LOCUS       NM_153358               6465 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens zinc finger protein 791 (ZNF791), mRNA.
ACCESSION   NM_153358
VERSION     NM_153358.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6465)
  AUTHORS   Xin,H., Li,C., Cai,T., Cao,J. and Wang,M.
  TITLE     LncRNA KCNQ1OT1 contributes to hydrogen peroxide-induced apoptosis,
            inflammation, and oxidative stress of cardiomyocytes via
            miR-130a-3p/ZNF791 axis
  JOURNAL   Cell Biol Int 46 (12), 2018-2027 (2022)
   PUBMED   35989482
  REMARK    GeneRIF: LncRNA KCNQ1OT1 contributes to hydrogen peroxide-induced
            apoptosis, inflammation, and oxidative stress of cardiomyocytes via
            miR-130a-3p/ZNF791 axis.
REFERENCE   2  (bases 1 to 6465)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC329382.1, AK074877.1, BC106937.1, AK307775.1, BP319293.1 and
            AC010422.7.
            
            On May 17, 2019 this sequence version replaced NM_153358.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.113788.1,
                                           SRR1803616.196586.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000343325.9/ ENSP00000342974.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                DC329382.1         3-21
            20-690              AK074877.1         1-671
            691-1983            BC106937.1         627-1919
            1984-2067           AK074877.1         1965-2048
            2068-2278           AK307775.1         2010-2220
            2279-2360           AK074877.1         2260-2341
            2361-2369           BP319293.1         487-495
            2370-2454           AK074877.1         2351-2435
            2455-2456           BP319293.1         582-583
            2457-2493           AK074877.1         2440-2476
            2494-6465           AC010422.7         52258-56229         c
FEATURES             Location/Qualifiers
     source          1..6465
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.13"
     gene            1..6465
                     /gene="ZNF791"
                     /note="zinc finger protein 791"
                     /db_xref="GeneID:163049"
                     /db_xref="HGNC:HGNC:26895"
     exon            1..163
                     /gene="ZNF791"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..1891
                     /gene="ZNF791"
                     /codon_start=1
                     /product="zinc finger protein 791"
                     /protein_id="NP_699189.2"
                     /db_xref="CCDS:CCDS12273.1"
                     /db_xref="GeneID:163049"
                     /db_xref="HGNC:HGNC:26895"
                     /translation="MDSVAFEDVSVSFSQEEWALLAPSQKKLYRDVMQETFKNLASIG
                     EKWEDPNVEDQHKNQGRNLRSHTGERLCEGKEGSQCAENFSPNLSVTKKTAGVKPYEC
                     TICGKAFMRLSSLTRHMRSHTGYELFEKPYKCKECEKAFSYLKSFQRHERSHTGEKPY
                     KCKQCGKTFIYHQPFQRHERTHIGEKPYECKQCGKALSCSSSLRVHERIHTGEKPYEC
                     KQCGKAFSCSSSIRVHERTHTGEKPYACKECGKAFISHTSVLTHMITHNGDRPYKCKE
                     CGKAFIFPSFLRVHERIHTGEKPYKCKQCGKAFRCSTSIQIHERIHTGEKPYKCKECG
                     KSFSARPAFRVHVRVHTGEKPYKCKECGKAFSRISYFRIHERTHTGEKPYECKKCGKT
