LOCUS       NM_021089               9110 bp    mRNA    linear   PRI 12-NOV-2024
DEFINITION  Homo sapiens zinc finger protein 8 (ZNF8), mRNA.
ACCESSION   NM_021089
VERSION     NM_021089.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9110)
  AUTHORS   Zhang,Y., Yang,Y., Hou,Y., Yan,W., Zhang,X., Huang,X., Song,Q.,
            He,F., Wang,J., Sun,A. and Tian,C.
  TITLE     ZNF8 promotes progression of gastrointestinal cancers via a
            p53-dependent mechanism
  JOURNAL   Cell Signal 123, 111354 (2024)
   PUBMED   39173856
  REMARK    GeneRIF: ZNF8 promotes progression of gastrointestinal cancers via
            a p53-dependent mechanism.
REFERENCE   2  (bases 1 to 9110)
  AUTHORS   Geng,W., An,J., Dong,K., Zhang,H., Zhang,X., Liu,Y., Xu,R., Liu,Y.,
            Huang,X., Song,H., Yan,W., Sun,A., He,F., Wang,J., Gao,H. and
            Tian,C.
  TITLE     ZNF8 Orchestrates with Smad3 to Promote Lung Metastasis by
            Recruiting SMYD3 in Breast Cancer
  JOURNAL   Adv Sci (Weinh) 11 (40), e2404904 (2024)
   PUBMED   39225541
  REMARK    GeneRIF: ZNF8 Orchestrates with Smad3 to Promote Lung Metastasis by
            Recruiting SMYD3 in Breast Cancer.
REFERENCE   3  (bases 1 to 9110)
  AUTHORS   Yang,H., Sun,W., Bi,T., Sun,J., Lu,Z., Li,J. and Wei,H.
  TITLE     ZNF8-miR-552-5p Axis Modulates ACSL4-Mediated Ferroptosis in
            Hepatocellular Carcinoma
  JOURNAL   DNA Cell Biol 42 (6), 336-347 (2023)
   PUBMED   37126948
  REMARK    GeneRIF: ZNF8-miR-552-5p Axis Modulates ACSL4-Mediated Ferroptosis
            in Hepatocellular Carcinoma.
REFERENCE   4  (bases 1 to 9110)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 9110)
  AUTHORS   Beausoleil,S.A., Villen,J., Gerber,S.A., Rush,J. and Gygi,S.P.
  TITLE     A probability-based approach for high-throughput protein
            phosphorylation analysis and site localization
  JOURNAL   Nat Biotechnol 24 (10), 1285-1292 (2006)
   PUBMED   16964243
REFERENCE   6  (bases 1 to 9110)
  AUTHORS   Jiao,K., Zhou,Y. and Hogan,B.L.
  TITLE     Identification of mZnf8, a mouse Kruppel-like transcriptional
            repressor, as a novel nuclear interaction partner of Smad1
  JOURNAL   Mol Cell Biol 22 (21), 7633-7644 (2002)
   PUBMED   12370310
REFERENCE   7  (bases 1 to 9110)
  AUTHORS   Lania,L., Donti,E., Pannuti,A., Pascucci,A., Pengue,G.,
            Feliciello,I., La Mantia,G., Lanfrancone,L. and Pelicci,P.G.
  TITLE     cDNA isolation, expression analysis, and chromosomal localization
            of two human zinc finger genes
  JOURNAL   Genomics 6 (2), 333-340 (1990)
   PUBMED   2106481
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK093110.1, AK225825.1 and AC020915.6.
