LOCUS       NM_138466               1939 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 837 (ZNF837), transcript variant
            2, mRNA.
ACCESSION   NM_138466 XM_001725760 XM_001725797 XM_001726206 XM_001726207
            XM_375665 XM_938741
VERSION     NM_138466.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1939)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC012313.7, BX374687.2 and BC012365.1.
            
            On Nov 22, 2018 this sequence version replaced NM_138466.1.
            
            Transcript Variant: This variant (2) uses an alternate splice site,
            compared to variant 1, and is protein-coding.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853566.14648.1,
                                           SRR11853562.18495.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2150385, SAMEA2152798
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000597582.2/ ENSP00000471478.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AC012313.7         39230-39237         c
            9-66                BX374687.2         4-61
            67-339              BX374687.2         63-335
            340-1939            BC012365.1         194-1793
FEATURES             Location/Qualifiers
     source          1..1939
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..1939
                     /gene="ZNF837"
                     /note="zinc finger protein 837"
                     /db_xref="GeneID:116412"
                     /db_xref="HGNC:HGNC:25164"
     exon            1..90
                     /gene="ZNF837"
                     /inference="alignment:Splign:2.1.0"
     exon            91..200
                     /gene="ZNF837"
                     /inference="alignment:Splign:2.1.0"
     exon            201..1939
                     /gene="ZNF837"
                     /inference="alignment:Splign:2.1.0"
     CDS             230..1825
                     /gene="ZNF837"
                     /codon_start=1
                     /product="zinc finger protein 837"
                     /protein_id="NP_612475.1"
                     /db_xref="CCDS:CCDS46216.1"
                     /db_xref="GeneID:116412"
                     /db_xref="HGNC:HGNC:25164"
                     /translation="MEAPAQKAGQGGLPKADAQGASGAREKRPEEPRPLEEDRAGSRP
                     TQKGDLRGAAGGRTTPPGGGSRGCSLGVSPGPGTRHSAGTRPLVREPCGPTSSQNPEL
                     VIPEGLQAREGPCRSPARGGDCSRNSCLAWHRGAPAGETPPVCDPCPERIQNHPRTQL
                     CEVHTDCWPCQPGTGAPTCPRTPKPTSRGRNPLVEQPRACACGEAFAWRALRIPQERL
                     QATEEPRPCARCGKRFRPNQQQQAGKSPPVCPECGQTSRPRPIVPDPPAQRLYACDEC
                     GKAFTRTSSLLQHQRIHTGERPYECAECGKAFVRCSGLYRHQKTHSAERHRRGPVLAR
                     RAFRLGCPPCGDYSERSPRRGSGAGEKPYECADCAKAFGLFSHLVEHRRVHTGEKPYA
                     CPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQRAHTGERPYGCS
                     ECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHLRTHTGERPYACGDC
                     GRAFSQRSNLNEHRKRHGGRAAP"
     regulatory      1920..1925
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF837"
                     /note="hexamer: ATTAAA"
     polyA_site      1939
                     /gene="ZNF837"
                     /note="major polyA site"
ORIGIN      
        1 agtgccgcgg cggcccggag gtggcgggag gacggctccg cgctgcatgc ggggcgggga
       61 ccagggaccc gtgcgggccg cctccagaga atgaggctgc cagccttgag agcaccaccg
      121 ttacctggtt gaagagggga ggggaagtcc agcattggcc tctgcagcgt ggatctcccg
      181 gccaggctct cagctgtcag atcctacaac cagaactctg cgccccagga tggaggctcc
      241 agcccagaag gctgggcagg gaggactccc caaggccgat gcccagggtg cctccggggc
      301 ccgggagaag aggcccgagg agccgaggcc cctcgaagag gaccgagctg ggagccgccc
      361 cactcaaaag ggggacctgc gtggagcggc gggcggtagg acgactcccc caggcggggg
      421 ctcccggggc tgcagcctcg gggtgagccc cggcccgggg acccggcaca gcgccgggac
      481 cagacccctc gtgcgggagc cgtgcggccc cacctcttct cagaaccctg agctggttat
      541 ccccgagggg ctgcaagccc gggagggccc ctgtaggagc ccagcgcgtg gcggggactg
      601 cagcaggaac tcctgcctgg cgtggcatcg cggggcgccc gctggggaga cgccacccgt
      661 gtgtgacccc tgtccggagc ggatccagaa ccacccccgg actcaactgt gtgaggtcca
      721 cacggactgt tggccgtgcc aaccagggac tggcgctccg acctgcccga ggaccccaaa
      781 gccgacctcc cgcgggagga accccttggt ggagcagccc cgggcttgcg cgtgcggcga
      841 ggcctttgcg tggagggccc tgcggatccc ccaggagagg ctgcaggcga cggaggagcc
      901 ccgtccgtgt gcccggtgcg ggaagcgctt ccgccccaac cagcagcagc aggcgggcaa
      961 gagtccccca gtgtgtcctg agtgcggcca aacctcgcga cctcgcccta ttgtccccga
     1021 ccccccggcc cagcgactgt acgcttgcga cgagtgcggc aaggccttca cgcgcacctc
     1081 cagcctgctg cagcaccagc gcatccacac gggcgagcgg ccctacgagt gcgccgagtg
     1141 cggcaaggcc ttcgtgcgct gctccggcct gtaccgccac cagaagacgc actcggccga
     1201 gcgccaccgg cgtggccccg tcctggcgcg gcgcgccttc cggctggggt gcccgccctg
     1261 cggggactac agcgagcgga gtccccgacg ggggtcggga gccggggaga agccgtacga
     1321 gtgcgccgac tgcgccaagg ccttcgggct gttctcgcac ctcgtggagc accggcgcgt
     1381 gcacaccggc gagaagccct acgcgtgccc cgagtgcggc aaggccttca accagcgctc
     1441 gaacctgagc cggcaccagc gcactcacag cagcgccaag ccctacgcgt gcccactgtg
     1501 cgaaaaggcc ttcaagggcc gctcgggcct ggtgcaacac cagcgcgcgc acaccggcga
     1561 gcggccctat ggctgctccg agtgcggaaa gaccttccgc ggctgctccg agctgcgcca
     1621 gcacgagcgc ctgcactcgg gcgagaagcc ctacatctgc cgcgactgcg gcaaggcctt
     1681 cgtgcgcaac tgcagcctgg tgcgccacct gcgcacgcac acgggcgagc ggccctacgc
     1741 gtgcggagat tgcggccgcg ccttcagcca acgctccaac ctcaacgagc accggaagcg
     1801 gcacgggggc cgcgccgcgc cttgactgca gggagccgag agtcgacgcg tcgcccaagc
     1861 gaaccctgcg tcgaggaggg gcctttgtcc cggaaaaccc accaacgttt gtaactttga
     1921 ttaaacttca ctttgtaca
//
