LOCUS       NM_007137              11230 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens zinc finger protein 81 (ZNF81), transcript variant 1,
            mRNA.
ACCESSION   NM_007137
VERSION     NM_007137.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11230)
  AUTHORS   Kleefstra,T., Yntema,H.G., Oudakker,A.R., Banning,M.J.,
            Kalscheuer,V.M., Chelly,J., Moraine,C., Ropers,H.H., Fryns,J.P.,
            Janssen,I.M., Sistermans,E.A., Nillesen,W.N., de Vries,L.B.,
            Hamel,B.C. and van Bokhoven,H.
  TITLE     Zinc finger 81 (ZNF81) mutations associated with X-linked mental
            retardation
  JOURNAL   J Med Genet 41 (5), 394-399 (2004)
   PUBMED   15121780
REFERENCE   2  (bases 1 to 11230)
  AUTHORS   Hamel,B.C., Smits,A.P., van den Helm,B., Smeets,D.F., Knoers,N.V.,
            van Roosmalen,T., Thoonen,G.H., Assman-Hulsmans,C.F., Ropers,H.H.,
            Mariman,E.C. and Kremer,H.
  TITLE     Four families (MRX43, MRX44, MRX45, MRX52) with nonspecific
            X-linked mental retardation: clinical and psychometric data and
            results of linkage analysis
  JOURNAL   Am J Med Genet 85 (3), 290-304 (1999)
   PUBMED   10398246
REFERENCE   3  (bases 1 to 11230)
  AUTHORS   Knight,J.C., Grimaldi,G., Thiesen,H.J., Bech-Hansen,N.T.,
            Fletcher,C.D. and Coleman,M.P.
  TITLE     Clustered organization of Kruppel zinc-finger genes at Xp11.23,
            flanking a translocation breakpoint at OATL1: a physical map with
            locus assignments for ZNF21, ZNF41, ZNF81, and ELK1
  JOURNAL   Genomics 21 (1), 180-187 (1994)
   PUBMED   8088786
REFERENCE   4  (bases 1 to 11230)
  AUTHORS   Marino,M., Archidiacono,N., Franze,A., Rosati,M., Rocchi,M.,
            Ballabio,A. and Grimaldi,G.
  TITLE     A novel X-linked member of the human zinc finger protein gene
            family: isolation, mapping, and expression
  JOURNAL   Mamm Genome 4 (5), 252-257 (1993)
   PUBMED   8507979
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL022578.1, AL591394.11 and
            Z98304.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 13, 2020 this sequence version replaced NM_007137.4.
            
            Summary: This gene encodes a protein that likely functions as a
            transcription factor. The protein contains an N-terminal KRAB
            domain and several C2H2-type zinc finger motifs. Mutations in this
            gene cause an X-linked form of intellectual disability (MRX45).
            Microduplication of a region of chromosome X including this gene
            has also been associated with other forms of intellectual
            disability. [provided by RefSeq, Jul 2017].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038191.3623078.1,
                                           SRR18074969.3710824.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000338637.13/ ENSP00000341151.7
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AL022578.1         76431-76516
            87-303              AL022578.1         85634-85850
            304-430             AL591394.11        24931-25057
            431-526             AL591394.11        32777-32872
            527-11230           Z98304.1           191502-202205       c
FEATURES             Location/Qualifiers
     source          1..11230