                     FNYPLDLKIHKRNHTGEKPYECKECAKTFISLENFRRHMITHTGDGPYKCRDCGKVFI
                     FPSALRTHERTHTGEKPYECKQCGKAFSCSSYIRIHKRTHTGEKPYECKECGKAFIYP
                     TSFQGHMRMHTGEKPYKCKECGKAFSLHSSFQRHTRIHNYEKPLECKQCGKAFSVSTS
                     LKKHMRMHNR"
     exon            164..290
                     /gene="ZNF791"
                     /inference="alignment:Splign:2.1.0"
     exon            291..351
                     /gene="ZNF791"
                     /inference="alignment:Splign:2.1.0"
     exon            352..6465
                     /gene="ZNF791"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4530..4535
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF791"
                     /note="hexamer: ATTAAA"
     polyA_site      4552
                     /gene="ZNF791"
                     /note="major polyA site"
     regulatory      4996..5001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF791"
                     /note="hexamer: AATAAA"
     polyA_site      5019
                     /gene="ZNF791"
     regulatory      5731..5736
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF791"
                     /note="hexamer: AATAAA"
     regulatory      5739..5744
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF791"
                     /note="hexamer: AATAAA"
     regulatory      5744..5749
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF791"
                     /note="hexamer: AATGAA"
     polyA_site      5749
                     /gene="ZNF791"
     polyA_site      5758
                     /gene="ZNF791"
     polyA_site      5761
                     /gene="ZNF791"
ORIGIN      
        1 aaatgcgtgc tacgtcactg tgcgatcggg ttgtgcttag cttggggtct cctggcccct
       61 tgacgcgtca ggttgctgta cccctgcatc ggatgcgctg taccctgcgc tggctccgtg
      121 aaccttaggg acaacaccgg gacacccgcg aggccggaaa atggactcag tggcttttga
      181 ggatgtgtct gtgagcttca gccaggagga gtgggctctg ctggctcctt cacagaagaa
      241 actctacaga gatgtgatgc aggaaacatt caagaacctg gcatctatag gggaaaaatg
      301 ggaagacccg aatgttgaag atcaacacaa aaaccaagga cgaaatctaa gaagccatac
      361 gggagagaga ctctgtgaag gtaaagaagg tagtcaatgt gcagaaaact tcagtcccaa
      421 tctcagtgtg acgaagaaga ctgccggagt aaaaccatat gagtgtacta tctgtggaaa
      481 agccttcatg cgtctctcat cccttactag acacatgagg tctcacactg gatacgagct
      541 atttgagaag ccatataaat gtaaggagtg tgagaaagcc tttagttatc tcaaatcctt
      601 tcaaagacat gaaaggagtc acactggaga aaaaccctat aaatgtaaac aatgtggaaa
      661 aaccttcata tatcaccagc cctttcaaag acatgagcgg actcacattg gagaaaaacc
      721 ctatgaatgt aagcaatgtg gaaaagctct tagttgttcc agttcgcttc gagttcatga
      781 aaggattcac actggagaaa agccctatga atgtaaacaa tgtgggaaag ccttcagttg
      841 ttccagttct attcgagtac acgaaagaac tcacactgga gagaaaccct atgcatgtaa
      901 ggaatgtggg aaagccttca tttcccacac aagtgttcta acacacatga taacacacaa
      961 cggagataga ccttataaat gcaaagaatg tggaaaggca ttcatttttc ccagtttttt
     1021 acgagtacat gaaagaattc acactggaga gaaaccctat aaatgtaaac aatgtggtaa
     1081 agccttcaga tgttccacct ccattcaaat tcatgaaaga attcatactg gagagaagcc
     1141 ctataaatgt aaagaatgtg ggaaatcttt cagtgcacgc ccagcctttc gagtacacgt
     1201 gagagtgcat actggagaga aaccctataa gtgtaaagaa tgtgggaaag cctttagtag
     1261 aatcagttac tttcgaatac atgaaaggac tcacactgga gagaaaccct acgaatgtaa
