LOCUS       NM_007135               2078 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens zinc finger protein 79 (ZNF79), transcript variant 1,
            mRNA.
ACCESSION   NM_007135
VERSION     NM_007135.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2078)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2078)
  AUTHORS   Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Association of genetic variants with hemorrhagic stroke in Japanese
            individuals
  JOURNAL   Int J Mol Med 25 (4), 649-656 (2010)
   PUBMED   20198315
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 2078)
  AUTHORS   Oguri,M., Kato,K., Yokoi,K., Yoshida,T., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Assessment of a polymorphism of SDK1 with hypertension in Japanese
            Individuals
  JOURNAL   Am J Hypertens 23 (1), 70-77 (2010)
   PUBMED   19851296
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 2078)
  AUTHORS   Williams,A.J., Blacklow,S.C. and Collins,T.
  TITLE     The zinc finger-associated SCAN box is a conserved oligomerization
            domain
  JOURNAL   Mol Cell Biol 19 (12), 8526-8535 (1999)
   PUBMED   10567577
REFERENCE   5  (bases 1 to 2078)
  AUTHORS   Rousseau-Merck,M.F., Hillion,J., Jonveaux,P., Couillin,P.,
            Seite,P., Thiesen,H.J. and Berger,R.
  TITLE     Chromosomal localization of 9 KOX zinc finger genes: physical
            linkages suggest clustering of KOX genes on chromosomes 12, 16, and
            19
  JOURNAL   Hum Genet 92 (6), 583-587 (1993)
   PUBMED   8262519
REFERENCE   6  (bases 1 to 2078)
  AUTHORS   Huebner,K., Druck,T., LaForgia,S., Lasota,J., Croce,C.M.,
            Lanfrancone,L., Donti,E., Pengue,G., La Mantia,G., Pelicci,P.G. et
            al.
  TITLE     Chromosomal localization of four human zinc finger cDNAs
  JOURNAL   Hum Genet 91 (3), 217-222 (1993)
   PUBMED   8478004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK054606.1, BP351823.1, BC062309.1 and AI301044.1.
            
            On Nov 22, 2018 this sequence version replaced NM_007135.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK054606.1, SRR1660805.99508.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000342483.5/ ENSP00000362446.4
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-497               AK054606.1         1-497
            498-591             BP351823.1         468-561
            592-1188            AK054606.1         592-1188
            1189-2069           BC062309.1         1152-2032
            2070-2078           AI301044.1         14-22               c
FEATURES             Location/Qualifiers
     source          1..2078
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33.3"
     gene            1..2078
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /note="zinc finger protein 79"
                     /db_xref="GeneID:7633"
                     /db_xref="HGNC:HGNC:13153"
                     /db_xref="MIM:194552"
     exon            1..422
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /inference="alignment:Splign:2.1.0"
     CDS             407..1903
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /note="isoform a is encoded by transcript variant 1;
                     ZNFpT7"
                     /codon_start=1
                     /product="zinc finger protein 79 isoform a"
                     /protein_id="NP_009066.2"
                     /db_xref="CCDS:CCDS6871.1"
                     /db_xref="GeneID:7633"
                     /db_xref="HGNC:HGNC:13153"
                     /db_xref="MIM:194552"
                     /translation="MLEEGVLPSPGPALPQEENTGEEGMAAGLLTAGPRGSTFFSSVT
                     VAFAQERWRCLVSTPRDRFKEGIPGKSRSLVLLGLPVSQPGMNSQLEQREGAWMLEGE
                     DLRSPSPGWKIISGSPPEQALSEASFQDPCVEMPPGDSDHGTSDLEKSFNLRPVLSPQ