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.23"
     gene            1..11230
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /note="zinc finger protein 81"
                     /db_xref="GeneID:347344"
                     /db_xref="HGNC:HGNC:13156"
                     /db_xref="MIM:314998"
     exon            1..86
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /inference="alignment:Splign:2.1.0"
     exon            87..303
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..2235
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 81 isoform 1"
                     /protein_id="NP_009068.2"
                     /db_xref="CCDS:CCDS43933.1"
                     /db_xref="GeneID:347344"
                     /db_xref="HGNC:HGNC:13156"
                     /db_xref="MIM:314998"
                     /translation="MPANEDAPQPGEHGSACEVSVSFEDVTVDFSREEWQQLDSTQRR
                     LYQDVMLENYSHLLSVGFEVPKPEVIFKLEQGEGPWTLEGEAPHQSCSDGKFGIKPSQ
                     RRISGKSTFHSEMEGEDTRDDSLYSILEELWQDAEQIKRCQEKHNKLLSRTTFLNKKI
                     LNTEWDYEYKDFGKFVHPSPNLILSQKRPHKRDSFGKSFKHNLDLHIHNKSNAAKNLD
                     KTIGHGQVFTQNSSYSHHENTHTGVKFCERNQCGKVLSLKHSLSQNVKFPIGEKANTC
                     TEFGKIFTQRSHFFAPQKIHTVEKPHELSKCVNVFTQKPLLSIYLRVHRDEKLYICTK
                     CGKAFIQNSELIMHEKTHTREKPYKCNECGKSFFQVSSLLRHQTTHTGEKLFECSECG
                     KGFSLNSALNIHQKIHTGERHHKCSECGKAFTQKSTLRMHQRIHTGERSYICTQCGQA
                     FIQKAHLIAHQRIHTGEKPYECSDCGKSFPSKSQLQMHKRIHTGEKPYICTECGKAFT
                     NRSNLNTHQKSHTGEKSYICAECGKAFTDRSNFNKHQTIHTGEKPYVCADCGRAFIQK
                     SELITHQRIHTTEKPYKCPDCEKSFSKKPHLKVHQRIHTGEKPYICAECGKAFTDRSN
                     FNKHQTIHTGDKPYKCSDCGKGFTQKSVLSMHRNIHT"
     exon            304..430
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /inference="alignment:Splign:2.1.0"
     exon            431..526
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /inference="alignment:Splign:2.1.0"
     exon            527..11230
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /inference="alignment:Splign:2.1.0"
     regulatory      11201..11206
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /note="hexamer: AATAAA"
     polyA_site      11230
                     /gene="ZNF81"
                     /gene_synonym="dJ54B20.6; HFZ20; MRX45"
                     /note="major polyA site"
ORIGIN      
        1 ggaagcggct gcggttctcg ccggttctca gccggggttt gatagttgtc aggaggattc
       61 gacgttcagt gcccagggat gtggagagtt cttggagtct ctgcggagtc cctgggccag
      121 atctcacagt gaaagctgca ggatcttcct tctgacccca gcagtccccg ttgagtccac
      181 cgatcccact ggaattataa agttgtcagc aagaaagccc cagggctgaa gtccaagtcc
      241 gtcgggaaca tgccagctaa cgaggacgct ccccagccag gggaacatgg cagtgcctgt
      301 gaggtatcag tgtcatttga ggatgtgact gtggacttca gtagagagga gtggcagcaa
      361 ctggactcta ctcaaagacg cctgtaccag gatgtaatgt tggagaacta cagccacctg
      421 ctctcagtgg ggttcgaagt tcctaaacca gaggtcatct tcaagttgga gcaaggagag
      481 gggccatgga cattggaagg ggaagcccca catcagagct gttcagatgg gaaatttgga
      541 attaagcctt cccagaggag aatttctggg aaatctacat ttcatagtga aatggagggt
      601 gaagacacaa gagatgattc attatactct attttagaag aattgtggca agatgctgaa
      661 cagataaaga gatgtcagga aaaacacaac aaacttctga gtcgcactac tttcctcaat
