LOCUS       NM_001202473            2650 bp    mRNA    linear   PRI 10-JUL-2022
DEFINITION  Homo sapiens ZNF816-ZNF321P readthrough (ZNF816-ZNF321P), mRNA.
ACCESSION   NM_001202473
VERSION     NM_001202473.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2650)
  AUTHORS   Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y,
            Fujikake T, Takeda T and Taylor TD.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS One 5 (10), e13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010328.4, DB207639.1 and AC010487.7.
            
            On Aug 13, 2020 this sequence version replaced NM_001202473.1.
            
            Summary: This locus represents naturally occurring read-through
            transcription between the zinc finger protein 816 (ZNF816) gene and
            the zinc finger protein 321 (ZNF321) pseudogene on chromosome 19.
            The read-through transcript encodes a KRAB domain-containing
            protein that shares sequence identity with the upstream gene
            product, but it contains a distinct C-terminus encoded by exon
            structure from the downstream pseudogene. [provided by RefSeq, Jan
            2011].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB207639.1, SRR7346977.786386.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 125893, 399669
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                AC010328.4         183320-183377
            59-598              DB207639.1         1-540
            599-2650            AC010487.7         78175-80226         c
FEATURES             Location/Qualifiers
     source          1..2650
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.41"
     gene            1..2650
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="ZNF816-ZNF321P readthrough"
                     /db_xref="GeneID:100529240"
                     /db_xref="HGNC:HGNC:38879"
     exon            1..165
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /inference="alignment:Splign:2.1.0"
     exon            166..243
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /inference="alignment:Splign:2.1.0"
     CDS             181..882
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="ZNF816-ZNF321 readthrough; ZNF816-ZNF321
                     read-through transcript"
                     /codon_start=1
                     /product="ZNF816-ZNF321 protein"
                     /protein_id="NP_001189402.1"
                     /db_xref="GeneID:100529240"
                     /db_xref="HGNC:HGNC:38879"
                     /translation="MLREEATKKSKEKEPGMALPQGRLTFRDVAIEFSLEEWKCLNPA
                     QRALYRAVMLENYRNLEFVDISSKCMMKEFSSTAQGNTEVIHTGTLQRHESHHIRDFC
                     FQEIEKDIHNFEFQWQEEERNGHEAPMTEIKELTGSTDRHDQRHAGNKPIKDQLGSSF
                     HSHLPELHIFQPEWKIGNQVEKSIINASLILTSQRISCSPKTRISNNYGNNSLHSSLP
                     IQKLGSTHERKIFPM"
     exon            244..370
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /inference="alignment:Splign:2.1.0"
     exon            371..2650
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      882
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="major polyA site"
     regulatory      956..961
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="hexamer: TATAAA"
     polyA_site      987
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
     regulatory      1013..1018
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="hexamer: AATAGA"
     polyA_site      1036
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
     regulatory      1142..1147
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="hexamer: AACAAG"
     polyA_site      1165
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
     regulatory      1919..1924