            
            On Nov 23, 2018 this sequence version replaced NM_021089.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK225825.1, AK093110.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000621650.2/ ENSP00000477716.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1403              AK093110.1         4-1406
            1404-2189           AK225825.1         1403-2188
            2190-2207           AK093110.1         2193-2210
            2208-9110           AC020915.6         143223-150125
FEATURES             Location/Qualifiers
     source          1..9110
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..9110
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /note="zinc finger protein 8"
                     /db_xref="GeneID:7554"
                     /db_xref="HGNC:HGNC:13154"
                     /db_xref="MIM:194532"
     exon            1..193
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1855
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /note="zinc finger protein 272; zinc finger protein 8
                     (clone HF.18); zinc finger protein HF.18"
                     /codon_start=1
                     /product="zinc finger protein 8"
                     /protein_id="NP_066575.2"
                     /db_xref="CCDS:CCDS12974.1"
                     /db_xref="GeneID:7554"
                     /db_xref="HGNC:HGNC:13154"
                     /db_xref="MIM:194532"
                     /translation="MDPEDEGVAGVMSVGPPAARLQEPVTFRDVAVDFTQEEWGQLDP
                     TQRILYRDVMLETFGHLLSIGPELPKPEVISQLEQGTELWVAERGTTQGCHPAWEPRS
                     ESQASRKEEGLPEEEPSHVTGREGFPTDAPYPTTLGKDRECQSQSLALKEQNNLKQLE
                     FGLKEAPVQDQGYKTLRLRENCVLSSSPNPFPEISRGEYLYTYDSQITDSEHNSSLVS
                     QQTGSPGKQPGENSDCHRDSSQAIPITELTKSQVQDKPYKCTDCGKSFNHNAHLTVHK
                     RIHTGERPYMCKECGKAFSQNSSLVQHERIHTGDKPYKCAECGKSFCHSTHLTVHRRI
                     HTGEKPYECQDCGRAFNQNSSLGRHKRTHTGEKPYTCSVCGKSFSRTTCLFLHLRTHT
                     EERPYECNHCGKGFRHSSSLAQHQRKHAGEKPFECRQRLIFEQTPALTKHEWTEALGC
                     DPPLSQDERTHRSDRPFKCNQCGKCFIQSSHLIRHQITHTREEQPHGRSRRREQSSSR
                     NSHLVQHQHPNSRKSSAGGAKAGQPESRALALFDIQKIMQEKNPVHVIGVEEPSVGAS
                     MLFDIREST"
     exon            194..320
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /inference="alignment:Splign:2.1.0"
     exon            321..416
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /inference="alignment:Splign:2.1.0"
     exon            417..9110
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2165..2170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /note="hexamer: AATGAA"
     polyA_site      2191
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /note="major polyA site"
     regulatory      8340..8345
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /note="hexamer: ATTAAA"
     polyA_site      8358
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