      721 aagaaaatat tgaatacaga gtgggattat gaatataaag actttggaaa atttgttcat
      781 ccaagcccaa atctcattct ttcacagaaa agaccccata aacgtgattc atttgggaag
      841 agttttaagc ataatttaga cttacatatt cataataaaa gcaatgcagc aaagaacctg
      901 gataaaacta ttgggcatgg tcaagttttt acccagaact cttcttatag tcaccacgaa
      961 aatacacata caggagtgaa gttctgtgaa cgtaatcaat gtggaaaagt cctcagcctc
     1021 aaacactcac tcagtcaaaa tgtgaaattt cccattggag agaaagcaaa cacatgtact
     1081 gaatttggga agatcttcac ccagaggtca catttctttg ctcctcaaaa aattcatact
     1141 gtggaaaaac ctcatgagct tagcaaatgt gtaaatgttt ttacacagaa gccactactc
     1201 agtatatatc tgagagttca tagagatgaa aaactctaca tatgtactaa atgtgggaag
     1261 gccttcatcc agaattcaga attaattatg catgagaaaa ctcatactag agagaaaccc
     1321 tataaatgca atgaatgtgg gaaatcattt ttccaggtgt catctctact caggcatcag
     1381 acaactcata ctggagaaaa actctttgaa tgcagtgaat gtggtaaagg cttctccctg
     1441 aactcagccc tcaatataca tcagaaaatt cacactggag agagacatca caaatgcagt
     1501 gagtgtggga aagcctttac ccaaaaatca acactcagga tgcatcagag aattcataca
     1561 ggagagaggt cctatatctg tactcaatgt gggcaggcct tcatccagaa ggcacacttg
     1621 attgcacatc aaagaattca tactggagag aagccttatg aatgcagtga ctgtgggaaa
     1681 tctttccctt ctaagtcaca actccagatg cataagagaa ttcatacagg agagaaaccc
     1741 tatatatgca ctgaatgtgg gaaggctttc accaacaggt caaatctcaa tactcaccag
     1801 aagtctcata ctggagaaaa gtcttatata tgtgctgaat gtgggaaggc cttcaccgac
     1861 aggtcaaatt tcaataaaca ccagaccatt cacactggag agaaacccta tgtttgtgct
     1921 gattgtggga gggccttcat ccagaagtca gagttgatta cacatcagag aattcatact
     1981 acagagaagc cttataaatg tcctgactgt gagaaatcct tctccaagaa accacatctc
     2041 aaagtacatc aacgaattca cacaggggag aaaccatata tatgtgcaga atgtgggaaa
     2101 gccttcactg ataggtcaaa tttcaataaa catcagacaa ttcatactgg agataaaccg
     2161 tataaatgca gcgactgtgg aaaggggttc acccagaaat cagttctcag tatgcatcgc
     2221 aatattcata catgaaagta atcctgtttc ttgaaaatga gagccttata aggctgacaa
     2281 aagtcaggtc taactatata ttataaaatt catccaagac agatcctata tgaatacatt
     2341 gtataaggaa aagcatcagg ctatctcact tgagatggaa aaaaattatt cagaagaaac
     2401 tctcttaaaa atgcattgaa ggagagagaa tttgcacagc ctcatgaaat atagtaaaag
     2461 tcatactggg aaaaatgttg tcagtttggt gtgttaggaa aagccttcct atagaaagta
     2521 ttataagtta aattgttacc aaattcttta taggaaggag agtgcaaaat tatgtaaatg
     2581 atggtcaggt ttactgtgtt atattaagca atttaaagtg ataacaaaat gaaaggtagt
     2641 gcagcaaaat aatataactg gtgagtagac ctactttcag ttccataggg tgtttgtggc
     2701 agaacacagt gcagaacagg aggaatatta catttttttt caaatttaga ataattatgt
     2761 ccatcaaatg tttcttactg aatatgtcta tcaaatatgt ttcttattga atatttctat
     2821 caagtgaatc cacaatttaa aagtcacttt ggttttatat atacacacat ctgcagatat
     2881 aattttataa gaacacacaa atataatcct gtcattcgta ctggtttcca tgacatagta
     2941 tcttgttttc tttcattgtg gtacaatgca aagtagccac agattcctcc catcccaagt
     3001 agcgtctctt tgtctactac ttgactttga acttggccac gtgactttct ttggccaatg
     3061 gaaattagca aagagaatca ataagaagct tgagaagtgt gcaaagcctg ccttgaagct
     3121 taccctctct tgctgctctt tgcaaacctg aagaatctca aattgcccta ctcgggggtg
     3181 aggagccacc acatggagca gtggtgagcc agccttgctg aggcccctta gaccaagtag
     3241 cctgccaatt gtcagaattg ggagtgaggt tttccaagac ctctagcccc agctgagcca
     3301 gcctagccca gaagagccat accagttatt ccagctgatt tacagaattg tgagataaat
