LOCUS       NM_001202457            2560 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens zinc finger protein 816 (ZNF816), transcript variant
            3, mRNA.
ACCESSION   NM_001202457
VERSION     NM_001202457.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Sun,L.D., Cheng,H., Wang,Z.X., Zhang,A.P., Wang,P.G., Xu,J.H.,
            Zhu,Q.X., Zhou,H.S., Ellinghaus,E., Zhang,F.R., Pu,X.M., Yang,X.Q.,
            Zhang,J.Z., Xu,A.E., Wu,R.N., Xu,L.M., Peng,L., Helms,C.A.,
            Ren,Y.Q., Zhang,C., Zhang,S.M., Nair,R.P., Wang,H.Y., Lin,G.S.,
            Stuart,P.E., Fan,X., Chen,G., Tejasvi,T., Li,P., Zhu,J., Li,Z.M.,
            Ge,H.M., Weichenthal,M., Ye,W.Z., Zhang,C., Shen,S.K., Yang,B.Q.,
            Sun,Y.Y., Li,S.S., Lin,Y., Jiang,J.H., Li,C.T., Chen,R.X.,
            Cheng,J., Jiang,X., Zhang,P., Song,W.M., Tang,J., Zhang,H.Q.,
            Sun,L., Cui,J., Zhang,L.J., Tang,B., Huang,F., Qin,Q., Pei,X.P.,
            Zhou,A.M., Shao,L.M., Liu,J.L., Zhang,F.Y., Du,W.D., Franke,A.,
            Bowcock,A.M., Elder,J.T., Liu,J.J., Yang,S. and Zhang,X.J.
  TITLE     Association analyses identify six new psoriasis susceptibility loci
            in the Chinese population
  JOURNAL   Nat Genet 42 (11), 1005-1009 (2010)
   PUBMED   20953187
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA473052.1, BC105930.1, BC063805.1 and AC010487.7.
            
            On Feb 27, 2020 this sequence version replaced NM_001202457.2.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Variants 1, 2 and 3 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105739.1, SRR14038197.2442654.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267750, SAMN03267774
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000444460.7/ ENSP00000403266.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               DA473052.1         31-143
            114-2503            BC105930.1         1-2390
            2504-2555           BC063805.1         2637-2688
            2556-2560           AC010487.7         100425-100429       c
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.41"
     gene            1..2560
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /note="zinc finger protein 816"
                     /db_xref="GeneID:125893"
                     /db_xref="HGNC:HGNC:26995"
     exon            1..155
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /inference="alignment:Splign:2.1.0"
     exon            156..233
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..2126
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /note="zinc finger protein 816A"
                     /codon_start=1
                     /product="zinc finger protein 816"
                     /protein_id="NP_001189386.1"
                     /db_xref="CCDS:CCDS33096.1"
                     /db_xref="GeneID:125893"
                     /db_xref="HGNC:HGNC:26995"
                     /translation="MLREEATKKSKEKEPGMALPQGRLTFRDVAIEFSLEEWKCLNPA
                     QRALYRAVMLENYRNLEFVDSSLKSMMEFSSTRHSITGEVIHTGTLQRHKSHHIGDFC
                     FPEMKKDIHHFEFQWQEVERNGHEAPMTKIKKLTGSTDRSDHRHAGNKPIKDQLGLSF
                     HSHLPELHMFQTKGKISNQLDKSIGASSASESQRISCRLKTHISNKYGKNFLHSSFTQ
                     IQEICMREKPCQSNECGKAFNYSSLLRRHHITHSREREYKCDVCGKIFNQKQYIVYHH
                     RCHTGEKTYKCNECGKTFTQMSSLVCHRRLHTGEKPYKCNECGKTFSEKSSLRCHRRL
                     HTGEKPYKCNECGKTFGRNSALVIHKAIHTGEKPYKCNECGKTFSQKSSLQCHHILHT
                     GEKPYKCEECDNVYIRRSHLERHRKIHTGEGSYKCKVCDKVFRSDSYLAEHQRVHTGE
                     KPYKCNKCGRSFSRKSSLQYHHTLHTGEKPYTCNECGKVFSRRENLARHHRLHAGEKP
                     YKCEECDKVFSRRSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLANHTRVHTGEKPYK
                     CNKCAKVFNQKGILAQHQRVHTGEKPYKCNECGKVFNQKASLAKHQRVHTAEKPYKCN
                     ECGKAFTGQSTLIHHQAIHGCRETLQM"
     exon            234..360