     regulatory      8608..8613
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /note="hexamer: AGTAAA"
     polyA_site      8626
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
     regulatory      9092..9097
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
                     /note="hexamer: AATAAA"
     polyA_site      9110
                     /gene="ZNF8"
                     /gene_synonym="HF.18; Zfp128"
ORIGIN      
        1 gtagtcgccg cgtcgccggt gcggccgcca ttgtccggcg ttcggcgagt cgggtggtcc
       61 ctttggctgg agtgcctctc tggtctgggg atcacctcag gcgctgtcct tcactgggcg
      121 atccagcatg gaccccgagg acgaaggggt agcgggagtg atgtctgtgg ggccgccggc
      181 ggcccggctt caggaaccag tgaccttccg ggatgtggct gtggacttta cccaggagga
      241 atgggggcag ctggacccta cccagaggat cctctaccgt gacgtgatgc tggagacctt
      301 tggtcacctg ctctccatag gtcctgagct tccgaagcct gaagtcatct cccagctgga
      361 gcaagggacc gagctatggg tggctgagag aggaaccacc cagggctgcc atccagcctg
      421 ggagcctcga tctgaaagcc aagcatcacg caaggaagag ggcctgcctg aagaggagcc
      481 atcccatgtc acgggaaggg aaggattccc gacagatgct ccttatccca ccacgttagg
      541 gaaagacagg gagtgtcaga gccagagtct ggcactcaag gagcagaata acttgaagca
      601 gttggaattt ggcctcaagg aagcaccagt tcaagatcaa ggctacaaaa ctctcagact
      661 cagggaaaac tgcgtcctga gttcaagccc aaatccattc ccagagatct ctagagggga
      721 gtatttgtat acttacgact cacagattac agactcagaa cataactcca gcttagtcag
      781 tcagcagaca ggctccccag gaaaacagcc cggtgaaaac agtgactgtc acagagattc
      841 cagtcaggcc attccaatta cggaactcac aaaaagccag gtgcaggaca aaccctacaa
      901 atgtactgac tgtgggaagt cgtttaacca taacgcacac ctcaccgtgc acaagaggat
      961 tcatacggga gaaagacctt atatgtgcaa ggagtgtggg aaagccttca gccagaactc
     1021 ctccctcgtc cagcatgagc gcatccacac tggagacaag ccctacaagt gtgccgaatg
     1081 tgggaagtct ttctgccata gtacacacct taccgtccat cggaggattc acactgggga
     1141 gaagccctat gagtgtcagg actgtgggag ggccttcaac cagaactcct ccctggggcg
     1201 gcacaagagg acacacactg gggagaagcc atacacctgc agtgtgtgtg ggaaatcctt
     1261 ctctcggacc acttgccttt tcctgcacct gagaactcac accgaggaga ggccctacga
     1321 gtgtaaccac tgcgggaagg gcttcaggca cagctcatcc ctggcccagc accagcggaa
     1381 gcacgcgggg gagaagccct ttgagtgccg ccagaggctg atctttgagc agacgccagc
     1441 tctcacaaag catgaatgga cagaagccct gggctgtgac ccacctttga gtcaagatga
     1501 gaggactcac cgaagcgaca gacccttcaa atgtaatcag tgtgggaagt gtttcattca
     1561 gagctctcac ctcatccggc accagataac tcacaccaga gaggagcagc cccatgggcg
     1621 aagccggcgg cgtgaacaat cctcgagcag gaactcacac ctggttcagc atcaacaccc
     1681 gaactccaga aagagctctg caggcggagc aaaggcaggg cagccggaaa gcagagccct
     1741 ggctttgttt gacatccaaa aaatcatgca agagaaaaac cctgtgcacg ttattggggt
     1801 ggaagagcct tctgtgggtg cttccatgtt atttgacatc agagaatcca cataggagag
     1861 aaactttgct gatgactttt aaccacaagt aaaaaatgtg gtaagtccac atagtgtact
     1921 catggaagga ggggctgggg gtagaaatgt catgggtgac ttctgacttt ctaaggaaat
     1981 gatgcttccc aagcacccga ggttggttgg tcccaaatct atcaaactca gtgccctctt