     3361 aaaatgatga tagttttaag caacatgagt tttggggtta gtttgttgta cagaaaatgc
     3421 taagtaatat ttgaaagtat atgtttgggg gagggggcat agtggaccaa aacgtgacaa
     3481 gtggcattgg ctttgggtct gagtggcacg tagaaactgg aaaaacagtg aggaaaactg
     3541 tttttcctca aataacaaag gttggatagt tggcaaccca tgttatttag tagggaaaga
     3601 tacagaaaaa cagtcatcac catactctgt gggaagatag agaatggacc aaacgaactg
     3661 gtggatctgg ctaaggagat ttgcagcaga atatgggaag tatcagtttg cttcttttag
     3721 ctgcatatga tacgatacag aaagagagaa atgaactaaa gaaataactg tttctttggc
     3781 aagcagaatt cagaagaaat atggaaaagc caaggattgc tgggttgaaa aataatgctt
     3841 tcacatcact agtctctcca gctatctaac tattcgcaag gtaaaaaatg gcctcagggt
     3901 aaagatcaaa tcatggttgt gtctgtaaga ctctttatta cagtgtgtga aatagttcag
     3961 ttggtgctta ggagaccatc tcagctaaac ttaagggctt ctaaaaatct tcatgacgtt
     4021 gtcccataga agcctgacat actactcaaa gtggagagag acctatctta aaaagaattg
     4081 ctgatgtggc atttggggaa aggagtagat ccaaaccaga ttcataggaa actcacaaag
     4141 tttttaatag agttttacta gtaaaactac ctccaggttg gacttccagg gactgaaaca
     4201 gttcaaaatg aaaagtggcc tctggattcc cctccctaac ttctatgaat aggatacaag
     4261 ctgagaaagt tactcagatg caaacacggt ccatttctta tggaaaatga agggcatctc
     4321 agagggaaga cccaagaaca atatattaaa atgagctggg gagccgttcc cagggagaac
     4381 tgtgccctaa tcaagaaacg tatctgcccc tggagccaag ggaaccgaca acatttgctc
     4441 tgtgggattt cagaatcgtt atggaacagt gactgatatg tgcctcatgg tcctcctctt
     4501 tttgaatggg agtgtctatt acagttatcc tgtacctatc ccaccattgt atatattggg
     4561 tgtatgttgg ggggcatgta acttgtcatt tagctcacag gtatctggat caagaaactg
     4621 aaaaactgta cccaaggaac ctcagccaca cctgaacctg atacagaaga cttgagattc
     4681 tggattggag cttgatgcca caattttgga tgagaaattt ggaggtcctg gaataggggt
     4741 gaacacattt tgcatggggt ggtaatgtga atactttgtg accagaagac acactgtgtt
     4801 aggtagaaaa atgctacaga tgtcttcatc cctgtatatg tgtccttctt cagtctttat
     4861 ttctctttgt gtttcagtta ggataatttc tattgatctg tcttcaaatt cactgatgtt
     4921 ttttctctca ccctggcttt gtcaagtcta ctgctgaacc cattgaaggc attcttcaac
     4981 tcagttatgt tttattttta tttgtaatat ttccatttga ttcttacaat tttcatatat
     5041 ctgctgaaat tccccatctt ttcatgcatg ttcatgtttt cccctttacc ctttgtctta
     5101 gtcagtttga gctgctataa taaagcacca tagacttggt ggcttataaa caacagaaat
     5161 ttattcctca cagttctgga gcctggaagt ctgagatcag aatctagcaa ggttaggtct
     5221 tggtgacggc cctcttcaag gttgcaaact gctcacttct tgcattttcc catgtctaca
     5281 gctagagaac tctttgggat cccttttata agggcaccaa tcccattcat gagttctcca
     5341 cccacattac ctaactacca cccaaaggct ccacctccta ataccatcac attgaggatt
     5401 aggattttaa catatgaatt ttggggggga tgcaatcatt cagcccataa taccctctaa
     5461 catattaatc atagttattt ttaactccct gtctgatagt tccaactact aggtcaactg
     5521 agtctaggtc tgttgttgtc ttctcttgct cttttgcatc taataatttt tggctgaatg
     5581 tcacagatgt tgtatgtagg acagtagaaa ctgaggtaaa tagtaattat tcctggaaac
     5641 agccatggtt gcccttttga taggccatta gcatggggag attgaatcca tctaatcagg
     5701 agttgggctg agtttgtgtt tctttgttgc cagtgttacc tttgctgtac catagactta
     5761 aaattcctct attgttatct tatgcttgag gtaggcactg gtttgcccag agaattttta
     5821 tttttcccag accacacttg cctttaggcc tgtaggcctt tcctgtgtgc ctgcatctca
     5881 gggagggtct ctctccatgt tgttgcctct atgttagtag tagacaactg ttattacttg
     5941 gttcttgctg acctggtgag ttggggggca ggggttgtct tgggccagcc tcagtttttg
