTLSLTSLGLSMPADPCEGGARSCLVTESA
                     RGGLQNGQSVDVEETLPSEPENGALLRSERYQGPRRRACSETLAESRTAVLQQRRAAQ
                     LPGGPAAAGEQRASPSKARLKEFLQQCDREDLVELALPQLAQVVTVYEFLLMKVEKDH
                     LAKPFFPAIYKEFEELHKMVKKMCQDYLSSSGLCSQETLEINNDKVAESLGITEFLRK
                     KEIHPDNLGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESL
                     AANSRGREKPRPLHALAAGFSPPVNVTVSPRSEESHTTTVSGGNGSVFQAGPQLQALA
                     NLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFPGENALEHSSDQDTWDS
                     LRSPGFCSPLSSGGGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAP
                     PLEKILSVDSVAVDCAYRTVPKPGPQPGPHGSLLTEGCLRSLSGDLNRFPCGMEVHSG
                     QRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGTIVSQEEDIVT
                     VTDAEGRACGWAR"
     exon            309..1211
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1436
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1529
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1679
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1817
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1947
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2992
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2970..2975
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /note="hexamer: TATAAA"
     polyA_site      2992
                     /gene="ZNF839"
                     /gene_synonym="C14orf131"
                     /note="major polyA site"
ORIGIN      
        1 gagtccccgc ctcggccgcc atggcggatg cggagccgga ggctgggggc ggcagcgagg
       61 atggcggcgg cggcggcggc ccggctcctc cgggccagag cggcagcgtc gcacgtgtgg
      121 ccccgctggg ccccgagcag ctgcggcagg tcctggagca ggtgacgaag gcgcagccgc
      181 cgccgccgcc gccccccttc gtgctgcggg acgcggcgcg gcggctgcgg gacgcggccc
      241 aacaggccgc cctgcagcgg ggccggggca ccgagccccc gcgcctgccg cgcctgctcc
      301 cgccccagca actagaagcc atttgtgtca aggtaacgtc tggagaaaca aaaggtcagg
      361 aaaggccaat gctcctaccg accacaatcc agccccaaac tgcaagaaag agccagctgc
      421 cccgggggaa ttcctgcctg gtggggctcc atatcgccag ccctcagctg ctcagggtac
      481 agccgcttgt gagaaccgag ccacagtcct gcttcctaag tgacttatgc caacctcctg
      541 ctcaggggtt tgtacagaga ccactgccag ccctccaggt ggtccctgca aagagagtcc
      601 cagcccccaa ggctccagat gaacagggct ccatgttgac ccctttgtct gcctctgacc
      661 cgctggcagt aacatctctt tcatccagtt cagcacatcc atttatttcc aacttgcata
      721 caagacatac tgagaaacta aaaaaatcgt taaaagtaaa gacacgttct ggacgggtat
      781 ctcgacctcc caaatataaa gctaaagatt ataagttcat aaaaacagag gatctggcgg
      841 atggtcatct gtcagattct gatgattact cagaactctg tgtggaagaa gatgaagatc
      901 agagggagag gcacgcactc tttgacttat cgagctgctc cctgaggccc aaaagcttta
      961 agtgtcagac ttgtgaaaag tcatatatag ggaagggggg actggcccga cattttaaac
     1021 ttaacccagg ccacggccag ttggaccccg agatggtgct gtctgagaaa gccagtggaa
     1081 gcaccctccg ggggtgcacg gaggaaagga cgctcagcct gacctccctg gggctgtcca
     1141 tgccagcgga tccatgtgag ggaggggccc gctcctgctt ggtgacagag tcagcacgcg
     1201 gtggcctgca gaatggtcag tctgtagacg ttgaagagac attgccatct gaaccagaaa
     1261 atggagctct tttgcgatca gagagatacc aaggacctag aagacgcgca tgctcagaga
     1321 cccttgcaga gtcccgcaca gctgtcctcc agcagagaag agctgctcag ctacctggtg
     1381 gccctgctgc ggcaggggag cagagggcgt cgccaagcaa agccaggctc aaggagttcc
     1441 tccagcagtg tgaccgggag gatctggtgg aattggctct gcctcagctg gctcaggttg
     1501 tgaccgtgta tgagtttctt ctgatgaagg ttgaaaaaga tcatctagca aagccttttt
     1561 tcccagctat atataaggaa tttgaagagt tgcataaaat ggttaagaaa atgtgccaag
     1621 attacctcag tagttctggt ctgtgttccc aggagaccct ggaaataaac aatgataagg
     1681 ttgctgagtc attaggaatc acagaattcc tacggaagaa agaaatacac ccagacaacc
     1741 ttggacccaa gcacctcagc cgagacatgg atggggagca gctagaggga gctagcagcg
     1801 agaagaggga acgtgaggct gcggaggagg gactggcctc agtgaaaagg cccagaagag
     1861 aagccctgtc caacgatacc actgaatctc ttgctgccaa cagcagaggc cgggagaagc
     1921 ccaggccctt gcatgctttg gccgctggtt tttcccctcc agtaaatgtg actgtctctc
     1981 cccgttctga agaaagccat acaacgacgg tttctggtgg caatgggagc gtgttccagg
     2041 cgggcccgca gcttcaggca ctggctaact tagaagccag gagggggtct ataggtgctg
     2101 ctctctcatc ccgggatgtc agtgggctgc ctgtttatgc tcagtcagga gagcctagga
     2161 ggctgaccca ggcacaggtg gcagcgtttc ctggagagaa tgctttggaa cactcttcag
     2221 accaggacac ctgggacagc ctgaggagcc cgggtttctg cagccctttg tcatctggtg
     2281 gtggagcaga gtccctgccg cctggggggc ctggacatgc agaggcagga cacctcggca
     2341 aggtttgtga cttccacctg aaccaccagc agcccagccc caccagcgtc ctgcctacag
     2401 aggtggcagc ccctccgctt gagaaaattt tgtctgtgga tagcgtggca gtggactgtg
     2461 cctacaggac tgtgcccaag ccagggcctc agcctggccc acatggatca ctattgactg
     2521 aagggtgtct cagaagcctt tcgggggact tgaaccggtt cccctgtggg atggaggtgc
     2581 actctggcca gagagaactg gagagcgtgg ttgctgtcgg cgaagccatg gcttttgaaa
     2641 tttccaatgg gagccatgag ttactgtctc agggacagaa gcagattttt attcagactt
     2701 ccgatgggct tatcttgtcc cctccaggta caatagtgtc tcaggaggag gacattgtca
     2761 cagtgactga tgcagagggg cgtgcctgcg gatgggcccg ctagaaggag ttcctctaga
     2821 agctgtggag tcggtcgtca ccgtggagcc agagccctca cagtgaagtg gagtcagatc
     2881 ctagattcgt ctgattttat ccagagaagg tctatggcaa gcaatgtata tttttctaat
     2941 gtgaatattg cacagatgaa ccttttattt ataaagaata atgtctttct gc
//