     2041 tagcgacata ttttgtgaca ttccttccat tacaccacag tgagttcaca ggtaatataa
     2101 cctacccacc tgtgtaatgt caaaaaaaat caatatgcgg ccccattttg taaaggatca
     2161 ttaaaatgaa agtaatttat ggtagagtaa attgtagagt aacgtgtact gacttggtgc
     2221 agtatttctc cttgtcactg tgggcccaat tttgccagga gacctagggc aatagcctgt
     2281 tgcttgtgga ctggtagagg gtatgatgtt gaccatggca atactgtgag gggccttccc
     2341 atgtggaacg tgaccttcca aagtagtgac taactcttgg aaaagttttt aacaacataa
     2401 tatgctattg catttctggg aaattctggg taaattccaa gcatgcagca attagtttgt
     2461 gcttatgtgt gaagtccagt taggttctca gttcataccc tgaaaactgc ttattccaca
     2521 tctgttgatg tggtccactg ggggcagttc tgttcctcac catcttggca gcatgcatgg
     2581 ctcctgccca catttcaacc acacccccaa cccaattacg tgaccagccc ccacgaaatt
     2641 tcacagcatt ccgtgcaggg gagtgtcaca gctcctcttg aaaaacatct ggtgttgcta
     2701 tgagccagaa gttctttttt ttgttttttg tctgagatgg agtctcgctc cgtcacccag
     2761 gctggagtgc aatggcgcag tctgctcacc acaacctccg cctcccaggt taaagcaatt
     2821 ctcctgcctt agtcccccga gtagctggga ttacacgcac ctgccaccac gcccagctaa
     2881 tttttgtatt tttggtagaa atggggtgtt ggccaggctg atctcaaact cctgacctcg
     2941 tgatccaccc acctcggcct cccaaagtgc tgggtttaca ggcatgagcc actatgccca
     3001 gctgagccag aggttcttaa ctggtggtgc ttttgcctcc agggcacatt tggtgacatc
     3061 tagggacatt tttggttgct gtgcctggag gaagggtgcc gccgtcatgt agtgggtaga
     3121 ggccagggac gctgctcaac atcctttagt gcccgggaca gctcctcaac aaaggattct
     3181 ctagctcaaa tgtcaatagt gccaaggtgg agaagccacc tgggtataaa cccagcccag
     3241 aaatgtagct gacattttta aaacttgcag ccagctgtgg tggctcacgc ttgtgatccc
     3301 agcactgtgg gaggctgagg agggcggatc ctttgaggtc aggagtttga gactagcctg
     3361 ggcccatggc gaaaccccat ctctactaaa aatacacaaa ttagccaagt gtggtgacat
     3421 gcgcctgtaa ttctagctac ctgggggagg ctgaggcacg agaatcgctt gaacctggga
     3481 ggcagaggtt tcagtgaacc gagattgcac cactgcactc cagcctgggt gacagagcaa
     3541 gactctgtct cagaaaaaaa aaagaaaaga aaaaaaacct tcaaattgat taatcagggc
     3601 tggactagac tagaaatcat ataagcttga ttttaacaga tggcatcatt agctagttta
     3661 tacatgatgt actttttagt acatccttta cggttttgca gcattcataa ttgatgtgaa
     3721 ataaggaaga taatcctttt tttttttttg agacagagtc tcactctttt gcccaggctg
     3781 gagtcagtgt tgtaatcact gctcacttgg cagcctcgac ctcctgggct caagtgatcc
     3841 tcccacccca gcctcccaag tagctgggac cacaggcatg tgccaccatt cctgattttt
     3901 tttatttttt gcagagacag ggtctcactg tgttgcctag gctggtctcg aaccttggcg
     3961 tcccaaagtg ttgagattat aggcatgagc cactgtgccc agccacttat ttttctgagt
     4021 aacctttaag gatgtattgt ggacattttc aaacatgagt catatatttt tgctggtact
     4081 cccatctacc tccccaccat tctccttccc tggatatata tataaccatg tttgtccact
     4141 gggacaaaac cattttcaca atcatactaa gctgtcattt cacatttttg ctgtgcactg
     4201 atagtgtgaa agcaatggca ggtaaaactg ctgagcctga gttcaaagca gggcagtagc
     4261 cctgaggttg gttgttcata ttcttctcca ctgggaaatg cagtaaagaa aaagaaaagc
     4321 taatttcact taatttcttt tcttttcttt tttttttttt tcttttgaga cggagtctcg