     6001 tcaggccatg aatccctggg tcttgagggt gggatttttt agtgatcctg ccctcttcca
     6061 ctggtagaag gcctttaatg atctgggccc aggatgattt cctgcccttt tatcatgggt
     6121 ggaatttttt tttccatttc cctcactcta gtcacagtga atctttaact gtgtcctgag
     6181 ggcaacaggg tttgctgcac ttcttttagt ggcttaagga ttttgttctg taggggagta
     6241 gggtttcatt ggagctttgt gccatttcta tgttaacagc agcccccttg caggcctacc
     6301 ccatggaggt aggctttctc cagtcttctt ccttgtcccc gtgtttcttg agagcactca
     6361 gtggatgact atggagaaga gcctgcaagc agagaccaac tacccttagg tctacagctc
     6421 tcatgagtct cccgcactca gcctttagca attcattaaa aattcttgtt gaattcttac
     6481 tgcttgtata gtggcctcat cttccttcct gctgtaccac agatggccca ggagaggcac
     6541 ttgtctttta ttatatttca agctagttgg ttgctctgta atcttagctc tctgatgggt
     6601 tcgagaaaac ttatgttttt gcagattacc cagctttgtt cttgttataa agatgggagc
     6661 agtgttcttt ccagatgtct acatgctagg cagaaactag aagtctggac agtctccatg
     6721 gtctcctact atcagaatat gtgccctttt cagtgtgact ttgccacttc acccatcaag
     6781 aggtagaatc tatttcttca acccctgcaa ctgagcttgg ctattttgtt ggccaatggg
     6841 acattaacaa gtatgataca agcagaggct tgagaagtgc ctgcacaatg aggcttgccc
     6901 acttttgcag ctctttggaa tcctgaaccc atgtgtggaa aagcctgaac tgtgctgttg
     6961 gaaaatgaga gcgatcacat ggagcagtaa tggagcaaag accagccatc ccagttgaga
     7021 taccctacac caaccagatt ttcaactgct ggacatatga atgaagctat cctaggcatg
     7081 cagtcttggt caaggcaact ttggctggca gtctctgaga tgaccctgaa tgatccccac
     7141 ctcctggtat tctcactctt atataatccc ctcctcttga gtttggactg gaattagtga
     7201 cttggttcta gtgaatagaa tgaggcagag gtaatgggat gtcatgttca agattggtta
     7261 caaaaagact gtggcttcca ttttgggtgc ttgcttactc tctcagatgg ctcatcatag
     7321 gggaaacctg ctgctacatc atgagatagc cctgtggaaa ggtccacatg agtgaacttt
     7381 gaagcatatc ctcccccagt ttagccttta gatgaggacc acagccaaat agcttgactg
     7441 taagccagat agcttgactc atgagggacc ttcagccaga ggcatctttt gagccatacg
     7501 aattcctgac ccatagaaac tgcaagacaa taaatgttgt tttaagttgc taaattttag
     7561 ggtaatttgt tacacagtaa taggttaata atacactggc ccagattagg aaggttctgc
     7621 catccatccc agccatccca aacaactacc agaataatgg attaaaacgt taactgtttt
     7681 aagtcactaa gttttgggca gcatgataac aacccagcaa aaagctaact gatacattga
     7741 ttatttattg catttcttcc tccactattc ttctctaaca gatgaccaat actaataaac
     7801 tactgtgaac actttcatgt tttaatctct gctctgtgct cataatcata tatagacata
     7861 catacgttcc catgcttgta atcagaagtt atataagatt gtttcctcct ttgattttca
     7921 aaaatgggat cataacatac aaccatctct gcagcttgct ttattattat tcaacaatat
     7981 ttgttttgaa tggttgcatg atagtttatg gggtggatgt acaataatgt attaaactat
     8041 ttgcattgtt aaaatttatt cactcccatt ttcaaccctt ttttgtcact gggaacaatg
     8101 ctgctaaaaa tattaaaaga tagtttgcat agtggttagg tagataggct caggaaccca
     8161 tctgccaggg tttcaatcct ggctctacca atttactagt ttatgtgacc ttgggaaagt
     8221 tagttaacct ctgtcctgat ggttttcatc tataaaagat gtacacacta ccacctatca
     8281 tagatttgac taagaagcat atttctttcc tcgggctgct ataacaaagt accacaaatt
     8341 gggcagccta aaacagcaga aattgtctca ttgttcttga ggctggagat ccgaatcacg
     8401 gtgtcagcag ggtcatgctc cctctgaagg tgctagggaa ggaacggttc catgcctctc
     8461 tcctagcttt tgagagcttc aggtgttatt tggcttatag atgcattatt cctgtcagat
     8521 ggctgttttc tccctgtgtt tcttcacatc atgttccctc tgtgtgtctg gctctctttc
     8581 caaatttccc cttttataag gacactagtt atattggagt ggggttcact ttaatggccc