     1321 aaaatgtggg aaaactttca attatcctct agatttgaaa atccacaaga gaaatcacac
     1381 tggagaaaaa ccctatgagt gtaaggaatg tgcaaaaacc ttcatttctc ttgagaactt
     1441 tcgaagacac atgatcaccc acactggaga cggaccttat aaatgtaggg actgtgggaa
     1501 ggtgttcatt tttcctagtg cgttacgaac acatgaaaga actcacactg gagagaaacc
     1561 ctatgaatgt aaacaatgtg gaaaagcctt tagttgttct agttacattc ggatacataa
     1621 aagaactcac actggggaga aaccttatga atgtaaggaa tgcgggaagg cctttattta
     1681 tcccacaagc tttcaaggac acatgagaat gcatactgga gagaaaccct ataaatgtaa
     1741 agaatgtggg aaggccttta gtcttcacag ttcctttcaa agacatacaa gaattcacaa
     1801 ttatgagaaa cctcttgaat gtaagcaatg tggaaaagcc ttcagtgtgt ccacatcctt
     1861 aaaaaaacat atgagaatgc acaatcgata gaaactctat aaatgtgaga aataggagaa
     1921 agttttcaat tctaacagat gctttcaaag ttgtgaaaat tcccactgaa gagagaaatc
     1981 ctgtcaatgt aagtaatata gaaagcgaga tacaagatga ttcatgtata gtcaggtacc
     2041 acataatcat gtttcagtca gcaatggacc atataggttg gtagccccat aagattatat
     2101 aacacctaaa acatttctat caaccgcaat ttagtagcag tagtaacacc atagtgcagc
     2161 acattattta agtgtttatg gtgctggtgt aaacgtgctg cactttcagt tgtataaaag
     2221 tacaagacag cggccgggga cggtggctca cgcctgtaat cccagcactt tgggaggcca
     2281 aggcgggcgg atcacgaggc caggagatca agaccatcct ggctaacacg gtaaaacccc
     2341 atctctacta aaaatacaaa caattagccg ggcgtggtgg tgggcgcctg tagtcccagc
     2401 tacttgggag gctgaggcag gagaatggca taaacccagg aggccgagct gacagtgagc
     2461 tgagatccgg ccaacagagc gagactctgt ctcaaaaaaa aaaaaaaaaa aaaagtacaa
     2521 cacagctggg catggtcaca cctgtgatcc caacactggg agactaaggc agtaggattg
     2581 cttgatgcca ggactactct ggtcaaccta gtgagaccct gtctctacaa aaaataaaaa
     2641 cattttctaa gtgtggtagc acaccctgta gtcccatcta catgggaggc tgaggcagga
     2701 ggattgcctg agcccaggag ttcaaggcta cagtgaacca agatcacgtg atggcagtcc
     2761 agcatgggtg acagtgagac tgtatcaaaa aaaaaaaaaa aaaattggct gggcacagtg
     2821 gctcatacct gtaatcccag cactttggga ggctgaggtg ggagaatcag ttgaggtcag
     2881 gagttcaaga ccagcctggt caacatgatg aaaccctgtc tccattagaa atacgaaaat
     2941 tagctgggcg ttctggtgtg cctgtagtcc cagctacttg ggaggccaaa gcaggagaat
     3001 cgcttgaacc cgggaggtgg agattgcagt gagctgagat ctaccactac actccagcct
     3061 gggtgacaga gcgagactcc gtctcgaaaa aaaaaaaatt acagcacaga tgtgcaatat
     3121 atacttgata ataaatggct aagttactgg tttatatatt tacaatcctg ttttagaatg
     3181 tattcctgtg tttttttaac agtaagacag tctcaggcag gtccttaagg agatattccc
     3241 ggaaaaactt tgttatgata ggcgatgacg gctccatgtg caggactgcc cctgaacgta
     3301 ttctggcggg acaaaacatg gaggcagaag acaatgatat tgatgatcct caccccgtgt
     3361 agtcctacac taatgtgtgt ttgtgtctta gttagtcttt aacaaaaata gtttaaaaaa
     3421 atttaataga aaaagcttat agaatatgga cataaaatat ttttgtacag ctgtacaatg
     3481 tgttttaagc taaattatta caaagttttt aaaaataagt ttataaagaa aataatgtac
     3541 agtaagttaa ggtttattca ttattgagga aaaaatgttt ttatgaatgt agtgtagtcc
     3601 aagtgtacag tgtttataaa ttctccatta gtgtacagta acatcctggg ccttcgcatt
     3661 cactcaccac tcaactgact cacccagagc aacttctagt cctgcaagct atgttcatgg
     3721 agtgtcctat gcaggtgcat ccttttttat cttttatact gcatgtttac tctgtgtatt
     3781 ttctgtgttt agactcataa atacttaaca ttttgttaca atttcctaca gtgttcagta
     3841 caacaacatg ttgtatggtt tatagcctag tagcaataga ctgtaccata tagtctagat
