LOCUS       NM_001080493            2396 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 823 (ZNF823), transcript variant
            1, mRNA.
ACCESSION   NM_001080493 XM_375568
VERSION     NM_001080493.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2396)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2396)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   3  (bases 1 to 2396)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA519419.1 and BC052597.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001080493.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.1145580.1,
                                           SRR1803611.248105.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000341191.11/ ENSP00000340683.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                DA519419.1         64-88
            26-2396             BC052597.1         1-2371
FEATURES             Location/Qualifiers
     source          1..2396
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..2396
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /note="zinc finger protein 823"
                     /db_xref="GeneID:55552"
                     /db_xref="HGNC:HGNC:30936"
     exon            1..130
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1960
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /note="isoform 1 is encoded by transcript variant 1; ZFP
                     36 for a zinc finger protein; zinc finger protein ZFP-36"
                     /codon_start=1
                     /product="zinc finger protein 823 isoform 1"
                     /protein_id="NP_001073962.1"
                     /db_xref="CCDS:CCDS45981.1"
                     /db_xref="GeneID:55552"
                     /db_xref="HGNC:HGNC:30936"
                     /translation="MDSVAFEDVAVNFTQEEWALLGPSQKSLYRNVMQETIRNLDCIE
                     MKWEDQNIGDQCQNAKRNLRSHTCEIKDDSQCGETFGQIPDSIVNKNTPRVNPCDSGE
                     CGEVVLGHSSLNCNIRVDTGHKSCEHQEYGEKPYTHKQRGKAISHQHSFQTHERPPTG
                     KKPFDCKECAKTFSSLGNLRRHMAAHHGDGPYKCKLCGKAFVWPSLFHLHERTHTGEK
                     PYECKQCSKAFPFYSSYLRHERIHTGEKAYECKQCSKAFPDYSTYLRHERTHTGEKPY
                     KCTQCGKAFSCYYYTRLHERTHTGEQPYACKQCGKTFYHHTSFRRHMIRHTGDGPHKC
                     KICGKGFDCPSSVRNHETTHTGEKPYECKQCGKVLSHSSSFRSHMITHTGDGPQKCKI
                     CGKAFGCPSLFQRHERTHTGEKPYQCKQCGKAFSLAGSLRRHEATHTGVKPYKCQCGK
                     AFSDLSSFQNHETTHTGEKPYECKECGKAFSCFKYLSQHKRTHTVEKPYECKTCRKAF
                     SHFSNLKVHERIHSGEKPYECKECGKAFSWLTCLLRHERIHTGEKPYECLQCGKAFTR
                     SRFLRGHEKTHTGEKLYECKECGKALSSLRSLHRHKRTHWKDTL"
     exon            131..257
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /inference="alignment:Splign:2.1.0"
     exon            258..318
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /inference="alignment:Splign:2.1.0"
     exon            319..2396
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2374..2379
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /note="hexamer: ATTAAA"
     polyA_site      2396
                     /gene="ZNF823"
                     /gene_synonym="HSZFP36"
                     /note="major polyA site"
ORIGIN      
        1 ccctgcgctc tgagtcctgg ctctggcgct gagagagaga cgccctggaa ggtctgtatc
       61 agcgtctgtc gcgctgggac ccacactggc ttttaaggag gacacccgga cacctggaag
      121 ctgggaaatg gactcagtgg cctttgaaga tgtggctgtg aacttcacac aagaggagtg
      181 ggctttgctg ggtccatcac agaagagtct ctacagaaat gtcatgcagg aaaccattag
      241 gaacctggac tgtatagaaa tgaaatggga ggaccagaac attggagatc agtgccaaaa
      301 tgccaagaga aatctaagaa gtcatacatg tgaaattaaa gatgacagtc aatgtggaga
      361 aacttttggc cagattccag atagtattgt gaacaagaac actcctcgag taaatccatg
      421 tgacagtggt gagtgtggag aagtcgtctt gggtcattcg tctcttaatt gcaacatcag
      481 agttgacact ggacacaaat catgtgagca tcaggaatat ggagagaagc catatacaca
      541 taaacaacgt gggaaagcca tcagtcatca gcactccttc cagacacatg aaaggccccc
      601 caccggaaag aaacccttcg attgtaaaga atgtgcaaaa acctttagtt ctcttggaaa
      661 cctccgaaga cacatggcgg cacaccatgg agatggacct tataaatgta agttgtgtgg
      721 gaaagccttt gtttggccca gtttatttca tttgcacgaa agaacacaca ctggagagaa
      781 accgtatgaa tgtaagcagt gttctaaagc ctttcctttt tacagttcct atctaagaca
      841 tgaaagaatc cacacgggag agaaagcgta tgaatgtaag cagtgttcca aagcctttcc
      901 tgattacagt acctatctaa gacatgagag aactcacacc ggagagaaac cctataaatg
      961 tacacaatgt gggaaagcct tcagctgtta ctattacact cgactacatg aaaggactca
     1021 cacgggagaa caaccctatg catgtaagca atgtgggaaa acgttttatc atcacacaag
     1081 ctttcgaaga cacatgataa ggcacactgg agacggacca cataaatgta agatatgtgg
     1141 gaaaggcttt gattgtccta gttcagttcg aaatcatgaa actactcaca ctggagagaa
     1201 accctatgaa tgtaagcagt gtgggaaagt gttatctcat agctcgagct ttcgaagtca
     1261 catgataaca cacacaggag atggacccca gaaatgcaag atatgtggga aagcctttgg
     1321 ttgtcccagt ttatttcaaa gacatgaaag gactcacact ggagagaaac cctatcaatg
     1381 taaacaatgt ggtaaagcct tcagtcttgc cggttccctt cgaagacatg aagcaactca
     1441 cactggagtg aaaccctata aatgtcagtg tgggaaagcc tttagtgatc tctcttcctt
     1501 tcaaaatcat gagacaactc acactggaga gaagccatat gagtgtaagg aatgtgggaa
     1561 agcattcagt tgtttcaaat acctttctca acataaaagg acccacacag tagaaaaacc
     1621 ttatgagtgt aaaacatgta gaaaagcctt cagtcatttc agtaacttaa aagtccatga
     1681 aaggattcac tctggagaga agccatatga atgtaaggaa tgtggaaaag cattctcttg
     1741 gctcacttgc cttctacgac atgaaagaat tcacactgga gagaaaccct atgaatgtct
     1801 acaatgtggt aaagccttca ctcgttcccg tttccttcga ggacatgaaa aaactcacac
     1861 tggagagaag ctgtatgaat gtaaggaatg tgggaaagca ttgagttctc tccgttcctt
     1921 gcatagacat aaaaggactc actggaaaga tactctctaa atgtatggaa tgtgggaaaa
     1981 cattcagtac tttaatttca gaaacttgaa agaactcact ttggagatag accctatgaa
     2041 tgtaaacatg ggataaagcc ttaagtagtt tcaatttttt taaatacagt tatcccccaa
     2101 tatattgcag gggattggtt ccagcaccct ctaaatccac agatgccaag tcctttgtta
     2161 tatggcatat ttgcatgtaa cctatgcata tcttccagta tactgtgtaa atcatctcta
     2221 gatgactttt aatacctcat gcattgtaaa agctatgtaa atagttgttt gattgtattg
     2281 tttagagaat catgacaaga aaaatagtct ctacatgttc gatgcagaca caaccattgc
     2341 aggcccacct acgtggtata tgtcacccag aacattaaaa tttgttttaa cattca
//
