LOCUS       NM_213603               1616 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens zinc finger protein 789 (ZNF789), transcript variant
            1, mRNA.
ACCESSION   NM_213603
VERSION     NM_213603.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1616)
  AUTHORS   Bradic,M., Taleb,S., Thomas,B., Chidiac,O., Robay,A., Hassan,N.,
            Malek,J., Ait Hssain,A. and Abi Khalil,C.
  TITLE     DNA methylation predicts the outcome of COVID-19 patients with
            acute respiratory distress syndrome
  JOURNAL   J Transl Med 20 (1), 526 (2022)
   PUBMED   36371196
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1616)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1616)
  AUTHORS   Wang,A.G., Yoon,S.Y., Oh,J.H., Jeon,Y.J., Kim,M., Kim,J.M.,
            Byun,S.S., Yang,J.O., Kim,J.H., Kim,D.G., Yeom,Y.I., Yoo,H.S.,
            Kim,Y.S. and Kim,N.S.
  TITLE     Identification of intrahepatic cholangiocarcinoma related genes by
            comparison with normal liver tissues using expressed sequence tags
  JOURNAL   Biochem Biophys Res Commun 345 (3), 1022-1032 (2006)
   PUBMED   16712791
REFERENCE   4  (bases 1 to 1616)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC073063.12, AK093141.1, BC089424.1 and BI767175.1.
            
            On Nov 24, 2018 this sequence version replaced NM_213603.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163655.13568.1,
                                           SRR1803615.35776.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000331410.10/ ENSP00000331927.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC073063.12        45587-45588         c
            3-359               AK093141.1         1-357
            360-449             BC089424.1         320-409
            450-543             BI767175.1         313-406
            544-1605            BC089424.1         504-1565
            1606-1616           AC073063.12        30873-30883         c
FEATURES             Location/Qualifiers
     source          1..1616
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..1616
                     /gene="ZNF789"
                     /note="zinc finger protein 789"
                     /db_xref="GeneID:285989"
                     /db_xref="HGNC:HGNC:27801"
     exon            1..167
                     /gene="ZNF789"
                     /inference="alignment:Splign:2.1.0"
     exon            168..245
                     /gene="ZNF789"
                     /inference="alignment:Splign:2.1.0"
     CDS             222..1499
                     /gene="ZNF789"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 789 isoform 1"
                     /protein_id="NP_998768.2"
                     /db_xref="CCDS:CCDS34693.1"
                     /db_xref="GeneID:285989"
                     /db_xref="HGNC:HGNC:27801"
                     /translation="MFPPARGKELLSFEDVAMYFTREEWGHLNWGQKDLYRDVMLENY
                     RNMVLLGFQFPKPEMICQLENWDEQWILDLPRTGNRKASGSACPGSEARHKMKKLTPK
                     QKFSEDLESYKISVVMQESAEKLSEKLHKCKEFVDSCRLTFPTSGDEYSRGFLQNLNL
                     IQDQNAQTRWKQGRYDEDGKPFNQRSLLLGHERILTRAKSYECSECGKVIRRKAWFDQ
                     HQRIHFLENPFECKVCGQAFRQRSALTVHKQCHLQNKPYRCHDCGKCFRQLAYLVEHK
                     RIHTKEKPYKCSKCEKTFSQNSTLIRHQVIHSGEKRHKCLECGKAFGRHSTLLCHQQI
                     HSKPNTHKCSECGQSFGRNVDLIQHQRIHTKEEFFQCGECGKTFSFKRNLFRHQVIHT
                     GSQPYQCVICGKSFKWHTSFIKHQGTHKGQIST"
     exon            246..372
                     /gene="ZNF789"
                     /inference="alignment:Splign:2.1.0"
     exon            373..486
                     /gene="ZNF789"
                     /inference="alignment:Splign:2.1.0"
     exon            487..1616
                     /gene="ZNF789"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1586..1591
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ZNF789"
                     /note="hexamer: AATAAA"
     polyA_site      1616
                     /gene="ZNF789"
                     /note="major polyA site"
ORIGIN      
        1 agcgagaggc tctgaggctg ccagagtggt tgtgtctgtt cctccggtaa ggggtgattc
       61 gccgaggggc gcggaccaga cagacctcgg gtcaggcccg ggaaccccga gaggagagcc
      121 cagcccctgg tggaggcggc ttggcggaga ttcggagccg tcagcagctc agccagacgt
      181 ccaggatccc accccttgca aaagaccagg ccgtggaagc catgttccca ccagccaggg
      241 ggaaggagct gctctcgttt gaggatgtgg cgatgtactt caccagagag gagtggggcc
      301 acctcaactg gggtcagaag gacctctacc gagatgtgat gttggagaac tacaggaaca
      361 tggtcttgct gggatttcag tttcccaaac ctgagatgat ctgtcagctg gagaactggg
      421 acgagcagtg gatcctggat ctaccgagaa ctgggaatag gaaggcttcc ggtagtgctt
      481 gcccaggttc tgaagccaga cacaagatga aaaagctaac tccaaaacag aaattttctg
      541 aagatttaga gtcatataag atatcagtgg taatgcagga atcagctgag aaactttcag
      601 aaaagttaca taagtgtaaa gaatttgtgg acagttgcag gcttactttc cctactagtg
      661 gtgatgaata cagcaggggc ttccttcaaa accttaacct tattcaagat cagaatgcgc
      721 aaacaaggtg gaagcagggc agatatgatg aggatggcaa acccttcaat caaagatctt
      781 tgcttttggg gcatgagcga attctcacaa gagcaaagtc ttatgaatgc agtgaatgtg
      841 gaaaagtcat taggcgtaag gcatggtttg atcaacatca aagaattcac tttttagaga
      901 atccttttga gtgtaaggtc tgtgggcaag ccttcagaca gcggtcagct cttacggtcc
      961 ataaacagtg tcacctgcaa aacaagccat acagatgtca tgactgtgga aagtgttttc
     1021 ggcagctcgc gtatcttgtt gaacataaga ggattcacac caaagaaaaa ccttataaat
     1081 gtagcaaatg tgaaaaaacg tttagtcaga attcaaccct tattcgacat caggtgatcc
     1141 atagtggaga aaaacgccat aaatgccttg agtgtggaaa agcctttggc cggcattcaa
     1201 cccttctatg tcatcaacag attcacagta aaccgaacac ccataaatgc agtgaatgtg
     1261 gacagtcctt tggtaggaat gtggatctca ttcagcatca aagaatccat acaaaggagg
     1321 aattctttca atgtggagaa tgtgggaaaa cgtttagttt taagaggaat ctttttcgac
     1381 atcaggtcat tcacactgga agccaaccct accaatgtgt catatgtgga aaatctttca
     1441 agtggcacac aagctttatt aagcaccagg gcactcacaa aggacagata tccacatgat
     1501 gttaattgga aagcagtcat tggagaacta gaacttataa acctctactt caagtgtgta
     1561 tcacgtaatt gtttccatga aaagcaataa atgtaacaaa gggtttttct atggga
//