     8641 cattttaact taattacctc tgtactctat ttccaaataa aattgtattc tgaggttctg
     8701 gggattagga tttccacgta tcttttttgc aggtacacag ttcattaaca agaagttaat
     8761 gcatattgtg tagagctctt agaactatgc atggagagaa tttcttaatg ggtattagat
     8821 acacctcact tcctgagccc gcacaggtcc ccctacaact ctctgtgctt gggacactga
     8881 ggtgggattt gagagcttgt ttccggcatc ttagtgtcat ccagctatct aaagaaaatg
     8941 tagggagtaa caggaaaagc aggcctaaga ccaaagcttg tgctttgggt cgagaaggat
     9001 atgcctatag aagataatga gaaggagcag ccagagaggt aaaaacatac caggtgagca
     9061 aggggctcat agagaacagt gtttccaaca agtgttttaa tggaggactt gtccaaatta
     9121 gacatcaatt catatgagga tggaaaattg gttcttgatt ttatgacaca gaggttgttg
     9181 ttggctttga tgaatgctat tttggaagta aatttaaaca aagcaattga gcaaactcag
     9241 aggaatttct gaattcaggt ggtgttactt caccatgaag caatttttct catagaaaaa
     9301 tatcaagcca ttggactaga ttattctgtc gtttgggtta tactgagaaa taagagttgg
     9361 ctaaagtaga aattacatga gatttggaag gtcaaaggga aggagcaact attgctgtga
     9421 aagtctttga aattagagac agtgaaggac agatgcagag gtacccagca ggttccagtt
     9481 tttcctatct tccactctat atccagccct tctttccatc ttccagccct gctgaccaac
     9541 agtagcccca ggtctaccac cagatgcttg gctgcaggct cacaaaagct tctcatggac
     9601 ttctccacca gcttctcatg gcagtcccac atcagcagct agatgtgcct ggcttctcag
     9661 attttcctga aagctctgat ttatccaccc atgctaatgt ctcaaaaggg ctggtttagt
     9721 gatttcttta gtcttctaac tcccccttct aaaccttccc cagctacctc tataaattgt
     9781 gcatgcatcc cttattccat aatgctcata gttattatgc ttccctgatt gacatattta
     9841 tactttcttt tcctgagaat ttggtagatg ctgctcttct aaaattgagt gatgttatta
     9901 agaagtctta gacaaacttg ctctcttttt tcttgtatat aatgtgcctt tctgccatat
     9961 gattcttttt ttattcttga agttaaggat ctatggaagc atatgctttg gtcctgatct
    10021 ttgtgtatta attttacctg agttatagtg agccattcca atcattcatt tcaaggaagt
    10081 tttattttgc ttaacatttt ttctgatcca tttcttctct tcttcaggga catcaattat
    10141 gcatatgtaa gatgtctttg tcaccttcta cattcatctt ctaccaatca acatccattt
    10201 cacatcatta ttcttttcag ttttgtgtga ttgactctag ccttgtcttc agagacaatt
    10261 ctccttgaat ctcatgttct tcatgtttag acattaacaa gcaatttgct cagatttatt
    10321 tacattccag gatagtaaag atagagaatg tctccctccc tggagacttt cccagagaag
    10381 atttggttgc attccaggtt aataaagatt atatatatat atacccaaag aagaggatgg
    10441 acaataaaac aatataacat tatttccctc acatcttaat tatgtgtatt ttcaatcatg
    10501 tagaaatatt gaaaacacag tacaacctat ataacatcca tctagattta acaatttata
    10561 tgtaattttt cctgaaatac cagtggtaag ttatagatat aacattataa ccataaataa
    10621 ttgagcattc atctcctaaa aataaggaca ttctcccaca tacctggaat atcattatca
    10681 atctaattct atgatatatc cagtccattt ccaaatttct cccattgtcc ccaaaacata
    10741 ttttacagtt ttaatgaggt agaattagca tacagaaagt ggaacttgtt taaagtgtac
    10801 aatttgatga gttttgacgt gtgcaccttt ccaaccatca tgacaataca aataatgaac
    10861 atatcaatca ccccaaaaaa gtttccttat gcctctttgt cattcagccc cctttcccca
    10921 cattcttccc acatccacag gcaatcatgg atctgttttc tattgttata gattagtttg
    10981 cgtttcctac aattttatac acatggaata atactatagg tactcttgtt tggctccttc
    11041 catccagcat aataagtttg agattcattc atgttgttat atgcgtctat gttcattcct
    11101 ttttattgct aagtgttatt tcattatatg gacataccag aatttgttta tccattcatg
    11161 ttttgatgga aatttgtatt tccagctttt ggctattaca aataaaactg atgtgaacat
    11221 ttgtttacaa
//