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /inference="alignment:Splign:2.1.0"
     exon            361..2560
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2533..2538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /note="hexamer: AATAAA"
     regulatory      2544..2549
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /note="hexamer: TATAAA"
     polyA_site      2555
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /note="major polyA site"
     polyA_site      2560
                     /gene="ZNF816"
                     /gene_synonym="ZNF816A"
                     /note="major polyA site"
ORIGIN      
        1 acagacccgg aagcggatgg cgtggactga aagttgcacg gcggcgtgtg cgtttcctag
       61 ttgtctggtg ctgctatata ggggacgtgg ggtccccaca gacctgcagg ttccggcccc
      121 tcttttctca acccagagca aattgaaacg tccgggattt ccaaagactc atgttacgtg
      181 aggaagccac caagaagagc aaagaaaagg agccagggat ggctcttcct cagggacgct
      241 tgactttcag ggatgtggct atagagttct ctttggagga gtggaaatgc ctgaaccctg
      301 cacagagggc tttatacagg gctgtgatgt tggagaacta caggaacctg gagtttgtgg
      361 atagctcttt aaaatccatg atggagttct catcaaccag gcacagtatt acaggagaag
      421 tgatccacac agggacgttg caaagacata aaagtcatca cattggagat ttttgcttcc
      481 cagaaatgaa gaaagatatt catcactttg agtttcagtg gcaagaagtt gaaagaaatg
      541 gccatgaagc acccatgaca aaaatcaaaa agttgactgg tagtacagac cgaagtgatc
      601 acaggcatgc tggaaacaag cctattaaag atcagcttgg attaagcttt cattcgcatc
      661 tgcctgaact ccacatgttt cagactaaag ggaaaattag taaccaattg gacaagtcta
      721 tcggtgcttc ctcagcttca gaatcccaaa gaatttcttg taggctcaaa actcatattt
      781 ctaataagta tgggaagaat ttcctccatt cttcattcac acaaatacag gaaatatgca
      841 tgagagaaaa accttgccaa agtaatgagt gtggcaaagc ctttaattat agctcactct
      901 taaggagaca ccacataacc cattcaagag agagagaata taaatgtgat gtatgtggca
      961 agatctttaa tcagaagcaa tacattgtat atcatcatag atgtcacact ggtgagaaaa
     1021 cttacaagtg taatgagtgt gggaagacct tcactcagat gtcatccctt gtatgccatc
     1081 gtagacttca tactggagag aaaccttaca agtgtaatga gtgtggcaag accttcagtg
     1141 agaagtcatc ccttagatgc catcgtagac ttcatactgg agagaaacct tacaagtgta
     1201 atgagtgtgg caagactttt ggtcgaaatt cagcccttgt aattcataag gcaattcata
     1261 ctggagagaa accttacaag tgtaatgagt gtggcaagac cttcagtcag aaatcatccc
     1321 ttcaatgcca tcatatactt cacactggag agaaacctta caaatgtgaa gaatgtgaca
     1381 atgtttacat tcgcagatca caccttgaaa gacataggaa gattcatact ggagagggat
     1441 catacaaatg taaggtttgt gacaaggttt tccggagtga ttcatacctt gcagaacatc
     1501 agagagttca tactggagag aaaccataca agtgtaataa atgtggcagg agtttcagtc
     1561 ggaagtcatc ccttcaatac catcatacac ttcacactgg agagaaacct tacacatgta
     1621 atgaatgtgg caaggttttt agtcgaagag aaaaccttgc acgtcatcat agacttcatg
     1681 ctggagagaa accttacaaa tgtgaagaat gtgacaaagt tttcagtcgc agatcacacc
     1741 ttgaaagaca taggagaatt catactgggg aaaaaccata caaatgtaag gtttgtgaca
     1801 aggctttccg gagtgattca tgccttgcaa accatacgag agttcatact ggagagaaac
     1861 cttacaagtg taataaatgt gcgaaggttt ttaatcaaaa aggaatcctt gcacaacatc
     1921 agagagttca tactggagag aaaccttaca agtgtaatga atgtggcaag gtttttaatc
     1981 aaaaagcaag ccttgcaaaa catcagagag ttcatactgc agagaaacct tacaagtgta
     2041 atgagtgtgg caaagccttt actggacagt caacacttat tcaccatcaa gcaatccatg
     2101 ggtgtaggga aactttacaa atgtaatgat tgtcacaaag tcttcagtaa tgctacaacc
     2161 attgcaaatc attacagaat ccatattgaa gagagatcta caagtgtaat aaatgtggca
     2221 aatttttcag acgtcattca taacttgtag ttcatcagtg aactcatact ggagagaaac
     2281 cttacaaata tcatgactgt gacaaggtct tcagtcaagc ttcatcctat gcaaaacata
     2341 gaattcatac aggagagaaa cctcacaagt gtgatgattg tggcaaagcc tttacttcat
     2401 gttcacacct cattagacat cagagaattc atactggaca gatgccttac aaatgtaagg
     2461 gtggcaaggt cttcactctg tggtcattcc atgcagaaca tcagaaaatt catttttgag
     2521 ataattgttc caaataaaat gaatataaaa aatcataaaa
//
