LOCUS       NM_001037232            5032 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens zinc finger protein 829 (ZNF829), transcript variant
            2, mRNA.
ACCESSION   NM_001037232 XM_375606
VERSION     NM_001037232.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5032)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 5032)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB031896.1, BC107132.1, AC008733.9 and BX538288.1.
            
            On May 20, 2020 this sequence version replaced NM_001037232.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR, lacks a
            portion of the 5' coding region, and uses a downstream start codon,
            compared to variant 1. The encoded isoform (2) is shorter at the
            N-terminus, compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074967.644108.1,
                                           SRR18074968.3906012.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267750 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000391711.8/ ENSP00000429266.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-109               DB031896.1         1-109
            110-1805            BC107132.1         1-1696
            1806-4236           AC008733.9         61392-63822         c
            4237-5032           BX538288.1         4183-4978
FEATURES             Location/Qualifiers
     source          1..5032
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.12"
     gene            1..5032
                     /gene="ZNF829"
                     /note="zinc finger protein 829"
                     /db_xref="GeneID:374899"
                     /db_xref="HGNC:HGNC:34032"
     exon            1..281
                     /gene="ZNF829"
                     /inference="alignment:Splign:2.1.0"
     exon            282..403
                     /gene="ZNF829"
                     /inference="alignment:Splign:2.1.0"
     CDS             366..1664
                     /gene="ZNF829"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="zinc finger protein 829 isoform 2"
                     /protein_id="NP_001032309.2"
                     /db_xref="CCDS:CCDS42557.1"
                     /db_xref="GeneID:374899"
                     /db_xref="HGNC:HGNC:34032"
                     /translation="MPHSPLISIPHVWCHPEEEERMHDELLQAVSKGPVMFRDVSIDF
                     SQEEWECLDADQMNLYKEVMLENFSNLVSVGLSNSKPAVISLLEQGKEPWMVDRELTR
                     GLCSDLESMCETKILSLKKRHFSQVIITREDMSTFIQPTFLIPPQKTMSEEKPWECKI
                     CGKTFNQNSQFIQHQRIHFGEKHYESKEYGKSFSRGSLVTRHQRIHTGKKPYECKECG
                     KAFSCSSYFSQHQRIHTGEKPYECKECGKAFKYCSNLNDHQRIHTGEKPYECKVCGKA
                     FTKSSQLFLHLRIHTGEKPYECKECGKAFTQHSRLIQHQRMHTGEKPYECKQCGKAFN
                     SASTLTNHHRIHAGEKLYECEECRKAFIQSSELIQHQRIHTDEKPYECNECGKAFNKG
                     SNLTRHQRIHTGEKPYDCKECGKAFGSRSDLIRHEGIHTG"
     exon            404..461
                     /gene="ZNF829"
                     /inference="alignment:Splign:2.1.0"
     exon            462..588
                     /gene="ZNF829"
                     /inference="alignment:Splign:2.1.0"
     exon            589..684
                     /gene="ZNF829"
                     /inference="alignment:Splign:2.1.0"
     exon            685..5032