     4381 ctctgtcgcc caggctggag tgcaatggcg tgatctcggc tcactgcaac ctccacctcc
     4441 acggttcacg ccattctcct gcctcagcct cccgagtagc tgggactaca ggtgtgcgcc
     4501 atcttgccca gctacttttt tgtattttta gtagagatgg ggtttcacca tgttagacag
     4561 gatggtgtcg atcttctgac ctcataatcc gcccacctcg gcctcccaaa gtgctgggat
     4621 tacaggcatg agccactgcg cctggccctc tttttctttt tgagatggag tattgctctg
     4681 tcgcccaggc tggagtgcag tggcacaatc ttggctcact gcaacctccg cctcccgggt
     4741 tcaagcagtt ctcatgcttc agccctctaa gtagctggga tgacaggtgt gcgctaccac
     4801 acccggctaa tttttgtatt tttagtagag atggggtttt accatgttgg ccaggctggt
     4861 ctcaaactca tgacctcaag taatctgccc gcctcagtct cccaaaatgc tggcattaca
     4921 ggcatgagcc accgtgcctg gcctactttc actgaatttc tgtgatgaaa cgggaaaaat
     4981 taattttgtt aaatctcaag tagaactata ttgtcattat cacatctaaa cagatatcat
     5041 caaataccta gtgttcagat gttctgggtt gcctcataaa ttttgttttc tatttgtttc
     5101 atagtaatca taatctaaac aagatccaca cagtgcattt ggttggaatt tttctttttt
     5161 ctttttcttt tttttttttg tgatggagac ttgctctgtc acgtggttca ctgcaacctc
     5221 ccaggttcaa gcaattctcc tgcctcagcc gcccctgtag ctgggactgc aggcatgcac
     5281 caccacactc agcagatttc ttaattgttt gtagagatgg ggttttacta cattgcctag
     5341 gccagtttca aactgggctc aagcgatcct cccaccttgg ccatccaaag tgctaggatt
     5401 acaggtgtga gccaatgcac cctgccaaac agcaattttt tttttttttg agacagagtc
     5461 tcgctgtgtc acccaggctg gagtgcagtg gtgcgatctc ggctcactgc aagctccgcc
     5521 tcccaggttc atgccattct cctgcctcag cctcccgagt agctgggact acaggcgccc
     5581 gccaccacgc ccggcaaatt ttttgcgttt ttagtagaga cggggtttca ccctgttagc
     5641 caggatggtc tcaatctcct gacctcgtga tccacctgcc tcggcctccc aaagtgctgg
     5701 ggttacagga gtgagccacc gcgcctggcc ccaaaacagc aatttgaata accatgttgg
     5761 aatggttgag cattggaacg cattagcatc agaacttccc gtgtcaggcc aggcgcggtg
     5821 gctcacgcct gtaatcccag cactttcgga ggccgagatg ggcagatcac gaggtcagga
     5881 gatcgagacc agcctggcta acacggtgaa accctgtctc tactaaaaat acaaaaaatt
     5941 agcctggcgt ggtggcgggc gcctgtagtc ccagctactc gggaggctga ggcgggagaa
     6001 tggcgtgaac ctgggaggca gagcttgcag tgagctgaga tagtgcctct gcactccagc
     6061 ctgggtgaca gagctagact ccatctcgaa aaaaataaaa gaacttcccg tgtccgtttt
     6121 tgctttttgg atgctgggag tgtcacaact cagctatcca atcaaggcag agctggcctc
     6181 caggatgcca gagccagagc tttgtggttc atctctagag gttcaacagg accctgtgga
     6241 tggcccaagt tcgtttctct gcacttacct cttcggggtt gtcctcaaaa cgttgccgtg
     6301 tcagctctca cttttcacag caactctggc ctcctacctt ggactgcgcc acttctgtct
     6361 ccttagataa cctccattcg catagctaaa tgctgcaccc tccgacactg ccacaataat
     6421 agttctgtga gttagtacca ttttatagat aggcaaaatt tggcacagga caaaagttag
     6481 tggtaactag aacaaaagta accagcccaa gctaggaagt ggtggagtta gaatttgatg
     6541 tcagcaccca gctgaccatg gcttaaacag atgaggcttt gttcaaaggc tgtcttttca
     6601 gtggctcagc tgtgtcacag tcgatgtttt ctgcaatctc tcaacctttc cattgtggtc
     6661 atgaggagac tcctatggct ccagccattg catccacagt gaagactgaa agaaggggga
     6721 atgggcaggc caacacttac cgctgatggt gtttaaagga aaaacattcc cagaagcctg