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="hexamer: AATAAT"
     polyA_site      1936
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
     regulatory      1945..1950
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
                     /note="hexamer: ATTAAA"
     polyA_site      1970
                     /gene="ZNF816-ZNF321P"
                     /gene_synonym="ZNF816-ZNF321"
ORIGIN      
        1 acagacccgg aagcggatgg cgtggactga aagttgcacg gcggcgtgtg cgtttcctag
       61 ttgtctggtg ctgctatata ggggacgtgg ggtccccaca gacctgcagg ttccggcccc
      121 tcttttctca acccagagca aattgaaacg tccgggtgag agtccgattt ccaaagactc
      181 atgttacgtg aggaagccac caagaagagc aaagaaaagg agccagggat ggctcttcct
      241 cagggacgct tgactttcag ggatgtggct atagagttct ctttggagga gtggaaatgc
      301 ctgaaccctg cacagagggc tttatacagg gctgtgatgt tggagaacta caggaacctg
      361 gagtttgtgg atatctcttc caaatgcatg atgaaggagt tctcatccac agcgcaaggc
      421 aatacagaag tgatccacac agggacattg caaagacatg aaagtcatca cattagagat
      481 ttttgcttcc aggaaattga gaaagatatt cataactttg agtttcagtg gcaagaagag
      541 gaaaggaatg gtcacgaagc acccatgaca gaaatcaaag agttgactgg tagtacagac
      601 cgacatgatc aaaggcatgc tggaaacaag cctattaaag atcagcttgg atccagcttt
      661 cattcgcatc tgcctgaact ccacatattt cagcctgaat ggaaaattgg taatcaagtt
      721 gagaagtcta tcatcaatgc ctccttaatt ttgacatccc aaagaatttc ttgtagtccc
      781 aaaacccgta tttctaataa ctatgggaat aattccctcc attcttcatt acccatacaa
      841 aaattgggaa gtacacatga gagaaaaatc tttccaatgt aatgagagtg gcaaatcctt
      901 taattatagc taactcttaa ggaaatatca gataatccat ttaggataga aacaatataa
      961 atgtgaggta tgtgacaagg tctttaatca gaattgattc cttgtatgcc ataatagatg
     1021 tcacactggt aagaaacctt acagttgtta tgagtgtggc aagaccttca gtcagacgtc
     1081 atcctttaca tgctatcgta gacttcatac tggagggaaa ccttacaagt gtagtgagca
     1141 taacaagacc tttggttgaa attcagccct tgtaattcat aaggcaattc atactggaga
     1201 gaatccttgc aagtgtaatg aatgtggcaa ggtttttaat cagaaagcac accttgcacg
     1261 tcatcataga cttcatacta gagagaagcc ttacaaatgt gaagaatgtg aaaaagtttt
     1321 cagtcgcaaa tcacatcttg aaagacaaaa cttaaaagag gtggcgttgc ccttgttttt
     1381 gagaatgccc tactgtgtaa gtggtagtgt tctttctttt tttttttttt ttaagacgga
     1441 gtctcacctg agcgagcctc tgcactggcc ttatttatta ttgttattaa ttttttgttt
     1501 ttgagacgga gtttcactct tattgcccag gctggagtgc aatggtgcaa tcttggctca
     1561 ctgcaccctc tgtctgttgg gctcaagcgt ttctcttgcc tcagcctccc aagtagctgg
     1621 gactacaggt gcatgccacc acgcctggtt aatttttgta tttatagtgg agatggggtt
     1681 tctccatatt ggtcaggctg gtcttgaacc cttgacctca ggtcatccac ccgcctcggc
     1741 cttccaaaac gctggattta caggcttgag ccacgcgtcc ggcctgaagt ggtatttttt
     1801 agaaagtaac taaacctttt ttcagtttaa tgacccaggg atgtatttct gaaggacttg
     1861 ggagcgatcc ttttaaggca aacaagggag atagtacctg tatcttagta ggaaattaaa
     1921 taattcaaac atcaaatgtt tcaaattaaa agctaccgac ctttaaataa ttctgagcct
     1981 tgagaggaac gtggtcatgc aacaagagtc cagtggcatg caggcacaag gttttttctt
     2041 ttttgttttt tgtttttttt tgagacagtc tcgctctgtc gcccaagctg aagtgcagtg
     2101 gtgcgatctc agctcactgc aagctccgcc tcctgggttc acgtcatttt cctgtctcag
     2161 cctccccagt agctgggact ccaggcaccc accaccactc ccggctaatt ttttgtattt
     2221 ttagtacaga cagggtttca ctgtgttagc caggatggtc ttgatctcct gaccttgtga
     2281 tccacccacc tcagcctccc aaagtgctgg gattacaggc atgaatgacc gcgcccagcc
     2341 gcaggcgcaa cttttttgag ttttcctggc caggcgcagt ggctcaagcc tgtaatccca
     2401 gcattttggg aggccgaggt gggcggatca cttgaggtca ggagttagaa accagcctgg
     2461 ccaacgtggt gaaaccccgt ctccagtaaa catacaaagc cattacaggg catggtgggg
     2521 cacgcctgta ttcccagcta cttgggaggc tgaggcagga gaactgcttg atccggggag
     2581 gtggaagttg cagtgggcca agatcatgcc actgcacccc agcctgggca acagagcaag
     2641 actccgtacc
//