                     /gene="ZNF829"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5008..5013
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF829"
                     /note="hexamer: TATAAA"
     polyA_site      5032
                     /gene="ZNF829"
                     /note="major polyA site"
ORIGIN      
        1 agaacacatc tgctttcctg tgtgagggtg aggcttgggc cgggttcccc gggaggctca
       61 tctccattgc gcagcgctac ggcgacccgc aactccgagg ctcggctgga tgttgagagt
      121 tgagggagca gccgtttcgg gtgggcccag gcgaggagct gacaggaatc ggcgtgggtc
      181 ccgctctgga ctacatttcc cagagggcct ggtggcctgc cacttttctc gcaggaattc
      241 gaacgtttcg tcactcctgg cgggaccctt agatctggga ggaaacctct ctgaggtctg
      301 gtcagattcc aaccctggac agcagtgaac acaacctttc ccctgagcca ctggaattgg
      361 acagaatgcc ccattctcct ctgatctcca ttcctcatgt gtggtgtcac ccagaagagg
      421 aggaaagaat gcatgatgaa cttctacaag cagtatccaa ggggccggtg atgttcaggg
      481 atgtttccat agacttctct caagaggaat gggaatgcct ggacgctgat cagatgaatt
      541 tatacaaaga agtgatgttg gagaatttca gcaacctggt ttcagtggga ctttccaatt
      601 ctaagccagc tgtgatctcc ttattggaac aaggaaaaga gccctggatg gttgatagag
      661 agctgactag aggcctgtgt tcagatctgg aatcaatgtg tgagaccaaa atattatctc
      721 taaagaagag acatttcagt caagtaataa ttacccgtga agacatgtct acttttattc
      781 agcccacatt tcttattcca cctcaaaaaa ctatgagtga agagaaacca tgggaatgta
      841 agatatgtgg aaagaccttt aatcaaaact cacaatttat ccaacatcag agaattcatt
      901 ttggtgaaaa acactatgaa tctaaggagt atgggaagtc ctttagtcgt ggctcactcg
      961 ttactcgaca tcagaggatt cacactggta aaaaacccta tgaatgtaag gaatgtggca
     1021 aggcttttag ttgtagttca tatttttctc aacatcagag gattcacact ggtgagaaac
     1081 cctatgaatg taaggaatgt ggaaaagcct ttaagtattg ctcaaacctt aatgatcatc
     1141 agagaattca cactggtgag aaaccctatg aatgtaaagt atgtggaaaa gcctttacta
     1201 aaagttcaca actttttcta catctgagaa ttcatactgg tgagaaacct tatgaatgta
     1261 aagaatgtgg gaaagccttt actcaacact caaggcttat tcagcatcag agaatgcata
     1321 ctggtgagaa accttatgaa tgtaagcagt gtgggaaggc ctttaatagt gcctcaacac
     1381 ttactaacca tcacagaatt catgctggtg agaagctcta tgaatgtgaa gaatgtagaa
     1441 aggcctttat tcagagctca gaacttattc aacatcagag aatccataca gatgaaaaac
     1501 catatgaatg taatgaatgt gggaaggcct ttaataaagg ctcaaatctt actcgacatc
     1561 agagaattca cactggtgag aaaccctatg actgtaagga atgtggaaag gcttttggta
     1621 gtcgctctga cctcattcgc catgagggaa ttcatactgg ttgaatgaca gtaaagtaag
     1681 accattttgt taacctttat aataattttt ttaaaacagg taaggagaac aaattaggat
     1741 acatattatc aaaggttctc ctatgtattc gtttttaaac gatacgataa caaagtacca
     1801 agtaccaaaa ccttggtggc ttaaaacaag agaaatttat tctctcatag tttagagcct
     1861 ggaaatctaa actcaagggt gctgatcgtt ttggttcctt ctgaggactc tgaggatctg
     1921 ttctatgcct ttttcctaac ctctgttaac agctggcagt ccttggcatt ccatggcttt
     1981 tacatacacc attccaatct ctgcctccat cttcacattg cattctcgct gtgtatctct
     2041 gtgtatgtct tttatttgga caccagtcag gttagattgg ggttacctgg tgacctcatc
     2101 ttaacttgat tatatctgcc aagaccctgt ttccaagtaa ggtcacattt accggtacca
     2161 ggggttagga cttcagcata tctttttagg ggatacagtt caacccataa taccctgtta
     2221 gaatgatttt gtctaatata tttgtaattt ccttttatac ataagttgtt agtcaaattt
     2281 attttatttt attttatttt gagacagagt ctcgctctgt tgcccaggct ggagtgcagt
     2341 ggtgtgatct cagctcactg caacctccag ctcctgagtt caagcgattc ttgtgcctca