     6781 cagcacatgc cccccttagt ctcactggcc acagatgggt cagggggcca cccctaataa
     6841 caacggggct tagaaacctc gtatttacct ttctaacctc tgtggtggag acaggtggga
     6901 gagaaaagtc ctgggaagtg gatgatggag gcagctagcc gtagctgctg cttttctctt
     6961 caagctcttg ggagaattgc ttgtgctccc tattcccttg gtggatgatg gaggcagcta
     7021 gccgtatctg ctgcttttct ccttcaagct cttgggagaa tcgcttgtgc tccctattcc
     7081 cttggtggca gctcacacct cagacctgct gtccgccccc actgcttcac agaacccact
     7141 gcaaccactg tccaaggtac tacctctggt gtcgtctctc ttcatcccca ggactgtgaa
     7201 gcctgctaac ctctttgcag agctccatct ccttgcattg tggggttcct tctaactctt
     7261 cagggacttc tcaacctccc gtcacccttc ctaaatgctg gggtcctaga gtccaccttg
     7321 tgctccacgc cctccccagg tgtcatctac atccctagct ttgtgctgct caccaccaaa
     7381 tcagtctggt gcttctgaga tttgggcttc agacccaaac aactgctgtg tgctactggg
     7441 caactccccg aggtgtgccg aaagctcccc aaacccagcc taccccaaac aaaactcatt
     7501 ttccacccag actagtctct gcttccctga tccctttcct ggaggctgtt tccacttgcc
     7561 atcccatcat ggaagccaga aaaccagtct tcttgacctc tccccttccc cactccatgg
     7621 agttagaggt cctgttgatt ttgccatgta aacatttcgg atttgcttac ttcatcccca
     7681 ctgccaccaa cagtgcagga tggccctaag aggagaagta atgtgctacc aagtggccca
     7741 gccagagtgt gaaccaaaca gtctggtacc aaaaccctat tctggatcat tcctcctttc
     7801 tgctccacca gcagtttggg gcacaggctt gggaatccag acaggaaagc tcctcccctc
     7861 tgaagcagtg ggaccaaaaa tgacagcatg gttctagaca gctctggaag tcaggcctgt
     7921 gattgcctca ttccctccac cttggccccc aaaatggcca gtcctgaagg ggtcacagtt
     7981 gatacttctc tgagggggca tggggttggc tgaggttata gcagccccac agggtggtaa
     8041 gctgggatga agcaatcaac tggaactcaa caagccttga gttctcaaag ggggtgtggg
     8101 aaggttctta tacatcttct atgaagggca gtttatcagt cactaaatta caaatacata
     8161 aaccctttgt ctcaccaaac ctgctgggaa tgaatcctac atatatattt atatgtgtgc
     8221 aggctacatg gttttcatta tgctattgat tttaaaagta aaaatttgga aagaacctcc
     8281 atgtccacca tggggaactg gctaagtcat ttatggtgga atggtgatca taaaaattca
     8341 ttaaaaatga agactctata tacagcttga atattcctta tcgaaatgct tgggaccaga
     8401 agtgtttcag atctttgcat attttctgtt tctcatttca gttcacattt tctaagcatg
     8461 atattcctac tgatttcctt gtagatattt tgaaacagat aagaaactcc tccgtggaaa
     8521 ttactgttaa ctagggaaaa gacatgtttt tttctgttca taaaagtaat gcgagttctt
     8581 tgtagcaaaa cttggaaaat gcataaaagt aaaaaaaaaa tgaaaacttg tgtaaaattc
     8641 ctcatacttt agccatccat agatggtcct taccattagg attttactaa ttttccttgc
     8701 agctttttct taaaatatac acgtgtgtct acacatacat agtgtacact aaattttaca
     8761 tacacacaga ggaatatata tgtgtatagt tatcttgtgt ttagaaattt ggaatccctt
     8821 ctagttgtct tgtaacatgt gcttactcta ttttgaggat tttctctatg aatttcatgt
     8881 agctctttaa attaactttc aggaggattg taacaatgtg ctctccaccc agtattttac
     8941 cagccttgag ttttctcaaa gggggcattg gaggggttct tatacattta cagtgggaat
     9001 gtgaattgat acaacttctg tggagggcag tttatcagcc actatctaaa ttacacatac
     9061 ataaaccctt tgtctaagca aacttgctgg gaataaatcc tacacatata
//