                     QRVPVEARPRKCETHTESFKNSEILKPHRAKPYACNECGKAFSYCSSLSQHQKSHTGE
                     KPYECSECGKAFSQSSSLIQHQRIHTGEKPYKCSECGRAFSQNANLTKHQRTHTGEKP
                     YRCSECEKAFSDCSALVQHQRIHTGEKPYECSDCGKAFRHSANLTNHQRTHTGEKPYK
                     CSECGKAFSYCAAFIQHQRIHTGEKPYRCAACGKAFSQSANLTNHQRTHTGEKPYKCS
                     ECGKAFSQSTNLIIHQKTHTGEKPYKCNECGKFFSESSALIRHHIIHTGEKPYECNEC
                     GKAFNQSSSLSQHQRIHTGVKPYECSECGKAFRCSSAFVRHQRLHAGE"
     exon            423..511
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /inference="alignment:Splign:2.1.0"
     exon            512..638
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /inference="alignment:Splign:2.1.0"
     exon            639..734
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /inference="alignment:Splign:2.1.0"
     exon            735..2078
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2050..2055
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /note="hexamer: AATAAA"
     polyA_site      2078
                     /gene="ZNF79"
                     /gene_synonym="pT7"
                     /note="major polyA site"
ORIGIN      
        1 aatcaggcgc gtccctctgg cgctggagcc aggacctggc gttgggcggt acttggacag
       61 cggttcttga gctctcgcgg ttgccggtag attgttgcca gttgccagtt gccagtcgtt
      121 tttcggaaag ctggcagcgg ctttttcacc gggttctgct tgaggccgag ccaaagagtg
      181 gctgtgactc gggagacgga gtggaacacc cggctgggca ggcccggaca gctcccgcga
      241 cccagcaccg caggatcaga ccgtgcctct gcggggagag gctggagagg aagagtccgg
      301 cctgggagcc gtcagagcag ccctgcagaa cggggtgggg gctgctgtag atagaccctt
      361 acgcccagag aactgctggg aggctgtggc gcgaggcggg actcaaatgc tggaggaagg
      421 agtactgcct tccccaggcc ctgcccttcc ccaagaggaa aacacaggag aggaaggaat
      481 ggctgctggt ctcctcacag ctgggccccg gggatccaca ttcttcagca gtgtgacggt
      541 agcttttgca caggaaaggt ggaggtgcct cgtgtctact ccacgggaca ggttcaagga
      601 ggggatacca ggaaagtcca ggagccttgt cctactagga cttccagttt cccagcctgg
      661 catgaactcc cagttggaac aaagggaagg cgcatggatg ctggagggcg aagacctgcg
      721 aagtccctct ccaggctgga agattatatc tggatcacca ccagagcaag ccctttctga
      781 agcttcattc caagacccat gtgtagagat gccccctggg gattcagacc acgggaccag
      841 tgaccttgag aagagcttca atctgagacc agtcctctct ccgcaacaga gagtgcccgt
      901 ggaagcgaga cctcgcaaat gtgagacaca caccgagagc ttcaagaact cggaaatcct
      961 gaaacctcac agagcaaaac catatgcatg taatgaatgt ggcaaagcct tcagttactg
     1021 ttcttccctt tctcagcatc agaagagcca cactggagag aagccctatg agtgcagtga
     1081 atgtgggaag gccttcagcc agagctcatc tctcattcag caccagagga ttcacactgg
     1141 agagaagcct tacaagtgca gtgaatgtgg aagagccttc agccagaacg ccaacctcac
     1201 caaacaccag cgaacccaca ccggagagaa gccctacaga tgcagcgagt gtgagaaagc
     1261 cttcagtgac tgctcagctc ttgttcagca tcagagaatt cataccggag agaagcccta
     1321 cgaatgcagc gactgtggga aggccttccg tcacagtgca aacctcacga accatcagag
     1381 gactcacacc ggggagaagc cctacaagtg cagcgagtgt gggaaggcct tcagttactg
     1441 cgcagcgttc attcagcacc agaggattca caccggggag aagccctaca gatgtgccgc
     1501 gtgtgggaag gccttcagcc agagtgcaaa cctcacaaac catcagagga ctcacactgg
     1561 ggagaaaccc tacaagtgca gcgagtgtgg gaaggccttc agccagagta ccaatctcat
     1621 aatccaccaa aagacccaca ccggggagaa gccatataaa tgtaatgaat gtgggaaatt
     1681 cttcagtgag agctcagccc tcattcggca tcatataatc cacaccggag aaaaacctta
     1741 tgagtgtaat gagtgtggta aagcgtttaa ccagagctca tcccttagtc agcatcagag
     1801 aatccacaca ggcgtgaaac cctacgaatg cagcgagtgt gggaaggcct tccggtgcag
     1861 ctctgccttc gttagacatc agagactcca cgccggagag taactaggaa catggtagaa
     1921 gtggagagag tcccggacat gccgactcag gacaggtggg tgaggatctg agaaatgcta
     1981 aaggcttgaa agcatctgaa gacatctaac ttagagtctg cagcccagag ccacatgcaa
     2041 aacaccttca ataaacagcc actatttcac atgctgta
//