     3901 gtgttgtagc tataccatct agatttgtgt aagttcactt tgtgatgttt gtaccatgag
     3961 gaaatcacct acaacacgtt tctcagaaca tatacccatg attaagcaat ctctgcctgt
     4021 aaaatgctcc agaaaattca caccatgata taaattcatc acacacgata taaaagttaa
     4081 ggcaaggcat ggtggctcat gcctgtaatc ccagcacttt gggaggccaa ggcaggcaga
     4141 tcacctgagg tcaggagttc gagaccagcc tggccaagac ggtgaaaccc catctctact
     4201 aaaaatacaa aaattacctg agcgtggtgg catgcacctg taattccagc tacttgggag
     4261 gctgaagcag gagaatcatt tgaacctggg aggtggaggc tgcagtgagc tgagattgtg
     4321 ccactacact ccagcctggg caacagagca agactccatc ccacacacca aaaaaaagtt
     4381 aaaaattttt tatcactggc tcattcttca agtacatctc tggactatga attgtaactt
     4441 aactactttt ccaagaagtc ttggaagtga gataattctg taagtactct ttaagcagtg
     4501 gtcaaaagtt taaaaggttg tgttttctca ttaaatcagt tagtaaaact tttctctttc
     4561 tcttgatgtc ttgattcatg agtaaactga agtgtatttt ttttttttcg agacggagtc
     4621 ttgctctgtt gcccaggctg gagttcagcg gtgtgatctc ggctcactgc aagctccgcc
     4681 tcccgggtcc acgccattct cctgcctcag cctccccagt agctgggact gcaggcgccc
     4741 gccaccatgc ccagctaatt ttttttgtat ttttagtaga gatggggttt caccgtgtta
     4801 agccaggatg gtctcaatct cctgacctcg tgattcgacc gcctcagcct cccaaagtgc
     4861 tgggattaca agcttgagcc accgcacccg gcctgaagtg tatttttttt ttcttttaaa
     4921 gaccagtgtt agtagaagtg tatttttaat atacaattag ttttaatttg tgtatagttt
     4981 ttcagttgtt ctctgaataa agagattgtt gaatactgac acactgtaac taggattttt
     5041 cctactggcc tcatgtggaa ggtggtgcat atattaccca ttatatattt atttcacctt
     5101 ttccgaaaaa ctgcttttta aatttcttgg ccagacacgg tggctcactc ctttgtaatt
     5161 ccagcacttt gggaaaccaa ggcaagcaga tcacttgagg tcaggagttc gagaccaacc
     5221 tggccaacat ggtgaaatcc catctctact aaaaatacaa aaattagctg ggcatgttgg
     5281 agggcacctg taatctcagc tacttgggag gctgaggcag gagaaatgct tgaacctgga
     5341 agtcagaggt tgcagtgagc caagatcaca ccactgcact ccagcctgga caacagaacg
     5401 agactccata tcaaaaaaat taaattaaaa tataataaat ttcttgccgg gcgcagtggc
     5461 tcacacctgt aatcccagca ctttgggagg ccgaggtggg cggatcacga agtcaggaga
     5521 ttgagaccat cctggctaat acagtgaaac cccgtctcta ctataaatac aaaaaattag
     5581 ctgggcatgg tggcgggcgt ctgtagtccc agctactcag gagtctgagg caggagaatg
     5641 gtgtgaaccc gggaggcgga gcttgcagtg agccgagatc gtgccactgc aatccagcct
     5701 gggcagcaga acgagactcc atctcaaata aataaataaa taaaatgaat ttcagctaga
     5761 agagccttat tccattttcc tttttattaa acatctggca taagttggta agtatgtgaa
     5821 gtttatcata tattcttatg cgaattatta ttttcgcctt ttttttataa ttctgtctgg
     5881 gatttgaata gtagagtttg aattcaggaa ggacacctgt gataggacaa taaaatctag
     5941 agctggacgt ggccctcctg ctacctgtcg acacaggtaa atttcctaga atctgttccc
     6001 tttatagatc catgttgaaa ttcacttata gcctcacttg catgagattt gccaggcaga
     6061 agtgaagaag acattagtca ggtattggaa ccccaccata cagggagaca gcctgcttcc
     6121 tgctcatttt cctggttatt ttctctgcca atcaaaagta tcctgaaaac accctgagct
     6181 gcttgacttc cattctcaaa gagatgtgtt ggtttccaca gttgtctcca caagctccgc
     6241 atcaaagatc cacgtacagt ttggattttc cttctagcct tcatgtgtgg cccaagcatc
     6301 tatttcagac tgtcatggtt ggcattgttc tctgaggttc tgtcttccct ttgtgtttct
     6361 atgagcttta atttgtatgg ttcttgttct gttaatgcca ctagggacta tgtattcctg
     6421 attccaccat gacagctaca gtaaaacagt aaaaaaaaaa aaaaa
//