     2401 gcctctcaag tagttgggat tacaggcatg cgccaccatg cccggctaat tttttttttt
     2461 tttttttttg tatttttagt agcgacgggg tttcaccatg ttggccaggc tggtcttgaa
     2521 ctcctgactt caagtgatct gcccgcctca gcctcccaaa gtgctgggat tacagacgtg
     2581 agccaccgtg atggccaaaa cagactttat accaacaaaa attaaaaagg acaaagaagg
     2641 tcatttataa tgataaagga taaattcaac aagaagataa aacaatccta aatatgtatg
     2701 cacccaacac tgcaacaccc agatccataa cacagatact actagaccta agaaaagaga
     2761 tagacagcaa tacaacaata gcaggggact tcaccactcc attgacagca ctagacagat
     2821 cactgggaca gaaatcaaca aagaaactct ggacttaaat tggactctac accaaatgga
     2881 cccaacagac atctgaagaa cattctaccc aacaaccaca gaatatatac tcttctcttc
     2941 tgtgcatgga acattctcaa aaataggtca tatactggac cacaaagcaa gtatcaataa
     3001 attttaaaaa aacaaaatca tatctaacat cttctctgac catagtggaa taaaactaga
     3061 tatcaatacc aagaggaact ctcaaaacag atacatggaa tttaaacagc ttgctcctga
     3121 atgatttttg gatcaatgat gaaactaagg tggaaattta aaattttttg aaataaatga
     3181 aaatagagac aaaacacatg aaaacatctg agatacagca aaagcagtgc taagagagga
     3241 ttttatagca ttaaatgcct acaccaaaaa gatagaaaaa tctcaaatga atagcctaac
     3301 gtcacatctc aaggaactag gaaaaaacaa aacaaactca acccaaagct ggcagaagaa
     3361 aagcaataac aaatatcaga gcaggcaaaa atgagactga gaacaaagga atgcaaaaga
     3421 tcaataaaag aaaaagttgg ttctttgcaa agataaaact gacagaccac tagctagatt
     3481 aaccaagaaa aaaagaagat tcaaataaat acaatcagaa atgataaggt gatattataa
     3541 ctgataacac agacatataa aatatcagca gaaactatat gcacatatta gaaaacctag
     3601 aggaagtgga taaattccta gaaacacata accttccaag attgaaccag ggagaaatag
     3661 gaatcctcaa cagactactg agtattgaaa ttgaatcagt aatagaaaaa aatcttgcaa
     3721 aaacaaaaag cccaggacca gacagattca cagctgaatt ctactagaca tgcaaggaag
     3781 aactagtaac agcactattg aaactattcc aaaaattata ggagggaatc ctccctaact
     3841 cattctacaa agccagtatc atcctgatac tgaagccagg caaggataaa acacacaaaa
     3901 aaactacaag ccaatatccc tgatgaaaat agacacaaaa atcttcagca aaatactagc
     3961 aaaccaaatc aaacagtaca taaaaaagat agtaacagca cagtcaagtg gattttattc
     4021 ctggggtgta aggatggctc aacatatgca actcaataca tgattcatca catacacaga
     4081 attaaaaata agccaggcac tcacacctgt aatcccagca ctttgcaagg ccaaggcggg
     4141 cagatcacat gatgtcaaga gtttgagacc agtctggctg acatggcgaa accctgtctc
     4201 tactaaaaat agaaaaattg gctgggcatg gtggcaggca ctgtagtccc agctacttgg
     4261 gaggctgagg caggagaatt acttgaacct gagaagcgga ggttgcagtg agctgagata
     4321 gtgccattgc actccagcct gggcaacaga gcaaattgct tgaatgtggg aggtggaggt
     4381 tgcagtgagc cgagattatg ccattgcact ccagccgggg gagcaacaaa gccagactcc
     4441 atctcaaaaa aaaaccaaaa aaaatcctat ttagtacaag gtacattatt taggtaatga
     4501 gtccattaaa agccaacact ttccccacta cactatatgt gtatgtaaca caactgccct
     4561 tgtaacttcc taaacctata attaagaaac aataaaaggc aaattaagaa tgctttttta
     4621 aaaggtgggg gcattatgct aataagttac tgtggatttc agagtgcaga gtagaaagat
     4681 cacaagaatt tagtgtggta ggtgggaaca gaaaatgggt gtataaattt tattgacgtg
     4741 ggagtactgg atattgtaga gacagatatc atcagggcaa ggagattaaa gatttttgca
     4801 ttgacggttt gacactatat tgtggtaata acactgtatg tgttgggaga tagaacagga
     4861 aacatcttcc ctggaatatg tatactatta aatgttttat caaacttttg atcaaacaag
     4921 acagcacaat ttataatttc atttctattt ctatgttatg agaaactgat catttattca
     4981 aatgtttaac aggcatgttc atgttactat aaactcttct gtttcaccat ca
//
